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The map label for this gene is ccpA [H]

Identifier: 120612106

GI number: 120612106

Start: 3815934

End: 3816926

Strand: Direct

Name: ccpA [H]

Synonym: Aave_3453

Alternate gene names: 120612106

Gene position: 3815934-3816926 (Clockwise)

Preceding gene: 120612104

Following gene: 120612107

Centisome position: 71.29

GC content: 73.21

Gene sequence:

>993_bases
ATGACCATCCAGCACGTCGCCCGCGAAGCCGGGGTTTCGGCCGCCACCGTTTCCCGGGTGTTCAATACGCCCGACAAGGT
GGTGCCCGCCACGCGCGCCGCGGTGCTCGGCGCCGCCGAGCGGCTGGGCTACGTGCCCAACGCCACGGCGCGCACGCTGC
GCACCCAGCGCAGCCACGTCATCGGCGTGGTGCTGCCCACGCTGCTGAACCCGGTGTTCGCGGAATGCCTGGACGGCATC
GCGCAGGCCGCGGCGCGGGGGGGCTACGCCATCCTGCCGTACACCACCGACTATGCGGTGGCGCAGGAAGAGCGCGCGGT
GCACCTGCTGCTGGCGGGCAATGTGGACGGCATGGTCCTCGTGGTGTCCCAGCCCCGGACCTCGGTGGCGCTGGAGCGGC
TGGCCGCGGCGCGACTGCCGTATGCGCTGGCCTACAACCGGCATCCGGACCATCCCTGTGTTTCCGTGGACGGCGAAGGC
GCCGTGGCGGAACTGGTCGCGCAACTGGCCGCGCTGGGGCACCGCCGCATCGCCATGGTGAGCGGGCAGCTCGCGGCGTC
CGACCGCGCGCAGCAGCGCTGCCGCGGCTTCATGCGCGGCATGGCGCAGGCGGGGCTGGCCCCGGCGCGGGTCGTGGAAG
TGCCCTTCGTCGAGACCGCCGTGCAGGAGGTGGCCGAGCTGCTGCGCGGCCCGCGGCCCCCCACCGCCCTGGTCTGCTCC
AACGACCTGATCGCGATCCGCTGCCTGCGCGCGGCGCACATGGCGGGCCTGGAGGTGCCGCGCGACCTCAGCGTGGTGGG
CTTCGACGGCATCGCGCTGGGCAGGGACCTGACGCCCGTGCTCGGCACGGTGGCGCAGCCCAATGTCGATATCGGCCGCT
GCAGCGTGGAACTGCTGATCGAGGCCATGGCGTCGCACCGGCTGCCCACCCGGGAAGACAGCCTGACGCTGCCCCATCAC
TTCCGCGCGGGAGGGTCGTGCGCGGCCATCTGA

Upstream 100 bases:

>100_bases
CCCGGGGCACTGCCCTGCTGTCATCGCCCCGTCACGCGGCCGGGCTCCAATGCCATGAAATCGATTACATGACCTGTTTC
CCGCCCTGTTCCGTCCTCCC

Downstream 100 bases:

>100_bases
CACCGACACTCGCGCCCCCTGCCCCGCCCAGATCGGTCCGTTCCGCCCGCTTTCTGCTTTTTCTCCGCCACGTTCCATCC
ACCCCCTTTTTCTTTCTTCG

Product: LacI family transcription regulator

Products: NA

Alternate protein names: Catabolite control protein [H]

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MTIQHVAREAGVSAATVSRVFNTPDKVVPATRAAVLGAAERLGYVPNATARTLRTQRSHVIGVVLPTLLNPVFAECLDGI
AQAAARGGYAILPYTTDYAVAQEERAVHLLLAGNVDGMVLVVSQPRTSVALERLAAARLPYALAYNRHPDHPCVSVDGEG
AVAELVAQLAALGHRRIAMVSGQLAASDRAQQRCRGFMRGMAQAGLAPARVVEVPFVETAVQEVAELLRGPRPPTALVCS
NDLIAIRCLRAAHMAGLEVPRDLSVVGFDGIALGRDLTPVLGTVAQPNVDIGRCSVELLIEAMASHRLPTREDSLTLPHH
FRAGGSCAAI

Sequences:

>Translated_330_residues
MTIQHVAREAGVSAATVSRVFNTPDKVVPATRAAVLGAAERLGYVPNATARTLRTQRSHVIGVVLPTLLNPVFAECLDGI
AQAAARGGYAILPYTTDYAVAQEERAVHLLLAGNVDGMVLVVSQPRTSVALERLAAARLPYALAYNRHPDHPCVSVDGEG
AVAELVAQLAALGHRRIAMVSGQLAASDRAQQRCRGFMRGMAQAGLAPARVVEVPFVETAVQEVAELLRGPRPPTALVCS
NDLIAIRCLRAAHMAGLEVPRDLSVVGFDGIALGRDLTPVLGTVAQPNVDIGRCSVELLIEAMASHRLPTREDSLTLPHH
FRAGGSCAAI
>Mature_329_residues
TIQHVAREAGVSAATVSRVFNTPDKVVPATRAAVLGAAERLGYVPNATARTLRTQRSHVIGVVLPTLLNPVFAECLDGIA
QAAARGGYAILPYTTDYAVAQEERAVHLLLAGNVDGMVLVVSQPRTSVALERLAAARLPYALAYNRHPDHPCVSVDGEGA
VAELVAQLAALGHRRIAMVSGQLAASDRAQQRCRGFMRGMAQAGLAPARVVEVPFVETAVQEVAELLRGPRPPTALVCSN
DLIAIRCLRAAHMAGLEVPRDLSVVGFDGIALGRDLTPVLGTVAQPNVDIGRCSVELLIEAMASHRLPTREDSLTLPHHF
RAGGSCAAI

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes such as the alpha- amylase (amyE) and the acetyl-coenzyme A synthetase (acsA); and in the positive regulation of genes involved in excretion of excess carbon such

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=308, Percent_Identity=33.7662337662338, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1790194, Length=332, Percent_Identity=29.5180722891566, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI48994940, Length=310, Percent_Identity=30.6451612903226, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1787948, Length=325, Percent_Identity=28.3076923076923, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1790715, Length=312, Percent_Identity=26.9230769230769, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1789202, Length=293, Percent_Identity=31.0580204778157, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1788474, Length=318, Percent_Identity=29.874213836478, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1789068, Length=307, Percent_Identity=31.9218241042345, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1787580, Length=317, Percent_Identity=28.0757097791798, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1786540, Length=308, Percent_Identity=30.8441558441558, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI1787906, Length=253, Percent_Identity=32.0158102766798, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790689, Length=248, Percent_Identity=26.2096774193548, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786268, Length=322, Percent_Identity=25.776397515528, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 34835; Mature: 34704

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIQHVAREAGVSAATVSRVFNTPDKVVPATRAAVLGAAERLGYVPNATARTLRTQRSHV
CCHHHHHHHHCCHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
IGVVLPTLLNPVFAECLDGIAQAAARGGYAILPYTTDYAVAQEERAVHLLLAGNVDGMVL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHCCCEEEEEEECCCCCEEE
VVSQPRTSVALERLAAARLPYALAYNRHPDHPCVSVDGEGAVAELVAQLAALGHRRIAMV
EEECCCHHHHHHHHHHHHCCCCEECCCCCCCCEEEECCCCHHHHHHHHHHHHCCCEEEEE
SGQLAASDRAQQRCRGFMRGMAQAGLAPARVVEVPFVETAVQEVAELLRGPRPPTALVCS
CCCHHHHHHHHHHHHHHHHHHHHCCCCCHHEEECCHHHHHHHHHHHHHCCCCCCEEEEEC
NDLIAIRCLRAAHMAGLEVPRDLSVVGFDGIALGRDLTPVLGTVAQPNVDIGRCSVELLI
CCHHHHHHHHHHHHHCCCCCCCCEEEECCCEECCCCCHHHHHHCCCCCCCHHHHHHHHHH
EAMASHRLPTREDSLTLPHHFRAGGSCAAI
HHHHHCCCCCCCCCCCCCHHHCCCCCCCCC
>Mature Secondary Structure 
TIQHVAREAGVSAATVSRVFNTPDKVVPATRAAVLGAAERLGYVPNATARTLRTQRSHV
CHHHHHHHHCCHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
IGVVLPTLLNPVFAECLDGIAQAAARGGYAILPYTTDYAVAQEERAVHLLLAGNVDGMVL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHCCCEEEEEEECCCCCEEE
VVSQPRTSVALERLAAARLPYALAYNRHPDHPCVSVDGEGAVAELVAQLAALGHRRIAMV
EEECCCHHHHHHHHHHHHCCCCEECCCCCCCCEEEECCCCHHHHHHHHHHHHCCCEEEEE
SGQLAASDRAQQRCRGFMRGMAQAGLAPARVVEVPFVETAVQEVAELLRGPRPPTALVCS
CCCHHHHHHHHHHHHHHHHHHHHCCCCCHHEEECCHHHHHHHHHHHHHCCCCCCEEEEEC
NDLIAIRCLRAAHMAGLEVPRDLSVVGFDGIALGRDLTPVLGTVAQPNVDIGRCSVELLI
CCHHHHHHHHHHHHHCCCCCCCCEEEECCCEECCCCCHHHHHHCCCCCCCHHHHHHHHHH
EAMASHRLPTREDSLTLPHHFRAGGSCAAI
HHHHHCCCCCCCCCCCCCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8200532 [H]