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The map label for this gene is acoR [H]

Identifier: 120611892

GI number: 120611892

Start: 3564031

End: 3566130

Strand: Reverse

Name: acoR [H]

Synonym: Aave_3234

Alternate gene names: 120611892

Gene position: 3566130-3564031 (Counterclockwise)

Preceding gene: 120611893

Following gene: 120611887

Centisome position: 66.62

GC content: 72.33

Gene sequence:

>2100_bases
ATGCAGAGCTCCCTCCATGGCGGGGCAGCGGCGCAGGCCGCCGCCTTCGCGCCGCTGCCTTCGGCCCGCGTCATCGCCGA
GTCGCACGAGCGCTCCCGCTCCTTCGGCCTGCACCGGCATGCATCCGCCGACCTCCAGCCCCTGGCGCCCGACGCGCTCG
CCTGGGCCGTGGCGCGCAACGACGCCCTCTGCGCACATGCGCTCCCCGTCATGGAAACCCTCTCCGCGCAGATCGCGGGT
ACGCAGAGCATGGTGCTGCTCACCGACGCCCAGGGCGTGGTGCTGCATGCCCTGGGCGACGAAGAATTCCTCGGGCGCGC
CCAGCGCGTCGCGCTGCGGCCCGGAGGCACCTGGTCCGAGCGCAGCAAGGGCACGAACGCCATCGGCACGGCCCTGGCCC
TGGGTGACGCGGTGCAGGTGAACGGCGACGAGCATTTCCTGGCCGCCAACCAGTTCCTCACCTGCTCCTGCGCGCCCATC
TGCGACCCGCTGGGCCAGGTGATCGGCGCGCTCGACGTGAGCGGTGACCGCCACCAGCAGAGCGCCCACACGCTGGCCCT
GGTGCGCATGTCCGCCCGGATGGTGGAGAACCATCTCTTCGGCAAGGTCTATGAGGACGCGGTGCGGCTGCGCTTCCATG
CGCGGCCGGAGTTCCTGGGGACGCTGGTGGAGGGGTTGGCCGCGTTCACGCCGGAGGGCCGTTTCCTCGCGGCCAACCGC
AGCGGGCAGTTCCAGCTCGGCATGTCGGCGAACGCACTGCAGGCGCAGACTTTCCCGTCGCTCTTCGGCATGCCGATGAG
CGCGCTGCTGGCCCATGCGCGCGGCGCCATGCCCAGGCCGCTGCAGCTCGCGCTGCCGGGCGGGGTGGTGGTCAACGCGA
TGGTGGAGTTCCGCCCGAAAGGGGCCGCGGCCCTCGGCTGGACGGGTCAGGGGAGCGACGAGGACACCCCGGTGCCCGGG
CCCGTGGCACCAGCTTCCGCCACGGCAAGGGCGGCCCGCAGGCCCATCGCCCCGGTACCGGCCGGCGGTCCGCGGCTGTC
CGGCCTGCGCTACCTGGACACGGGCGATGCGCAGCTGGCGCAGGTGATCGACCGCGTCTCGCGCGTGCTGGGCAGCGACG
TGCCCATGCTCATCCTCGGCGAGACCGGCACGGGCAAGGAACTGCTGGCCCGCGCCATCCACCAGGACGGCCCGCGCGCG
CGCGGGCCCTTCGTGGCGGTGAACTGCGCATCGATCCCGGAAACGCTGATCGAGGCCGAACTGTTCGGCTACGAAGAGGG
CGCCTTCACCGGCGCGCGCCGCAGGGGCAGCGTGGGCAAGATCGCCCAGGCGCACGGCGGCACGCTGTTCCTGGACGAGA
TCGGCGACATGCCCCTGGCCATGCAGGCCCGGCTGCTGCGCGTGCTGCAGGAGCGCACCGTGGCGCCGCTGGGGTCGGCG
CGACAGATCCCGGTGGACGTGCACGTGCTGTGCGCCACCCACCGCAACCTGCGCGACATGATGGTCCGGGGGCTGTTCCG
CGATGACCTGTACTACCGGCTCAACGGGCTGGTGGTGCGCCTGCCGGCCCTGCGCGAGCGTTCGGACCTGCGTGTCATCG
TGCAGCGCCTCCTGCAGGCGCAGGACCGCGAGCAGGCTGCCGAAGGCTCCACGCCGGGGTGGCAGCGACCGCGCCGGACG
GTGCCCCTGCAGGTTGCGTCCCGGGCCATGGATCTGTTCCTGCGGCACCGCTGGCCGGGCAATCTGCGCCAGCTCTCGAA
TGCGCTGCGCACGGCGGCGCTGATGGCCGGCGATGCGGACGAGATCGATATCGGGCACCTGCCGGAGGATCTGTTCGACG
AGGGCCTTCCCACAGCCGGCGATGCCGTGCCCGGGGCATCGGCGCGGGACGCCGAGCCGTCCCCGTCCGTCCGGAGTGCT
GCGCACCGGCCCGCACCGGCTGCGGTGCGCTCATGGGACGAGACCGTGGAAGATGCGCTGCGCCATGCGCTGTCGGTGCA
TGGCGGCAACGTGTCCGCCGTGGCGCGGGCGTTGGGGGTGTCGCGCAATACGGTGTACCGGCGGTTGAAATCCATGGACG
GAACGGCCGCCCATCATTGA

Upstream 100 bases:

>100_bases
GGCGGGTTTGCGCGACGGCGCCCGCCGATGGTGCTATGGTGACCGGATAACGCCCGGGCCGCGCCGAGAGCGCGAGCCGG
GGCCCTGAGGAGACAAACCC

Downstream 100 bases:

>100_bases
GGGCCGGGTGCCGGTGTCAGTCGGGCCATCGCCCGGCCCGATGCCTCGAAGCCCGCATTTTCGCCAGCGTGCCCCAGGCC
ACGCTGGCGATGGGACAGGC

Product: Fis family GAF modulated sigma54 specific transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 699; Mature: 699

Protein sequence:

>699_residues
MQSSLHGGAAAQAAAFAPLPSARVIAESHERSRSFGLHRHASADLQPLAPDALAWAVARNDALCAHALPVMETLSAQIAG
TQSMVLLTDAQGVVLHALGDEEFLGRAQRVALRPGGTWSERSKGTNAIGTALALGDAVQVNGDEHFLAANQFLTCSCAPI
CDPLGQVIGALDVSGDRHQQSAHTLALVRMSARMVENHLFGKVYEDAVRLRFHARPEFLGTLVEGLAAFTPEGRFLAANR
SGQFQLGMSANALQAQTFPSLFGMPMSALLAHARGAMPRPLQLALPGGVVVNAMVEFRPKGAAALGWTGQGSDEDTPVPG
PVAPASATARAARRPIAPVPAGGPRLSGLRYLDTGDAQLAQVIDRVSRVLGSDVPMLILGETGTGKELLARAIHQDGPRA
RGPFVAVNCASIPETLIEAELFGYEEGAFTGARRRGSVGKIAQAHGGTLFLDEIGDMPLAMQARLLRVLQERTVAPLGSA
RQIPVDVHVLCATHRNLRDMMVRGLFRDDLYYRLNGLVVRLPALRERSDLRVIVQRLLQAQDREQAAEGSTPGWQRPRRT
VPLQVASRAMDLFLRHRWPGNLRQLSNALRTAALMAGDADEIDIGHLPEDLFDEGLPTAGDAVPGASARDAEPSPSVRSA
AHRPAPAAVRSWDETVEDALRHALSVHGGNVSAVARALGVSRNTVYRRLKSMDGTAAHH

Sequences:

>Translated_699_residues
MQSSLHGGAAAQAAAFAPLPSARVIAESHERSRSFGLHRHASADLQPLAPDALAWAVARNDALCAHALPVMETLSAQIAG
TQSMVLLTDAQGVVLHALGDEEFLGRAQRVALRPGGTWSERSKGTNAIGTALALGDAVQVNGDEHFLAANQFLTCSCAPI
CDPLGQVIGALDVSGDRHQQSAHTLALVRMSARMVENHLFGKVYEDAVRLRFHARPEFLGTLVEGLAAFTPEGRFLAANR
SGQFQLGMSANALQAQTFPSLFGMPMSALLAHARGAMPRPLQLALPGGVVVNAMVEFRPKGAAALGWTGQGSDEDTPVPG
PVAPASATARAARRPIAPVPAGGPRLSGLRYLDTGDAQLAQVIDRVSRVLGSDVPMLILGETGTGKELLARAIHQDGPRA
RGPFVAVNCASIPETLIEAELFGYEEGAFTGARRRGSVGKIAQAHGGTLFLDEIGDMPLAMQARLLRVLQERTVAPLGSA
RQIPVDVHVLCATHRNLRDMMVRGLFRDDLYYRLNGLVVRLPALRERSDLRVIVQRLLQAQDREQAAEGSTPGWQRPRRT
VPLQVASRAMDLFLRHRWPGNLRQLSNALRTAALMAGDADEIDIGHLPEDLFDEGLPTAGDAVPGASARDAEPSPSVRSA
AHRPAPAAVRSWDETVEDALRHALSVHGGNVSAVARALGVSRNTVYRRLKSMDGTAAHH
>Mature_699_residues
MQSSLHGGAAAQAAAFAPLPSARVIAESHERSRSFGLHRHASADLQPLAPDALAWAVARNDALCAHALPVMETLSAQIAG
TQSMVLLTDAQGVVLHALGDEEFLGRAQRVALRPGGTWSERSKGTNAIGTALALGDAVQVNGDEHFLAANQFLTCSCAPI
CDPLGQVIGALDVSGDRHQQSAHTLALVRMSARMVENHLFGKVYEDAVRLRFHARPEFLGTLVEGLAAFTPEGRFLAANR
SGQFQLGMSANALQAQTFPSLFGMPMSALLAHARGAMPRPLQLALPGGVVVNAMVEFRPKGAAALGWTGQGSDEDTPVPG
PVAPASATARAARRPIAPVPAGGPRLSGLRYLDTGDAQLAQVIDRVSRVLGSDVPMLILGETGTGKELLARAIHQDGPRA
RGPFVAVNCASIPETLIEAELFGYEEGAFTGARRRGSVGKIAQAHGGTLFLDEIGDMPLAMQARLLRVLQERTVAPLGSA
RQIPVDVHVLCATHRNLRDMMVRGLFRDDLYYRLNGLVVRLPALRERSDLRVIVQRLLQAQDREQAAEGSTPGWQRPRRT
VPLQVASRAMDLFLRHRWPGNLRQLSNALRTAALMAGDADEIDIGHLPEDLFDEGLPTAGDAVPGASARDAEPSPSVRSA
AHRPAPAAVRSWDETVEDALRHALSVHGGNVSAVARALGVSRNTVYRRLKSMDGTAAHH

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789233, Length=342, Percent_Identity=37.719298245614, Blast_Score=227, Evalue=2e-60,
Organism=Escherichia coli, GI1790437, Length=335, Percent_Identity=38.5074626865672, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI1788905, Length=332, Percent_Identity=38.5542168674699, Blast_Score=209, Evalue=6e-55,
Organism=Escherichia coli, GI1786524, Length=344, Percent_Identity=40.1162790697674, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI1790299, Length=337, Percent_Identity=40.3560830860534, Blast_Score=203, Evalue=4e-53,
Organism=Escherichia coli, GI1788550, Length=346, Percent_Identity=35.8381502890173, Blast_Score=202, Evalue=6e-53,
Organism=Escherichia coli, GI87082117, Length=336, Percent_Identity=37.202380952381, Blast_Score=193, Evalue=3e-50,
Organism=Escherichia coli, GI87082152, Length=343, Percent_Identity=35.8600583090379, Blast_Score=178, Evalue=1e-45,
Organism=Escherichia coli, GI1789087, Length=239, Percent_Identity=41.4225941422594, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI1787583, Length=235, Percent_Identity=40, Blast_Score=171, Evalue=2e-43,
Organism=Escherichia coli, GI87081872, Length=240, Percent_Identity=38.75, Blast_Score=169, Evalue=5e-43,
Organism=Escherichia coli, GI87081858, Length=636, Percent_Identity=24.0566037735849, Blast_Score=149, Evalue=7e-37,
Organism=Escherichia coli, GI1789828, Length=302, Percent_Identity=34.1059602649007, Blast_Score=137, Evalue=3e-33,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 74457; Mature: 74457

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSSLHGGAAAQAAAFAPLPSARVIAESHERSRSFGLHRHASADLQPLAPDALAWAVARN
CCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCC
DALCAHALPVMETLSAQIAGTQSMVLLTDAQGVVLHALGDEEFLGRAQRVALRPGGTWSE
CCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCHHHHCHHHEEEECCCCCCHH
RSKGTNAIGTALALGDAVQVNGDEHFLAANQFLTCSCAPICDPLGQVIGALDVSGDRHQQ
HCCCCCHHHHHHHHCCEEEECCCCEEEECCCEEEEECCHHHHHHHHHHHHHCCCCCCHHH
SAHTLALVRMSARMVENHLFGKVYEDAVRLRFHARPEFLGTLVEGLAAFTPEGRFLAANR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEECC
SGQFQLGMSANALQAQTFPSLFGMPMSALLAHARGAMPRPLQLALPGGVVVNAMVEFRPK
CCCEEECCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEECCCCCEEEHHHHCCCC
GAAALGWTGQGSDEDTPVPGPVAPASATARAARRPIAPVPAGGPRLSGLRYLDTGDAQLA
CCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCHHHH
QVIDRVSRVLGSDVPMLILGETGTGKELLARAIHQDGPRARGPFVAVNCASIPETLIEAE
HHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHH
LFGYEEGAFTGARRRGSVGKIAQAHGGTLFLDEIGDMPLAMQARLLRVLQERTVAPLGSA
HHCCCCCCCCCHHCCCCCHHHHHHCCCEEEEHHHCCCCHHHHHHHHHHHHHHCCCCCCCC
RQIPVDVHVLCATHRNLRDMMVRGLFRDDLYYRLNGLVVRLPALRERSDLRVIVQRLLQA
CCCCCEEEEEEHHHCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHH
QDREQAAEGSTPGWQRPRRTVPLQVASRAMDLFLRHRWPGNLRQLSNALRTAALMAGDAD
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCC
EIDIGHLPEDLFDEGLPTAGDAVPGASARDAEPSPSVRSAAHRPAPAAVRSWDETVEDAL
CCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHH
RHALSVHGGNVSAVARALGVSRNTVYRRLKSMDGTAAHH
HHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MQSSLHGGAAAQAAAFAPLPSARVIAESHERSRSFGLHRHASADLQPLAPDALAWAVARN
CCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCC
DALCAHALPVMETLSAQIAGTQSMVLLTDAQGVVLHALGDEEFLGRAQRVALRPGGTWSE
CCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCHHHHCHHHEEEECCCCCCHH
RSKGTNAIGTALALGDAVQVNGDEHFLAANQFLTCSCAPICDPLGQVIGALDVSGDRHQQ
HCCCCCHHHHHHHHCCEEEECCCCEEEECCCEEEEECCHHHHHHHHHHHHHCCCCCCHHH
SAHTLALVRMSARMVENHLFGKVYEDAVRLRFHARPEFLGTLVEGLAAFTPEGRFLAANR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEECC
SGQFQLGMSANALQAQTFPSLFGMPMSALLAHARGAMPRPLQLALPGGVVVNAMVEFRPK
CCCEEECCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEECCCCCEEEHHHHCCCC
GAAALGWTGQGSDEDTPVPGPVAPASATARAARRPIAPVPAGGPRLSGLRYLDTGDAQLA
CCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCHHHH
QVIDRVSRVLGSDVPMLILGETGTGKELLARAIHQDGPRARGPFVAVNCASIPETLIEAE
HHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHH
LFGYEEGAFTGARRRGSVGKIAQAHGGTLFLDEIGDMPLAMQARLLRVLQERTVAPLGSA
HHCCCCCCCCCHHCCCCCHHHHHHCCCEEEEHHHCCCCHHHHHHHHHHHHHHCCCCCCCC
RQIPVDVHVLCATHRNLRDMMVRGLFRDDLYYRLNGLVVRLPALRERSDLRVIVQRLLQA
CCCCCEEEEEEHHHCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHH
QDREQAAEGSTPGWQRPRRTVPLQVASRAMDLFLRHRWPGNLRQLSNALRTAALMAGDAD
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCC
EIDIGHLPEDLFDEGLPTAGDAVPGASARDAEPSPSVRSAAHRPAPAAVRSWDETVEDAL
CCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHH
RHALSVHGGNVSAVARALGVSRNTVYRRLKSMDGTAAHH
HHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]