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The map label for this gene is pncB [H]

Identifier: 120611962

GI number: 120611962

Start: 3657617

End: 3658825

Strand: Reverse

Name: pncB [H]

Synonym: Aave_3306

Alternate gene names: 120611962

Gene position: 3658825-3657617 (Counterclockwise)

Preceding gene: 120611964

Following gene: 120611961

Centisome position: 68.35

GC content: 66.5

Gene sequence:

>1209_bases
ATGATCATCACCAGCCTGCTCGATACCGACCTGTACAAGTTCACCATGATGCAGGTGGTGCTGCACCAGTTTCCCGGAGC
GCAGGTGGAATACCGCTTCCGGTGCCGCAACCCCGGCGTGCAGCTCGCGCCGTATGCGGCCGAGATCCGCGACGAGATCC
GCTCGCTCTGCAGCCTGCAGTTCCAGGACGCGGAGCTGATGTACCTGCGCTCGCTGCGCTTCGTGAAGAGCGATTTCGTG
GACTTCCTGGGGCTGTTCCGCCTCAACGAGAAATACATCACCGTCACGCCGCTGGCCTCGGGGGAGATCGACATCCGGAT
CGCCGGGCCGTGGCTGCACACCATCCTGTTCGAGATCCCGGTGCTGGCGATCGTGAACGAGGTGTACTTCCGCAATACGC
AGAAGGTGCCGGATTTCCCCGAGGGCCGCCGCCGGCTGGACACCAAGATCGCCCAGTTGCAGGCGGACGGTCTGGGGGAG
CTGAAGATCGCCGACTACGGCACCCGGCGGCGCTTCAGCCGCGCCTGGCACGAAGAGGTGCTGCGCGTGCTGCTGGCCCG
CCTGGGCACGGGCGACCGCCGCACCGACGGCCGCGCGGGGCCCGGGCAGTTCGCGGGCACGAGCAACGTGCTCTATGCGA
TGAAGCTCGGGGTCACGCCGCTCGGCACCATGGCGCACGAATACCTGCAGGCCTGCCAGGCGCTGGGCCCGCGGTTGCGC
GACAGCCAGATCTACGGCTTCGAGATGTGGGCGCGCGAATACCGCGGCGACCTGGGCATCGCGCTGTCCGACGTTTATGG
CATGAGCGCCTTCCTGCGCGATTTCGACCTGTATTTCTGCAAGCTGTTCGACGGCGCGCGGCATGACAGCGGCGATCCGT
TCGCCTGGGGCGAGCGGCTGCTGGAGCACTACCGCCGCAACCGCGTCGATCCGCTCACCAAGACGCTGATCTTCAGCGAC
GCGCTCACGGTGCCGCGCACGATCGAGCTGTTCCGGCAGTTCCACGGGCGCTGCCAGCTCGCTTTCGGGATCGGCACCAA
CCTGACCAACGACCTGGGCTGCGAGCCGCTGCAGATCGTCATCAAGATGACGCGCTGCAACGGCCAGCCCGTGGCCAAGC
TGTCCGACACGCCCGGCAAGGGCATGTGCGACGACGAGAAATACCTCGCCTACCTGCGGCAGGTGTTCGAGATACCCGCC
CCGGCCTGA

Upstream 100 bases:

>100_bases
GCACGCGATGGCGCGCTTGGTGACACAATGCACGGCGCGCCTGCAGCTTTCCCTTCCGCGCCCCGGCCCCGCCGCCGGGC
CGCGCGCCGATGCCTCTTCC

Downstream 100 bases:

>100_bases
TCCGCCGCGCTTCGGCGCACCGCGCGTCCGTCCGTCCGTCAGTCCGCTCCACGCGGTTCGGCCCCGTCCTTCTTTCACCA
GGAATCCACGTCCATGACCC

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase [H]

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MIITSLLDTDLYKFTMMQVVLHQFPGAQVEYRFRCRNPGVQLAPYAAEIRDEIRSLCSLQFQDAELMYLRSLRFVKSDFV
DFLGLFRLNEKYITVTPLASGEIDIRIAGPWLHTILFEIPVLAIVNEVYFRNTQKVPDFPEGRRRLDTKIAQLQADGLGE
LKIADYGTRRRFSRAWHEEVLRVLLARLGTGDRRTDGRAGPGQFAGTSNVLYAMKLGVTPLGTMAHEYLQACQALGPRLR
DSQIYGFEMWAREYRGDLGIALSDVYGMSAFLRDFDLYFCKLFDGARHDSGDPFAWGERLLEHYRRNRVDPLTKTLIFSD
ALTVPRTIELFRQFHGRCQLAFGIGTNLTNDLGCEPLQIVIKMTRCNGQPVAKLSDTPGKGMCDDEKYLAYLRQVFEIPA
PA

Sequences:

>Translated_402_residues
MIITSLLDTDLYKFTMMQVVLHQFPGAQVEYRFRCRNPGVQLAPYAAEIRDEIRSLCSLQFQDAELMYLRSLRFVKSDFV
DFLGLFRLNEKYITVTPLASGEIDIRIAGPWLHTILFEIPVLAIVNEVYFRNTQKVPDFPEGRRRLDTKIAQLQADGLGE
LKIADYGTRRRFSRAWHEEVLRVLLARLGTGDRRTDGRAGPGQFAGTSNVLYAMKLGVTPLGTMAHEYLQACQALGPRLR
DSQIYGFEMWAREYRGDLGIALSDVYGMSAFLRDFDLYFCKLFDGARHDSGDPFAWGERLLEHYRRNRVDPLTKTLIFSD
ALTVPRTIELFRQFHGRCQLAFGIGTNLTNDLGCEPLQIVIKMTRCNGQPVAKLSDTPGKGMCDDEKYLAYLRQVFEIPA
PA
>Mature_402_residues
MIITSLLDTDLYKFTMMQVVLHQFPGAQVEYRFRCRNPGVQLAPYAAEIRDEIRSLCSLQFQDAELMYLRSLRFVKSDFV
DFLGLFRLNEKYITVTPLASGEIDIRIAGPWLHTILFEIPVLAIVNEVYFRNTQKVPDFPEGRRRLDTKIAQLQADGLGE
LKIADYGTRRRFSRAWHEEVLRVLLARLGTGDRRTDGRAGPGQFAGTSNVLYAMKLGVTPLGTMAHEYLQACQALGPRLR
DSQIYGFEMWAREYRGDLGIALSDVYGMSAFLRDFDLYFCKLFDGARHDSGDPFAWGERLLEHYRRNRVDPLTKTLIFSD
ALTVPRTIELFRQFHGRCQLAFGIGTNLTNDLGCEPLQIVIKMTRCNGQPVAKLSDTPGKGMCDDEKYLAYLRQVFEIPA
PA

Specific function: NAD biosynthesis; nicotinamide to NaMN; second step. [C]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family [H]

Homologues:

Organism=Escherichia coli, GI1787162, Length=403, Percent_Identity=42.1836228287841, Blast_Score=328, Evalue=4e-91,
Organism=Saccharomyces cerevisiae, GI6324783, Length=409, Percent_Identity=30.5623471882641, Blast_Score=191, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006406
- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR002638 [H]

Pfam domain/function: PF04095 NAPRTase [H]

EC number: =2.4.2.11 [H]

Molecular weight: Translated: 45850; Mature: 45850

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIITSLLDTDLYKFTMMQVVLHQFPGAQVEYRFRCRNPGVQLAPYAAEIRDEIRSLCSLQ
CEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEECHHHHHHHHHHHHHHCCC
FQDAELMYLRSLRFVKSDFVDFLGLFRLNEKYITVTPLASGEIDIRIAGPWLHTILFEIP
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECHHHHHHHHHHH
VLAIVNEVYFRNTQKVPDFPEGRRRLDTKIAQLQADGLGELKIADYGTRRRFSRAWHEEV
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHH
LRVLLARLGTGDRRTDGRAGPGQFAGTSNVLYAMKLGVTPLGTMAHEYLQACQALGPRLR
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCC
DSQIYGFEMWAREYRGDLGIALSDVYGMSAFLRDFDLYFCKLFDGARHDSGDPFAWGERL
CCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
LEHYRRNRVDPLTKTLIFSDALTVPRTIELFRQFHGRCQLAFGIGTNLTNDLGCEPLQIV
HHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHH
IKMTRCNGQPVAKLSDTPGKGMCDDEKYLAYLRQVFEIPAPA
HHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIITSLLDTDLYKFTMMQVVLHQFPGAQVEYRFRCRNPGVQLAPYAAEIRDEIRSLCSLQ
CEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEECHHHHHHHHHHHHHHCCC
FQDAELMYLRSLRFVKSDFVDFLGLFRLNEKYITVTPLASGEIDIRIAGPWLHTILFEIP
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECHHHHHHHHHHH
VLAIVNEVYFRNTQKVPDFPEGRRRLDTKIAQLQADGLGELKIADYGTRRRFSRAWHEEV
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHH
LRVLLARLGTGDRRTDGRAGPGQFAGTSNVLYAMKLGVTPLGTMAHEYLQACQALGPRLR
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCC
DSQIYGFEMWAREYRGDLGIALSDVYGMSAFLRDFDLYFCKLFDGARHDSGDPFAWGERL
CCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
LEHYRRNRVDPLTKTLIFSDALTVPRTIELFRQFHGRCQLAFGIGTNLTNDLGCEPLQIV
HHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHH
IKMTRCNGQPVAKLSDTPGKGMCDDEKYLAYLRQVFEIPAPA
HHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA