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The map label for this gene is yheS [H]

Identifier: 120611151

GI number: 120611151

Start: 2712130

End: 2714160

Strand: Reverse

Name: yheS [H]

Synonym: Aave_2480

Alternate gene names: 120611151

Gene position: 2714160-2712130 (Counterclockwise)

Preceding gene: 120611152

Following gene: 120611147

Centisome position: 50.71

GC content: 68.54

Gene sequence:

>2031_bases
ATGATCCTTCTGAACAATGTCACCTTGCGCCGTGGCGCCAAGGTGTTGCTGGACAGCGCCAGCGTCACCCTCAACCCCGG
CGAGAAAGTCGGCCTCGTGGGACGCAACGGTGCCGGCAAGTCCACCCTTTTCGCGCTGCTCAACGGCTCGCTCCACGAGG
ACGGCGGCGACTTCTCGATGCCCCCCACCTGGCGCATGGCCCAGGTGGCGCAGCACATGCCCGAGACGGAGGAGTCCGCC
ACCGACTTCGTGCTGAACGGCGACACGCGCCTGAGCGCGCTGCGCGGCGAACTGCAGGCTGCGGAAGAATCCGGCGACGG
CATGGCGATCGCCCAGGCCTACGCGGACCTCGGCGATGCCGGCGAGCACGACGCCGTGCCGCGCGCCCAGGCGCTCATCC
TCGGCCTGGGCTTCAAGGTGGAAGAGCTGGGCAGGCCGGTGAACAGCTTCTCCGGTGGCTGGCGCATGCGCCTGCAGCTC
GCGCGGGCGCTCATGTGCCCGAGCGACCTGCTGCTGCTGGACGAGCCCACCAACCACCTGGACCTCGACGCCCTGGTCTG
GCTGGAAGCCTGGCTGCAGCGCTATGCCGGCACCCTGATCGTCATCAGCCACGACCGCGAGTTCCTGGACGCCATCACCA
CCGTCACGCTGCACATCGACAACGCCCGCCTGACGCGCTACGGCGGCAACTACAGTCGCTTCGAGGAACTGCGCGCCCAG
CAGATGGAACTGCAGGCCGCCAGCTATGCCAAGCAGCAGGACAAGATCGCCCACCTGCAGAAATTCATCGACCGCTTCAA
GGCCAAGGCCAGCAAGGCCAAGCAGGCCCAGAGCCGGGTCAAGGCGCTGGAGCGGATGGAGAAGATCGCCCCGGTGCTCA
TGGGCGCGGAGTTCACCTTCAGCTTCAAGGAACCCGCCAACCTGCCCAACCCGATGCTGGCGATCACCGATGCCTCCTTC
GGCTACCTGGACGAGGACGGCGGCGCCCCCAAGACCATCCTGCGCCACGTGAACCGCTCGGTCCTGGCAGGCCAGCGCAT
CGGCATCCTCGGCGCGAACGGCCAGGGCAAATCCACGCTGGTCAAGACCATCGCGCGCACCATGCGGCCGCTGGCCGGCA
GCGTGACCGAAGGCAAGGGCCTGTCCATCGGCTACTTCGCCCAGCAGGAACTCGACGTGCTGCGGCCCGCCGACAACCCG
CTGGAACACATGATCCGCCTCGCGAAGGAGCTGGGCGCCCAGTCGCGCGAGCCCAGCCGCGAGCAGGACCTGCGCAACTA
CCTCGGCACCTTCAACTTCTCGGGCGACATGGTCAAGCAGTCCGTGGGCACGATGAGCGGCGGCGAGAAGGCCCGGCTCG
TGCTGGCGATGATTGTCTGGCAGCGCCCCAACCTGCTGCTGCTCGACGAGCCGACCAACCACCTGGACCTCGCCACGCGC
GAAGCGCTGTCGATGGCGCTCAACGAGTTCGAGGGCACGGTGATGCTGGTCAGCCACGACCGGGCGCTCCTGCGCGCGGT
CTGCGACGAATTCTGGCTGGTGGGACGCGGGGCCGTAGGCCCCTTCGACGGCGACCTGGACGACTACCAGCGCTACCTGC
TCGACGAATCCAAGCGGCTGCGCGACGAGGCCCGCGCGCTGGCGTCCGCCCCGGCGGCGCCCCGGGAAGACTCAGCCGCC
CAGCCTCCCGCACCCGTGGCCCAGCCCGTGTCCGCACCTGCAGCCGCTCCCGCCGCGGCACCGAAGGATGCCCGGGAACA
ACGCAAGCTCGGGGCCCAGGCCCGGCAGCAGCTGGCAGAGAAAACCCGCCCCTTGCGGCGCGAGCTCGACCAGATCAACC
AGCGCCTGGCCGTCCTGGCCTCGGAAAAGTCCGACCTGGAGCAGCGCCTGAGCCAGCCCCTGCCCCCCGCCGAGATCGCC
GACTGCGGCCGCCGCCTCAAGGCCTGCGGGGACGAAACCGGGCAACTGGAGGAACGTTGGTTGGAACTTTCCGAATCCAT
CGAGGCCCTGGAACAAGGAGCAGACAAGTAA

Upstream 100 bases:

>100_bases
GACTGCACGCCGCAGGCCGCGCGGGCGCATTCCGCCGCATCCGCTACCATGCGCGGTTGCTTTGTCGCGGGCCCCCCGGG
CGGCCCGACGTGATTCGATC

Downstream 100 bases:

>100_bases
AATGCTGTAACGGGTCGCTGCAATTTCCTGCAAACACCGTTACAGCCCAAGACCCTCTTGCTCTTTTTTCAGGAGCAGAA
GAAAAGCCTTCGGCCGGTTG

Product: ABC transporter-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 676; Mature: 676

Protein sequence:

>676_residues
MILLNNVTLRRGAKVLLDSASVTLNPGEKVGLVGRNGAGKSTLFALLNGSLHEDGGDFSMPPTWRMAQVAQHMPETEESA
TDFVLNGDTRLSALRGELQAAEESGDGMAIAQAYADLGDAGEHDAVPRAQALILGLGFKVEELGRPVNSFSGGWRMRLQL
ARALMCPSDLLLLDEPTNHLDLDALVWLEAWLQRYAGTLIVISHDREFLDAITTVTLHIDNARLTRYGGNYSRFEELRAQ
QMELQAASYAKQQDKIAHLQKFIDRFKAKASKAKQAQSRVKALERMEKIAPVLMGAEFTFSFKEPANLPNPMLAITDASF
GYLDEDGGAPKTILRHVNRSVLAGQRIGILGANGQGKSTLVKTIARTMRPLAGSVTEGKGLSIGYFAQQELDVLRPADNP
LEHMIRLAKELGAQSREPSREQDLRNYLGTFNFSGDMVKQSVGTMSGGEKARLVLAMIVWQRPNLLLLDEPTNHLDLATR
EALSMALNEFEGTVMLVSHDRALLRAVCDEFWLVGRGAVGPFDGDLDDYQRYLLDESKRLRDEARALASAPAAPREDSAA
QPPAPVAQPVSAPAAAPAAAPKDAREQRKLGAQARQQLAEKTRPLRRELDQINQRLAVLASEKSDLEQRLSQPLPPAEIA
DCGRRLKACGDETGQLEERWLELSESIEALEQGADK

Sequences:

>Translated_676_residues
MILLNNVTLRRGAKVLLDSASVTLNPGEKVGLVGRNGAGKSTLFALLNGSLHEDGGDFSMPPTWRMAQVAQHMPETEESA
TDFVLNGDTRLSALRGELQAAEESGDGMAIAQAYADLGDAGEHDAVPRAQALILGLGFKVEELGRPVNSFSGGWRMRLQL
ARALMCPSDLLLLDEPTNHLDLDALVWLEAWLQRYAGTLIVISHDREFLDAITTVTLHIDNARLTRYGGNYSRFEELRAQ
QMELQAASYAKQQDKIAHLQKFIDRFKAKASKAKQAQSRVKALERMEKIAPVLMGAEFTFSFKEPANLPNPMLAITDASF
GYLDEDGGAPKTILRHVNRSVLAGQRIGILGANGQGKSTLVKTIARTMRPLAGSVTEGKGLSIGYFAQQELDVLRPADNP
LEHMIRLAKELGAQSREPSREQDLRNYLGTFNFSGDMVKQSVGTMSGGEKARLVLAMIVWQRPNLLLLDEPTNHLDLATR
EALSMALNEFEGTVMLVSHDRALLRAVCDEFWLVGRGAVGPFDGDLDDYQRYLLDESKRLRDEARALASAPAAPREDSAA
QPPAPVAQPVSAPAAAPAAAPKDAREQRKLGAQARQQLAEKTRPLRRELDQINQRLAVLASEKSDLEQRLSQPLPPAEIA
DCGRRLKACGDETGQLEERWLELSESIEALEQGADK
>Mature_676_residues
MILLNNVTLRRGAKVLLDSASVTLNPGEKVGLVGRNGAGKSTLFALLNGSLHEDGGDFSMPPTWRMAQVAQHMPETEESA
TDFVLNGDTRLSALRGELQAAEESGDGMAIAQAYADLGDAGEHDAVPRAQALILGLGFKVEELGRPVNSFSGGWRMRLQL
ARALMCPSDLLLLDEPTNHLDLDALVWLEAWLQRYAGTLIVISHDREFLDAITTVTLHIDNARLTRYGGNYSRFEELRAQ
QMELQAASYAKQQDKIAHLQKFIDRFKAKASKAKQAQSRVKALERMEKIAPVLMGAEFTFSFKEPANLPNPMLAITDASF
GYLDEDGGAPKTILRHVNRSVLAGQRIGILGANGQGKSTLVKTIARTMRPLAGSVTEGKGLSIGYFAQQELDVLRPADNP
LEHMIRLAKELGAQSREPSREQDLRNYLGTFNFSGDMVKQSVGTMSGGEKARLVLAMIVWQRPNLLLLDEPTNHLDLATR
EALSMALNEFEGTVMLVSHDRALLRAVCDEFWLVGRGAVGPFDGDLDDYQRYLLDESKRLRDEARALASAPAAPREDSAA
QPPAPVAQPVSAPAAAPAAAPKDAREQRKLGAQARQQLAEKTRPLRRELDQINQRLAVLASEKSDLEQRLSQPLPPAEIA
DCGRRLKACGDETGQLEERWLELSESIEALEQGADK

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=549, Percent_Identity=36.247723132969, Blast_Score=329, Evalue=7e-90,
Organism=Homo sapiens, GI10947137, Length=533, Percent_Identity=33.2082551594747, Blast_Score=307, Evalue=2e-83,
Organism=Homo sapiens, GI27881506, Length=533, Percent_Identity=33.2082551594747, Blast_Score=307, Evalue=2e-83,
Organism=Homo sapiens, GI10947135, Length=550, Percent_Identity=35.4545454545455, Blast_Score=277, Evalue=3e-74,
Organism=Homo sapiens, GI69354671, Length=550, Percent_Identity=35.2727272727273, Blast_Score=276, Evalue=3e-74,
Organism=Escherichia coli, GI1789751, Length=680, Percent_Identity=46.6176470588235, Blast_Score=586, Evalue=1e-168,
Organism=Escherichia coli, GI1787041, Length=541, Percent_Identity=34.1959334565619, Blast_Score=308, Evalue=8e-85,
Organism=Escherichia coli, GI1787182, Length=530, Percent_Identity=30.7547169811321, Blast_Score=210, Evalue=3e-55,
Organism=Escherichia coli, GI2367384, Length=544, Percent_Identity=29.9632352941176, Blast_Score=206, Evalue=5e-54,
Organism=Escherichia coli, GI1788165, Length=187, Percent_Identity=31.0160427807487, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI87081782, Length=206, Percent_Identity=29.6116504854369, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1787758, Length=193, Percent_Identity=30.0518134715026, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1786803, Length=196, Percent_Identity=29.5918367346939, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1786398, Length=203, Percent_Identity=28.0788177339901, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI87081709, Length=207, Percent_Identity=24.1545893719807, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786345, Length=224, Percent_Identity=29.0178571428571, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1788506, Length=229, Percent_Identity=22.707423580786, Blast_Score=63, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=544, Percent_Identity=38.9705882352941, Blast_Score=357, Evalue=2e-98,
Organism=Caenorhabditis elegans, GI17559834, Length=564, Percent_Identity=32.9787234042553, Blast_Score=299, Evalue=3e-81,
Organism=Caenorhabditis elegans, GI17555318, Length=549, Percent_Identity=33.3333333333333, Blast_Score=288, Evalue=5e-78,
Organism=Caenorhabditis elegans, GI193208177, Length=229, Percent_Identity=25.3275109170306, Blast_Score=69, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI25146777, Length=231, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI115533592, Length=254, Percent_Identity=25.9842519685039, Blast_Score=65, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6321121, Length=547, Percent_Identity=35.1005484460695, Blast_Score=326, Evalue=7e-90,
Organism=Saccharomyces cerevisiae, GI6320874, Length=547, Percent_Identity=33.27239488117, Blast_Score=298, Evalue=1e-81,
Organism=Saccharomyces cerevisiae, GI6325030, Length=392, Percent_Identity=32.9081632653061, Blast_Score=165, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6323278, Length=391, Percent_Identity=27.6214833759591, Blast_Score=138, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6324314, Length=391, Percent_Identity=27.6214833759591, Blast_Score=138, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24666836, Length=544, Percent_Identity=40.625, Blast_Score=388, Evalue=1e-108,
Organism=Drosophila melanogaster, GI24642252, Length=542, Percent_Identity=34.1328413284133, Blast_Score=317, Evalue=1e-86,
Organism=Drosophila melanogaster, GI18859989, Length=542, Percent_Identity=34.1328413284133, Blast_Score=317, Evalue=1e-86,
Organism=Drosophila melanogaster, GI24641342, Length=557, Percent_Identity=31.9569120287253, Blast_Score=287, Evalue=1e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 74027; Mature: 74027

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILLNNVTLRRGAKVLLDSASVTLNPGEKVGLVGRNGAGKSTLFALLNGSLHEDGGDFSM
CEEECCCHHHCCCEEEEECCCEEECCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCC
PPTWRMAQVAQHMPETEESATDFVLNGDTRLSALRGELQAAEESGDGMAIAQAYADLGDA
CCCHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCC
GEHDAVPRAQALILGLGFKVEELGRPVNSFSGGWRMRLQLARALMCPSDLLLLDEPTNHL
CCCCCCCHHHHHHHCCCCCHHHHCCCHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCCC
DLDALVWLEAWLQRYAGTLIVISHDREFLDAITTVTLHIDNARLTRYGGNYSRFEELRAQ
CHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHEEEEEECCCEEEECCCCHHHHHHHHHH
QMELQAASYAKQQDKIAHLQKFIDRFKAKASKAKQAQSRVKALERMEKIAPVLMGAEFTF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
SFKEPANLPNPMLAITDASFGYLDEDGGAPKTILRHVNRSVLAGQRIGILGANGQGKSTL
ECCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHH
VKTIARTMRPLAGSVTEGKGLSIGYFAQQELDVLRPADNPLEHMIRLAKELGAQSREPSR
HHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCH
EQDLRNYLGTFNFSGDMVKQSVGTMSGGEKARLVLAMIVWQRPNLLLLDEPTNHLDLATR
HHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHH
EALSMALNEFEGTVMLVSHDRALLRAVCDEFWLVGRGAVGPFDGDLDDYQRYLLDESKRL
HHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
RDEARALASAPAAPREDSAAQPPAPVAQPVSAPAAAPAAAPKDAREQRKLGAQARQQLAE
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
KTRPLRRELDQINQRLAVLASEKSDLEQRLSQPLPPAEIADCGRRLKACGDETGQLEERW
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHH
LELSESIEALEQGADK
HHHHHHHHHHHCCCCC
>Mature Secondary Structure
MILLNNVTLRRGAKVLLDSASVTLNPGEKVGLVGRNGAGKSTLFALLNGSLHEDGGDFSM
CEEECCCHHHCCCEEEEECCCEEECCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCC
PPTWRMAQVAQHMPETEESATDFVLNGDTRLSALRGELQAAEESGDGMAIAQAYADLGDA
CCCHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCC
GEHDAVPRAQALILGLGFKVEELGRPVNSFSGGWRMRLQLARALMCPSDLLLLDEPTNHL
CCCCCCCHHHHHHHCCCCCHHHHCCCHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCCC
DLDALVWLEAWLQRYAGTLIVISHDREFLDAITTVTLHIDNARLTRYGGNYSRFEELRAQ
CHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHEEEEEECCCEEEECCCCHHHHHHHHHH
QMELQAASYAKQQDKIAHLQKFIDRFKAKASKAKQAQSRVKALERMEKIAPVLMGAEFTF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
SFKEPANLPNPMLAITDASFGYLDEDGGAPKTILRHVNRSVLAGQRIGILGANGQGKSTL
ECCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHH
VKTIARTMRPLAGSVTEGKGLSIGYFAQQELDVLRPADNPLEHMIRLAKELGAQSREPSR
HHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCH
EQDLRNYLGTFNFSGDMVKQSVGTMSGGEKARLVLAMIVWQRPNLLLLDEPTNHLDLATR
HHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHH
EALSMALNEFEGTVMLVSHDRALLRAVCDEFWLVGRGAVGPFDGDLDDYQRYLLDESKRL
HHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
RDEARALASAPAAPREDSAAQPPAPVAQPVSAPAAAPAAAPKDAREQRKLGAQARQQLAE
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
KTRPLRRELDQINQRLAVLASEKSDLEQRLSQPLPPAEIADCGRRLKACGDETGQLEERW
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHH
LELSESIEALEQGADK
HHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]