Click here to switch to the map view.

The map label for this gene is prpC [H]

Identifier: 120611901

GI number: 120611901

Start: 3579989

End: 3580792

Strand: Direct

Name: prpC [H]

Synonym: Aave_3243

Alternate gene names: 120611901

Gene position: 3579989-3580792 (Clockwise)

Preceding gene: 120611899

Following gene: 120611907

Centisome position: 66.88

GC content: 69.03

Gene sequence:

>804_bases
ATGACCAAACCGTTTCGCCTCACTGCGTCAACCGGTATCCACAAGGGCGACCGCGACTACCAGCAGGACCAGGTGGCGCT
GCTCGCGCATCCCCGGCACAACGGCTGCGTGCTCGGCGTGGTGGCCGACGGCATGGGCGGGCGCAGCGGCGGCCGCAAAG
CCTCCGACCAGGTCATGATGACCGCGCGCCAGCTCTTCGAGCGCTACGCGCCCGACAGCGACGACCCGGTCGCCATGCTC
CGGCACATGGTGGAAGAGGCGCACATCGTGATCCGCCTGACGGCCATTTCCGCGGAGCAGGAGCCCCACAGCACCGTGGC
GGCCTTCCTCATCCATCCCCGTGGCGACTGCTACTGGGCGCATGCGGGCGACTCGCGCATCTACCACTTCCGGGGCTCGC
AGCTCGTCCACCGCACCAGCGACCACTCCTACGTCCAGGCGCTGGTGGACCGTGGCGAGATCACCGAGGCCGAGGCCAAC
ACGCATCCGCACTCGAACATCCTGGTCGGGTGCCTGGGCACCGAGAGCGACCCGCCCGTGACCATCCACACCATCGCGCA
ACTGGTGCCCGGCGACGCGCTGATGGCCTGCAGCGACGGGGTGTGGCATTACTTTTCGCCCGCGGAACTCGGCTCCGTCG
TGGATTCGCTCACCCCGCGCGAAGCGACTGAGTTCCTCATCGAAAAAGCACGCACCCGCGCACGCGGAGGCGGCGATAAC
CTGTCGCTCGCCATCGTGAAGATCGAGGCGCTCGCGGAAGCCGCCCCAGGGGTGGGCGCCCGGCCCCTGCCCGCCCAGCG
CTGA

Upstream 100 bases:

>100_bases
CACAGAAAACGCGGTACATCCCTCGATAATAGGCCCCCCGGCCGCGTGCGGCCATTCCCGGCCCCACTGCCGGCTTTTCC
CTGCCCCTTCCGATACCGCT

Downstream 100 bases:

>100_bases
ACCGGGCGGATGCCGGCGGCGGCCGGGCATGCCGCGGGTCTGCCCGGTCAGCGGGCCGGCGCGGAACCGGCAGGCGCCGA
CGGGGGGGCGGGATCGGCCG

Product: protein serine/threonine phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MTKPFRLTASTGIHKGDRDYQQDQVALLAHPRHNGCVLGVVADGMGGRSGGRKASDQVMMTARQLFERYAPDSDDPVAML
RHMVEEAHIVIRLTAISAEQEPHSTVAAFLIHPRGDCYWAHAGDSRIYHFRGSQLVHRTSDHSYVQALVDRGEITEAEAN
THPHSNILVGCLGTESDPPVTIHTIAQLVPGDALMACSDGVWHYFSPAELGSVVDSLTPREATEFLIEKARTRARGGGDN
LSLAIVKIEALAEAAPGVGARPLPAQR

Sequences:

>Translated_267_residues
MTKPFRLTASTGIHKGDRDYQQDQVALLAHPRHNGCVLGVVADGMGGRSGGRKASDQVMMTARQLFERYAPDSDDPVAML
RHMVEEAHIVIRLTAISAEQEPHSTVAAFLIHPRGDCYWAHAGDSRIYHFRGSQLVHRTSDHSYVQALVDRGEITEAEAN
THPHSNILVGCLGTESDPPVTIHTIAQLVPGDALMACSDGVWHYFSPAELGSVVDSLTPREATEFLIEKARTRARGGGDN
LSLAIVKIEALAEAAPGVGARPLPAQR
>Mature_266_residues
TKPFRLTASTGIHKGDRDYQQDQVALLAHPRHNGCVLGVVADGMGGRSGGRKASDQVMMTARQLFERYAPDSDDPVAMLR
HMVEEAHIVIRLTAISAEQEPHSTVAAFLIHPRGDCYWAHAGDSRIYHFRGSQLVHRTSDHSYVQALVDRGEITEAEANT
HPHSNILVGCLGTESDPPVTIHTIAQLVPGDALMACSDGVWHYFSPAELGSVVDSLTPREATEFLIEKARTRARGGGDNL
SLAIVKIEALAEAAPGVGARPLPAQR

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 28907; Mature: 28776

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKPFRLTASTGIHKGDRDYQQDQVALLAHPRHNGCVLGVVADGMGGRSGGRKASDQVMM
CCCCEEEEECCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEECCCCCCCCCCCHHHHHHH
TARQLFERYAPDSDDPVAMLRHMVEEAHIVIRLTAISAEQEPHSTVAAFLIHPRGDCYWA
HHHHHHHHHCCCCCCHHHHHHHHHHCCEEEEEEEEECCCCCCCCEEEEEEEECCCCEEEE
HAGDSRIYHFRGSQLVHRTSDHSYVQALVDRGEITEAEANTHPHSNILVGCLGTESDPPV
ECCCCEEEEECCCEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCE
TIHTIAQLVPGDALMACSDGVWHYFSPAELGSVVDSLTPREATEFLIEKARTRARGGGDN
EHHHHHHHCCCCEEEEECCCCEEEECHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCC
LSLAIVKIEALAEAAPGVGARPLPAQR
EEEEEEEEEHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TKPFRLTASTGIHKGDRDYQQDQVALLAHPRHNGCVLGVVADGMGGRSGGRKASDQVMM
CCCEEEEECCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEECCCCCCCCCCCHHHHHHH
TARQLFERYAPDSDDPVAMLRHMVEEAHIVIRLTAISAEQEPHSTVAAFLIHPRGDCYWA
HHHHHHHHHCCCCCCHHHHHHHHHHCCEEEEEEEEECCCCCCCCEEEEEEEECCCCEEEE
HAGDSRIYHFRGSQLVHRTSDHSYVQALVDRGEITEAEANTHPHSNILVGCLGTESDPPV
ECCCCEEEEECCCEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCE
TIHTIAQLVPGDALMACSDGVWHYFSPAELGSVVDSLTPREATEFLIEKARTRARGGGDN
EHHHHHHHCCCCEEEEECCCCEEEECHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCC
LSLAIVKIEALAEAAPGVGARPLPAQR
EEEEEEEEEHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]