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The map label for this gene is qseD [H]

Identifier: 120612712

GI number: 120612712

Start: 4526742

End: 4527680

Strand: Reverse

Name: qseD [H]

Synonym: Aave_4075

Alternate gene names: 120612712

Gene position: 4527680-4526742 (Counterclockwise)

Preceding gene: 120612716

Following gene: 120612711

Centisome position: 84.59

GC content: 67.73

Gene sequence:

>939_bases
ATGGAAACCAAGTGGCTCGAGGACTTTGTCAGCCTCGCGGAGACGCGCAGCTTCAGCCGGTCGGCGCAACTGCGGCATGT
AACCCAGCCCGCGTTCTCGCGGCGCATCCAGGCGCTGGAAGCCTGGGCCGGAACCGATCTGGTGGATCGCAGTTCCTATC
CCACCCGGCTCACGCCGGCGGGCAGGACCCTCTACGAGGAGGCGCTGGACATGCTGCAGTCGCTGCAGAACACGCGGGCG
ATGCTGAGGGCGCACACCAGCGCCGACAAGGACATGGTCGAGTTCGCGGTTCCGCACACGCTGGCCTTCACGTTCTTTCC
TGCCTGGCTTTCCGGGCTGCGCGAGCGCTTCGGACCGGTGAAGAGCCGGCTGATCGCCCTCAACGTGCACGACGCGGTGC
TGCGCCTGGTGGAAGGGGGCTGCGACCTGCTGATCGCCTACCACCACCCCTCGCAGCCCTTGCAGCTGGATTCCGACCGG
TACGAGATGCTCACGCTCGGTCAGGAAGTCCTGTCGCCCTATGCGCGGGCGGACGCCGATGGCCGGCCGCTCTACGCGCT
GCCAGGCGAGCCGGGCCATCCGCTGCCCTATCTGGGCTATGCGCCGGGGGCTTACCTGGGCCGGGTGACGGAACTCATCC
TCAAGCAGTCCGGCATTCCCATCCACCTGGACCGCGTGTACGAGACCGACATGGCCGAGGGCCTCAAGGCCATGGCGCTG
GAAGGACATGGGGTTGCCTTCCTGCCGCACAGCGCGGTGAAGAAGGAGCTGCGCTCGCGCCGGCTGGCCAGTGCGGTGCT
CGAAGGCGTGCCGGACATGCAGATGGCCATGGAGGTGCGGGCCTACCGGCAGAGGCCTTCGGGCAAGGAGCGCGCCAAGG
GCACGGCGGAGGCCCTCTGGACCTACCTGCAGGCACACGGTACCGACAAACCGCTGTAG

Upstream 100 bases:

>100_bases
CAACGCGGCGCGGCGCGATCGGCATGCTTGCGAATGCAGTACATGATTTCCCGAAGTGCGCTCGACCTTGCGGATGCCGC
GGAGCCGATAATGGCGCCCC

Downstream 100 bases:

>100_bases
CATGCGCTGACTTGGTTATGTCTCGATTGCATGATGTAATCCTGCAATCGGCATTGGAAAGAGGTGGGGGACAGGACTTA
CAGTCCCGACCGGCTCCAGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Quorum-sensing regulator protein D [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
METKWLEDFVSLAETRSFSRSAQLRHVTQPAFSRRIQALEAWAGTDLVDRSSYPTRLTPAGRTLYEEALDMLQSLQNTRA
MLRAHTSADKDMVEFAVPHTLAFTFFPAWLSGLRERFGPVKSRLIALNVHDAVLRLVEGGCDLLIAYHHPSQPLQLDSDR
YEMLTLGQEVLSPYARADADGRPLYALPGEPGHPLPYLGYAPGAYLGRVTELILKQSGIPIHLDRVYETDMAEGLKAMAL
EGHGVAFLPHSAVKKELRSRRLASAVLEGVPDMQMAMEVRAYRQRPSGKERAKGTAEALWTYLQAHGTDKPL

Sequences:

>Translated_312_residues
METKWLEDFVSLAETRSFSRSAQLRHVTQPAFSRRIQALEAWAGTDLVDRSSYPTRLTPAGRTLYEEALDMLQSLQNTRA
MLRAHTSADKDMVEFAVPHTLAFTFFPAWLSGLRERFGPVKSRLIALNVHDAVLRLVEGGCDLLIAYHHPSQPLQLDSDR
YEMLTLGQEVLSPYARADADGRPLYALPGEPGHPLPYLGYAPGAYLGRVTELILKQSGIPIHLDRVYETDMAEGLKAMAL
EGHGVAFLPHSAVKKELRSRRLASAVLEGVPDMQMAMEVRAYRQRPSGKERAKGTAEALWTYLQAHGTDKPL
>Mature_312_residues
METKWLEDFVSLAETRSFSRSAQLRHVTQPAFSRRIQALEAWAGTDLVDRSSYPTRLTPAGRTLYEEALDMLQSLQNTRA
MLRAHTSADKDMVEFAVPHTLAFTFFPAWLSGLRERFGPVKSRLIALNVHDAVLRLVEGGCDLLIAYHHPSQPLQLDSDR
YEMLTLGQEVLSPYARADADGRPLYALPGEPGHPLPYLGYAPGAYLGRVTELILKQSGIPIHLDRVYETDMAEGLKAMAL
EGHGVAFLPHSAVKKELRSRRLASAVLEGVPDMQMAMEVRAYRQRPSGKERAKGTAEALWTYLQAHGTDKPL

Specific function: Down-regulates expression of the flagellar regulon, decreasing motility [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790783, Length=304, Percent_Identity=30.9210526315789, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI145693105, Length=147, Percent_Identity=27.2108843537415, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI145693193, Length=270, Percent_Identity=24.8148148148148, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34820; Mature: 34820

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METKWLEDFVSLAETRSFSRSAQLRHVTQPAFSRRIQALEAWAGTDLVDRSSYPTRLTPA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
GRTLYEEALDMLQSLQNTRAMLRAHTSADKDMVEFAVPHTLAFTFFPAWLSGLRERFGPV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
KSRLIALNVHDAVLRLVEGGCDLLIAYHHPSQPLQLDSDRYEMLTLGQEVLSPYARADAD
HHHEEEEEHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
GRPLYALPGEPGHPLPYLGYAPGAYLGRVTELILKQSGIPIHLDRVYETDMAEGLKAMAL
CCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHEE
EGHGVAFLPHSAVKKELRSRRLASAVLEGVPDMQMAMEVRAYRQRPSGKERAKGTAEALW
CCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHCHHHHHHH
TYLQAHGTDKPL
HHHHHCCCCCCC
>Mature Secondary Structure
METKWLEDFVSLAETRSFSRSAQLRHVTQPAFSRRIQALEAWAGTDLVDRSSYPTRLTPA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
GRTLYEEALDMLQSLQNTRAMLRAHTSADKDMVEFAVPHTLAFTFFPAWLSGLRERFGPV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
KSRLIALNVHDAVLRLVEGGCDLLIAYHHPSQPLQLDSDRYEMLTLGQEVLSPYARADAD
HHHEEEEEHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
GRPLYALPGEPGHPLPYLGYAPGAYLGRVTELILKQSGIPIHLDRVYETDMAEGLKAMAL
CCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHEE
EGHGVAFLPHSAVKKELRSRRLASAVLEGVPDMQMAMEVRAYRQRPSGKERAKGTAEALW
CCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHCHHHHHHH
TYLQAHGTDKPL
HHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 7876157 [H]