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The map label for this gene is syrD [H]

Identifier: 120612367

GI number: 120612367

Start: 4111086

End: 4112780

Strand: Reverse

Name: syrD [H]

Synonym: Aave_3724

Alternate gene names: 120612367

Gene position: 4112780-4111086 (Counterclockwise)

Preceding gene: 120612372

Following gene: 120612366

Centisome position: 76.83

GC content: 70.74

Gene sequence:

>1695_bases
ATGACTGCAGCCCCCGCTCCGCGTGCCCCGGCTTCCGAGGTGGCGCGGCTCCTCCGGCCCTTCCTCCCGTGGATCGCACT
CTCCACCGTGTGCGGCCTGGCCGCCGGCATCGCCACCGTGCTGCTGCTGCGCACGGTCAACGAAGTGCTGCACAGCGACG
GCGGCATGTCCGGCGGCCTGCTGTGGACCTTCGTCGCCCTGTGCGCCGCCGCGCTCTTCGGGCGCCTGGCGGCCGACGTG
TCCACCAACTACGTCGGCCAGAAACTGGTGGCGCAGGTGCGCGTCGGCCTGGCCCGGAAAATCCTGTCGGCCCCCATCGA
CGCGCTGGAGCGCTACCGCACCCACCGGCTCATGCCCGTGCTGTCGCAGGACGTGGACATGATCAGCGACGCCGCCTTCG
TGCTGTCGTCCGCGCTCATCGCCTCGGCCGTGATGCTGGGCTGCCTCGTGTACATGGCCTGGCTGTCCCTGCCGCTCTTC
GGCCTCGTGGTGCTGGCCCTGGCCATCGGCGCCAGCCTGCAGGTCGTGGCGCAGACCCGGGCCGAAAAAGGCTTCTGGAA
GGCCCGCGAACACGAAGACAACCTGCACAAGGCCTACCGCGCCATCAGCGAAGGCGCGAAGGAACTGCGCATGCACCGCG
AGCGCCGCGCCCGCATGCTGGACGGGCAGGTGGAGCGCATCGTGGCCCAAATCCGCCAGGTCAACGGCCGCGCCATCAAC
ACCTACGTCACCGCCACCGCCTTCGGCTCCGCGCTGTTCTTCCTGCTCATCGCCATGATCCTCGGCTGGGCCGCCTTCCA
GCCCACCGAGCCGGCGGTGCTCAGCGGCTTCGCGCTGGTGCTGCTCTTCCTCAAGGGCCCCATCGACCAGATCGCCGCCA
CGCTGCCCCACATGGGCCGCGCCAAGGTGGCTTTCCTGCGCATCGCCGACCTGTCGGCACGCTTCGCCACGCCGGAGCCC
CACCTGCACCAGGACCGCCCCGCGCCCGCCCCCGTGCTGCACGAAGGCATCTCGCTGCAGGGCGTGCGCTACGCCTTCGA
GGCGCCCGCCGACGGCGGCGAGCCCTTCGCGCTCGGCCCCGTGGACCTGGAGCTGCGCCGCGGCGAAATGGTCTTCATCG
TGGGCGACAACGGCTCGGGCAAGACCACCCTCATCAAGCTGCTGCTGGGCCTGTATGCCCCGCAGGAGGGCGAAGTGCTG
ATCGACGGCGTGGCCGTCACCGCCGAGTCGCGCGACGACTACCGCCAGCTCTTCACCACCGTGCTCTCGGACTTCTACCT
CTTCGAGGACCTGGCCGGTGCCGGGGAGGGCGGGGCGGGCATGGCGGCCCTGCCCGAGGCAGCGCGCCCCTACCTGGAGC
GCCTGGAGATCGCCCACAAGGTGAGCATCCGGGACGGCGCCTTCAGCACCGTCGATCTGTCCACCGGCCAGCGCAAGCGC
CTCGCGCTGGTGCATGCCTACCTCGAGGGCCGCCCGGTCATGGTGTTCGACGAATGGGCCGCGGACCAGGACCCGGCCTT
CCGCCACCTCTTCTACACCGAACTGCTGCCCGAACTGCGCGCCAAAGGGCACCTGCTGGTCGTGATCTCGCACGACGACC
GCTACTTCCACCTGGCCGACCGCGTCGTCCACATGAGCGCGGGCCGCATCGCCGACAACCGCGTGCGCGCCGGCCGCGAA
ACCCTGGCCGCCTGA

Upstream 100 bases:

>100_bases
GGAACCCCCTGCGCATGAACATCCCCGCGCCCGCAGCGTCTTTGGAGCAGGCGTCCCGCCTTGCAACCCAGCCCCCGACG
GGCGGAAAGAGATCTTGCGC

Downstream 100 bases:

>100_bases
CCGTCCGAATCCCGGTGCGGCCGCGAGCCGGCCGGCCCGTCCCTTTTTCAAAGGAGTTGTCATCCCATGCAGCACATCCA
TGACCTGATCGGTATCGGCT

Product: cyclic peptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 564; Mature: 563

Protein sequence:

>564_residues
MTAAPAPRAPASEVARLLRPFLPWIALSTVCGLAAGIATVLLLRTVNEVLHSDGGMSGGLLWTFVALCAAALFGRLAADV
STNYVGQKLVAQVRVGLARKILSAPIDALERYRTHRLMPVLSQDVDMISDAAFVLSSALIASAVMLGCLVYMAWLSLPLF
GLVVLALAIGASLQVVAQTRAEKGFWKAREHEDNLHKAYRAISEGAKELRMHRERRARMLDGQVERIVAQIRQVNGRAIN
TYVTATAFGSALFFLLIAMILGWAAFQPTEPAVLSGFALVLLFLKGPIDQIAATLPHMGRAKVAFLRIADLSARFATPEP
HLHQDRPAPAPVLHEGISLQGVRYAFEAPADGGEPFALGPVDLELRRGEMVFIVGDNGSGKTTLIKLLLGLYAPQEGEVL
IDGVAVTAESRDDYRQLFTTVLSDFYLFEDLAGAGEGGAGMAALPEAARPYLERLEIAHKVSIRDGAFSTVDLSTGQRKR
LALVHAYLEGRPVMVFDEWAADQDPAFRHLFYTELLPELRAKGHLLVVISHDDRYFHLADRVVHMSAGRIADNRVRAGRE
TLAA

Sequences:

>Translated_564_residues
MTAAPAPRAPASEVARLLRPFLPWIALSTVCGLAAGIATVLLLRTVNEVLHSDGGMSGGLLWTFVALCAAALFGRLAADV
STNYVGQKLVAQVRVGLARKILSAPIDALERYRTHRLMPVLSQDVDMISDAAFVLSSALIASAVMLGCLVYMAWLSLPLF
GLVVLALAIGASLQVVAQTRAEKGFWKAREHEDNLHKAYRAISEGAKELRMHRERRARMLDGQVERIVAQIRQVNGRAIN
TYVTATAFGSALFFLLIAMILGWAAFQPTEPAVLSGFALVLLFLKGPIDQIAATLPHMGRAKVAFLRIADLSARFATPEP
HLHQDRPAPAPVLHEGISLQGVRYAFEAPADGGEPFALGPVDLELRRGEMVFIVGDNGSGKTTLIKLLLGLYAPQEGEVL
IDGVAVTAESRDDYRQLFTTVLSDFYLFEDLAGAGEGGAGMAALPEAARPYLERLEIAHKVSIRDGAFSTVDLSTGQRKR
LALVHAYLEGRPVMVFDEWAADQDPAFRHLFYTELLPELRAKGHLLVVISHDDRYFHLADRVVHMSAGRIADNRVRAGRE
TLAA
>Mature_563_residues
TAAPAPRAPASEVARLLRPFLPWIALSTVCGLAAGIATVLLLRTVNEVLHSDGGMSGGLLWTFVALCAAALFGRLAADVS
TNYVGQKLVAQVRVGLARKILSAPIDALERYRTHRLMPVLSQDVDMISDAAFVLSSALIASAVMLGCLVYMAWLSLPLFG
LVVLALAIGASLQVVAQTRAEKGFWKAREHEDNLHKAYRAISEGAKELRMHRERRARMLDGQVERIVAQIRQVNGRAINT
YVTATAFGSALFFLLIAMILGWAAFQPTEPAVLSGFALVLLFLKGPIDQIAATLPHMGRAKVAFLRIADLSARFATPEPH
LHQDRPAPAPVLHEGISLQGVRYAFEAPADGGEPFALGPVDLELRRGEMVFIVGDNGSGKTTLIKLLLGLYAPQEGEVLI
DGVAVTAESRDDYRQLFTTVLSDFYLFEDLAGAGEGGAGMAALPEAARPYLERLEIAHKVSIRDGAFSTVDLSTGQRKRL
ALVHAYLEGRPVMVFDEWAADQDPAFRHLFYTELLPELRAKGHLLVVISHDDRYFHLADRVVHMSAGRIADNRVRAGRET
LAA

Specific function: ATP-driven efflux pump necessary for the secretion of syringomycin. May specifically bind syringomycin and translocate it to the periplasmic space. SyrD is also required for full expression of the syrB gene [H]

COG id: COG4615

COG function: function code QP; ABC-type siderophore export system, fused ATPase and permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI9955966, Length=512, Percent_Identity=20.5078125, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI45243524, Length=512, Percent_Identity=20.5078125, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1788540, Length=541, Percent_Identity=32.1626617375231, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI1787029, Length=202, Percent_Identity=30.1980198019802, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1787143, Length=518, Percent_Identity=21.6216216216216, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1786253, Length=211, Percent_Identity=29.8578199052133, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1789032, Length=205, Percent_Identity=32.6829268292683, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787112, Length=513, Percent_Identity=23.7816764132554, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1786654, Length=427, Percent_Identity=22.7166276346604, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1787105, Length=224, Percent_Identity=27.6785714285714, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1789672, Length=212, Percent_Identity=25.9433962264151, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87081709, Length=211, Percent_Identity=27.9620853080569, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI48995001, Length=209, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI87082267, Length=216, Percent_Identity=26.3888888888889, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1787370, Length=223, Percent_Identity=27.3542600896861, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1786872, Length=186, Percent_Identity=29.5698924731183, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788225, Length=214, Percent_Identity=29.4392523364486, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI87081834, Length=206, Percent_Identity=29.6116504854369, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI48994943, Length=202, Percent_Identity=28.2178217821782, Blast_Score=63, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI193209708, Length=526, Percent_Identity=22.8136882129278, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI115534520, Length=321, Percent_Identity=23.6760124610592, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17565938, Length=479, Percent_Identity=20.8768267223382, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17533971, Length=531, Percent_Identity=22.0338983050847, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71984940, Length=581, Percent_Identity=20.9982788296041, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17543740, Length=245, Percent_Identity=24.4897959183673, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17567269, Length=259, Percent_Identity=26.6409266409266, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71996550, Length=157, Percent_Identity=30.5732484076433, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI193202349, Length=542, Percent_Identity=22.6937269372694, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17558664, Length=234, Percent_Identity=26.0683760683761, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17567265, Length=205, Percent_Identity=26.8292682926829, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17510237, Length=202, Percent_Identity=26.2376237623762, Blast_Score=66, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI193208177, Length=205, Percent_Identity=23.9024390243902, Blast_Score=65, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI115535101, Length=263, Percent_Identity=25.8555133079848, Blast_Score=65, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6323959, Length=186, Percent_Identity=25.8064516129032, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI28574259, Length=383, Percent_Identity=25.5874673629243, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24666092, Length=238, Percent_Identity=25.6302521008403, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24659289, Length=510, Percent_Identity=22.7450980392157, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24641565, Length=497, Percent_Identity=23.943661971831, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281363262, Length=289, Percent_Identity=24.5674740484429, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24653245, Length=289, Percent_Identity=24.5674740484429, Blast_Score=66, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017940
- InterPro:   IPR001140
- InterPro:   IPR011527
- InterPro:   IPR003593
- InterPro:   IPR005898 [H]

