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The map label for this gene is lspA [H]

Identifier: 120612104

GI number: 120612104

Start: 3814104

End: 3814613

Strand: Direct

Name: lspA [H]

Synonym: Aave_3451

Alternate gene names: 120612104

Gene position: 3814104-3814613 (Clockwise)

Preceding gene: 120612103

Following gene: 120612106

Centisome position: 71.25

GC content: 68.43

Gene sequence:

>510_bases
ATGGCCCGCGGCAACGCTTCTTCCTCCGCATCCGGCAAGGGCTCGCTGTGGCCCTGGCTGGCCTGGGCCGTGCTGCTGCT
GGTGGCCGACCAGTTCACCAAGACGCTGATCCTGGGCTACTACCGCCTGGGCGACGCCACCTACGTCACCAGCTTCTTCA
ACATCGTGCGGGCGCACAACACCGGCGCGGCGTTCTCGTTCCTGGCCAACGCGGGCGGCTGGCAGCGCTGGGTGTTCACC
GGCATCGGCGTGGCGGCGGCGTTCTTCATCGTCTGGCAGCTGCGCGCCCACCCCGGGCAGAAGCTGTTCTGCTTCGCGCT
CTCCAGCATCCTGGGCGGCGCCATCGGCAACGTGGTGGACCGCATGATGCACGGCTACGTGGTGGACTTCCTGGACTTCC
ACGCACGCGGCTGGCACTTCCCGGCCTTCAACCTGGCCGACTCCGCGATCACGATCGGCGCGGCCTGCCTGATCATCGAC
GAGCTGATGCGGGTGCGGCGGGGCAGCTGA

Upstream 100 bases:

>100_bases
CTACCGCGCCGACGTGGGCCGGGACGCTGCCCACCCGACCATCTGCGGCCGGTGCGTGAGCAACCTGTACGGCAGCGGCG
AGACACGGGAGCACGCATAA

Downstream 100 bases:

>100_bases
ACGCACGCCGGATGCCACCGGCCCGGGGCGCGTCGGGCCGTCAGGACGTTCTCCGGCGGAGCCGGCAGGCGGCGCCGTAC
AGCAAGGCGGGCACTTCTGC

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 169; Mature: 168

Protein sequence:

>169_residues
MARGNASSSASGKGSLWPWLAWAVLLLVADQFTKTLILGYYRLGDATYVTSFFNIVRAHNTGAAFSFLANAGGWQRWVFT
GIGVAAAFFIVWQLRAHPGQKLFCFALSSILGGAIGNVVDRMMHGYVVDFLDFHARGWHFPAFNLADSAITIGAACLIID
ELMRVRRGS

Sequences:

>Translated_169_residues
MARGNASSSASGKGSLWPWLAWAVLLLVADQFTKTLILGYYRLGDATYVTSFFNIVRAHNTGAAFSFLANAGGWQRWVFT
GIGVAAAFFIVWQLRAHPGQKLFCFALSSILGGAIGNVVDRMMHGYVVDFLDFHARGWHFPAFNLADSAITIGAACLIID
ELMRVRRGS
>Mature_168_residues
ARGNASSSASGKGSLWPWLAWAVLLLVADQFTKTLILGYYRLGDATYVTSFFNIVRAHNTGAAFSFLANAGGWQRWVFTG
IGVAAAFFIVWQLRAHPGQKLFCFALSSILGGAIGNVVDRMMHGYVVDFLDFHARGWHFPAFNLADSAITIGAACLIIDE
LMRVRRGS

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=161, Percent_Identity=44.0993788819876, Blast_Score=130, Evalue=5e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 18465; Mature: 18333

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARGNASSSASGKGSLWPWLAWAVLLLVADQFTKTLILGYYRLGDATYVTSFFNIVRAHN
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
TGAAFSFLANAGGWQRWVFTGIGVAAAFFIVWQLRAHPGQKLFCFALSSILGGAIGNVVD
CCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
RMMHGYVVDFLDFHARGWHFPAFNLADSAITIGAACLIIDELMRVRRGS
HHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ARGNASSSASGKGSLWPWLAWAVLLLVADQFTKTLILGYYRLGDATYVTSFFNIVRAHN
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
TGAAFSFLANAGGWQRWVFTGIGVAAAFFIVWQLRAHPGQKLFCFALSSILGGAIGNVVD
CCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
RMMHGYVVDFLDFHARGWHFPAFNLADSAITIGAACLIIDELMRVRRGS
HHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA