Click here to switch to the map view.

The map label for this gene is ispH [H]

Identifier: 120612414

GI number: 120612414

Start: 4191702

End: 4192700

Strand: Reverse

Name: ispH [H]

Synonym: Aave_3771

Alternate gene names: 120612414

Gene position: 4192700-4191702 (Counterclockwise)

Preceding gene: 120612415

Following gene: 120612413

Centisome position: 78.33

GC content: 68.77

Gene sequence:

>999_bases
ATGGCCATCCAACCCCAGGAAATCGTTCTCGCCGAGCCCCGCGGCTTCTGCGCGGGCGTGGACCGCGCGATCGAGATCGT
CGAGCGGGCCCTGCAGAAGTTCGGCGCGCCGATCTACGTGCGCCACGAAATCGTGCACAACACCTACGTGGTGAACGACC
TGAAGGCCAAGGGCGCGATCTTCATCGAGGACCTGGCCGATGTGCCGCCGGGCGCCACCCTGGTGTTCAGCGCGCACGGC
GTCAGCAAGGCGGTGCAGGCCGAGGCCGAGGCGCGGGGGTTCAGCATCTTCGATGCGACCTGTCCCCTGGTCACGAAGGT
GCATGTGGAGGTGGCCAAGCTCGCGAAGGAAGGCTACGAATTCATCATGATCGGCCACAAGGGCCATCCGGAGGTCGAGG
GCACCATGGGGCAACTGGACCACGGCATCCACCTCGTGGAAGACGTGGAGGACGTGGCCCGCGTGCAGCCGTCGCAGACC
GCGAAACTGGCCGTGGTCACGCAGACCACGCTGTCGGTGGACGACGCGGCCGAGATCACCGCCGCCGTGCGCGCGCGCTT
CCCGCAGGTGCGCGAACCCAAGCAGCAGGACATCTGCTATGCCACCCAGAACCGCCAGGACGCGGTGAAGGTGCTGTCCG
GGCAGGTGGATCTCGTCATCGTGGTGGGCAGCCCCACCAGCTCCAACAGCAACCGGCTGCGCGAACTGGCGGTGCGGCTG
GGCACGCCCTCCTACATGGTGGACAGTGCCGACGAGCTGCGGCCGGAGTGGTTCGATGGCGCCGCCCGCGTCGGCCTCAC
GGCGGGCGCGTCGGCCCCCGAGGTGCTGGTGCGGCAGGTGATCGAACGCATACGGGCGCTGGGCGCGGTGTCGCTGCGCC
GGATGGACGGCATCGAGGAGACGGTGAAGTTCCCGCTGCCCAAGGGCCTGAAGATCGACGCGGCCACCGGCCTGGAAATC
TCCCAGCGCACGCCCGAGACGGGGGCGGGGCGGTCCTGA

Upstream 100 bases:

>100_bases
GAGGTGCGGGGGGACGGCGCCGTGCGCTTCGACTTCAACCATCCGCTCGCGGGCCAGCCCGTCGTCTTCGAGGTGCAACT
CATCGGAGTGCTCTGACGCC

Downstream 100 bases:

>100_bases
GCCGCATCCGCACGGCCCGTTCCGTGGCGCGAGCACGCCACGGCCGGGCCAAATCCCTACGCAGCCGGGCATTGAATCCC
CCCATCGCGGGTAGGACTTC

Product: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MAIQPQEIVLAEPRGFCAGVDRAIEIVERALQKFGAPIYVRHEIVHNTYVVNDLKAKGAIFIEDLADVPPGATLVFSAHG
VSKAVQAEAEARGFSIFDATCPLVTKVHVEVAKLAKEGYEFIMIGHKGHPEVEGTMGQLDHGIHLVEDVEDVARVQPSQT
AKLAVVTQTTLSVDDAAEITAAVRARFPQVREPKQQDICYATQNRQDAVKVLSGQVDLVIVVGSPTSSNSNRLRELAVRL
GTPSYMVDSADELRPEWFDGAARVGLTAGASAPEVLVRQVIERIRALGAVSLRRMDGIEETVKFPLPKGLKIDAATGLEI
SQRTPETGAGRS

Sequences:

>Translated_332_residues
MAIQPQEIVLAEPRGFCAGVDRAIEIVERALQKFGAPIYVRHEIVHNTYVVNDLKAKGAIFIEDLADVPPGATLVFSAHG
VSKAVQAEAEARGFSIFDATCPLVTKVHVEVAKLAKEGYEFIMIGHKGHPEVEGTMGQLDHGIHLVEDVEDVARVQPSQT
AKLAVVTQTTLSVDDAAEITAAVRARFPQVREPKQQDICYATQNRQDAVKVLSGQVDLVIVVGSPTSSNSNRLRELAVRL
GTPSYMVDSADELRPEWFDGAARVGLTAGASAPEVLVRQVIERIRALGAVSLRRMDGIEETVKFPLPKGLKIDAATGLEI
SQRTPETGAGRS
>Mature_331_residues
AIQPQEIVLAEPRGFCAGVDRAIEIVERALQKFGAPIYVRHEIVHNTYVVNDLKAKGAIFIEDLADVPPGATLVFSAHGV
SKAVQAEAEARGFSIFDATCPLVTKVHVEVAKLAKEGYEFIMIGHKGHPEVEGTMGQLDHGIHLVEDVEDVARVQPSQTA
KLAVVTQTTLSVDDAAEITAAVRARFPQVREPKQQDICYATQNRQDAVKVLSGQVDLVIVVGSPTSSNSNRLRELAVRLG
TPSYMVDSADELRPEWFDGAARVGLTAGASAPEVLVRQVIERIRALGAVSLRRMDGIEETVKFPLPKGLKIDAATGLEIS
QRTPETGAGRS

Specific function: Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) [H]

COG id: COG0761

COG function: function code IM; Penicillin tolerance protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispH family [H]

Homologues:

Organism=Escherichia coli, GI1786212, Length=310, Percent_Identity=55.1612903225806, Blast_Score=360, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003451 [H]

Pfam domain/function: PF02401 LYTB [H]

EC number: =1.17.1.2 [H]

Molecular weight: Translated: 35813; Mature: 35682

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIQPQEIVLAEPRGFCAGVDRAIEIVERALQKFGAPIYVRHEIVHNTYVVNDLKAKGAI
CCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHCEEEEECCCCCCCE
FIEDLADVPPGATLVFSAHGVSKAVQAEAEARGFSIFDATCPLVTKVHVEVAKLAKEGYE
EEEHHHCCCCCCEEEEECCCHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHCCCE
FIMIGHKGHPEVEGTMGQLDHGIHLVEDVEDVARVQPSQTAKLAVVTQTTLSVDDAAEIT
EEEECCCCCCCCCCCHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCHHHHHH
AAVRARFPQVREPKQQDICYATQNRQDAVKVLSGQVDLVIVVGSPTSSNSNRLRELAVRL
HHHHHHCCCCCCCCHHCCEEECCCHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHC
GTPSYMVDSADELRPEWFDGAARVGLTAGASAPEVLVRQVIERIRALGAVSLRRMDGIEE
CCCCCEECCHHHCCCHHHCCHHHCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHH
TVKFPLPKGLKIDAATGLEISQRTPETGAGRS
HHHCCCCCCCEEECCCCCEECCCCCCCCCCCC
>Mature Secondary Structure 
AIQPQEIVLAEPRGFCAGVDRAIEIVERALQKFGAPIYVRHEIVHNTYVVNDLKAKGAI
CCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHCEEEEECCCCCCCE
FIEDLADVPPGATLVFSAHGVSKAVQAEAEARGFSIFDATCPLVTKVHVEVAKLAKEGYE
EEEHHHCCCCCCEEEEECCCHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHCCCE
FIMIGHKGHPEVEGTMGQLDHGIHLVEDVEDVARVQPSQTAKLAVVTQTTLSVDDAAEIT
EEEECCCCCCCCCCCHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCHHHHHH
AAVRARFPQVREPKQQDICYATQNRQDAVKVLSGQVDLVIVVGSPTSSNSNRLRELAVRL
HHHHHHCCCCCCCCHHCCEEECCCHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHC
GTPSYMVDSADELRPEWFDGAARVGLTAGASAPEVLVRQVIERIRALGAVSLRRMDGIEE
CCCCCEECCHHHCCCHHHCCHHHCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHH
TVKFPLPKGLKIDAATGLEISQRTPETGAGRS
HHHCCCCCCCEEECCCCCEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA