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The map label for this gene is lolA [H]

Identifier: 120612078

GI number: 120612078

Start: 3783027

End: 3783662

Strand: Reverse

Name: lolA [H]

Synonym: Aave_3425

Alternate gene names: 120612078

Gene position: 3783662-3783027 (Counterclockwise)

Preceding gene: 120612079

Following gene: 120612074

Centisome position: 70.69

GC content: 69.65

Gene sequence:

>636_bases
ATGATGAAACAGTGGATGGCGATCGCCGCGATCGCGGTCGGTGCGCAGAGCGCCTGGGCCGATGGCCTGGCGAGCCTGGA
GTCGTTCATGAAGGGCGCCCAGGCCGGGCGCGCGGATTTCACGCAGACCGTGACATCGCCCCCGAAGGACGGCCAGGCCT
CGCGCACCCGGACCTCCTCCGGCACCTTCGAGTTCCAGCGGCCGGGCCGCTTCAAGTTCACCTATACCAAGCCCTTCGCC
CAGACCATCGTGGCCGACGGCAAGTCGCTCTGGCTCTACGACGCCGACCTGAACCAGGTCACCCAGCGGGCGCAGGCGCA
GGCGCTGGGCACCACGCCCGCCGCGCTGCTGGCCTCCGCGCCGGACCTGCAGGCATTGCGCAAGGATTTCACCCTCGAAT
CCGCGCCGGACCAGGATGGCCTGCAGTGGGTGCTGGCCACCCCCAGGACCAGGGACGGCCAGCTCAAGAGCGTGCGCGTG
GGCTTCCAGGGCGAGCAGCTCGCGGCCCTGGACATCCTGGACAGCTTCGGCCAGCGCTCGGTGATCCGCTTCGCGAACGT
CCAGTCCAGCGCTTCCCTGCCGGCCTCCACTTTCGAGTTCAAGCCCCCGCAGGGCGCCGACGTGGTGCGCCAGTGA

Upstream 100 bases:

>100_bases
TGAGCGCGCTCACCGCGAGCGGGCAGCGCGAGGTGCTGGTGCCCCACCGCGAGTGACCGCCGGCATGCCGGAGCCTGGAC
GACAAGGATTGGATCGAAGC

Downstream 100 bases:

>100_bases
TGCCCTGCAAGGCCCGGCGCCGCCGGCCTGCCGCTAGATGTTGAGTCTCACGAGGTTGTTCACACCCGGAATGCGTGTGA
TGGGAGGCTGATGGCCGAGC

Product: outer membrane lipoprotein carrier protein LolA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MMKQWMAIAAIAVGAQSAWADGLASLESFMKGAQAGRADFTQTVTSPPKDGQASRTRTSSGTFEFQRPGRFKFTYTKPFA
QTIVADGKSLWLYDADLNQVTQRAQAQALGTTPAALLASAPDLQALRKDFTLESAPDQDGLQWVLATPRTRDGQLKSVRV
GFQGEQLAALDILDSFGQRSVIRFANVQSSASLPASTFEFKPPQGADVVRQ

Sequences:

>Translated_211_residues
MMKQWMAIAAIAVGAQSAWADGLASLESFMKGAQAGRADFTQTVTSPPKDGQASRTRTSSGTFEFQRPGRFKFTYTKPFA
QTIVADGKSLWLYDADLNQVTQRAQAQALGTTPAALLASAPDLQALRKDFTLESAPDQDGLQWVLATPRTRDGQLKSVRV
GFQGEQLAALDILDSFGQRSVIRFANVQSSASLPASTFEFKPPQGADVVRQ
>Mature_211_residues
MMKQWMAIAAIAVGAQSAWADGLASLESFMKGAQAGRADFTQTVTSPPKDGQASRTRTSSGTFEFQRPGRFKFTYTKPFA
QTIVADGKSLWLYDADLNQVTQRAQAQALGTTPAALLASAPDLQALRKDFTLESAPDQDGLQWVLATPRTRDGQLKSVRV
GFQGEQLAALDILDSFGQRSVIRFANVQSSASLPASTFEFKPPQGADVVRQ

Specific function: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the l

COG id: COG2834

COG function: function code M; Outer membrane lipoprotein-sorting protein

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolA family [H]

Homologues:

Organism=Escherichia coli, GI145693108, Length=203, Percent_Identity=33.0049261083744, Blast_Score=80, Evalue=9e-17,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004564
- InterPro:   IPR018323 [H]

Pfam domain/function: PF03548 LolA [H]

EC number: NA

Molecular weight: Translated: 22806; Mature: 22806

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKQWMAIAAIAVGAQSAWADGLASLESFMKGAQAGRADFTQTVTSPPKDGQASRTRTSS
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCC
GTFEFQRPGRFKFTYTKPFAQTIVADGKSLWLYDADLNQVTQRAQAQALGTTPAALLASA
CCEEECCCCCEEEEECCHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHCCCCHHHHHHCC
PDLQALRKDFTLESAPDQDGLQWVLATPRTRDGQLKSVRVGFQGEQLAALDILDSFGQRS
CCHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCC
VIRFANVQSSASLPASTFEFKPPQGADVVRQ
EEHHHCCCCCCCCCCCCCCCCCCCCCHHHCC
>Mature Secondary Structure
MMKQWMAIAAIAVGAQSAWADGLASLESFMKGAQAGRADFTQTVTSPPKDGQASRTRTSS
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCC
GTFEFQRPGRFKFTYTKPFAQTIVADGKSLWLYDADLNQVTQRAQAQALGTTPAALLASA
CCEEECCCCCEEEEECCHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHCCCCHHHHHHCC
PDLQALRKDFTLESAPDQDGLQWVLATPRTRDGQLKSVRVGFQGEQLAALDILDSFGQRS
CCHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCC
VIRFANVQSSASLPASTFEFKPPQGADVVRQ
EEHHHCCCCCCCCCCCCCCCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA