Click here to switch to the map view.

The map label for this gene is dctS [H]

Identifier: 120611132

GI number: 120611132

Start: 2683831

End: 2686404

Strand: Reverse

Name: dctS [H]

Synonym: Aave_2461

Alternate gene names: 120611132

Gene position: 2686404-2683831 (Counterclockwise)

Preceding gene: 120611136

Following gene: 120611131

Centisome position: 50.19

GC content: 68.69

Gene sequence:

>2574_bases
ATGGACCGCCCTTCCCCCGTGCCCGCCGTCCCGGCGGAGCCTTCCGTGGTCACCGCGCCGGCCCGCTGGTGGCGCACCTG
GTGGCGCAGCCTTTCTCCTACCCGGCAAGACCGCCTGGCGGCTCTGGCGCCGCTGGCTGCCGTGCTCATGTTCCTCGCCG
CGATCGTGGCGGCCTTCTGGTATCTGCGCGCCGAAGAAGGCGAGCGCGAACAGGAGGCGCTGCGCCGCGACGTCGAGTAC
GCGCAGCAACGCGTGCGCCTGCGCCTGCTGGAGCGCCAGGAGCAGATCATGCGCATCGCGCGCGACCTCTCCAACCAGGA
TCTCGAACGCGCGGACTTCGTGTCCCGCGCGGAAGGGCTGATCAGCCAGTACCCCGAACTGCAGGCCATCACCTGGATCG
ACGACCACCGCCGTATCCGGGCCAGCCATGCGGCGCCCACGCTGCCCAGCAGCCAGTTGCGCGTGGCGGGCGAAGTACTG
CGCAATGGCGACACGGCCGACACCTTCGGCATCGCACGCGACCTGCAGCAGCCCGTGTACGCGCAGCCGCTGGCCGACCC
GGGACGGGGCGAGGCCGCGCCCCTGCTGCAGTTGCAGGTGCCCCTCGTGGCGCAGGGCAAGTTCACGGGCGTGGTGCTGG
CCGAATATTCGGTGGACAGCCTGCTGCGCTACGGCACGCCCACCGAAGTGCTCGCGCGCTACGCGGTCACGATGCTCGAC
GGCCGCGCCCAGTTGCTGGCCGGCACGCCGCTGCCGCCGCGCGGGCGCGCTTCGCCCTGGCAGCCCTGGGCCACCCGCGC
CAACCAGTACGAAGTGTTCGTGTCCCCCGTGGGCAACGGCCTCGTGCTGCGCGCACAGGCCTACCGCACTTCCCTGGGGG
TGGTGGGCAGCGGCCTCTTCTGGCTCGTGGGCACGTTGAGCGCCATGACGGCCTGGATGCTGATCGCCAACTGGCGCCAC
ACCCGCCGCCGCCTGCGCACGCAGGAGGCACTGGTGGCCGAAACCAACTTCCGCCGCGCGATGGAAAACTCCATGGTCAC
CGGCATGCGCGCGCTCGACATGAACGGCCGCATGACCTACGTGAACGCCGCCTTCTGCCAGATGACCGGCTGGAACGCGG
AGGACCTGATCGGCCAGTCCCCGCCCTACACCTACTGGCCGGAAGCCGACCACGAAGTGCTGCATTCGAAGCTGCGCGAC
GAGCTCAGCGGCAAGCAGACGGTCGGGGGCTTCCAGGTGCGGGTGAAACGCAAGAACGGCACGCTCTTCGACGCGCGGCT
GTACGTGTCGCCGCTCATCGACGCTCACGGGCAGCAGACCGGCTGGATGACCTCGATGACCGACATCACCGAGCCCAACC
GCGTGCGCGAACAGCTCACGGCGTCCCATGAGCGCTTCACCATCGTGCTGGAATCGCTGGACGCCTCCGTCTCCGTCGCG
CCCCTGGGCAGCGAGGAGCTGCTCTTCGCGAACAAGCTGTACCGCCAGTGGTTCGGCTCGCAGACCGGCGGGCACCTGCA
GCTCGTCGCCCAGGCGGGCGTCCTGCCGGCCGGCAGCTCCAGCGCGGGCAGCATGGACGACGAGGACGCCCTCATGGGCC
TGCCCACCGATACGCTCATCGACGCGCGCTCGGAGAACGCCGAGATCTACCTGCCCGACCTCGGCAAATGGCTGGAAGTG
CGCTCCCGCTACCTGAACTGGGTGGACGGCCGCCTGGCCCAGATGGTGATCGCCACCGACATCACCCCGCGCCGCCAGGC
CGAGGAGCAGGCCGCGCGCCAGGCCGAGCGCGCGCAGTCGGTGAGCCGCCTGATCACCATGGGCGAGATGGCCTCCAGCG
TGGCGCACGAGCTGAACCAGCCGCTCACGGCCATCAGCAACTATTGCAGCGGCATGGTTTCGCGCATCAAGAGCCAGCAG
ATCACGGAGGACGCCCTCCTCTCCGCGCTGGAGAAAACAGCGCACCAGGCGCAGCGCGCGGGCCAGATCATCCAGCGCAT
CCGCGCGTTCGTGAAGAAGAGCGAACCCAACCGCACCCTCGCCGACGTCCAGCACATGGTCAGCGAGGCAGTGGAACTCG
CGGACATCGAGCTGCGCAGGCACAACGTGCGTCTCACCCACTACGTGGCCGCGCGCCTGCCGCCCGTGATGGCCGACACC
ATCCTGATCGAGCAGGTGCTCATCAACCTCATGAAGAACGGCGCGGAATCCATCCAGCAGGCCGGGCGCCCGCCAGCCCG
CCGCAGTGTGGAACTGCGCGTGGTGCCGCGCCCGCTGGACAGCCAGGACGGCATCGAATTCGCGGTGCAGGACACCGGCA
AGGGACTGGCCCCGGAAGTGCTGGAACACCTCTTCGAGGCCTTCTTCTCCACCAAGCAGGAAGGCATGGGCATCGGCCTG
AACCTGTGCCGCAGCATCGTGGAATCGCACCAGGGCCGCATGCAGGCGGAGAACATCTACAATGGCCCGGAGGTCACCGG
CTGCCGATTCTCCTTCTGGCTTCCGCTCGCCCAGCCTGCGGATGACACTACGAATTCTGTAGCAAAAGCATCTACCCCAA
GGACTCCCGCATGA

Upstream 100 bases:

>100_bases
ACATTTCGAATGGCGCGCTCCAACACCACAATATGAAAAAATGCTGCACCCGCACATTCCCCCATCCGGCGGTCCCGGGC
GCTCCCCTACACTCCCCGGC

Downstream 100 bases:

>100_bases
GTTTGACTCCCAAAAAAGGTACTGTCTACGTCGTGGACGACGACGAGGCCGTGCGCGACTCGCTGCAATGGCTGCTGGAG
GGCAAGGACTACCGCGTCCG

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 857; Mature: 857

Protein sequence:

>857_residues
MDRPSPVPAVPAEPSVVTAPARWWRTWWRSLSPTRQDRLAALAPLAAVLMFLAAIVAAFWYLRAEEGEREQEALRRDVEY
AQQRVRLRLLERQEQIMRIARDLSNQDLERADFVSRAEGLISQYPELQAITWIDDHRRIRASHAAPTLPSSQLRVAGEVL
RNGDTADTFGIARDLQQPVYAQPLADPGRGEAAPLLQLQVPLVAQGKFTGVVLAEYSVDSLLRYGTPTEVLARYAVTMLD
GRAQLLAGTPLPPRGRASPWQPWATRANQYEVFVSPVGNGLVLRAQAYRTSLGVVGSGLFWLVGTLSAMTAWMLIANWRH
TRRRLRTQEALVAETNFRRAMENSMVTGMRALDMNGRMTYVNAAFCQMTGWNAEDLIGQSPPYTYWPEADHEVLHSKLRD
ELSGKQTVGGFQVRVKRKNGTLFDARLYVSPLIDAHGQQTGWMTSMTDITEPNRVREQLTASHERFTIVLESLDASVSVA
PLGSEELLFANKLYRQWFGSQTGGHLQLVAQAGVLPAGSSSAGSMDDEDALMGLPTDTLIDARSENAEIYLPDLGKWLEV
RSRYLNWVDGRLAQMVIATDITPRRQAEEQAARQAERAQSVSRLITMGEMASSVAHELNQPLTAISNYCSGMVSRIKSQQ
ITEDALLSALEKTAHQAQRAGQIIQRIRAFVKKSEPNRTLADVQHMVSEAVELADIELRRHNVRLTHYVAARLPPVMADT
ILIEQVLINLMKNGAESIQQAGRPPARRSVELRVVPRPLDSQDGIEFAVQDTGKGLAPEVLEHLFEAFFSTKQEGMGIGL
NLCRSIVESHQGRMQAENIYNGPEVTGCRFSFWLPLAQPADDTTNSVAKASTPRTPA

Sequences:

>Translated_857_residues
MDRPSPVPAVPAEPSVVTAPARWWRTWWRSLSPTRQDRLAALAPLAAVLMFLAAIVAAFWYLRAEEGEREQEALRRDVEY
AQQRVRLRLLERQEQIMRIARDLSNQDLERADFVSRAEGLISQYPELQAITWIDDHRRIRASHAAPTLPSSQLRVAGEVL
RNGDTADTFGIARDLQQPVYAQPLADPGRGEAAPLLQLQVPLVAQGKFTGVVLAEYSVDSLLRYGTPTEVLARYAVTMLD
GRAQLLAGTPLPPRGRASPWQPWATRANQYEVFVSPVGNGLVLRAQAYRTSLGVVGSGLFWLVGTLSAMTAWMLIANWRH
TRRRLRTQEALVAETNFRRAMENSMVTGMRALDMNGRMTYVNAAFCQMTGWNAEDLIGQSPPYTYWPEADHEVLHSKLRD
ELSGKQTVGGFQVRVKRKNGTLFDARLYVSPLIDAHGQQTGWMTSMTDITEPNRVREQLTASHERFTIVLESLDASVSVA
PLGSEELLFANKLYRQWFGSQTGGHLQLVAQAGVLPAGSSSAGSMDDEDALMGLPTDTLIDARSENAEIYLPDLGKWLEV
RSRYLNWVDGRLAQMVIATDITPRRQAEEQAARQAERAQSVSRLITMGEMASSVAHELNQPLTAISNYCSGMVSRIKSQQ
ITEDALLSALEKTAHQAQRAGQIIQRIRAFVKKSEPNRTLADVQHMVSEAVELADIELRRHNVRLTHYVAARLPPVMADT
ILIEQVLINLMKNGAESIQQAGRPPARRSVELRVVPRPLDSQDGIEFAVQDTGKGLAPEVLEHLFEAFFSTKQEGMGIGL
NLCRSIVESHQGRMQAENIYNGPEVTGCRFSFWLPLAQPADDTTNSVAKASTPRTPA
>Mature_857_residues
MDRPSPVPAVPAEPSVVTAPARWWRTWWRSLSPTRQDRLAALAPLAAVLMFLAAIVAAFWYLRAEEGEREQEALRRDVEY
AQQRVRLRLLERQEQIMRIARDLSNQDLERADFVSRAEGLISQYPELQAITWIDDHRRIRASHAAPTLPSSQLRVAGEVL
RNGDTADTFGIARDLQQPVYAQPLADPGRGEAAPLLQLQVPLVAQGKFTGVVLAEYSVDSLLRYGTPTEVLARYAVTMLD
GRAQLLAGTPLPPRGRASPWQPWATRANQYEVFVSPVGNGLVLRAQAYRTSLGVVGSGLFWLVGTLSAMTAWMLIANWRH
TRRRLRTQEALVAETNFRRAMENSMVTGMRALDMNGRMTYVNAAFCQMTGWNAEDLIGQSPPYTYWPEADHEVLHSKLRD
ELSGKQTVGGFQVRVKRKNGTLFDARLYVSPLIDAHGQQTGWMTSMTDITEPNRVREQLTASHERFTIVLESLDASVSVA
PLGSEELLFANKLYRQWFGSQTGGHLQLVAQAGVLPAGSSSAGSMDDEDALMGLPTDTLIDARSENAEIYLPDLGKWLEV
RSRYLNWVDGRLAQMVIATDITPRRQAEEQAARQAERAQSVSRLITMGEMASSVAHELNQPLTAISNYCSGMVSRIKSQQ
ITEDALLSALEKTAHQAQRAGQIIQRIRAFVKKSEPNRTLADVQHMVSEAVELADIELRRHNVRLTHYVAARLPPVMADT
ILIEQVLINLMKNGAESIQQAGRPPARRSVELRVVPRPLDSQDGIEFAVQDTGKGLAPEVLEHLFEAFFSTKQEGMGIGL
NLCRSIVESHQGRMQAENIYNGPEVTGCRFSFWLPLAQPADDTTNSVAKASTPRTPA

Specific function: Member of the two-component regulatory system dctS/dctR involved in the transport of C4-dicarboxylates. DctS functions as a membrane-associated protein kinase that phosphorylates dctR in response to environmental signals [H]

COG id: COG2202

COG function: function code T; FOG: PAS/PAC domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=238, Percent_Identity=26.890756302521, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI1788549, Length=300, Percent_Identity=27, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1790300, Length=281, Percent_Identity=23.4875444839858, Blast_Score=73, Evalue=8e-14,
Organism=Escherichia coli, GI1790346, Length=247, Percent_Identity=24.2914979757085, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 95286; Mature: 95286

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRPSPVPAVPAEPSVVTAPARWWRTWWRSLSPTRQDRLAALAPLAAVLMFLAAIVAAFW
CCCCCCCCCCCCCCCEEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YLRAEEGEREQEALRRDVEYAQQRVRLRLLERQEQIMRIARDLSNQDLERADFVSRAEGL
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ISQYPELQAITWIDDHRRIRASHAAPTLPSSQLRVAGEVLRNGDTADTFGIARDLQQPVY
HHHCCCCEEEEEECCHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCHH
AQPLADPGRGEAAPLLQLQVPLVAQGKFTGVVLAEYSVDSLLRYGTPTEVLARYAVTMLD
HCCCCCCCCCCCCCEEEEECCEEECCCCCEEEEEHHCHHHHHHCCCCHHHHHHHHHHHHC
GRAQLLAGTPLPPRGRASPWQPWATRANQYEVFVSPVGNGLVLRAQAYRTSLGVVGSGLF
CCHHEEECCCCCCCCCCCCCCHHHCCCCCEEEEEEECCCCEEEEEHHHHHHHHHHHHHHH
WLVGTLSAMTAWMLIANWRHTRRRLRTQEALVAETNFRRAMENSMVTGMRALDMNGRMTY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEE
VNAAFCQMTGWNAEDLIGQSPPYTYWPEADHEVLHSKLRDELSGKQTVGGFQVRVKRKNG
EEHHHHHCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCC
TLFDARLYVSPLIDAHGQQTGWMTSMTDITEPNRVREQLTASHERFTIVLESLDASVSVA
CEEEHHHHHHHHHHCCCCCCCCEECHHHCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEE
PLGSEELLFANKLYRQWFGSQTGGHLQLVAQAGVLPAGSSSAGSMDDEDALMGLPTDTLI
CCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEECCCCHHHH
DARSENAEIYLPDLGKWLEVRSRYLNWVDGRLAQMVIATDITPRRQAEEQAARQAERAQS
CCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
VSRLITMGEMASSVAHELNQPLTAISNYCSGMVSRIKSQQITEDALLSALEKTAHQAQRA
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
GQIIQRIRAFVKKSEPNRTLADVQHMVSEAVELADIELRRHNVRLTHYVAARLPPVMADT
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEHHHHHHHHCCHHHHHH
ILIEQVLINLMKNGAESIQQAGRPPARRSVELRVVPRPLDSQDGIEFAVQDTGKGLAPEV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCHHH
LEHLFEAFFSTKQEGMGIGLNLCRSIVESHQGRMQAENIYNGPEVTGCRFSFWLPLAQPA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEHHHCCCCCCCCCEEEEEECCCCCCC
DDTTNSVAKASTPRTPA
CCCHHHHHHCCCCCCCC
>Mature Secondary Structure
MDRPSPVPAVPAEPSVVTAPARWWRTWWRSLSPTRQDRLAALAPLAAVLMFLAAIVAAFW
CCCCCCCCCCCCCCCEEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YLRAEEGEREQEALRRDVEYAQQRVRLRLLERQEQIMRIARDLSNQDLERADFVSRAEGL
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ISQYPELQAITWIDDHRRIRASHAAPTLPSSQLRVAGEVLRNGDTADTFGIARDLQQPVY
HHHCCCCEEEEEECCHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCHH
AQPLADPGRGEAAPLLQLQVPLVAQGKFTGVVLAEYSVDSLLRYGTPTEVLARYAVTMLD
HCCCCCCCCCCCCCEEEEECCEEECCCCCEEEEEHHCHHHHHHCCCCHHHHHHHHHHHHC
GRAQLLAGTPLPPRGRASPWQPWATRANQYEVFVSPVGNGLVLRAQAYRTSLGVVGSGLF
CCHHEEECCCCCCCCCCCCCCHHHCCCCCEEEEEEECCCCEEEEEHHHHHHHHHHHHHHH
WLVGTLSAMTAWMLIANWRHTRRRLRTQEALVAETNFRRAMENSMVTGMRALDMNGRMTY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEE
VNAAFCQMTGWNAEDLIGQSPPYTYWPEADHEVLHSKLRDELSGKQTVGGFQVRVKRKNG
EEHHHHHCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCC
TLFDARLYVSPLIDAHGQQTGWMTSMTDITEPNRVREQLTASHERFTIVLESLDASVSVA
CEEEHHHHHHHHHHCCCCCCCCEECHHHCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEE
PLGSEELLFANKLYRQWFGSQTGGHLQLVAQAGVLPAGSSSAGSMDDEDALMGLPTDTLI
CCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEECCCCHHHH
DARSENAEIYLPDLGKWLEVRSRYLNWVDGRLAQMVIATDITPRRQAEEQAARQAERAQS
CCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
VSRLITMGEMASSVAHELNQPLTAISNYCSGMVSRIKSQQITEDALLSALEKTAHQAQRA
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
GQIIQRIRAFVKKSEPNRTLADVQHMVSEAVELADIELRRHNVRLTHYVAARLPPVMADT
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEHHHHHHHHCCHHHHHH
ILIEQVLINLMKNGAESIQQAGRPPARRSVELRVVPRPLDSQDGIEFAVQDTGKGLAPEV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCHHH
LEHLFEAFFSTKQEGMGIGLNLCRSIVESHQGRMQAENIYNGPEVTGCRFSFWLPLAQPA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEHHHCCCCCCCCCEEEEEECCCCCCC
DDTTNSVAKASTPRTPA
CCCHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8455557 [H]