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The map label for this gene is ftsK2 [H]

Identifier: 120612079

GI number: 120612079

Start: 3783707

End: 3786046

Strand: Reverse

Name: ftsK2 [H]

Synonym: Aave_3426

Alternate gene names: 120612079

Gene position: 3786046-3783707 (Counterclockwise)

Preceding gene: 120612083

Following gene: 120612078

Centisome position: 70.73

GC content: 68.55

Gene sequence:

>2340_bases
ATGACGTACTCCCTCAACACCCTCAATGCTTCTGCCGGGGGCAGATCGGCGCCGCGCAGCATGGCCGCACGCTTCGGGCA
CGAGATCGGCCTGGTGGCCGGGCTGCTGGCCCTGGTTTTCTGGCTGCTGGCCCTGGCCAGCTATTCCGCGCAGGATGCGG
CCTGGTCCACGTCCGGTGCGCACGACAGCCGGCTGATGGCGAACTGGGCCGGACGCCTGGGCGCCTGGCTTGCCGATGGC
AGCTATTTCGCGCTCGGCTTTTCCGTATGGTGGTGCGTGGCCGCGGGCGTGCGCGCCTGGATCGCCTCGCTCGCGCGCTG
GATGCGCGGAGGGGAGTCCGCGACACCCGGCCAGAGCCCGCTGGCACGGCGGCTGATGTTCTGGATCGGCCTCGCCCTGC
TGCTGTGCGCGAGCACGGCCCTGGAGTGGTCGCGGCTGTACCGCCTGGAGCCGCTGCTGCCCGGGCACGCCGGCGGCGTG
CTCGGCTACATCACCGGCCCCGCCGGCGTGAAGTGGCTGGGTTTCACCGGCTCGGGCCTGGTGGCCGTGATAGCGGTCGT
GGCGGGCGCCGCGCTGGTGTTCCGCTTCTCCTGGGGCCAGCTGGCCGAACGGCTGGGCGGCCGCATCGACGGGCTGGTGC
AGTTCGGCCGGGCGCGCCGCGAGAAGGCCCGTGACGTCGCGGCCGGCAAGCGGGCCGCCCGCGAGCGCGAGGAGGTGGTG
CAGGAGGAGCGCCATGAAATCCAGGAGCACCATCCGCAGCCCGTGCAGATCATCGAGCCCGTGCTCATGGCCGACGCCCC
CCCGAGCGCGCGCGTGGTGAAGGAGCGGCAGAAGCCCCTCTTCACCGAAATGCCCGACAGCCGCCTGCCGCAGGTGGACC
TGCTCGATGGCGCGCAGGCGCGGCAGGAAACCGTGGCGCCGGAGACGCTGGAGATGACCAGCCGCCTCATCGAGAAGAAA
CTCAAGGACTTCGGCGTCGAGGTGCGCGTCGTGGCGGCCATGCCCGGGCCGGTGATCACCCGCTACGAAATCGAGCCCGC
CACCGGCGTGAAGGGTTCGCAGATCGTGAACCTCGCCAAGGACCTGGCCCGCTCGCTGTCGCTGGTCTCCATCCGCGTGA
TCGAGACCATCCCCGGCAAGAACTACATGGCACTGGAGCTGCCCAACGCCAAGCGCCAGTCGATCCGCCTCTCGGAGATC
CTGGGCTCGCAGATCTACCACGACGCCAAGAGCCTGCTCACCATGGGCCTGGGCAAGGACATCGTGGGCAATCCGGTGGT
GGCCGACCTCGCCAAGATGCCGCACGTGCTGGTGGCCGGTACCACGGGTTCTGGCAAGTCGGTGGGGATCAACGCCATGA
TCCTCTCGCTGCTCTACAAGGCAGAAGCGCGCGACGTGCGCCTGCTGATGATCGACCCCAAGATGCTGGAAATGTCGGTC
TACGAAGGCATTCCGCACCTGCTGGCGCCCGTGGTCACCGACATGAAGCAGGCCGCGCACGGCCTGAACTGGTGCGTGGC
CGAGATGGAGCGCCGCTACAAGCTCATGTCCAAGCTGGGCGTGCGCAACCTGGCGGGCTACAACACCAAGATCGACGAGG
CTAAGGCGCGCGAGGAATTCATCTACAACCCCTTCAGCCTCACCCCCGAGGAGCCCGAGCCGCTGGAGCGGCTGCCGCAC
ATCGTCGTCATCATCGACGAGCTGGCCGACCTCATGATGGTGGTGGGCAAGAAGATCGAGGAACTGATCGCACGGCTGGC
GCAGAAGGCGCGGGCGGCCGGCATCCACCTCATCCTGGCCACCCAGCGGCCCAGCGTCGACGTGATCACCGGCCTCATCA
AGGCCAACATCCCGACCCGGATCGCCTTCTCGGTGGGCTCGAAGATCGACAGCCGCACCATCCTGGACCAGATGGGCGCC
GAGGCGCTGCTGGGCATGGGCGACATGCTCTACATGGCCAGCGGCACCGGGCTGCCCATCCGCGTGCACGGCGCCTTCGT
CTCCGACGACGAAGTCCACCGCGTCGTCAGCTACCTCAAGAGCCAGGGCGAGCCCGACTATATCGAGGGCGTGCTCGAGG
GGGGCACCGTGGATGGCGACGATGGCGCCTTCGGCGAAGGCGGCGGGGGGGGTGAAGGCGGAGAAAAAGACCCCATGTAC
GACCAGGCGGTGGAAGTGGTCCTCAAGGACCGCAAGGCCAGCATCTCGTACGTGCAGCGCAAGCTGCGCATCGGCTACAA
CCGCTCCGCGCGCCTGCTGGAAGACATGGAGAAGGCCGGCCTCGTGAGCGCGCTCACCGCGAGCGGGCAGCGCGAGGTGC
TGGTGCCCCACCGCGAGTGA

Upstream 100 bases:

>100_bases
TAAGAAGCCGGCGAAGACCGGGCTGCCGCAGGGTCTGCATCCAGGACGCCGCGCCGACACGGCCGGGCAGGGCATCGGGT
AAGCTTGCCGCGCTTCGACT

Downstream 100 bases:

>100_bases
CCGCCGGCATGCCGGAGCCTGGACGACAAGGATTGGATCGAAGCATGATGAAACAGTGGATGGCGATCGCCGCGATCGCG
GTCGGTGCGCAGAGCGCCTG

Product: DNA translocase FtsK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 779; Mature: 778

Protein sequence:

>779_residues
MTYSLNTLNASAGGRSAPRSMAARFGHEIGLVAGLLALVFWLLALASYSAQDAAWSTSGAHDSRLMANWAGRLGAWLADG
SYFALGFSVWWCVAAGVRAWIASLARWMRGGESATPGQSPLARRLMFWIGLALLLCASTALEWSRLYRLEPLLPGHAGGV
LGYITGPAGVKWLGFTGSGLVAVIAVVAGAALVFRFSWGQLAERLGGRIDGLVQFGRARREKARDVAAGKRAAREREEVV
QEERHEIQEHHPQPVQIIEPVLMADAPPSARVVKERQKPLFTEMPDSRLPQVDLLDGAQARQETVAPETLEMTSRLIEKK
LKDFGVEVRVVAAMPGPVITRYEIEPATGVKGSQIVNLAKDLARSLSLVSIRVIETIPGKNYMALELPNAKRQSIRLSEI
LGSQIYHDAKSLLTMGLGKDIVGNPVVADLAKMPHVLVAGTTGSGKSVGINAMILSLLYKAEARDVRLLMIDPKMLEMSV
YEGIPHLLAPVVTDMKQAAHGLNWCVAEMERRYKLMSKLGVRNLAGYNTKIDEAKAREEFIYNPFSLTPEEPEPLERLPH
IVVIIDELADLMMVVGKKIEELIARLAQKARAAGIHLILATQRPSVDVITGLIKANIPTRIAFSVGSKIDSRTILDQMGA
EALLGMGDMLYMASGTGLPIRVHGAFVSDDEVHRVVSYLKSQGEPDYIEGVLEGGTVDGDDGAFGEGGGGGEGGEKDPMY
DQAVEVVLKDRKASISYVQRKLRIGYNRSARLLEDMEKAGLVSALTASGQREVLVPHRE

Sequences:

>Translated_779_residues
MTYSLNTLNASAGGRSAPRSMAARFGHEIGLVAGLLALVFWLLALASYSAQDAAWSTSGAHDSRLMANWAGRLGAWLADG
SYFALGFSVWWCVAAGVRAWIASLARWMRGGESATPGQSPLARRLMFWIGLALLLCASTALEWSRLYRLEPLLPGHAGGV
LGYITGPAGVKWLGFTGSGLVAVIAVVAGAALVFRFSWGQLAERLGGRIDGLVQFGRARREKARDVAAGKRAAREREEVV
QEERHEIQEHHPQPVQIIEPVLMADAPPSARVVKERQKPLFTEMPDSRLPQVDLLDGAQARQETVAPETLEMTSRLIEKK
LKDFGVEVRVVAAMPGPVITRYEIEPATGVKGSQIVNLAKDLARSLSLVSIRVIETIPGKNYMALELPNAKRQSIRLSEI
LGSQIYHDAKSLLTMGLGKDIVGNPVVADLAKMPHVLVAGTTGSGKSVGINAMILSLLYKAEARDVRLLMIDPKMLEMSV
YEGIPHLLAPVVTDMKQAAHGLNWCVAEMERRYKLMSKLGVRNLAGYNTKIDEAKAREEFIYNPFSLTPEEPEPLERLPH
IVVIIDELADLMMVVGKKIEELIARLAQKARAAGIHLILATQRPSVDVITGLIKANIPTRIAFSVGSKIDSRTILDQMGA
EALLGMGDMLYMASGTGLPIRVHGAFVSDDEVHRVVSYLKSQGEPDYIEGVLEGGTVDGDDGAFGEGGGGGEGGEKDPMY
DQAVEVVLKDRKASISYVQRKLRIGYNRSARLLEDMEKAGLVSALTASGQREVLVPHRE
>Mature_778_residues
TYSLNTLNASAGGRSAPRSMAARFGHEIGLVAGLLALVFWLLALASYSAQDAAWSTSGAHDSRLMANWAGRLGAWLADGS
YFALGFSVWWCVAAGVRAWIASLARWMRGGESATPGQSPLARRLMFWIGLALLLCASTALEWSRLYRLEPLLPGHAGGVL
GYITGPAGVKWLGFTGSGLVAVIAVVAGAALVFRFSWGQLAERLGGRIDGLVQFGRARREKARDVAAGKRAAREREEVVQ
EERHEIQEHHPQPVQIIEPVLMADAPPSARVVKERQKPLFTEMPDSRLPQVDLLDGAQARQETVAPETLEMTSRLIEKKL
KDFGVEVRVVAAMPGPVITRYEIEPATGVKGSQIVNLAKDLARSLSLVSIRVIETIPGKNYMALELPNAKRQSIRLSEIL
GSQIYHDAKSLLTMGLGKDIVGNPVVADLAKMPHVLVAGTTGSGKSVGINAMILSLLYKAEARDVRLLMIDPKMLEMSVY
EGIPHLLAPVVTDMKQAAHGLNWCVAEMERRYKLMSKLGVRNLAGYNTKIDEAKAREEFIYNPFSLTPEEPEPLERLPHI
VVIIDELADLMMVVGKKIEELIARLAQKARAAGIHLILATQRPSVDVITGLIKANIPTRIAFSVGSKIDSRTILDQMGAE
ALLGMGDMLYMASGTGLPIRVHGAFVSDDEVHRVVSYLKSQGEPDYIEGVLEGGTVDGDDGAFGEGGGGGEGGEKDPMYD
QAVEVVLKDRKASISYVQRKLRIGYNRSARLLEDMEKAGLVSALTASGQREVLVPHRE

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=498, Percent_Identity=62.2489959839357, Blast_Score=600, Evalue=1e-173,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 84531; Mature: 84400

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYSLNTLNASAGGRSAPRSMAARFGHEIGLVAGLLALVFWLLALASYSAQDAAWSTSGA
CCEECCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
HDSRLMANWAGRLGAWLADGSYFALGFSVWWCVAAGVRAWIASLARWMRGGESATPGQSP
CCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
LARRLMFWIGLALLLCASTALEWSRLYRLEPLLPGHAGGVLGYITGPAGVKWLGFTGSGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEEEECCCHH
VAVIAVVAGAALVFRFSWGQLAERLGGRIDGLVQFGRARREKARDVAAGKRAAREREEVV
HHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEERHEIQEHHPQPVQIIEPVLMADAPPSARVVKERQKPLFTEMPDSRLPQVDLLDGAQA
HHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCEEECCCCCHH
RQETVAPETLEMTSRLIEKKLKDFGVEVRVVAAMPGPVITRYEIEPATGVKGSQIVNLAK
HHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHH
DLARSLSLVSIRVIETIPGKNYMALELPNAKRQSIRLSEILGSQIYHDAKSLLTMGLGKD
HHHHHHHHHEEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IVGNPVVADLAKMPHVLVAGTTGSGKSVGINAMILSLLYKAEARDVRLLMIDPKMLEMSV
CCCCHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHH
YEGIPHLLAPVVTDMKQAAHGLNWCVAEMERRYKLMSKLGVRNLAGYNTKIDEAKAREEF
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCHHHHHHHHH
IYNPFSLTPEEPEPLERLPHIVVIIDELADLMMVVGKKIEELIARLAQKARAAGIHLILA
CCCCCCCCCCCCCHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEE
TQRPSVDVITGLIKANIPTRIAFSVGSKIDSRTILDQMGAEALLGMGDMLYMASGTGLPI
CCCCCHHHHHHHHHCCCCCEEEEHHCCCCHHHHHHHHHCHHHHHCCCCEEEEECCCCCEE
RVHGAFVSDDEVHRVVSYLKSQGEPDYIEGVLEGGTVDGDDGAFGEGGGGGEGGEKDPMY
EEEEEECCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHH
DQAVEVVLKDRKASISYVQRKLRIGYNRSARLLEDMEKAGLVSALTASGQREVLVPHRE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCC
>Mature Secondary Structure 
TYSLNTLNASAGGRSAPRSMAARFGHEIGLVAGLLALVFWLLALASYSAQDAAWSTSGA
CEECCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
HDSRLMANWAGRLGAWLADGSYFALGFSVWWCVAAGVRAWIASLARWMRGGESATPGQSP
CCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
LARRLMFWIGLALLLCASTALEWSRLYRLEPLLPGHAGGVLGYITGPAGVKWLGFTGSGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEEEECCCHH
VAVIAVVAGAALVFRFSWGQLAERLGGRIDGLVQFGRARREKARDVAAGKRAAREREEVV
HHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEERHEIQEHHPQPVQIIEPVLMADAPPSARVVKERQKPLFTEMPDSRLPQVDLLDGAQA
HHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCEEECCCCCHH
RQETVAPETLEMTSRLIEKKLKDFGVEVRVVAAMPGPVITRYEIEPATGVKGSQIVNLAK
HHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHH
DLARSLSLVSIRVIETIPGKNYMALELPNAKRQSIRLSEILGSQIYHDAKSLLTMGLGKD
HHHHHHHHHEEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IVGNPVVADLAKMPHVLVAGTTGSGKSVGINAMILSLLYKAEARDVRLLMIDPKMLEMSV
CCCCHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHH
YEGIPHLLAPVVTDMKQAAHGLNWCVAEMERRYKLMSKLGVRNLAGYNTKIDEAKAREEF
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCHHHHHHHHH
IYNPFSLTPEEPEPLERLPHIVVIIDELADLMMVVGKKIEELIARLAQKARAAGIHLILA
CCCCCCCCCCCCCHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEE
TQRPSVDVITGLIKANIPTRIAFSVGSKIDSRTILDQMGAEALLGMGDMLYMASGTGLPI
CCCCCHHHHHHHHHCCCCCEEEEHHCCCCHHHHHHHHHCHHHHHCCCCEEEEECCCCCEE
RVHGAFVSDDEVHRVVSYLKSQGEPDYIEGVLEGGTVDGDDGAFGEGGGGGEGGEKDPMY
EEEEEECCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHH
DQAVEVVLKDRKASISYVQRKLRIGYNRSARLLEDMEKAGLVSALTASGQREVLVPHRE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]