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The map label for this gene is erpA [H]

Identifier: 120612686

GI number: 120612686

Start: 4501018

End: 4501383

Strand: Reverse

Name: erpA [H]

Synonym: Aave_4049

Alternate gene names: 120612686

Gene position: 4501383-4501018 (Counterclockwise)

Preceding gene: 120612687

Following gene: 120612685

Centisome position: 84.09

GC content: 61.75

Gene sequence:

>366_bases
ATGAGCGCAGTAGCCGAGAACATCCAGACCGAAATGCCCGCCCCCATCGTCTTCACCGACAGTGCAGCCGCCAAGGTGGC
CGACCTGATCGCCGAAGAGGGCAATCCCGACCTGAAGCTCCGCGTATTCGTGCAAGGCGGCGGCTGCTCGGGCTTCCAGT
ACGGCTTCACGTTCGACGAGATCACGAACGAGGACGACACCACCATGACGAAGAACGGCGTTTCGCTGCTGATCGACGCC
ATGAGCTACCAGTACCTGGTGGGCGCCGAGATCGACTACAAGGAAGACCTGCAGGGCGCCCAGTTCGTCATCAAGAACCC
GAACGCCACCACCACCTGCGGCTGCGGATCGAGCTTCTCGGTCTGA

Upstream 100 bases:

>100_bases
AAGCCCACACTCAAATTGGCGTCAAAGGCAGGCTGAACGGCGTGAAAACGCCATTGCAGTACCATCGAGCCCAATTCCTC
CCCTCAGCCGGAGACACCCC

Downstream 100 bases:

>100_bases
CCGCCTCCGTGTGAGAGCAAGCCGCCCGAGGGCGGCTTTTTTGTTCCTGCAGAAGCCGTCTCTCCCCCATGTCCTCCAGC
TCCGCAGCCGAGATATCCCC

Product: iron-sulfur cluster insertion protein ErpA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 121; Mature: 120

Protein sequence:

>121_residues
MSAVAENIQTEMPAPIVFTDSAAAKVADLIAEEGNPDLKLRVFVQGGGCSGFQYGFTFDEITNEDDTTMTKNGVSLLIDA
MSYQYLVGAEIDYKEDLQGAQFVIKNPNATTTCGCGSSFSV

Sequences:

>Translated_121_residues
MSAVAENIQTEMPAPIVFTDSAAAKVADLIAEEGNPDLKLRVFVQGGGCSGFQYGFTFDEITNEDDTTMTKNGVSLLIDA
MSYQYLVGAEIDYKEDLQGAQFVIKNPNATTTCGCGSSFSV
>Mature_120_residues
SAVAENIQTEMPAPIVFTDSAAAKVADLIAEEGNPDLKLRVFVQGGGCSGFQYGFTFDEITNEDDTTMTKNGVSLLIDAM
SYQYLVGAEIDYKEDLQGAQFVIKNPNATTTCGCGSSFSV

Specific function: Required for insertion of 4Fe-4S clusters (Potential) [H]

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family [H]

Homologues:

Organism=Homo sapiens, GI160420328, Length=107, Percent_Identity=39.2523364485981, Blast_Score=86, Evalue=1e-17,
Organism=Homo sapiens, GI52426768, Length=121, Percent_Identity=30.5785123966942, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786351, Length=111, Percent_Identity=61.2612612612613, Blast_Score=153, Evalue=3e-39,
Organism=Escherichia coli, GI1788877, Length=106, Percent_Identity=35.8490566037736, Blast_Score=70, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71998452, Length=108, Percent_Identity=37.962962962963, Blast_Score=79, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI193209025, Length=113, Percent_Identity=30.9734513274336, Blast_Score=76, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI25146411, Length=111, Percent_Identity=29.7297297297297, Blast_Score=73, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323001, Length=109, Percent_Identity=34.8623853211009, Blast_Score=71, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24649697, Length=83, Percent_Identity=48.1927710843374, Blast_Score=81, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24642263, Length=109, Percent_Identity=33.0275229357798, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063 [H]

Pfam domain/function: PF01521 Fe-S_biosyn [H]

EC number: NA

Molecular weight: Translated: 12908; Mature: 12776

Theoretical pI: Translated: 3.77; Mature: 3.77

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVAENIQTEMPAPIVFTDSAAAKVADLIAEEGNPDLKLRVFVQGGGCSGFQYGFTFDE
CCCHHHHHHHCCCCCEEEECCHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCHHH
ITNEDDTTMTKNGVSLLIDAMSYQYLVGAEIDYKEDLQGAQFVIKNPNATTTCGCGSSFS
HCCCCCCEEECCCCEEEEECCCCEEEECCCCCCHHCCCCCEEEEECCCCCEEECCCCCCC
V
C
>Mature Secondary Structure 
SAVAENIQTEMPAPIVFTDSAAAKVADLIAEEGNPDLKLRVFVQGGGCSGFQYGFTFDE
CCHHHHHHHCCCCCEEEECCHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCHHH
ITNEDDTTMTKNGVSLLIDAMSYQYLVGAEIDYKEDLQGAQFVIKNPNATTTCGCGSSFS
HCCCCCCEEECCCCEEEEECCCCEEEECCCCCCHHCCCCCEEEEECCCCCEEECCCCCCC
V
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA