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The map label for this gene is hppA [H]

Identifier: 120611336

GI number: 120611336

Start: 2928381

End: 2930462

Strand: Reverse

Name: hppA [H]

Synonym: Aave_2668

Alternate gene names: 120611336

Gene position: 2930462-2928381 (Counterclockwise)

Preceding gene: 120611341

Following gene: 120611335

Centisome position: 54.75

GC content: 72.14

Gene sequence:

>2082_bases
ATGGCTGCATCCCCCCTCTTCCCCCCCGCACTCTGGCTGGCGTTCCTCTGCGGCGCGGCCGCCGTGGCCTACGGACTCTG
GGCGCGCCGCTGGATCCTGGCCCAGGACGCCGGCAGCGAGCGCATGCAGGCCATCGCCGCCGCGATCCAGGCCGGCGCGG
CCGCCTACCTCACTCGGCAGTACCGCACCATCGCCGTGGCGGGGGCCGTACTGGCGGTGCTCATCGGCTTCTTCCTGGAC
CTGCGCACGGCCGCCGGCTTCGCGCTGGGCGCGGCGCTATCGGGCGCCTGCGGCTTCATCGGCATGAACATCTCGGTGCG
CGCCAACGTGCGCACCGCGCAGGCGGCGGCACGGGGCATCGGCCCGGCGCTGCAGGTGGCGTTCCGCGGCGGCGCGATCA
CGGGCATGCTGGTGGTGGGCCTCGGGCTGCTGGGCGTGGCCGGCTTCGGCGCCTTCCTGCTGCATGCGGGACCGGCGGCG
CCGGGGTCCGGTGCGGGCATGGCGGCGCAGTTGCATCCGCTCATCGGATTCGCCTTCGGCGCATCGCTGATTTCCATCTT
CGCACGGCTGGGCGGCGGCATCTTCACCAAGGGCGCGGACGTGGGGGCGGACCTGGTGGGCAAGGTGGAGGCCGGCATCC
CCGAGGACGACCCGCGCAACCCGGCCGTGATCGCCGACAACGTGGGCGACAACGTCGGCGACTGCGCCGGCATGGCGGCC
GACCTGTTCGAGACCTACGCGGTGACCCTGATCGCCGCCATGGTGCTGGGCACGCTGCTCGGCATCCCGCCCGCACTGGC
CGTGGCCTACCCGCTGGCGCTGGGCGGCGTGTCGATCCTGGCCTCGATCGCGGGCTGCACCTTCGTCAAGGCGTCGCCGG
GCATGACCAACGTGATGCCTGCGCTCTACCGGGGCCTGGCCGTGGCCGGCGGGCTGTCGCTGGCGGCTTTCGCGCTGGTC
ACGTTCTGGCTGTTCCCCGATGCCGCGCTCTTTCCGCAGGCCACCGCCGGGCGGCTCTTCGGCGCCTGCGCCACGGGCCT
GGCGCTCACCGCCGCGCTGGTCTGGATCACCGAGTACTACACGGGCACGCAGTACGCACCCGTGCGCCACATCGCGCAGG
CCTCCACCACCGGGCACGGCACGAACATCATCGCGGGGCTGGGCGTGTCGATGCGCTCCACCGCCTGGCCGGTGGTGTTC
GTGTGCATGGCGATCCTGGTCTCCTACACCCTCGCGGGCATCTACGGCGTGGCGGTGGCCGCGACGGCGATGCTCAGCAT
GGCCGGCATCGTGGTCGCGCTGGACGCCTACGGCCCCATCACCGACAACGCAGGAGGCATCGCGGAGATGGCAGAACTGC
CGGCCAGCGTGCGCGCCGTGACCGATCCGCTCGACGCCGTGGGCAACACCACCAAGGCCGTCACCAAGGGCTACGCCATC
GGCTCGGCCGGCCTGGCCGCGCTGGTGCTGTTCGCCGACTACACGCACCAGCTCGGCGTGCAGGGGCAGGCGCTGCGCTT
CGACCTGTCGGATCCGCTGGTGATCGTGGGCCTGTTCATCGGCGGCCTGGTGCCCTACCTGTTCGGCGCCATGGCCATGG
AGGCCGTGGGCCGCGCGGCGGGCGCCGTGGTGGTGGAAGTGCGGCGGCAGTTCTCCACCATCGTCGGCATCATGGAAGGC
CGCGCCCAGCCCGAGTACGGCCGCGCGGTGGACATGCTCACGGCAGCCGCGATCCGCGAAATGGTGGTGCCCAGCCTGCT
GCCGGTGGCCGTGCCCATCGCGGTGGGCCTGCTGCTCGGGCCGCGCGCACTGGGCGGCCTGCTCATGGGCACCATCGTCA
CCGGACTGTTCGTGGCCACCAGCATGTGCACCGGCGGCGGCGCCTGGGACAACGCCAAGAAGTACATCGAGGACGGCCAC
CACGGCGGCAAGGGCAGCGAGGCGCACAAGGCCGCCGTCACCGGCGATACCGTGGGCGACCCCTACAAGGACACGGCCGG
GCCGGCCGTGAACCCGCTCATCAAGATCATCAACATCGTGGCGCTGCTCATCGTGCCGCTGGTGGCACGGCTGCACGGCT
GA

Upstream 100 bases:

>100_bases
CCTCGCGGGCCGATGGGCACGAGGAAGCAACGCAGCGGAAACACCCGCGATGCGTTGCGTGTTTCCTTTTCGTGCACCCC
TTTGACAGGAGACGACGAGC

Downstream 100 bases:

>100_bases
GGCTGAGCCGACGGCCCTGCGCCGCGCGACCATAGCTGCCGGCCCTGGGAGCCCGGAGACCATGGGGATGGGCCGCCCGC
AGGTGACAAGCCAGGGGCCT

Product: membrane-bound proton-translocating pyrophosphatase

Products: NA

Alternate protein names: Membrane-bound proton-translocating pyrophosphatase; Pyrophosphate-energized inorganic pyrophosphatase; H(+)-PPase [H]

Number of amino acids: Translated: 693; Mature: 692

Protein sequence:

>693_residues
MAASPLFPPALWLAFLCGAAAVAYGLWARRWILAQDAGSERMQAIAAAIQAGAAAYLTRQYRTIAVAGAVLAVLIGFFLD
LRTAAGFALGAALSGACGFIGMNISVRANVRTAQAAARGIGPALQVAFRGGAITGMLVVGLGLLGVAGFGAFLLHAGPAA
PGSGAGMAAQLHPLIGFAFGASLISIFARLGGGIFTKGADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDCAGMAA
DLFETYAVTLIAAMVLGTLLGIPPALAVAYPLALGGVSILASIAGCTFVKASPGMTNVMPALYRGLAVAGGLSLAAFALV
TFWLFPDAALFPQATAGRLFGACATGLALTAALVWITEYYTGTQYAPVRHIAQASTTGHGTNIIAGLGVSMRSTAWPVVF
VCMAILVSYTLAGIYGVAVAATAMLSMAGIVVALDAYGPITDNAGGIAEMAELPASVRAVTDPLDAVGNTTKAVTKGYAI
GSAGLAALVLFADYTHQLGVQGQALRFDLSDPLVIVGLFIGGLVPYLFGAMAMEAVGRAAGAVVVEVRRQFSTIVGIMEG
RAQPEYGRAVDMLTAAAIREMVVPSLLPVAVPIAVGLLLGPRALGGLLMGTIVTGLFVATSMCTGGGAWDNAKKYIEDGH
HGGKGSEAHKAAVTGDTVGDPYKDTAGPAVNPLIKIINIVALLIVPLVARLHG

Sequences:

>Translated_693_residues
MAASPLFPPALWLAFLCGAAAVAYGLWARRWILAQDAGSERMQAIAAAIQAGAAAYLTRQYRTIAVAGAVLAVLIGFFLD
LRTAAGFALGAALSGACGFIGMNISVRANVRTAQAAARGIGPALQVAFRGGAITGMLVVGLGLLGVAGFGAFLLHAGPAA
PGSGAGMAAQLHPLIGFAFGASLISIFARLGGGIFTKGADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDCAGMAA
DLFETYAVTLIAAMVLGTLLGIPPALAVAYPLALGGVSILASIAGCTFVKASPGMTNVMPALYRGLAVAGGLSLAAFALV
TFWLFPDAALFPQATAGRLFGACATGLALTAALVWITEYYTGTQYAPVRHIAQASTTGHGTNIIAGLGVSMRSTAWPVVF
VCMAILVSYTLAGIYGVAVAATAMLSMAGIVVALDAYGPITDNAGGIAEMAELPASVRAVTDPLDAVGNTTKAVTKGYAI
GSAGLAALVLFADYTHQLGVQGQALRFDLSDPLVIVGLFIGGLVPYLFGAMAMEAVGRAAGAVVVEVRRQFSTIVGIMEG
RAQPEYGRAVDMLTAAAIREMVVPSLLPVAVPIAVGLLLGPRALGGLLMGTIVTGLFVATSMCTGGGAWDNAKKYIEDGH
HGGKGSEAHKAAVTGDTVGDPYKDTAGPAVNPLIKIINIVALLIVPLVARLHG
>Mature_692_residues
AASPLFPPALWLAFLCGAAAVAYGLWARRWILAQDAGSERMQAIAAAIQAGAAAYLTRQYRTIAVAGAVLAVLIGFFLDL
RTAAGFALGAALSGACGFIGMNISVRANVRTAQAAARGIGPALQVAFRGGAITGMLVVGLGLLGVAGFGAFLLHAGPAAP
GSGAGMAAQLHPLIGFAFGASLISIFARLGGGIFTKGADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDCAGMAAD
LFETYAVTLIAAMVLGTLLGIPPALAVAYPLALGGVSILASIAGCTFVKASPGMTNVMPALYRGLAVAGGLSLAAFALVT
FWLFPDAALFPQATAGRLFGACATGLALTAALVWITEYYTGTQYAPVRHIAQASTTGHGTNIIAGLGVSMRSTAWPVVFV
CMAILVSYTLAGIYGVAVAATAMLSMAGIVVALDAYGPITDNAGGIAEMAELPASVRAVTDPLDAVGNTTKAVTKGYAIG
SAGLAALVLFADYTHQLGVQGQALRFDLSDPLVIVGLFIGGLVPYLFGAMAMEAVGRAAGAVVVEVRRQFSTIVGIMEGR
AQPEYGRAVDMLTAAAIREMVVPSLLPVAVPIAVGLLLGPRALGGLLMGTIVTGLFVATSMCTGGGAWDNAKKYIEDGHH
GGKGSEAHKAAVTGDTVGDPYKDTAGPAVNPLIKIINIVALLIVPLVARLHG

Specific function: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force [H]

COG id: COG3808

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004131 [H]

Pfam domain/function: PF03030 H_PPase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 69869; Mature: 69737

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAASPLFPPALWLAFLCGAAAVAYGLWARRWILAQDAGSERMQAIAAAIQAGAAAYLTRQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
YRTIAVAGAVLAVLIGFFLDLRTAAGFALGAALSGACGFIGMNISVRANVRTAQAAARGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCEEEEECCHHHHHHHHCC
GPALQVAFRGGAITGMLVVGLGLLGVAGFGAFLLHAGPAAPGSGAGMAAQLHPLIGFAFG
CHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
ASLISIFARLGGGIFTKGADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDCAGMAA
HHHHHHHHHHCCCEEECCCCCCHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHH
DLFETYAVTLIAAMVLGTLLGIPPALAVAYPLALGGVSILASIAGCTFVKASPGMTNVMP
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHH
ALYRGLAVAGGLSLAAFALVTFWLFPDAALFPQATAGRLFGACATGLALTAALVWITEYY
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TGTQYAPVRHIAQASTTGHGTNIIAGLGVSMRSTAWPVVFVCMAILVSYTLAGIYGVAVA
CCCCCHHHHHHHHHCCCCCCCCCCEECCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
ATAMLSMAGIVVALDAYGPITDNAGGIAEMAELPASVRAVTDPLDAVGNTTKAVTKGYAI
HHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHCCHHHHHHHCHHHHHCCCHHHHHHCCCC
GSAGLAALVLFADYTHQLGVQGQALRFDLSDPLVIVGLFIGGLVPYLFGAMAMEAVGRAA
CHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAVVVEVRRQFSTIVGIMEGRAQPEYGRAVDMLTAAAIREMVVPSLLPVAVPIAVGLLLG
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PRALGGLLMGTIVTGLFVATSMCTGGGAWDNAKKYIEDGHHGGKGSEAHKAAVTGDTVGD
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCHHEECCCCCCC
PYKDTAGPAVNPLIKIINIVALLIVPLVARLHG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AASPLFPPALWLAFLCGAAAVAYGLWARRWILAQDAGSERMQAIAAAIQAGAAAYLTRQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
YRTIAVAGAVLAVLIGFFLDLRTAAGFALGAALSGACGFIGMNISVRANVRTAQAAARGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCEEEEECCHHHHHHHHCC
GPALQVAFRGGAITGMLVVGLGLLGVAGFGAFLLHAGPAAPGSGAGMAAQLHPLIGFAFG
CHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
ASLISIFARLGGGIFTKGADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDCAGMAA
HHHHHHHHHHCCCEEECCCCCCHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHH
DLFETYAVTLIAAMVLGTLLGIPPALAVAYPLALGGVSILASIAGCTFVKASPGMTNVMP
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHH
ALYRGLAVAGGLSLAAFALVTFWLFPDAALFPQATAGRLFGACATGLALTAALVWITEYY
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TGTQYAPVRHIAQASTTGHGTNIIAGLGVSMRSTAWPVVFVCMAILVSYTLAGIYGVAVA
CCCCCHHHHHHHHHCCCCCCCCCCEECCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
ATAMLSMAGIVVALDAYGPITDNAGGIAEMAELPASVRAVTDPLDAVGNTTKAVTKGYAI
HHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHCCHHHHHHHCHHHHHCCCHHHHHHCCCC
GSAGLAALVLFADYTHQLGVQGQALRFDLSDPLVIVGLFIGGLVPYLFGAMAMEAVGRAA
CHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAVVVEVRRQFSTIVGIMEGRAQPEYGRAVDMLTAAAIREMVVPSLLPVAVPIAVGLLLG
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PRALGGLLMGTIVTGLFVATSMCTGGGAWDNAKKYIEDGHHGGKGSEAHKAAVTGDTVGD
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCHHEECCCCCCC
PYKDTAGPAVNPLIKIINIVALLIVPLVARLHG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA