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The map label for this gene is aatB [H]

Identifier: 120612528

GI number: 120612528

Start: 4311724

End: 4312944

Strand: Reverse

Name: aatB [H]

Synonym: Aave_3888

Alternate gene names: 120612528

Gene position: 4312944-4311724 (Counterclockwise)

Preceding gene: 120612529

Following gene: 120612527

Centisome position: 80.57

GC content: 68.96

Gene sequence:

>1221_bases
ATGACTGATACCCAACCACACCCTTTCCTCGCCCGGCGCGTCCTGGGCGCCAAGCCTTCGGCCACCAAAGAAATGACGCG
GCTGGCCAACCAGCTCCGACGCGAGGGCCGCAGCGTCATCGCCCTCAGCCAGGGCGAGCCCGACTTCCCGACGCCGGCGC
ACGTGCGCGAGGCGGCCAAACAGGCCATCGACCGCAACGAGTCGCGCTACACGGACGTCGCCGGCACCTTCGCCCTGCGC
GAAGCGGTGGTCCGCAAGTTCGAGCGCGACAACGGCCTGAGGTACACGCCCGAGCAGGTCCAGGTCGGATGCGGCGCCAA
GCAGATCCTGTACAACGCGCTGCAGGCGACCCTCGACCCGGGCGACGAGGTCGTCGTGCCGACGCCCGCCTGGGTGTCGT
ATCCGGAAATGGTGCTGCTGGCAGGCGGGCAGCCCGTCATCGTGCGCTGCGGTGCGCGCAGCGGCTTCAAGATCACGCCG
GAGCAGCTGGATGCCGCGATCACGCCGCGCACCAAGTGGGTGATGCTGAATTCGCCGTCCAATCCCAGCGGTGCGGTGTA
CTCGCACGAAGAGCTCGCGGCGCTCGGCGAGGTGCTGCTCAGGCACCCGCAGGTCTGGATGATGGCGGACGACATCTACG
AGAAGATCCGCTACGACGACACGCCCTTCGCCACGCCTGCCGCCGTGACGCCCGCGCTGGCATCGCGCACGCTGACCATC
AACGGCGTATCCAAGGCCTATGCCATGACGGGCTGGCGCGTCGGCTTCGGTGCGGGGCCGCTCGAGCTGATCAAGGCGAT
GAACCTCGTGCAGTCCCAGTCGACCTCGCACACCAGTTCGATCAGCCAGGCGGCGTCCGTCGCGGCACTCGACGGCCCGA
TGGACTTCCTGCCGGCCTTCGTCGATGCATTCCGGCGGCGCCGCGATGCGGTGGTGGCCCGGCTCAACGCCATGGAGGGC
GTGTCGTGCGAACTGCCGCCAGGCGCGTTCTATGCCTTCCCCGGCGTGCAGGGGCTGCTGGGGCGCCGCGACCGGTCGGG
CCACCTCATCGCGACCGATGCCGACCTGGCGATGTACCTGCTGCGCGAAGCGGGCGTGGCCATCGTGCCCGGCTCTGCGT
TCGAACTGCCGGGCCATCTGCGCTTCTCCTATGCAGCGTCCGACGAGGACCTGTCGGAGGCGTTGAGCCGTGTGGCTGCC
GCATGCGCCGAACTGCACTGA

Upstream 100 bases:

>100_bases
CATGCGCGTACAGCCTCGTGCTGCTGCTGACGATCTTCGTGCCGCTCGGGCTGGCGCGCTGGCTCTTCCGGCTCAAGGTC
GGAACTCTTGATTGAACCCC

Downstream 100 bases:

>100_bases
ATTCTTCTTCCAAGGGCCCACCAATGACCAAGAACCAGACCCTCCGCGCGGCGCTGGGCAGCGGCACGCTGTTCACCGCC
ATGGCGGCACACAACCCCCT

Product: aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MTDTQPHPFLARRVLGAKPSATKEMTRLANQLRREGRSVIALSQGEPDFPTPAHVREAAKQAIDRNESRYTDVAGTFALR
EAVVRKFERDNGLRYTPEQVQVGCGAKQILYNALQATLDPGDEVVVPTPAWVSYPEMVLLAGGQPVIVRCGARSGFKITP
EQLDAAITPRTKWVMLNSPSNPSGAVYSHEELAALGEVLLRHPQVWMMADDIYEKIRYDDTPFATPAAVTPALASRTLTI
NGVSKAYAMTGWRVGFGAGPLELIKAMNLVQSQSTSHTSSISQAASVAALDGPMDFLPAFVDAFRRRRDAVVARLNAMEG
VSCELPPGAFYAFPGVQGLLGRRDRSGHLIATDADLAMYLLREAGVAIVPGSAFELPGHLRFSYAASDEDLSEALSRVAA
ACAELH

Sequences:

>Translated_406_residues
MTDTQPHPFLARRVLGAKPSATKEMTRLANQLRREGRSVIALSQGEPDFPTPAHVREAAKQAIDRNESRYTDVAGTFALR
EAVVRKFERDNGLRYTPEQVQVGCGAKQILYNALQATLDPGDEVVVPTPAWVSYPEMVLLAGGQPVIVRCGARSGFKITP
EQLDAAITPRTKWVMLNSPSNPSGAVYSHEELAALGEVLLRHPQVWMMADDIYEKIRYDDTPFATPAAVTPALASRTLTI
NGVSKAYAMTGWRVGFGAGPLELIKAMNLVQSQSTSHTSSISQAASVAALDGPMDFLPAFVDAFRRRRDAVVARLNAMEG
VSCELPPGAFYAFPGVQGLLGRRDRSGHLIATDADLAMYLLREAGVAIVPGSAFELPGHLRFSYAASDEDLSEALSRVAA
ACAELH
>Mature_405_residues
TDTQPHPFLARRVLGAKPSATKEMTRLANQLRREGRSVIALSQGEPDFPTPAHVREAAKQAIDRNESRYTDVAGTFALRE
AVVRKFERDNGLRYTPEQVQVGCGAKQILYNALQATLDPGDEVVVPTPAWVSYPEMVLLAGGQPVIVRCGARSGFKITPE
QLDAAITPRTKWVMLNSPSNPSGAVYSHEELAALGEVLLRHPQVWMMADDIYEKIRYDDTPFATPAAVTPALASRTLTIN
GVSKAYAMTGWRVGFGAGPLELIKAMNLVQSQSTSHTSSISQAASVAALDGPMDFLPAFVDAFRRRRDAVVARLNAMEGV
SCELPPGAFYAFPGVQGLLGRRDRSGHLIATDADLAMYLLREAGVAIVPGSAFELPGHLRFSYAASDEDLSEALSRVAAA
CAELH

Specific function: Involved in symbiotic nitrogen fixation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=424, Percent_Identity=27.8301886792453, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI169881279, Length=424, Percent_Identity=27.8301886792453, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI56713256, Length=417, Percent_Identity=26.6187050359712, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI56713254, Length=417, Percent_Identity=26.6187050359712, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI169881281, Length=421, Percent_Identity=24.9406175771971, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI4507369, Length=396, Percent_Identity=24.4949494949495, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI1786816, Length=385, Percent_Identity=29.6103896103896, Blast_Score=154, Evalue=7e-39,
Organism=Escherichia coli, GI1788627, Length=397, Percent_Identity=28.7153652392947, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1788722, Length=405, Percent_Identity=27.1604938271605, Blast_Score=124, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71994472, Length=424, Percent_Identity=27.3584905660377, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71994476, Length=419, Percent_Identity=27.2076372315036, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17567369, Length=360, Percent_Identity=25.8333333333333, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17567663, Length=379, Percent_Identity=24.5382585751979, Blast_Score=108, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6322401, Length=401, Percent_Identity=24.9376558603491, Blast_Score=129, Evalue=7e-31,
Organism=Drosophila melanogaster, GI28573069, Length=412, Percent_Identity=25.9708737864078, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24646114, Length=412, Percent_Identity=25.9708737864078, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI28573067, Length=412, Percent_Identity=25.9708737864078, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI28573065, Length=412, Percent_Identity=25.9708737864078, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI18859735, Length=392, Percent_Identity=24.7448979591837, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI45551451, Length=401, Percent_Identity=24.6882793017456, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24641770, Length=401, Percent_Identity=24.6882793017456, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641760, Length=401, Percent_Identity=24.6882793017456, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641768, Length=401, Percent_Identity=24.6882793017456, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641766, Length=401, Percent_Identity=24.6882793017456, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641764, Length=401, Percent_Identity=24.6882793017456, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43887; Mature: 43756

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTQPHPFLARRVLGAKPSATKEMTRLANQLRREGRSVIALSQGEPDFPTPAHVREAAK
CCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHH
QAIDRNESRYTDVAGTFALREAVVRKFERDNGLRYTPEQVQVGCGAKQILYNALQATLDP
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEECCCHHHHHHHHHHHHCCC
GDEVVVPTPAWVSYPEMVLLAGGQPVIVRCGARSGFKITPEQLDAAITPRTKWVMLNSPS
CCCEEECCCCCCCCCCEEEEECCCEEEEEECCCCCCEECHHHHCCEECCCEEEEEEECCC
NPSGAVYSHEELAALGEVLLRHPQVWMMADDIYEKIRYDDTPFATPAAVTPALASRTLTI
CCCCCEECHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCCCCCCCHHHHHHHHCCEEEE
NGVSKAYAMTGWRVGFGAGPLELIKAMNLVQSQSTSHTSSISQAASVAALDGPMDFLPAF
ECCHHHHHHCCEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHH
VDAFRRRRDAVVARLNAMEGVSCELPPGAFYAFPGVQGLLGRRDRSGHLIATDADLAMYL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCHHHHHCCCCCCCCEEEECHHHHHHH
LREAGVAIVPGSAFELPGHLRFSYAASDEDLSEALSRVAAACAELH
HHHCCEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDTQPHPFLARRVLGAKPSATKEMTRLANQLRREGRSVIALSQGEPDFPTPAHVREAAK
CCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHH
QAIDRNESRYTDVAGTFALREAVVRKFERDNGLRYTPEQVQVGCGAKQILYNALQATLDP
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEECCCHHHHHHHHHHHHCCC
GDEVVVPTPAWVSYPEMVLLAGGQPVIVRCGARSGFKITPEQLDAAITPRTKWVMLNSPS
CCCEEECCCCCCCCCCEEEEECCCEEEEEECCCCCCEECHHHHCCEECCCEEEEEEECCC
NPSGAVYSHEELAALGEVLLRHPQVWMMADDIYEKIRYDDTPFATPAAVTPALASRTLTI
CCCCCEECHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCCCCCCCHHHHHHHHCCEEEE
NGVSKAYAMTGWRVGFGAGPLELIKAMNLVQSQSTSHTSSISQAASVAALDGPMDFLPAF
ECCHHHHHHCCEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHH
VDAFRRRRDAVVARLNAMEGVSCELPPGAFYAFPGVQGLLGRRDRSGHLIATDADLAMYL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCHHHHHCCCCCCCCEEEECHHHHHHH
LREAGVAIVPGSAFELPGHLRFSYAASDEDLSEALSRVAAACAELH
HHHCCEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]