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The map label for this gene is nifU [H]

Identifier: 120611115

GI number: 120611115

Start: 2669214

End: 2669612

Strand: Direct

Name: nifU [H]

Synonym: Aave_2444

Alternate gene names: 120611115

Gene position: 2669214-2669612 (Clockwise)

Preceding gene: 120611114

Following gene: 120611116

Centisome position: 49.87

GC content: 63.16

Gene sequence:

>399_bases
ATGGCTTACTCCGACAAGGTCATCGACCATTACGAAAACCCCCGCAACGTGGGTTCGTTCGACAAGAGCGACGATTCCGT
GGGCACCGGCATGGTGGGCGCTCCCGCCTGCGGCGACGTGATGAAGCTGCAGATCAAGGTGAACCCGGAAACCGGTGTGA
TCGAGGACGCACGGTTCAAGACGTATGGCTGCGGCTCGGCCATCGCTTCCTCGTCCCTGGTCACCGAATGGGTCAAGGGC
AAGACGCTGGACGAGGCGGCGGCGCTCAAGAACGCCGAGATCGCCCAGGAACTGGCTCTGCCGCCGGTCAAGATCCATTG
CTCCATCCTGGCCGAGGATGCGATCAAGGCCGCCGTGCAGGACTACAAGGCCAAGCACTCGGCCCTGGCGGGAGCCTGA

Upstream 100 bases:

>100_bases
CCTGTGGGAAATGTACAAGGATGGCGTGGACATCAGCTCCATCCAATGGGCTGCCCACTGATCCCGGCAGCCACGAAGAA
GTGAAAGGCAGGTAGAAATC

Downstream 100 bases:

>100_bases
CCGGCCATGGCGATCACTCTCACGGAAGCCGCAGCGCGGCACGTCAGCCGGTACCTGTCCCGCAGAGGCAAGGGCCTGGG
CGTGCGTCTGGGGGTGAAGA

Product: FeS cluster assembly scaffold IscU

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 132; Mature: 131

Protein sequence:

>132_residues
MAYSDKVIDHYENPRNVGSFDKSDDSVGTGMVGAPACGDVMKLQIKVNPETGVIEDARFKTYGCGSAIASSSLVTEWVKG
KTLDEAAALKNAEIAQELALPPVKIHCSILAEDAIKAAVQDYKAKHSALAGA

Sequences:

>Translated_132_residues
MAYSDKVIDHYENPRNVGSFDKSDDSVGTGMVGAPACGDVMKLQIKVNPETGVIEDARFKTYGCGSAIASSSLVTEWVKG
KTLDEAAALKNAEIAQELALPPVKIHCSILAEDAIKAAVQDYKAKHSALAGA
>Mature_131_residues
AYSDKVIDHYENPRNVGSFDKSDDSVGTGMVGAPACGDVMKLQIKVNPETGVIEDARFKTYGCGSAIASSSLVTEWVKGK
TLDEAAALKNAEIAQELALPPVKIHCSILAEDAIKAAVQDYKAKHSALAGA

Specific function: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins (Potential) [H]

COG id: COG0822

COG function: function code C; NifU homolog involved in Fe-S cluster formation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nifU family [H]

Homologues:

Organism=Homo sapiens, GI56699456, Length=129, Percent_Identity=72.0930232558139, Blast_Score=196, Evalue=4e-51,
Organism=Homo sapiens, GI24307953, Length=129, Percent_Identity=71.3178294573643, Blast_Score=193, Evalue=4e-50,
Organism=Escherichia coli, GI1788878, Length=128, Percent_Identity=83.59375, Blast_Score=224, Evalue=1e-60,
Organism=Caenorhabditis elegans, GI17543474, Length=125, Percent_Identity=70.4, Blast_Score=191, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6325122, Length=125, Percent_Identity=72, Blast_Score=196, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6324800, Length=125, Percent_Identity=70.4, Blast_Score=192, Evalue=1e-50,
Organism=Drosophila melanogaster, GI21355597, Length=124, Percent_Identity=74.1935483870968, Blast_Score=196, Evalue=3e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011339
- InterPro:   IPR002871 [H]

Pfam domain/function: PF01592 NifU_N [H]

EC number: NA

Molecular weight: Translated: 13896; Mature: 13765

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYSDKVIDHYENPRNVGSFDKSDDSVGTGMVGAPACGDVMKLQIKVNPETGVIEDARFK
CCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCEECCCCC
TYGCGSAIASSSLVTEWVKGKTLDEAAALKNAEIAQELALPPVKIHCSILAEDAIKAAVQ
CCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHH
DYKAKHSALAGA
HHHHHHHHCCCC
>Mature Secondary Structure 
AYSDKVIDHYENPRNVGSFDKSDDSVGTGMVGAPACGDVMKLQIKVNPETGVIEDARFK
CCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCEECCCCC
TYGCGSAIASSSLVTEWVKGKTLDEAAALKNAEIAQELALPPVKIHCSILAEDAIKAAVQ
CCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHH
DYKAKHSALAGA
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]