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The map label for this gene is ctaD [H]

Identifier: 120612545

GI number: 120612545

Start: 4328650

End: 4330293

Strand: Reverse

Name: ctaD [H]

Synonym: Aave_3906

Alternate gene names: 120612545

Gene position: 4330293-4328650 (Counterclockwise)

Preceding gene: 120612546

Following gene: 120612544

Centisome position: 80.9

GC content: 64.42

Gene sequence:

>1644_bases
ATGAGCGCAGTTCTCGACCCCACCGGGCATGCCGCCGGCCATGACCACGGCGGCCACGACCACGACCATGCACACCATGG
CCCGACCGGCTGGCGCCGCTGGGTGTTCGCCACCAACCACAAGGACATCGGCACGCTGTACCTGCTGTTCTCGTTCACCA
TGCTGATGATCGGCGGCATCCTGGCGCTGCTGATCCGCGCCGAGCTGTTCCAGCCCGGCCTGCAGATCGTGAACCCTGAG
CTCTTCAACCAGCTCACCACCATGCACGGTCTCATCATGGTGTTCGGGGCCATCATGCCGGCCTTCGTGGGCTTCGCGAA
CTGGATGATCCCGCTGCAGATCGGCGCATCCGACATGGCCTTCGCGCGCATGAACAACTTCAGCTTCTGGCTGATGATCC
CGGCCGCGCTGATGCTGGTCAGCTCGTTCTTCATGCCCGGCGGCGCCCCCGCCGCGGGCTGGACGCTCTACGCGCCGCTC
ACGCTGCAGATGGGCCCCTCCATGGATGCCGGCATCTTCGCCATGCACATCCTGGGCGCCTCGTCCATCATGGGCTCGAT
CAACATCATCGTGACCATCCTGAACATGCGCGCGCCGGGCATGACGCTCATGAAGATGCCCATGTTCTGCTGGACCTGGC
TCATCACCGCCTACCTGCTGATCGCCGTCATGCCCGTGCTGGCCGGCGCCATCACCATGACGCTGACCGACCGGCACTTC
GGCACCAGCTTCTTCAACCCGGCAGGCGGCGGCGACCCGGTGATGTACCAGCACATCTTCTGGTTCTTCGGCCACCCCGA
GGTGTACATCATGATCCTGCCGGCGTTCGGCATCATCAGCCAGATCGTGCCGGCCTTCAGCCGCAAGAAGCTCTTCGGCT
ACGCCTCCATGGTGTACGCCACCTCGTCCATCGCCATCCTGTCGTTCATCGTGTGGGCGCACCACATGTTCACCACGGGC
ATGCCGGTCACGGGCCAGCTGTTCTTCATGTACGCCACCATGCTGATCTCCGTGCCCACGGCCGTGAAGATCTTCAACTG
GATCGCCACCATGTGGCGCGGCTCCATGACCTTCGAGACGCCCATGCTGTTCGCCGTGGGCTTCATCTTCGTGTTCACCA
TGGGCGGCTTCACCGGCCTCATCCTGTCGATGGCGCCCATCGACATCCAGCTGCAGGACACCTACTACGTGGTGGCCCAC
TTCCACTACGTGCTGGTGGCCGGCTCGCTGTTCTCCATGTTCGCGGCCTACTACTACTGGGCCCCGAAATGGACGGGCGT
GATGTATTCGGAGCGCCGCGGCCAGATCCACTTCTGGGGCTCGCTCATCACCTTCAACATCACCTTCTTCCCGATGCACT
TCCTGGGGCTGGCCGGCATGCCGCGCCGCTATGCCGACTACCCCATGCAGTTCGCCGACTTCAACATGGTGGCCTCCATC
GGGGCCTTCGGTTTCGGGCTGATGCAGGTGTATTTCTTCCTCGCCGTCGTGCTGCCCGCCATGCGCGGCAAGGGCGAGCC
CGCACCGCAGCGCCCGTGGGAAGCGGCCGAGGGCCTGGAGTGGGAAGTGCCGTCGCCCGCGCCGTTCCACACCTACGAAA
CCCCGCCCAGGCTCGACGCATCCGCCACGCGCGTGATCGGCTGA

Upstream 100 bases:

>100_bases
GAAGAACGCCTGGTCCAACAAGACCGGCCAGATCGTCCAGCCCGCGGAAATCGTGGCCCAGCGCGGCAAGTGAGACAGCT
AAAGCATTGAGGAACCCGAC

Downstream 100 bases:

>100_bases
CGGCACCAGTCCAGACGGAGCACGCGCGACATGGCGACACCCGAGCAGAAGAAGGCCAACCTGCGCATGGCCATCATCCT
GGCGAGCATCGCGGTGGCCT

Product: cytochrome-c oxidase

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 547; Mature: 546

Protein sequence:

>547_residues
MSAVLDPTGHAAGHDHGGHDHDHAHHGPTGWRRWVFATNHKDIGTLYLLFSFTMLMIGGILALLIRAELFQPGLQIVNPE
LFNQLTTMHGLIMVFGAIMPAFVGFANWMIPLQIGASDMAFARMNNFSFWLMIPAALMLVSSFFMPGGAPAAGWTLYAPL
TLQMGPSMDAGIFAMHILGASSIMGSINIIVTILNMRAPGMTLMKMPMFCWTWLITAYLLIAVMPVLAGAITMTLTDRHF
GTSFFNPAGGGDPVMYQHIFWFFGHPEVYIMILPAFGIISQIVPAFSRKKLFGYASMVYATSSIAILSFIVWAHHMFTTG
MPVTGQLFFMYATMLISVPTAVKIFNWIATMWRGSMTFETPMLFAVGFIFVFTMGGFTGLILSMAPIDIQLQDTYYVVAH
FHYVLVAGSLFSMFAAYYYWAPKWTGVMYSERRGQIHFWGSLITFNITFFPMHFLGLAGMPRRYADYPMQFADFNMVASI
GAFGFGLMQVYFFLAVVLPAMRGKGEPAPQRPWEAAEGLEWEVPSPAPFHTYETPPRLDASATRVIG

Sequences:

>Translated_547_residues
MSAVLDPTGHAAGHDHGGHDHDHAHHGPTGWRRWVFATNHKDIGTLYLLFSFTMLMIGGILALLIRAELFQPGLQIVNPE
LFNQLTTMHGLIMVFGAIMPAFVGFANWMIPLQIGASDMAFARMNNFSFWLMIPAALMLVSSFFMPGGAPAAGWTLYAPL
TLQMGPSMDAGIFAMHILGASSIMGSINIIVTILNMRAPGMTLMKMPMFCWTWLITAYLLIAVMPVLAGAITMTLTDRHF
GTSFFNPAGGGDPVMYQHIFWFFGHPEVYIMILPAFGIISQIVPAFSRKKLFGYASMVYATSSIAILSFIVWAHHMFTTG
MPVTGQLFFMYATMLISVPTAVKIFNWIATMWRGSMTFETPMLFAVGFIFVFTMGGFTGLILSMAPIDIQLQDTYYVVAH
FHYVLVAGSLFSMFAAYYYWAPKWTGVMYSERRGQIHFWGSLITFNITFFPMHFLGLAGMPRRYADYPMQFADFNMVASI
GAFGFGLMQVYFFLAVVLPAMRGKGEPAPQRPWEAAEGLEWEVPSPAPFHTYETPPRLDASATRVIG
>Mature_546_residues
SAVLDPTGHAAGHDHGGHDHDHAHHGPTGWRRWVFATNHKDIGTLYLLFSFTMLMIGGILALLIRAELFQPGLQIVNPEL
FNQLTTMHGLIMVFGAIMPAFVGFANWMIPLQIGASDMAFARMNNFSFWLMIPAALMLVSSFFMPGGAPAAGWTLYAPLT
LQMGPSMDAGIFAMHILGASSIMGSINIIVTILNMRAPGMTLMKMPMFCWTWLITAYLLIAVMPVLAGAITMTLTDRHFG
TSFFNPAGGGDPVMYQHIFWFFGHPEVYIMILPAFGIISQIVPAFSRKKLFGYASMVYATSSIAILSFIVWAHHMFTTGM
PVTGQLFFMYATMLISVPTAVKIFNWIATMWRGSMTFETPMLFAVGFIFVFTMGGFTGLILSMAPIDIQLQDTYYVVAHF
HYVLVAGSLFSMFAAYYYWAPKWTGVMYSERRGQIHFWGSLITFNITFFPMHFLGLAGMPRRYADYPMQFADFNMVASIG
AFGFGLMQVYFFLAVVLPAMRGKGEPAPQRPWEAAEGLEWEVPSPAPFHTYETPPRLDASATRVIG

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=514, Percent_Identity=49.8054474708171, Blast_Score=468, Evalue=1e-132,
Organism=Escherichia coli, GI1786634, Length=517, Percent_Identity=38.8781431334623, Blast_Score=359, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6226519, Length=530, Percent_Identity=46.0377358490566, Blast_Score=474, Evalue=1e-134,
Organism=Saccharomyces cerevisiae, GI6226524, Length=323, Percent_Identity=49.2260061919505, Blast_Score=315, Evalue=1e-86,
Organism=Saccharomyces cerevisiae, GI6226523, Length=248, Percent_Identity=45.9677419354839, Blast_Score=206, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 60895; Mature: 60764

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
7.9 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
7.7 %Met     (Mature Protein)
7.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVLDPTGHAAGHDHGGHDHDHAHHGPTGWRRWVFATNHKDIGTLYLLFSFTMLMIGGI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHH
LALLIRAELFQPGLQIVNPELFNQLTTMHGLIMVFGAIMPAFVGFANWMIPLQIGASDMA
HHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCHHH
FARMNNFSFWLMIPAALMLVSSFFMPGGAPAAGWTLYAPLTLQMGPSMDAGIFAMHILGA
HHHHCCCEEHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHH
SSIMGSINIIVTILNMRAPGMTLMKMPMFCWTWLITAYLLIAVMPVLAGAITMTLTDRHF
HHHHHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCC
GTSFFNPAGGGDPVMYQHIFWFFGHPEVYIMILPAFGIISQIVPAFSRKKLFGYASMVYA
CCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHH
TSSIAILSFIVWAHHMFTTGMPVTGQLFFMYATMLISVPTAVKIFNWIATMWRGSMTFET
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
PMLFAVGFIFVFTMGGFTGLILSMAPIDIQLQDTYYVVAHFHYVLVAGSLFSMFAAYYYW
HHHHHHHHHHHHHHCCHHHHHHHHCCCEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHC
APKWTGVMYSERRGQIHFWGSLITFNITFFPMHFLGLAGMPRRYADYPMQFADFNMVASI
CCCCCCEEECCCCCCEEEEEEEEEEEEHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHH
GAFGFGLMQVYFFLAVVLPAMRGKGEPAPQRPWEAAEGLEWEVPSPAPFHTYETPPRLDA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCC
SATRVIG
CCCCCCC
>Mature Secondary Structure 
SAVLDPTGHAAGHDHGGHDHDHAHHGPTGWRRWVFATNHKDIGTLYLLFSFTMLMIGGI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHH
LALLIRAELFQPGLQIVNPELFNQLTTMHGLIMVFGAIMPAFVGFANWMIPLQIGASDMA
HHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCHHH
FARMNNFSFWLMIPAALMLVSSFFMPGGAPAAGWTLYAPLTLQMGPSMDAGIFAMHILGA
HHHHCCCEEHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHH
SSIMGSINIIVTILNMRAPGMTLMKMPMFCWTWLITAYLLIAVMPVLAGAITMTLTDRHF
HHHHHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCC
GTSFFNPAGGGDPVMYQHIFWFFGHPEVYIMILPAFGIISQIVPAFSRKKLFGYASMVYA
CCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHH
TSSIAILSFIVWAHHMFTTGMPVTGQLFFMYATMLISVPTAVKIFNWIATMWRGSMTFET
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
PMLFAVGFIFVFTMGGFTGLILSMAPIDIQLQDTYYVVAHFHYVLVAGSLFSMFAAYYYW
HHHHHHHHHHHHHHCCHHHHHHHHCCCEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHC
APKWTGVMYSERRGQIHFWGSLITFNITFFPMHFLGLAGMPRRYADYPMQFADFNMVASI
CCCCCCEEECCCCCCEEEEEEEEEEEEHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHH
GAFGFGLMQVYFFLAVVLPAMRGKGEPAPQRPWEAAEGLEWEVPSPAPFHTYETPPRLDA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCC
SATRVIG
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]