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The map label for this gene is fhuA [H]

Identifier: 120612556

GI number: 120612556

Start: 4340069

End: 4342261

Strand: Direct

Name: fhuA [H]

Synonym: Aave_3917

Alternate gene names: 120612556

Gene position: 4340069-4342261 (Clockwise)

Preceding gene: 120612555

Following gene: 120612557

Centisome position: 81.08

GC content: 69.72

Gene sequence:

>2193_bases
ATGATCCACCTCCGTCCCGGCGCAGCGTTTCAGCGCGCCGCCGCCCTGGCTTTGCCGCGCCGTCCTGCCCGCTCCACCCT
CCCTGCGCTCCGCTTGGGCCGCCACGCCCTGACCCCGCTGGCGCTCTGCCTGTCGCAGGCCGCGTTCGCCCAGTCCGGCA
CCGCTGTGGACGGCACCGCGCAGTCTCCCGCGCAATTGCAGGAAGTGCGCATCAACGCCGGCACCGAGAAGGACGTGGGC
TTCGCTCCGACCGAAGCCCAGACGGCCGGCAAGATGCCGATGCGCCGGCTGGAGACGCCGCAGTCGGTCGGCGTGGTGAC
GCGCGAGCAGATGGAGTCGCGCCAGATCACCAACCTGCAGCAGGCGCTGCAGACCGTGGCGGGCGTGAGCCCCGTGAACT
TCGGCCGCCGCGGCGTGGACGACCTCAACATCCGCGGCTTCCGCTCCACCGAATCCGTGCTGATCGACGGGCTGGTGCAG
AGCGTCGGCATGTGGACACGCCTGAACCCCTACGGCTACGAGCGTTTCGAGGTGCTCAAGGGTGCGGCATCGGTGCTCTA
CGGCCAGGTGCAGCCCGGCGGCATCGTCAACGCGGTGAGCAAGCGGCCCAGGCGCGAGGCGCTCACCGAGGTGGGCGTGG
AGGTGGGCAGCTTCGGACAGCGCACGCTGCAGGCAGACCTGAACCGGCCGCTGAACGAATCCGGCAAGGCGGCCTTCCGC
ATCAACGCGCAGGTGGCCAACAGCGACGACCCGACCGATTTCATCTACCGCCGCGACCGCTGGATCGCGCCCTCGCTGTC
GCTGGACTTAGGGCCGCAGACCGACCTGGTGGTGTTCGCCACCTACAACCAGAGCCAGTGGATGCGCCAGCAGGGCGTCA
CGCCCTACGGCACGGTGCTGCCCAACCGCAACGGCCCGGTGCGGCGCACGCTCTACACGGGCGACCCCAGCTTCGGCGGA
TACGACATCGAGACCAAGTCGCTGGGCTACGCGCTGGAGCACCGCTTCTCGCCCGCGCTCACGCTGCGCCAGAACGTGCG
CTACGAGACCGAGGGCGGCACCGGCAACCTCGTCGCCAACTCCACGCTGCAGTCGAACCAGCGCCTGCAGAACCGCACCG
CCACGCGCCAGTACATGGACGACGAGATGCTGGCCACCGACACCTCGGTGCTGGCGAAGTTCGCGGCCCTCGGCGTGCAG
CACCAGCTGGTGGCCGGGCTGGACGCGCGCACCGGCAAGAGCTGGCTGGGCCGCCGCACCTGCAGCATCGCGCCGATGGA
CCTGTTCAACCCGGTGTACGGCGTGGCGGCGCGCTGCCCCGCGGGGCTGACGATCGACGCGCCGGAGCGGCTCACCGTGG
CGGGTCTCTACGCGCAGGACCAGATCAGGCTCACGCCGCAGTGGACCGTCCTGGCGGGCCTGCGCCGCGACTGGTCCACC
AACACCATCGATGACCGCATCGCGCGGGAGAAGACACGGCAGAAGGACTCCGCCACCACGCTGTCCGCCGGCGTGGTGTA
CGAGTTCGTGCCCGGCTGGGCCGCCTACGCGAGCTACGGCGAATCGTTCCTGCCCGTGTCGGGCACCAGCTTCTCGGGCG
CGCCGTTCGTTCCCGAAACCGGCAAGCAGTGGGAAACCGGCCTGAAGTACGAAGCTCCCGACCGCAGCGTCACCGGTTCG
CTGGCCCTGTTCGACCTGAAGCGCAGCAACGTCACCACCGCCGACCCGGTGAACGCCACGTTCCAGGTGCAGACCGGAAC
GCAGCGCGCGCGCGGGCTGGAGCTGGAAGTGGGCGCCGAGCTGCAGCGCCACTGGAAGCTCACGGGCGCCTACACCTACA
CCGACTCGGAGGTCACGCGCGACAACAATGCCGCCATCGTCGGCAAGCCGCTCAACCTGACGCCGCGCAGCACGTTCGCC
CTGTGGGCCACCTACCAGCTGCCGCAGATGCCGCAGCTCACGCTGGGCGCGGGCGCCCGCCACGTGACCCGGCAGGTCGG
CTCCTATCCGTTCTCCCTGCCCGCCTACACGGTGGTGGATTTGTCCGTCGGCTACACCGGGCCCAGCTACCGCATCACGG
CCGGCGTGAAGAACGTGTTCGACCGGGCCTACTACGACGGCGCGATCAACGCCAACGTCGTCTCGCCCTCGCTGCCGCGC
AACTTCAGCGTAGGCCTGACGTACTTCTTCTGA

Upstream 100 bases:

>100_bases
TTAAATACGAATTATTCTCAAAAAAATTCATAGCTCCGATGCCACACGGGATTCCGGGATCCTTCCCGCGCCGGTGCGGC
ATCTTTTTTTCCGCCGTTCC

Downstream 100 bases:

>100_bases
CGCCTGACGCTCCCGCCCTGCGCGGCGCCCTCCCGCCGCACGGCCAGCCGGCACGCCCATGACCAGCCAGCGCACGATGC
ACCGCCTGCTCACGCTCCAC

Product: TonB-dependent siderophore receptor

Products: NA

Alternate protein names: Ferric hydroxamate receptor; Ferric hydroxamate uptake [H]

Number of amino acids: Translated: 730; Mature: 730

Protein sequence:

>730_residues
MIHLRPGAAFQRAAALALPRRPARSTLPALRLGRHALTPLALCLSQAAFAQSGTAVDGTAQSPAQLQEVRINAGTEKDVG
FAPTEAQTAGKMPMRRLETPQSVGVVTREQMESRQITNLQQALQTVAGVSPVNFGRRGVDDLNIRGFRSTESVLIDGLVQ
SVGMWTRLNPYGYERFEVLKGAASVLYGQVQPGGIVNAVSKRPRREALTEVGVEVGSFGQRTLQADLNRPLNESGKAAFR
INAQVANSDDPTDFIYRRDRWIAPSLSLDLGPQTDLVVFATYNQSQWMRQQGVTPYGTVLPNRNGPVRRTLYTGDPSFGG
YDIETKSLGYALEHRFSPALTLRQNVRYETEGGTGNLVANSTLQSNQRLQNRTATRQYMDDEMLATDTSVLAKFAALGVQ
HQLVAGLDARTGKSWLGRRTCSIAPMDLFNPVYGVAARCPAGLTIDAPERLTVAGLYAQDQIRLTPQWTVLAGLRRDWST
NTIDDRIAREKTRQKDSATTLSAGVVYEFVPGWAAYASYGESFLPVSGTSFSGAPFVPETGKQWETGLKYEAPDRSVTGS
LALFDLKRSNVTTADPVNATFQVQTGTQRARGLELEVGAELQRHWKLTGAYTYTDSEVTRDNNAAIVGKPLNLTPRSTFA
LWATYQLPQMPQLTLGAGARHVTRQVGSYPFSLPAYTVVDLSVGYTGPSYRITAGVKNVFDRAYYDGAINANVVSPSLPR
NFSVGLTYFF

Sequences:

>Translated_730_residues
MIHLRPGAAFQRAAALALPRRPARSTLPALRLGRHALTPLALCLSQAAFAQSGTAVDGTAQSPAQLQEVRINAGTEKDVG
FAPTEAQTAGKMPMRRLETPQSVGVVTREQMESRQITNLQQALQTVAGVSPVNFGRRGVDDLNIRGFRSTESVLIDGLVQ
SVGMWTRLNPYGYERFEVLKGAASVLYGQVQPGGIVNAVSKRPRREALTEVGVEVGSFGQRTLQADLNRPLNESGKAAFR
INAQVANSDDPTDFIYRRDRWIAPSLSLDLGPQTDLVVFATYNQSQWMRQQGVTPYGTVLPNRNGPVRRTLYTGDPSFGG
YDIETKSLGYALEHRFSPALTLRQNVRYETEGGTGNLVANSTLQSNQRLQNRTATRQYMDDEMLATDTSVLAKFAALGVQ
HQLVAGLDARTGKSWLGRRTCSIAPMDLFNPVYGVAARCPAGLTIDAPERLTVAGLYAQDQIRLTPQWTVLAGLRRDWST
NTIDDRIAREKTRQKDSATTLSAGVVYEFVPGWAAYASYGESFLPVSGTSFSGAPFVPETGKQWETGLKYEAPDRSVTGS
LALFDLKRSNVTTADPVNATFQVQTGTQRARGLELEVGAELQRHWKLTGAYTYTDSEVTRDNNAAIVGKPLNLTPRSTFA
LWATYQLPQMPQLTLGAGARHVTRQVGSYPFSLPAYTVVDLSVGYTGPSYRITAGVKNVFDRAYYDGAINANVVSPSLPR
NFSVGLTYFF
>Mature_730_residues
MIHLRPGAAFQRAAALALPRRPARSTLPALRLGRHALTPLALCLSQAAFAQSGTAVDGTAQSPAQLQEVRINAGTEKDVG
FAPTEAQTAGKMPMRRLETPQSVGVVTREQMESRQITNLQQALQTVAGVSPVNFGRRGVDDLNIRGFRSTESVLIDGLVQ
SVGMWTRLNPYGYERFEVLKGAASVLYGQVQPGGIVNAVSKRPRREALTEVGVEVGSFGQRTLQADLNRPLNESGKAAFR
INAQVANSDDPTDFIYRRDRWIAPSLSLDLGPQTDLVVFATYNQSQWMRQQGVTPYGTVLPNRNGPVRRTLYTGDPSFGG
YDIETKSLGYALEHRFSPALTLRQNVRYETEGGTGNLVANSTLQSNQRLQNRTATRQYMDDEMLATDTSVLAKFAALGVQ
HQLVAGLDARTGKSWLGRRTCSIAPMDLFNPVYGVAARCPAGLTIDAPERLTVAGLYAQDQIRLTPQWTVLAGLRRDWST
NTIDDRIAREKTRQKDSATTLSAGVVYEFVPGWAAYASYGESFLPVSGTSFSGAPFVPETGKQWETGLKYEAPDRSVTGS
LALFDLKRSNVTTADPVNATFQVQTGTQRARGLELEVGAELQRHWKLTGAYTYTDSEVTRDNNAAIVGKPLNLTPRSTFA
LWATYQLPQMPQLTLGAGARHVTRQVGSYPFSLPAYTVVDLSVGYTGPSYRITAGVKNVFDRAYYDGAINANVVSPSLPR
NFSVGLTYFF

Specific function: This receptor binds the ferrichrome-iron ligand. It interacts with the tonB protein, which is responsible for energy coupling of the ferrichrome-promoted iron transport system. Acts as a receptor for bacteriophage T5 as well as T1, phi80 and colicin M. Bi

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=740, Percent_Identity=30.4054054054054, Blast_Score=243, Evalue=3e-65,
Organism=Escherichia coli, GI1787344, Length=758, Percent_Identity=26.2532981530343, Blast_Score=165, Evalue=9e-42,
Organism=Escherichia coli, GI1787024, Length=768, Percent_Identity=23.4375, Blast_Score=132, Evalue=7e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 79728; Mature: 79728

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHLRPGAAFQRAAALALPRRPARSTLPALRLGRHALTPLALCLSQAAFAQSGTAVDGTA
CEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCC
QSPAQLQEVRINAGTEKDVGFAPTEAQTAGKMPMRRLETPQSVGVVTREQMESRQITNLQ
CCCHHHHHEEECCCCCCCCCCCCCCCHHCCCCCHHHCCCCHHCCHHHHHHHHHHHHHHHH
QALQTVAGVSPVNFGRRGVDDLNIRGFRSTESVLIDGLVQSVGMWTRLNPYGYERFEVLK
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEECCCCCCHHHHHHH
GAASVLYGQVQPGGIVNAVSKRPRREALTEVGVEVGSFGQRTLQADLNRPLNESGKAAFR
HHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHCCHHCCCCHHHHHHHCCCCCCCCCCEEEE
INAQVANSDDPTDFIYRRDRWIAPSLSLDLGPQTDLVVFATYNQSQWMRQQGVTPYGTVL
EEEEECCCCCCHHHHEECCCEECCCCEECCCCCCCEEEEEECCHHHHHHHCCCCCCCCCC
PNRNGPVRRTLYTGDPSFGGYDIETKSLGYALEHRFSPALTLRQNVRYETEGGTGNLVAN
CCCCCCEEEEEEECCCCCCCEEEEHHHHHHHHHHCCCCHHHHHHCCEEEECCCCCCEEEC
STLQSNQRLQNRTATRQYMDDEMLATDTSVLAKFAALGVQHQLVAGLDARTGKSWLGRRT
CHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHCHHHHHHHCCCCCCCHHHHCCCC
CSIAPMDLFNPVYGVAARCPAGLTIDAPERLTVAGLYAQDQIRLTPQWTVLAGLRRDWST
CCCCCHHHHCHHHHHHHHCCCCCEECCCCCEEEEEEEECCEEEECCCHHHHHHHHCCCCC
NTIDDRIAREKTRQKDSATTLSAGVVYEFVPGWAAYASYGESFLPVSGTSFSGAPFVPET
CCHHHHHHHHHHHCCCCCCEECCCCCEECCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCC
GKQWETGLKYEAPDRSVTGSLALFDLKRSNVTTADPVNATFQVQTGTQRARGLELEVGAE
CCHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEECCCHHHCCCEEEECHH
LQRHWKLTGAYTYTDSEVTRDNNAAIVGKPLNLTPRSTFALWATYQLPQMPQLTLGAGAR
HHHCEEEEEEEEECCCCCCCCCCCEEEECCCCCCCCCCEEEEEEECCCCCCCEECCCCHH
HVTRQVGSYPFSLPAYTVVDLSVGYTGPSYRITAGVKNVFDRAYYDGAINANVVSPSLPR
HHHHHHCCCCCCCCCEEEEEEEECCCCCCEEEEHHHHHHHHHHHCCCCCCCEEECCCCCC
NFSVGLTYFF
CCCCCEEEEC
>Mature Secondary Structure
MIHLRPGAAFQRAAALALPRRPARSTLPALRLGRHALTPLALCLSQAAFAQSGTAVDGTA
CEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCC
QSPAQLQEVRINAGTEKDVGFAPTEAQTAGKMPMRRLETPQSVGVVTREQMESRQITNLQ
CCCHHHHHEEECCCCCCCCCCCCCCCHHCCCCCHHHCCCCHHCCHHHHHHHHHHHHHHHH
QALQTVAGVSPVNFGRRGVDDLNIRGFRSTESVLIDGLVQSVGMWTRLNPYGYERFEVLK
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEECCCCCCHHHHHHH
GAASVLYGQVQPGGIVNAVSKRPRREALTEVGVEVGSFGQRTLQADLNRPLNESGKAAFR
HHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHCCHHCCCCHHHHHHHCCCCCCCCCCEEEE
INAQVANSDDPTDFIYRRDRWIAPSLSLDLGPQTDLVVFATYNQSQWMRQQGVTPYGTVL
EEEEECCCCCCHHHHEECCCEECCCCEECCCCCCCEEEEEECCHHHHHHHCCCCCCCCCC
PNRNGPVRRTLYTGDPSFGGYDIETKSLGYALEHRFSPALTLRQNVRYETEGGTGNLVAN
CCCCCCEEEEEEECCCCCCCEEEEHHHHHHHHHHCCCCHHHHHHCCEEEECCCCCCEEEC
STLQSNQRLQNRTATRQYMDDEMLATDTSVLAKFAALGVQHQLVAGLDARTGKSWLGRRT
CHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHCHHHHHHHCCCCCCCHHHHCCCC
CSIAPMDLFNPVYGVAARCPAGLTIDAPERLTVAGLYAQDQIRLTPQWTVLAGLRRDWST
CCCCCHHHHCHHHHHHHHCCCCCEECCCCCEEEEEEEECCEEEECCCHHHHHHHHCCCCC
NTIDDRIAREKTRQKDSATTLSAGVVYEFVPGWAAYASYGESFLPVSGTSFSGAPFVPET
CCHHHHHHHHHHHCCCCCCEECCCCCEECCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCC
GKQWETGLKYEAPDRSVTGSLALFDLKRSNVTTADPVNATFQVQTGTQRARGLELEVGAE
CCHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEECCCHHHCCCEEEECHH
LQRHWKLTGAYTYTDSEVTRDNNAAIVGKPLNLTPRSTFALWATYQLPQMPQLTLGAGAR
HHHCEEEEEEEEECCCCCCCCCCCEEEECCCCCCCCCCEEEEEEECCCCCCCEECCCCHH
HVTRQVGSYPFSLPAYTVVDLSVGYTGPSYRITAGVKNVFDRAYYDGAINANVVSPSLPR
HHHHHHCCCCCCCCCEEEEEEEECCCCCCEEEEHHHHHHHHHHHCCCCCCCEEECCCCCC
NFSVGLTYFF
CCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3079747; 8202364; 9278503; 2823072; 7515827; 8617231; 9856937; 9865695; 10850805 [H]