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The map label for this gene is qor [H]

Identifier: 120612121

GI number: 120612121

Start: 3832031

End: 3833017

Strand: Reverse

Name: qor [H]

Synonym: Aave_3468

Alternate gene names: 120612121

Gene position: 3833017-3832031 (Counterclockwise)

Preceding gene: 120612123

Following gene: 120612120

Centisome position: 71.61

GC content: 69.91

Gene sequence:

>987_bases
ATGAGCCTTGCCGTCCAGATCCGCCAGCACGGCGGTCCCGAAGAACTGCACCTGACCGACGTGACCGTGGGCGAGCCCGG
CCCCGGCGAGATCCGCATCCGCCACCATGCGGTGGGCCTGAATTTCATCGACGTGTACCACCGCACGGGGCTGTATCCGC
TGCCGATGCCGGCCACGATCGGCATGGAGGGCGCGGGCATCGTCGAGGCCGTGGGCGCGGGCGTGACGCACCTGGCCGTG
GGCGACCGCGCCGCGTATGCGAGCCAGCCGCCCGGCAGCTATGCCGAGGTGCGTGTGCTGCCCGCGAAGTGCGTGTGCCG
GCTGCCCGACGCGATAGATTTCGAGACCGGCGCGGCGATGATGCTCAAGGGCCTGACGGCGCAGTACCTGCTGAAGAAAA
CGCTGCCGGCCGAAGGCCTGCAGCCGGGCGACCACGTGCTGTTCCATGCGGCCGCGGGCGGCGTGGGGCTGATCGCCTGC
CAGTGGGCGAAGGCGCTGGGCCTGCAGCTCATCGGCACGGCGGGCAGCGACGAGAAGTGCCAGCTGGCGCTCGCCAACGG
CGCGGCGCATGCCATCAACTACCGCACCGAGGATTTCGCGGCGCGCGTGAAGGAGATCACGGGCGGCAAGGGCGTGAAGG
TGGTGTACGACTCGGTGGGCAAGGACACCTGGGAGAAGTCGCTGGAGTGCCTGCGGCCCTTCGGCCTGATGGCCACCTTC
GGCAATGCCTCGGGCCCGGCGCCGGCGTTCGCGCCCGGCATGCTGGGCGCCAAGGGATCGCTCTACGTCACGCGGCAGAC
GCTGTTCACGCACATCGCCACGCGCGAATCCACCCAGGCCATGGCGGACGACCTGTTCGCGGTGGTGCAGAGCGGCGACG
TGTCGATCCACATCGACCAGCGCTACCCGCTGCGCGACGTGCAGCAGGCGCACCGCGACCTGGAAGCGCGCAAGACCACG
GGCTCCACCATCCTGACGCTGGAATGA

Upstream 100 bases:

>100_bases
GGCCATTCCGCGGGCCGGATGCCCGTCCGCATTGCCCCGGTCCGCGTTCCCGATTTTTTCCTTTCTTTTTGATCGTGTCT
TCCATCGCAGGAGTCGCCGC

Downstream 100 bases:

>100_bases
GCGGGCATTGCGAGATGCCGGTGCCCGCGTGGGTGGCACCGGCCCGCGCGCTGGCGCACCGGCCGGCTATGGTGCCGCGT
GTGCTGTTCGCCGTGGCCGG

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MSLAVQIRQHGGPEELHLTDVTVGEPGPGEIRIRHHAVGLNFIDVYHRTGLYPLPMPATIGMEGAGIVEAVGAGVTHLAV
GDRAAYASQPPGSYAEVRVLPAKCVCRLPDAIDFETGAAMMLKGLTAQYLLKKTLPAEGLQPGDHVLFHAAAGGVGLIAC
QWAKALGLQLIGTAGSDEKCQLALANGAAHAINYRTEDFAARVKEITGGKGVKVVYDSVGKDTWEKSLECLRPFGLMATF
GNASGPAPAFAPGMLGAKGSLYVTRQTLFTHIATRESTQAMADDLFAVVQSGDVSIHIDQRYPLRDVQQAHRDLEARKTT
GSTILTLE

Sequences:

>Translated_328_residues
MSLAVQIRQHGGPEELHLTDVTVGEPGPGEIRIRHHAVGLNFIDVYHRTGLYPLPMPATIGMEGAGIVEAVGAGVTHLAV
GDRAAYASQPPGSYAEVRVLPAKCVCRLPDAIDFETGAAMMLKGLTAQYLLKKTLPAEGLQPGDHVLFHAAAGGVGLIAC
QWAKALGLQLIGTAGSDEKCQLALANGAAHAINYRTEDFAARVKEITGGKGVKVVYDSVGKDTWEKSLECLRPFGLMATF
GNASGPAPAFAPGMLGAKGSLYVTRQTLFTHIATRESTQAMADDLFAVVQSGDVSIHIDQRYPLRDVQQAHRDLEARKTT
GSTILTLE
>Mature_327_residues
SLAVQIRQHGGPEELHLTDVTVGEPGPGEIRIRHHAVGLNFIDVYHRTGLYPLPMPATIGMEGAGIVEAVGAGVTHLAVG
DRAAYASQPPGSYAEVRVLPAKCVCRLPDAIDFETGAAMMLKGLTAQYLLKKTLPAEGLQPGDHVLFHAAAGGVGLIACQ
WAKALGLQLIGTAGSDEKCQLALANGAAHAINYRTEDFAARVKEITGGKGVKVVYDSVGKDTWEKSLECLRPFGLMATFG
NASGPAPAFAPGMLGAKGSLYVTRQTLFTHIATRESTQAMADDLFAVVQSGDVSIHIDQRYPLRDVQQAHRDLEARKTTG
STILTLE

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=329, Percent_Identity=34.6504559270517, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI13236495, Length=329, Percent_Identity=34.6504559270517, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI22538446, Length=335, Percent_Identity=32.2388059701493, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI22538444, Length=335, Percent_Identity=32.2388059701493, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI194239676, Length=329, Percent_Identity=33.1306990881459, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI18379349, Length=323, Percent_Identity=30.9597523219814, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI24308257, Length=350, Percent_Identity=27.7142857142857, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI28557745, Length=230, Percent_Identity=35.2173913043478, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI197927207, Length=194, Percent_Identity=33.5051546391753, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI156627571, Length=236, Percent_Identity=27.9661016949153, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1790485, Length=328, Percent_Identity=51.219512195122, Blast_Score=338, Evalue=3e-94,
Organism=Caenorhabditis elegans, GI17507255, Length=331, Percent_Identity=26.5861027190332, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17556000, Length=264, Percent_Identity=26.8939393939394, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562876, Length=232, Percent_Identity=28.0172413793103, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=327, Percent_Identity=37.9204892966361, Blast_Score=202, Evalue=8e-53,
Organism=Saccharomyces cerevisiae, GI6319621, Length=257, Percent_Identity=28.0155642023346, Blast_Score=73, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34745; Mature: 34614

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLAVQIRQHGGPEELHLTDVTVGEPGPGEIRIRHHAVGLNFIDVYHRTGLYPLPMPATI
CCEEEEEECCCCCCEEEEEEEECCCCCCCCEEEEEEEECCHHEEHHHHCCCCCCCCCCCC
GMEGAGIVEAVGAGVTHLAVGDRAAYASQPPGSYAEVRVLPAKCVCRLPDAIDFETGAAM
CCCCCCHHHHHCCCEEEEEECCCCCCCCCCCCCCEEEEEECHHHHCCCCCCCCCCCCHHH
MLKGLTAQYLLKKTLPAEGLQPGDHVLFHAAAGGVGLIACQWAKALGLQLIGTAGSDEKC
HHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEEEEHHHHHCCEEEEECCCCCCCE
QLALANGAAHAINYRTEDFAARVKEITGGKGVKVVYDSVGKDTWEKSLECLRPFGLMATF
EEEEECCCEEEEECCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEC
GNASGPAPAFAPGMLGAKGSLYVTRQTLFTHIATRESTQAMADDLFAVVQSGDVSIHIDQ
CCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHCHHHHHHHHHHHHHHCCCCEEEEECC
RYPLRDVQQAHRDLEARKTTGSTILTLE
CCCHHHHHHHHHHHHHHCCCCCEEEEEC
>Mature Secondary Structure 
SLAVQIRQHGGPEELHLTDVTVGEPGPGEIRIRHHAVGLNFIDVYHRTGLYPLPMPATI
CEEEEEECCCCCCEEEEEEEECCCCCCCCEEEEEEEECCHHEEHHHHCCCCCCCCCCCC
GMEGAGIVEAVGAGVTHLAVGDRAAYASQPPGSYAEVRVLPAKCVCRLPDAIDFETGAAM
CCCCCCHHHHHCCCEEEEEECCCCCCCCCCCCCCEEEEEECHHHHCCCCCCCCCCCCHHH
MLKGLTAQYLLKKTLPAEGLQPGDHVLFHAAAGGVGLIACQWAKALGLQLIGTAGSDEKC
HHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEEEEHHHHHCCEEEEECCCCCCCE
QLALANGAAHAINYRTEDFAARVKEITGGKGVKVVYDSVGKDTWEKSLECLRPFGLMATF
EEEEECCCEEEEECCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEC
GNASGPAPAFAPGMLGAKGSLYVTRQTLFTHIATRESTQAMADDLFAVVQSGDVSIHIDQ
CCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHCHHHHHHHHHHHHHHCCCCEEEEECC
RYPLRDVQQAHRDLEARKTTGSTILTLE
CCCHHHHHHHHHHHHHHCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]