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The map label for this gene is coaE [H]

Identifier: 120612327

GI number: 120612327

Start: 4061071

End: 4061697

Strand: Direct

Name: coaE [H]

Synonym: Aave_3683

Alternate gene names: 120612327

Gene position: 4061071-4061697 (Clockwise)

Preceding gene: 120612326

Following gene: 120612328

Centisome position: 75.87

GC content: 73.21

Gene sequence:

>627_bases
GTGACGGATGCGGCGCCCCGCCCTGCCCCGCTGCGGCTGGGCCTGACGGGCGGCATCGGCAGCGGCAAGACGACCGTCGG
CCAGTGGCTGCAGGAGTTCGGGGCCGCGCTGGTGGATGCGGACCGGATCGCCCGCTCGGCGACGGCGGCCGGCGGCCTCG
CCATTCCCGCGATCCGCAGTGCCTTCGGCGACGGCATGATCGATGCCGATGGCGCCATGGACCGGGCCCGCATGCGGGAG
CTGGCCTTCCGGGATGCCGGGGCGCGGCAGAGGCTGGAGGCGATCGTCCATCCGCTGGTGGCCCAGGCCATCCATGCGGA
GGCGGAGCGGGCCGCGGCCGATGGCGCCAGGGTGGTGGTGTTCGACATTCCCCTGCTGGCGGAGTCGGATAGATGGCCTC
CCCAGCTCGACCGCATCCTGGTGGTGGACTGCTCCGAGGCGACCCAGGTGGCGCGCGTGCAGGCCCGCAGCGGGCTGGCC
CCGGACACCGTGCAGGCCATCATCGCCTCGCAGGCGCCGCGGGCCGCACGCCGCGCCGTCGCGGACATGGTGCTCCACAA
CGACCGAATACCTTTGGATACCCTGCGGACGGAGGTCCGGCGAATCGCCGATGGCTTCGGGCTATGA

Upstream 100 bases:

>100_bases
ACTACATCCCCTTCGGCCCGTTCCTCGCCGGCGCCGGGCTCGCCGCCATGCTGTTCGGGCCCGACCGCATATTGAACGGC
ATCCTGGGAGCGCTGGGCCT

Downstream 100 bases:

>100_bases
TGCGGGCGATATGGGATGCGCGATGCTGGCGGCGCCAGCCGTGCGCCCCCAGGAACCCTGCAGCGTGATTCTTTACGAAT
ACCCCTTCAACGAACGCCTC

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MTDAAPRPAPLRLGLTGGIGSGKTTVGQWLQEFGAALVDADRIARSATAAGGLAIPAIRSAFGDGMIDADGAMDRARMRE
LAFRDAGARQRLEAIVHPLVAQAIHAEAERAAADGARVVVFDIPLLAESDRWPPQLDRILVVDCSEATQVARVQARSGLA
PDTVQAIIASQAPRAARRAVADMVLHNDRIPLDTLRTEVRRIADGFGL

Sequences:

>Translated_208_residues
MTDAAPRPAPLRLGLTGGIGSGKTTVGQWLQEFGAALVDADRIARSATAAGGLAIPAIRSAFGDGMIDADGAMDRARMRE
LAFRDAGARQRLEAIVHPLVAQAIHAEAERAAADGARVVVFDIPLLAESDRWPPQLDRILVVDCSEATQVARVQARSGLA
PDTVQAIIASQAPRAARRAVADMVLHNDRIPLDTLRTEVRRIADGFGL
>Mature_207_residues
TDAAPRPAPLRLGLTGGIGSGKTTVGQWLQEFGAALVDADRIARSATAAGGLAIPAIRSAFGDGMIDADGAMDRARMREL
AFRDAGARQRLEAIVHPLVAQAIHAEAERAAADGARVVVFDIPLLAESDRWPPQLDRILVVDCSEATQVARVQARSGLAP
DTVQAIIASQAPRAARRAVADMVLHNDRIPLDTLRTEVRRIADGFGL

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=175, Percent_Identity=34.8571428571429, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI191252795, Length=175, Percent_Identity=34.8571428571429, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI110227607, Length=159, Percent_Identity=32.0754716981132, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI205277394, Length=159, Percent_Identity=32.0754716981132, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI110227605, Length=159, Percent_Identity=32.0754716981132, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI110227603, Length=159, Percent_Identity=32.0754716981132, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI110227601, Length=159, Percent_Identity=32.0754716981132, Blast_Score=82, Evalue=5e-16,
Organism=Escherichia coli, GI1786292, Length=194, Percent_Identity=37.6288659793814, Blast_Score=114, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17554944, Length=196, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6320402, Length=192, Percent_Identity=31.25, Blast_Score=84, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24644728, Length=176, Percent_Identity=28.4090909090909, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24658602, Length=182, Percent_Identity=32.4175824175824, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22012; Mature: 21881

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDAAPRPAPLRLGLTGGIGSGKTTVGQWLQEFGAALVDADRIARSATAAGGLAIPAIRS
CCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AFGDGMIDADGAMDRARMRELAFRDAGARQRLEAIVHPLVAQAIHAEAERAAADGARVVV
HHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
FDIPLLAESDRWPPQLDRILVVDCSEATQVARVQARSGLAPDTVQAIIASQAPRAARRAV
EECCEECCCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHH
ADMVLHNDRIPLDTLRTEVRRIADGFGL
HHHHHCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TDAAPRPAPLRLGLTGGIGSGKTTVGQWLQEFGAALVDADRIARSATAAGGLAIPAIRS
CCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AFGDGMIDADGAMDRARMRELAFRDAGARQRLEAIVHPLVAQAIHAEAERAAADGARVVV
HHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
FDIPLLAESDRWPPQLDRILVVDCSEATQVARVQARSGLAPDTVQAIIASQAPRAARRAV
EECCEECCCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHH
ADMVLHNDRIPLDTLRTEVRRIADGFGL
HHHHHCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA