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The map label for this gene is qseC [H]

Identifier: 120612602

GI number: 120612602

Start: 4392466

End: 4393893

Strand: Reverse

Name: qseC [H]

Synonym: Aave_3963

Alternate gene names: 120612602

Gene position: 4393893-4392466 (Counterclockwise)

Preceding gene: 120612603

Following gene: 120612601

Centisome position: 82.09

GC content: 75.49

Gene sequence:

>1428_bases
ATGGACGCCCTGTCCGCGCGCGCGCCGCATTCGCTGCGGGCGCGGCTGCTGTGCTTCCTGTTCGTGGCGATCGTCTGCGC
GGCGCTGCTGCAGTTCGCGCTCGCCTACCGCTCGGCGCTGGCCGAGGCGGACCAGATTTTCGACTACCACATGCAGCAGA
CGGCGATGGCGCTGCGCCCCGGCGTGCCGGCCATGGCGGAGGGCACGCCGGAGCCGCTGGAGCAGGAGGAGGAGGAGGAG
AGTACCGAGTTCGTGGTGCAGATCTGGTCGTCCGACGGGTTGCGGGTGTTCGAATCGTCCGTGGGCGCGGCGCTGCCGCA
GCGCGCGGTGCTGGGTTTCTCGAACGTGCGCGCGCACGGCACCACCTACCGCGTGTTCTCTGTGCAGACGCGCTCGCAGG
TGATCCAGGTGGCGCAGGACATGGCCGCGCGCCGCGAGATGGCGCGCGACCTGGCCTGGCGCACGGCGGGGCCGATCGCG
CTGCTGGCGCCCCTGCTGGCGCTGGCCGTGTGGTGGGCGGTGAGCGGCTCGCTCGCGCCGGTGGAGCGGGTGCGGCGGCA
ACTGGCGAAGCGGCAGGCGGACGACCTGTCGCCCGTGCATGCGGGCGCGCTGCCGGACGAGGTGCGGCCGATGGTGGACG
AGCTGAACCTGCTGTTCGAGCGCGTGCGCCGGGCCTTCGAGGCGCAGCAGCATTTCGTGGCGGATGCGGCGCACGAGCTG
CGCTCGCCGCTGGCGGCGCTCAAGCTGCAGCTGCAGGGCCTGCAGCGCGCGGGCAGCGAAGAGGCGCGCGCGGTGGCGGC
GGGGCGGCTCGCGGCCGGCATCGACCGTGCCACGCGCCTCGTGGAGCAGTTGCTGGCCCTGGCGCGGCAGGAGGCCAGCG
CCGCCGCCGGCACGCCGCCCGAGCCCGTGCCCCTGGCCGGCCTCGCCCGGCAGGCCGTGGCCGATGCCACGCCGGCCGCG
CAGCACAAGAACATCGACCTGGGCCTGGTGACCGGCGACGCGGTGGCGGTGCTGGGGTATGCGGATGCGCTGCGCATCCT
GCTGCGCAACCTGGTGGACAACGCCGTGAAGTACACGCCCGACGGCGGCGTGGTGGACGTACACGTGCGCGAAGTGACCG
CAGGTCCGGGGCCTGCCGGCGTGGAGCTGGTGGTGGAAGACAGCGGCCCCGGGATCGCCGAGGACGACCGCGAGCGCGTG
CTGGGGCGCTTCTACCGCGCGCCCGCGGCGGCCGGCAGCGCGCCGGTGGGGGGCAGCGGGCTGGGCCTGGCGATCGTGGA
GTCGATCGCGCGGCTGCATGGCGCTGCGGTAGCGCTGGACGCCTCGCCGCGCCTGGGCGGGCTGCGCGTGGCGGTGCGCT
TCGCGGTGGCGGCCGGCGTTCCGGCGCTGCCGGGCGGGGGCACGGGGGGCCCGGGGGGCGGCGCTTGA

Upstream 100 bases:

>100_bases
TATGAGCGGAGCGGTGGACAGCGGCCCGGGCGAGGGGCACGGCGAGGCGTCGGCCGGTGCCTCCACGCCGGCCGCCCGCG
CGCGCCGCCGCGACCGCTGG

Downstream 100 bases:

>100_bases
CGCGCTTCGCGCTGCTTTCGGGCCTGGGGCATGCGGTTTTCGTGGCCGTGGGCCTGCTGATCTACGTGATGGCCACGCGC
ATCGGCCGCCAGCGCCGCCA

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 475

Protein sequence:

>475_residues
MDALSARAPHSLRARLLCFLFVAIVCAALLQFALAYRSALAEADQIFDYHMQQTAMALRPGVPAMAEGTPEPLEQEEEEE
STEFVVQIWSSDGLRVFESSVGAALPQRAVLGFSNVRAHGTTYRVFSVQTRSQVIQVAQDMAARREMARDLAWRTAGPIA
LLAPLLALAVWWAVSGSLAPVERVRRQLAKRQADDLSPVHAGALPDEVRPMVDELNLLFERVRRAFEAQQHFVADAAHEL
RSPLAALKLQLQGLQRAGSEEARAVAAGRLAAGIDRATRLVEQLLALARQEASAAAGTPPEPVPLAGLARQAVADATPAA
QHKNIDLGLVTGDAVAVLGYADALRILLRNLVDNAVKYTPDGGVVDVHVREVTAGPGPAGVELVVEDSGPGIAEDDRERV
LGRFYRAPAAAGSAPVGGSGLGLAIVESIARLHGAAVALDASPRLGGLRVAVRFAVAAGVPALPGGGTGGPGGGA

Sequences:

>Translated_475_residues
MDALSARAPHSLRARLLCFLFVAIVCAALLQFALAYRSALAEADQIFDYHMQQTAMALRPGVPAMAEGTPEPLEQEEEEE
STEFVVQIWSSDGLRVFESSVGAALPQRAVLGFSNVRAHGTTYRVFSVQTRSQVIQVAQDMAARREMARDLAWRTAGPIA
LLAPLLALAVWWAVSGSLAPVERVRRQLAKRQADDLSPVHAGALPDEVRPMVDELNLLFERVRRAFEAQQHFVADAAHEL
RSPLAALKLQLQGLQRAGSEEARAVAAGRLAAGIDRATRLVEQLLALARQEASAAAGTPPEPVPLAGLARQAVADATPAA
QHKNIDLGLVTGDAVAVLGYADALRILLRNLVDNAVKYTPDGGVVDVHVREVTAGPGPAGVELVVEDSGPGIAEDDRERV
LGRFYRAPAAAGSAPVGGSGLGLAIVESIARLHGAAVALDASPRLGGLRVAVRFAVAAGVPALPGGGTGGPGGGA
>Mature_475_residues
MDALSARAPHSLRARLLCFLFVAIVCAALLQFALAYRSALAEADQIFDYHMQQTAMALRPGVPAMAEGTPEPLEQEEEEE
STEFVVQIWSSDGLRVFESSVGAALPQRAVLGFSNVRAHGTTYRVFSVQTRSQVIQVAQDMAARREMARDLAWRTAGPIA
LLAPLLALAVWWAVSGSLAPVERVRRQLAKRQADDLSPVHAGALPDEVRPMVDELNLLFERVRRAFEAQQHFVADAAHEL
RSPLAALKLQLQGLQRAGSEEARAVAAGRLAAGIDRATRLVEQLLALARQEASAAAGTPPEPVPLAGLARQAVADATPAA
QHKNIDLGLVTGDAVAVLGYADALRILLRNLVDNAVKYTPDGGVVDVHVREVTAGPGPAGVELVVEDSGPGIAEDDRERV
LGRFYRAPAAAGSAPVGGSGLGLAIVESIARLHGAAVALDASPRLGGLRVAVRFAVAAGVPALPGGGTGGPGGGA

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=467, Percent_Identity=32.5481798715203, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI1790551, Length=298, Percent_Identity=30.5369127516779, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1788393, Length=279, Percent_Identity=30.4659498207885, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI1786600, Length=216, Percent_Identity=35.1851851851852, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786783, Length=303, Percent_Identity=31.023102310231, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1790346, Length=241, Percent_Identity=29.8755186721992, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1787374, Length=312, Percent_Identity=26.6025641025641, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1790861, Length=296, Percent_Identity=30.0675675675676, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1787894, Length=255, Percent_Identity=29.8039215686275, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1789149, Length=244, Percent_Identity=27.4590163934426, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1790436, Length=215, Percent_Identity=30.6976744186047, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788713, Length=248, Percent_Identity=24.1935483870968, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI87082128, Length=326, Percent_Identity=28.5276073619632, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1789808, Length=244, Percent_Identity=25.8196721311475, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49782; Mature: 49782

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDALSARAPHSLRARLLCFLFVAIVCAALLQFALAYRSALAEADQIFDYHMQQTAMALRP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GVPAMAEGTPEPLEQEEEEESTEFVVQIWSSDGLRVFESSVGAALPQRAVLGFSNVRAHG
CCCCCCCCCCCCCHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHCCHHHHHCHHHHCCCC
TTYRVFSVQTRSQVIQVAQDMAARREMARDLAWRTAGPIALLAPLLALAVWWAVSGSLAP
CEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCH
VERVRRQLAKRQADDLSPVHAGALPDEVRPMVDELNLLFERVRRAFEAQQHFVADAAHEL
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSPLAALKLQLQGLQRAGSEEARAVAAGRLAAGIDRATRLVEQLLALARQEASAAAGTPP
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
EPVPLAGLARQAVADATPAAQHKNIDLGLVTGDAVAVLGYADALRILLRNLVDNAVKYTP
CCCCHHHHHHHHHHCCCCCHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHEECC
DGGVVDVHVREVTAGPGPAGVELVVEDSGPGIAEDDRERVLGRFYRAPAAAGSAPVGGSG
CCCEEEEEEEEEECCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
LGLAIVESIARLHGAAVALDASPRLGGLRVAVRFAVAAGVPALPGGGTGGPGGGA
HHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDALSARAPHSLRARLLCFLFVAIVCAALLQFALAYRSALAEADQIFDYHMQQTAMALRP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GVPAMAEGTPEPLEQEEEEESTEFVVQIWSSDGLRVFESSVGAALPQRAVLGFSNVRAHG
CCCCCCCCCCCCCHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHCCHHHHHCHHHHCCCC
TTYRVFSVQTRSQVIQVAQDMAARREMARDLAWRTAGPIALLAPLLALAVWWAVSGSLAP
CEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCH
VERVRRQLAKRQADDLSPVHAGALPDEVRPMVDELNLLFERVRRAFEAQQHFVADAAHEL
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSPLAALKLQLQGLQRAGSEEARAVAAGRLAAGIDRATRLVEQLLALARQEASAAAGTPP
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
EPVPLAGLARQAVADATPAAQHKNIDLGLVTGDAVAVLGYADALRILLRNLVDNAVKYTP
CCCCHHHHHHHHHHCCCCCHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHEECC
DGGVVDVHVREVTAGPGPAGVELVVEDSGPGIAEDDRERVLGRFYRAPAAAGSAPVGGSG
CCCEEEEEEEEEECCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
LGLAIVESIARLHGAAVALDASPRLGGLRVAVRFAVAAGVPALPGGGTGGPGGGA
HHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]