Click here to switch to the map view.

The map label for this gene is dapD

Identifier: 120611155

GI number: 120611155

Start: 2717710

End: 2718534

Strand: Reverse

Name: dapD

Synonym: Aave_2484

Alternate gene names: 120611155

Gene position: 2718534-2717710 (Counterclockwise)

Preceding gene: 120611156

Following gene: 120611154

Centisome position: 50.79

GC content: 67.76

Gene sequence:

>825_bases
ATGACCCAACAACTGCAGAACATCATCGACACCGCCTGGGAGAACCGCGCGAGCCTCTCGCCCTCCGCCGCCCCGCGCGA
GGTGCAGGACGCCGTCGAGCACGTGATCGCCGAACTCGATGCCGGCAAGCTGCGCGTGGCCACCCGCGAGGGCGTCGGCC
AGTGGACCGTGCACCAGTGGATCAAGAAGGCCGTGCTGCTGTCGTTCCGCCTGAAGGACAACGAGCTGATCGAGGCCGGC
AGCCTCGGCTTCTACGACAAGGTTCCGACCAAGTTCGCGGGCCGTTCGGCCGCCGAGATGGCCGCCACCGGCGTGCGCGT
GGTGCCGCCGGCCGTGGCGCGCCGCGGCAGCTTCATCGCCAAGGGCGCGATCCTCATGCCCAGCTACGTGAACATCGGCG
CGTACGTGGACGAAGGCACCATGGTCGATACCTGGGCCACCGTCGGCTCCTGCGCGCAGGTGGGCAAGCACGTGCACCTG
TCCGGCGGCGTGGGCCTGGGCGGCGTGCTGGAACCCCTGCAGGCCAACCCGACCATCATCGAGGACAACTGCTTCATCGG
CGCGCGCTCGGAAATCGTCGAAGGCGTGATCGTCGAAGAGAACTCCGTCATCTCCATGGGCGTGTACATCGGCCAGAGCA
CCCCCATCTACGACCGCGCCACCGATACCGTGAGCTACGGCCGCGTGCCGGCGGGCTCGGTGGTGGTGAGCGGCAGCCTG
CCCAAGGGCGACGGCAAGTACAGCATGTACGCCGCCATCATCGTCAAGAAGGTGGACGCCAAGACCCGCTCCACCACCAG
CCTGAACGACCTGCTGCGCGACTGA

Upstream 100 bases:

>100_bases
GCGTGCGCATGGCGCTCGTGGCCGAGGTCGAGGAATGCCTCGAAGCCGCGCGCCGCATCGTGCAATTCATCCAATCCCAT
CCCTGATTCCCGAACGGACC

Downstream 100 bases:

>100_bases
CAGCCGGCGCCGCGGCCTCCGGCACCCGCCGGGCCGCGGCTACCCGCCCTTCCACCACCTTCGCAAGGGACACCCCATGA
GCACGATGGAGCGGATTCTC

Product: 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase

Products: NA

Alternate protein names: Tetrahydrodipicolinate N-succinyltransferase; THDP succinyltransferase; THP succinyltransferase; Tetrahydropicolinate succinylase

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MTQQLQNIIDTAWENRASLSPSAAPREVQDAVEHVIAELDAGKLRVATREGVGQWTVHQWIKKAVLLSFRLKDNELIEAG
SLGFYDKVPTKFAGRSAAEMAATGVRVVPPAVARRGSFIAKGAILMPSYVNIGAYVDEGTMVDTWATVGSCAQVGKHVHL
SGGVGLGGVLEPLQANPTIIEDNCFIGARSEIVEGVIVEENSVISMGVYIGQSTPIYDRATDTVSYGRVPAGSVVVSGSL
PKGDGKYSMYAAIIVKKVDAKTRSTTSLNDLLRD

Sequences:

>Translated_274_residues
MTQQLQNIIDTAWENRASLSPSAAPREVQDAVEHVIAELDAGKLRVATREGVGQWTVHQWIKKAVLLSFRLKDNELIEAG
SLGFYDKVPTKFAGRSAAEMAATGVRVVPPAVARRGSFIAKGAILMPSYVNIGAYVDEGTMVDTWATVGSCAQVGKHVHL
SGGVGLGGVLEPLQANPTIIEDNCFIGARSEIVEGVIVEENSVISMGVYIGQSTPIYDRATDTVSYGRVPAGSVVVSGSL
PKGDGKYSMYAAIIVKKVDAKTRSTTSLNDLLRD
>Mature_273_residues
TQQLQNIIDTAWENRASLSPSAAPREVQDAVEHVIAELDAGKLRVATREGVGQWTVHQWIKKAVLLSFRLKDNELIEAGS
LGFYDKVPTKFAGRSAAEMAATGVRVVPPAVARRGSFIAKGAILMPSYVNIGAYVDEGTMVDTWATVGSCAQVGKHVHLS
GGVGLGGVLEPLQANPTIIEDNCFIGARSEIVEGVIVEENSVISMGVYIGQSTPIYDRATDTVSYGRVPAGSVVVSGSLP
KGDGKYSMYAAIIVKKVDAKTRSTTSLNDLLRD

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; fourth step. [C]

COG id: COG2171

COG function: function code E; Tetrahydrodipicolinate N-succinyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family

Homologues:

Organism=Escherichia coli, GI1786362, Length=271, Percent_Identity=70.479704797048, Blast_Score=373, Evalue=1e-105,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): DAPD_ACIAC (A1TQ21)

Other databases:

- EMBL:   CP000512
- RefSeq:   YP_970833.1
- ProteinModelPortal:   A1TQ21
- SMR:   A1TQ21
- STRING:   A1TQ21
- GeneID:   4665125
- GenomeReviews:   CP000512_GR
- KEGG:   aav:Aave_2484
- NMPDR:   fig|397945.5.peg.2127
- eggNOG:   COG2171
- HOGENOM:   HBG704071
- OMA:   QWAKKAV
- PhylomeDB:   A1TQ21
- ProtClustDB:   PRK11830
- BioCyc:   AAVE397945:AAVE_2484-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00811
- InterPro:   IPR005664
- InterPro:   IPR018357
- InterPro:   IPR023180
- InterPro:   IPR011004
- Gene3D:   G3DSA:1.10.166.10
- TIGRFAMs:   TIGR00965

Pfam domain/function: SSF51161 Trimer_LpxA_like

EC number: =2.3.1.117

Molecular weight: Translated: 29176; Mature: 29044

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: BINDING 106-106 BINDING 143-143

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQQLQNIIDTAWENRASLSPSAAPREVQDAVEHVIAELDAGKLRVATREGVGQWTVHQW
CCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHH
IKKAVLLSFRLKDNELIEAGSLGFYDKVPTKFAGRSAAEMAATGVRVVPPAVARRGSFIA
HHHHHHHHEECCCCCEEECCCCCCCCCCCHHHCCCCHHHHHHCCCEECCHHHHHCCCEEE
KGAILMPSYVNIGAYVDEGTMVDTWATVGSCAQVGKHVHLSGGVGLGGVLEPLQANPTII
CCEEECCCEECCCEEECCCCEEEHHHHHHHHHHHCCEEEECCCCCCCHHHCCCCCCCCEE
EDNCFIGARSEIVEGVIVEENSVISMGVYIGQSTPIYDRATDTVSYGRVPAGSVVVSGSL
ECCCEECCHHHHHCEEEECCCCEEEEEEEECCCCCCCCCCCCCHHCCCCCCCCEEEECCC
PKGDGKYSMYAAIIVKKVDAKTRSTTSLNDLLRD
CCCCCCCEEEEEEEHHHHCCCCCCCCHHHHHHCC
>Mature Secondary Structure 
TQQLQNIIDTAWENRASLSPSAAPREVQDAVEHVIAELDAGKLRVATREGVGQWTVHQW
CHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHH
IKKAVLLSFRLKDNELIEAGSLGFYDKVPTKFAGRSAAEMAATGVRVVPPAVARRGSFIA
HHHHHHHHEECCCCCEEECCCCCCCCCCCHHHCCCCHHHHHHCCCEECCHHHHHCCCEEE
KGAILMPSYVNIGAYVDEGTMVDTWATVGSCAQVGKHVHLSGGVGLGGVLEPLQANPTII
CCEEECCCEECCCEEECCCCEEEHHHHHHHHHHHCCEEEECCCCCCCHHHCCCCCCCCEE
EDNCFIGARSEIVEGVIVEENSVISMGVYIGQSTPIYDRATDTVSYGRVPAGSVVVSGSL
ECCCEECCHHHHHCEEEECCCCEEEEEEEECCCCCCCCCCCCCHHCCCCCCCCEEEECCC
PKGDGKYSMYAAIIVKKVDAKTRSTTSLNDLLRD
CCCCCCCEEEEEEEHHHHCCCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA