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The map label for this gene is ytfL [C]

Identifier: 120612413

GI number: 120612413

Start: 4190228

End: 4191553

Strand: Reverse

Name: ytfL [C]

Synonym: Aave_3770

Alternate gene names: 120612413

Gene position: 4191553-4190228 (Counterclockwise)

Preceding gene: 120612414

Following gene: 120612411

Centisome position: 78.31

GC content: 67.35

Gene sequence:

>1326_bases
ATGGAAATAGCAATACTTTTCGCCCTCATCCTTCTCAATGGCCTTTTTGCCATGTCCGAGCTGGCGCTGGTTTCCGCGCG
CAAGACCCGGTTGCAGAAGCTGATCGATGAGGGCGATACCGGCGCCATCGCCGCCATGAAGCTCGGCGAAGACCCTACGC
GCTTTCTCTCCACCATCCAGATCGGCATCACCTCGATCGGCGTGCTCAACGGCATTGTCGGCGAGGCCGCACTCGCCGCG
CCGCTGGGCGAGTGGCTGCTGTCGTTGGGCATGCCCGAGAAGGCCGCCGGCTACACGGCGACGGGCCTGGTGGTGGTCTT
CATCACCTATTTCTCCATCGTCGTGGGCGAACTGGTGCCCAAGCGCCTGGGCCAGAGCTATCCCGAGACGCTGGCGCGCC
TGGTGGCCCGCCCCATCAACTGGCTGGCGCTCGCCACCAAGCCGTTCGTGCGGCTGCTGTCGGTGTCCACCCAGGCCCTG
CTGCGGCTGCTGGGCGTGAAGGAGAACACCGCCAGCGCCGTGACCGAGGCCGAGATCCATGCCGTGCTGGCCGAGGGCAC
GAGCGCGGGCGTGATCGAATCCCACGAGCACCAGATGGTGCGCAACGTGTTCCGCCTGGACGACCGCCAGATCGGCTCCC
TCATGGTGCCGCGCGCCGACGTGGTGGTGCTCGACGTGGAGGATTCCTTCGAGGAGAACCTGCAGCGCGTCGAGGCCTCC
GACCACGGCCGCTTCCCGGTGGTGCGCGGCGGCATGGAGAACGTGCTGGGCGTGCTCAACGCCCGCCAGTGGCTGTCGCG
CTCGCTGCGCGAGGACGTGCGCGACCTGGCCACCCAGCCGCTGCAGTCGGCCCTGTACGTGCCCGAGACCATCACCGGCA
TGGAGCTGCTCGACAACTTCCGCCAGTCCGACCTGCAGATGGCCTTCGTGATCGACGAATACGGCGAGGTGCAGGGCATC
GTCACGCTGCGCGACCTCATCGAGGCGATCACCGGCGAATTCCACGCGCGCGATCCGGAAACCTCCTGGGCCGTGCAGCG
CGAGGACGGCAGCTGGCTGCTCGACGGCCACATTCCCGTGCCGGAACTCAAGGACCGCCTGGGCCTGGACACCGTGCCCG
AGGAAGAGCGCGGCCGCTACCACACGCTCAGCGGCATGGTGATGCTGCTGACCGGCAAGCTGCCCAAGGTGACCGACACC
GTGCAGTGGGAGGAGTGGCAGTTCGAGGTGGTGGACATGGACGGCAAGACCATCGACAAGGTGCTCGCCAGCCCGCTGCC
CTCGGTCGAGATCGCGCAGCCGCAGGGCGCGGCGATGGCCGACTGA

Upstream 100 bases:

>100_bases
CCAAATCCCTACGCAGCCGGGCATTGAATCCCCCCATCGCGGGTAGGACTTCTTACAATTTGAGTCCGATTCACTCCGAG
GGAGCCTTCACTCCCTGTCT

Downstream 100 bases:

>100_bases
GCCTTCAGCTCCAGAGGTCGAGCGGCGGGTCCGCCGCCACCGCGCGCAGGATGTCGGTGCGCGAGATGAAGCCGGCGAGC
GTGCCGTATTCGTCCGTCAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MEIAILFALILLNGLFAMSELALVSARKTRLQKLIDEGDTGAIAAMKLGEDPTRFLSTIQIGITSIGVLNGIVGEAALAA
PLGEWLLSLGMPEKAAGYTATGLVVVFITYFSIVVGELVPKRLGQSYPETLARLVARPINWLALATKPFVRLLSVSTQAL
LRLLGVKENTASAVTEAEIHAVLAEGTSAGVIESHEHQMVRNVFRLDDRQIGSLMVPRADVVVLDVEDSFEENLQRVEAS
DHGRFPVVRGGMENVLGVLNARQWLSRSLREDVRDLATQPLQSALYVPETITGMELLDNFRQSDLQMAFVIDEYGEVQGI
VTLRDLIEAITGEFHARDPETSWAVQREDGSWLLDGHIPVPELKDRLGLDTVPEEERGRYHTLSGMVMLLTGKLPKVTDT
VQWEEWQFEVVDMDGKTIDKVLASPLPSVEIAQPQGAAMAD

Sequences:

>Translated_441_residues
MEIAILFALILLNGLFAMSELALVSARKTRLQKLIDEGDTGAIAAMKLGEDPTRFLSTIQIGITSIGVLNGIVGEAALAA
PLGEWLLSLGMPEKAAGYTATGLVVVFITYFSIVVGELVPKRLGQSYPETLARLVARPINWLALATKPFVRLLSVSTQAL
LRLLGVKENTASAVTEAEIHAVLAEGTSAGVIESHEHQMVRNVFRLDDRQIGSLMVPRADVVVLDVEDSFEENLQRVEAS
DHGRFPVVRGGMENVLGVLNARQWLSRSLREDVRDLATQPLQSALYVPETITGMELLDNFRQSDLQMAFVIDEYGEVQGI
VTLRDLIEAITGEFHARDPETSWAVQREDGSWLLDGHIPVPELKDRLGLDTVPEEERGRYHTLSGMVMLLTGKLPKVTDT
VQWEEWQFEVVDMDGKTIDKVLASPLPSVEIAQPQGAAMAD
>Mature_441_residues
MEIAILFALILLNGLFAMSELALVSARKTRLQKLIDEGDTGAIAAMKLGEDPTRFLSTIQIGITSIGVLNGIVGEAALAA
PLGEWLLSLGMPEKAAGYTATGLVVVFITYFSIVVGELVPKRLGQSYPETLARLVARPINWLALATKPFVRLLSVSTQAL
LRLLGVKENTASAVTEAEIHAVLAEGTSAGVIESHEHQMVRNVFRLDDRQIGSLMVPRADVVVLDVEDSFEENLQRVEAS
DHGRFPVVRGGMENVLGVLNARQWLSRSLREDVRDLATQPLQSALYVPETITGMELLDNFRQSDLQMAFVIDEYGEVQGI
VTLRDLIEAITGEFHARDPETSWAVQREDGSWLLDGHIPVPELKDRLGLDTVPEEERGRYHTLSGMVMLLTGKLPKVTDT
VQWEEWQFEVVDMDGKTIDKVLASPLPSVEIAQPQGAAMAD

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=371, Percent_Identity=27.2237196765499, Blast_Score=153, Evalue=3e-37,
Organism=Escherichia coli, GI1790664, Length=427, Percent_Identity=30.2107728337237, Blast_Score=235, Evalue=4e-63,
Organism=Escherichia coli, GI145693175, Length=417, Percent_Identity=25.1798561151079, Blast_Score=138, Evalue=8e-34,
Organism=Escherichia coli, GI87082033, Length=387, Percent_Identity=28.6821705426357, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1788119, Length=373, Percent_Identity=26.2734584450402, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1786879, Length=261, Percent_Identity=27.2030651340996, Blast_Score=92, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 48355; Mature: 48355

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIAILFALILLNGLFAMSELALVSARKTRLQKLIDEGDTGAIAAMKLGEDPTRFLSTIQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHH
IGITSIGVLNGIVGEAALAAPLGEWLLSLGMPEKAAGYTATGLVVVFITYFSIVVGELVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHH
KRLGQSYPETLARLVARPINWLALATKPFVRLLSVSTQALLRLLGVKENTASAVTEAEIH
HHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
AVLAEGTSAGVIESHEHQMVRNVFRLDDRQIGSLMVPRADVVVLDVEDSFEENLQRVEAS
HHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHCCEECCCCCEEEEECCHHHHHHHHHHCCC
DHGRFPVVRGGMENVLGVLNARQWLSRSLREDVRDLATQPLQSALYVPETITGMELLDNF
CCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
RQSDLQMAFVIDEYGEVQGIVTLRDLIEAITGEFHARDPETSWAVQREDGSWLLDGHIPV
HHHCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCEEEECCCCC
PELKDRLGLDTVPEEERGRYHTLSGMVMLLTGKLPKVTDTVQWEEWQFEVVDMDGKTIDK
HHHHHHCCCCCCCCHHCCCEEEHHCCCEEEECCCCCCCCCCEECCEEEEEEECCCHHHHH
VLASPLPSVEIAQPQGAAMAD
HHHCCCCCCEECCCCCCCCCC
>Mature Secondary Structure
MEIAILFALILLNGLFAMSELALVSARKTRLQKLIDEGDTGAIAAMKLGEDPTRFLSTIQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHH
IGITSIGVLNGIVGEAALAAPLGEWLLSLGMPEKAAGYTATGLVVVFITYFSIVVGELVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHH
KRLGQSYPETLARLVARPINWLALATKPFVRLLSVSTQALLRLLGVKENTASAVTEAEIH
HHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
AVLAEGTSAGVIESHEHQMVRNVFRLDDRQIGSLMVPRADVVVLDVEDSFEENLQRVEAS
HHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHCCEECCCCCEEEEECCHHHHHHHHHHCCC
DHGRFPVVRGGMENVLGVLNARQWLSRSLREDVRDLATQPLQSALYVPETITGMELLDNF
CCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
RQSDLQMAFVIDEYGEVQGIVTLRDLIEAITGEFHARDPETSWAVQREDGSWLLDGHIPV
HHHCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCEEEECCCCC
PELKDRLGLDTVPEEERGRYHTLSGMVMLLTGKLPKVTDTVQWEEWQFEVVDMDGKTIDK
HHHHHHCCCCCCCCHHCCCEEEHHCCCEEEECCCCCCCCCCEECCEEEEEEECCCHHHHH
VLASPLPSVEIAQPQGAAMAD
HHHCCCCCCEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]