Pfam domain/function: PF00664 ABC_membrane; PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 61274; Mature: 61143

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: PS50893 ABC_TRANSPORTER_2 ; PS50929 ABC_TM1F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAAPAPRAPASEVARLLRPFLPWIALSTVCGLAAGIATVLLLRTVNEVLHSDGGMSGGL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
LWTFVALCAAALFGRLAADVSTNYVGQKLVAQVRVGLARKILSAPIDALERYRTHRLMPV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
LSQDVDMISDAAFVLSSALIASAVMLGCLVYMAWLSLPLFGLVVLALAIGASLQVVAQTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
AEKGFWKAREHEDNLHKAYRAISEGAKELRMHRERRARMLDGQVERIVAQIRQVNGRAIN
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCEEE
TYVTATAFGSALFFLLIAMILGWAAFQPTEPAVLSGFALVLLFLKGPIDQIAATLPHMGR
HEEHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCCC
AKVAFLRIADLSARFATPEPHLHQDRPAPAPVLHEGISLQGVRYAFEAPADGGEPFALGP
CCEEEEEEECCHHHCCCCCCCCCCCCCCCCHHHHCCCCCCCEEEEEECCCCCCCCEEECC
VDLELRRGEMVFIVGDNGSGKTTLIKLLLGLYAPQEGEVLIDGVAVTAESRDDYRQLFTT
CCEEEECCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEEEEEEECCHHHHHHHHHH
VLSDFYLFEDLAGAGEGGAGMAALPEAARPYLERLEIAHKVSIRDGAFSTVDLSTGQRKR
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEECCCCCEEEECCCCCHHH
LALVHAYLEGRPVMVFDEWAADQDPAFRHLFYTELLPELRAKGHLLVVISHDDRYFHLAD
HHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEHHHH
RVVHMSAGRIADNRVRAGRETLAA
HHHHHHCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TAAPAPRAPASEVARLLRPFLPWIALSTVCGLAAGIATVLLLRTVNEVLHSDGGMSGGL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
LWTFVALCAAALFGRLAADVSTNYVGQKLVAQVRVGLARKILSAPIDALERYRTHRLMPV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
LSQDVDMISDAAFVLSSALIASAVMLGCLVYMAWLSLPLFGLVVLALAIGASLQVVAQTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
AEKGFWKAREHEDNLHKAYRAISEGAKELRMHRERRARMLDGQVERIVAQIRQVNGRAIN
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCEEE
TYVTATAFGSALFFLLIAMILGWAAFQPTEPAVLSGFALVLLFLKGPIDQIAATLPHMGR
HEEHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCCC
AKVAFLRIADLSARFATPEPHLHQDRPAPAPVLHEGISLQGVRYAFEAPADGGEPFALGP
CCEEEEEEECCHHHCCCCCCCCCCCCCCCCHHHHCCCCCCCEEEEEECCCCCCCCEEECC
VDLELRRGEMVFIVGDNGSGKTTLIKLLLGLYAPQEGEVLIDGVAVTAESRDDYRQLFTT
CCEEEECCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEEEEEEECCHHHHHHHHHH
VLSDFYLFEDLAGAGEGGAGMAALPEAARPYLERLEIAHKVSIRDGAFSTVDLSTGQRKR
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEECCCCCEEEECCCCCHHH
LALVHAYLEGRPVMVFDEWAADQDPAFRHLFYTELLPELRAKGHLLVVISHDDRYFHLAD
HHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEHHHH
RVVHMSAGRIADNRVRAGRETLAA
HHHHHHCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8231810 [H]