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The map label for this gene is ycfH [C]

Identifier: 120612062

GI number: 120612062

Start: 3765907

End: 3766701

Strand: Reverse

Name: ycfH [C]

Synonym: Aave_3409

Alternate gene names: 120612062

Gene position: 3766701-3765907 (Counterclockwise)

Preceding gene: 120612063

Following gene: 120612061

Centisome position: 70.37

GC content: 68.05

Gene sequence:

>795_bases
ATGTTCACCGATTCGCATTGCCACCTGAGCTTTCCCGAACTGTCCGCGCAACTGCCCGCCATCCGCCAGGCCATGGACGA
GGCGCGCGTCACCCGCGCGCTGTGCATCTGCACCACCATGGAGGAATTCGGCGACGTGCATGCGCTCGCGCTCGCCCACG
ACAACTTCTGGAGCACGGTGGGCGTGCATCCCGACAACGAGGGCGTTACCGAACCGTCGGTGCAGGACCTGCTGGACCGC
GCCGCGCTGCCCCGGGTCATCGCCATCGGCGAGACCGGGCTGGACTACTACGGCATGGAAGACCGCAAGGGCGGCCGCAG
CATCGCCGACCTGGAATGGCAGCGCGAGCGCTTCCGCACCCACATCCGCGCCGCACGGGCCTGCGGCAAGCCGCTGGTCA
TCCACACCCGCAGCGCGTCCGACGACACCCTCGCCATCCTGCGGGAGGAGGGCGAGGACGGCGCGGGCAAACGTGCGGGG
GGCGTCTTCCACTGCTTCACCGAGACGGCCGAGGTGGCACGCGCGGCGCTGGACCTCGGCTACTACATCTCGTTCTCGGG
CATCCTCACCTTCAAGAATGCCCAGTCGCTGCGCGACGTGGCGGCCTTCGTGCCGCTCGACCGCATGCTCATCGAGACCG
ACAGCCCTTACCTCGCGCCCGTGCCCTACCGGGGCAAAACCAACAACCCGTCCTACGTGCCCTTCGTGGCGCAGCAGATC
GCGGCGCTCCGGGGCATGCAGGCTGAAGCCGTGGGCGAGGCCACGAGCCGGAATTTCGACACGCTCTTTTTCTGA

Upstream 100 bases:

>100_bases
ATTCCGGGAGGAAGGCGATCCGTTCCGCAGGCCGGAACCCGGCCGTTCCGCCGTTCTCCTACGGCCGTGGCGTCCCGCGC
CGCCTAACATTCCTGCAGCC

Downstream 100 bases:

>100_bases
AAGGATGCTCCATGACGCAGCTTCGCCCCCTGTCGCGGCGCCTGTTCGTCTCCGCCGCGGCGCTGGCCGGCGCGGGCCTG
TGCGCTGCCTGCGCGCACGC

Product: TatD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MFTDSHCHLSFPELSAQLPAIRQAMDEARVTRALCICTTMEEFGDVHALALAHDNFWSTVGVHPDNEGVTEPSVQDLLDR
AALPRVIAIGETGLDYYGMEDRKGGRSIADLEWQRERFRTHIRAARACGKPLVIHTRSASDDTLAILREEGEDGAGKRAG
GVFHCFTETAEVARAALDLGYYISFSGILTFKNAQSLRDVAAFVPLDRMLIETDSPYLAPVPYRGKTNNPSYVPFVAQQI
AALRGMQAEAVGEATSRNFDTLFF

Sequences:

>Translated_264_residues
MFTDSHCHLSFPELSAQLPAIRQAMDEARVTRALCICTTMEEFGDVHALALAHDNFWSTVGVHPDNEGVTEPSVQDLLDR
AALPRVIAIGETGLDYYGMEDRKGGRSIADLEWQRERFRTHIRAARACGKPLVIHTRSASDDTLAILREEGEDGAGKRAG
GVFHCFTETAEVARAALDLGYYISFSGILTFKNAQSLRDVAAFVPLDRMLIETDSPYLAPVPYRGKTNNPSYVPFVAQQI
AALRGMQAEAVGEATSRNFDTLFF
>Mature_264_residues
MFTDSHCHLSFPELSAQLPAIRQAMDEARVTRALCICTTMEEFGDVHALALAHDNFWSTVGVHPDNEGVTEPSVQDLLDR
AALPRVIAIGETGLDYYGMEDRKGGRSIADLEWQRERFRTHIRAARACGKPLVIHTRSASDDTLAILREEGEDGAGKRAG
GVFHCFTETAEVARAALDLGYYISFSGILTFKNAQSLRDVAAFVPLDRMLIETDSPYLAPVPYRGKTNNPSYVPFVAQQI
AALRGMQAEAVGEATSRNFDTLFF

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349734, Length=277, Percent_Identity=28.8808664259928, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI110349730, Length=277, Percent_Identity=28.8808664259928, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI226061853, Length=285, Percent_Identity=29.4736842105263, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI225903424, Length=233, Percent_Identity=28.3261802575107, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI225903439, Length=179, Percent_Identity=32.4022346368715, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI14042943, Length=179, Percent_Identity=32.4022346368715, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI226061614, Length=266, Percent_Identity=25.9398496240602, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI226061595, Length=242, Percent_Identity=29.3388429752066, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI1787342, Length=267, Percent_Identity=44.9438202247191, Blast_Score=208, Evalue=3e-55,
Organism=Escherichia coli, GI48994985, Length=243, Percent_Identity=32.0987654320988, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI87082439, Length=266, Percent_Identity=28.9473684210526, Blast_Score=111, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17565396, Length=224, Percent_Identity=30.8035714285714, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17559024, Length=292, Percent_Identity=24.3150684931507, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17543026, Length=221, Percent_Identity=31.2217194570136, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71980746, Length=180, Percent_Identity=30, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24648690, Length=296, Percent_Identity=28.3783783783784, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24586117, Length=201, Percent_Identity=31.8407960199005, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI221330018, Length=201, Percent_Identity=31.8407960199005, Blast_Score=74, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29099; Mature: 29099

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS01090 TATD_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTDSHCHLSFPELSAQLPAIRQAMDEARVTRALCICTTMEEFGDVHALALAHDNFWSTV
CCCCCCCEEECHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCEEE
GVHPDNEGVTEPSVQDLLDRAALPRVIAIGETGLDYYGMEDRKGGRSIADLEWQRERFRT
CCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
HIRAARACGKPLVIHTRSASDDTLAILREEGEDGAGKRAGGVFHCFTETAEVARAALDLG
HHHHHHHCCCCEEEEECCCCCCEEEEEEECCCCCCCCCCCCEEEEHHHHHHHHHHHHHHH
YYISFSGILTFKNAQSLRDVAAFVPLDRMLIETDSPYLAPVPYRGKTNNPSYVPFVAQQI
HEEEEEEEEEECCHHHHHHHHHHCCHHHHEEECCCCEECCCCCCCCCCCCCCCHHHHHHH
AALRGMQAEAVGEATSRNFDTLFF
HHHHCCCHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MFTDSHCHLSFPELSAQLPAIRQAMDEARVTRALCICTTMEEFGDVHALALAHDNFWSTV
CCCCCCCEEECHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCEEE
GVHPDNEGVTEPSVQDLLDRAALPRVIAIGETGLDYYGMEDRKGGRSIADLEWQRERFRT
CCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
HIRAARACGKPLVIHTRSASDDTLAILREEGEDGAGKRAGGVFHCFTETAEVARAALDLG
HHHHHHHCCCCEEEEECCCCCCEEEEEEECCCCCCCCCCCCEEEEHHHHHHHHHHHHHHH
YYISFSGILTFKNAQSLRDVAAFVPLDRMLIETDSPYLAPVPYRGKTNNPSYVPFVAQQI
HEEEEEEEEEECCHHHHHHHHHHCCHHHHEEECCCCEECCCCCCCCCCCCCCCHHHHHHH
AALRGMQAEAVGEATSRNFDTLFF
HHHHCCCHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]