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The map label for this gene is 120611091

Identifier: 120611091

GI number: 120611091

Start: 2642835

End: 2644220

Strand: Direct

Name: 120611091

Synonym: Aave_2420

Alternate gene names: NA

Gene position: 2642835-2644220 (Clockwise)

Preceding gene: 120611089

Following gene: 120611094

Centisome position: 49.37

GC content: 70.56

Gene sequence:

>1386_bases
ATGCGCCCTTCATTCCATCGCCTTGCCCTCCGAATCACCGGCCATGGCCGGGTGGCCGCGTCCCTGCTGGTGGTGGCCGC
GCTGGCCGGCTGCGGAGATACCGCCCGCCTGCCTGCCGAGGCAGGCATCGGCCCCCGGCCCGCGCTGCCGGAACCGCACA
GGTCCCTGATTCCCACCGTGCACATCGCGCCCGCCAAGGGGTGGCCGGACGGGGGCGCGCCGCAGCCCATGGCCGGCCTG
TCCGTGACGCCTTTCGCCCGCGGGCTCGAACATCCCCGCTGGGTGGTGGTGCTGCCCAACGGCGACGTGCTCGTGGCCGA
GAGCGACAAGCCGGCACCCGAAGGTCCGCCCCCGGACGACGGGTGGGTCAAGAAAGTGCGCAACTGGGTCATGGGCAAGG
TCATGGCCCGTGCCGGCTCCGGCAACCCGTCAGCCAACCGCATCACGCTCCTGCGCGATGCCGACGGGGACGGCGTGGCG
GAAACGCGCAGCGCGTTCCTGCAGGGGCTGCATTCTCCTTTCGGCATGGCACTGGTCGGCAGCGAGTTCTACGTCGCCAA
CACCGATGCCGTCGTGCGGTTTCCTTATGCCCCGGGACAGACCGCCATCGCGGCCGCGCCGGCCAAGGTCGTGGACCTGC
CCTCGCGGCCGCTCAACCATCACTGGACCAAGAACCTCATCGCCAGCCCCGATGGTGCGAAGCTGTATGTCACGGTCGGC
TCCAACAGCAACGTGGCCGAGAACGGCATGGAGGCGGAAGCCGGCCGCGCGGCCATCTGGGAAGTCGATCGCGCCACGGG
CGCGCACCGCGTCTTCGCGAGCGGCTTGCGCAACCCCAATGGCATGGGCTGGGAGCCGGGCTCCGGCAGGCTGTGGACCG
TGGTGAATGAGCGCGACGAGATCGGCAGCGACCTCGTGCCCGACTACCTCACCTCGGTGAAGGAGGGCGGCTTCTACGGC
TGGCCCTACAGCTATTGGGGCGGGAACGTGGATGTGCGTGTCCAGCCTCCACGGCCGGATCTGGTCGAGAAGGCCATCGT
GCCGGATTACGCCCTGGGCAACCACGTGGCGCCGCTGGGCATGGCTTTCGCGGGGGGCGGCAGCCCGGCCGCTCAACCCG
TGGCTCCGCAGCTCGCGCAGGGTGTGTTTGTCGGCCTGCACGGCTCATGGAACCGCAAGCCGCGCAGTGGCTACAAGGTG
GTGTTCGTGCCGTTCAGGAACGGCAAACCCGACGGCATGCCCCTGGATGTGTTGACCGGATTCGTGAGCGGCGATGGCGA
CGCCTGGGGCCGGCCCGTGGGCGTGGCGCTGGACGGGCGGGGCGGCCTGCTCGTGGCCGACGACGTCGGCAACACCCTGT
GGCGCGTGGCGGCGGCGCGGCCGTGA

Upstream 100 bases:

>100_bases
AGGCCATCGTTCGGCGAAGATGGCTGACATGGTTTCAGCGCGGCGGTGGCGAGACTGGCCGGCATCGCCCGCCACCTGCC
GGCCTGACCGGCCTCCCGCC

Downstream 100 bases:

>100_bases
CCGTCGCGGACACGGGGCCGCCCCATCCGTCCTGCATCATCTGCCAGACCGGCAGCTCCACCGCTTCATGACCGGTTCCG
AGAAGTTAGGGTCGTATTCC

Product: L-sorbosone dehydrogenase

Products: NA

Alternate protein names: SNDH [H]

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MRPSFHRLALRITGHGRVAASLLVVAALAGCGDTARLPAEAGIGPRPALPEPHRSLIPTVHIAPAKGWPDGGAPQPMAGL
SVTPFARGLEHPRWVVVLPNGDVLVAESDKPAPEGPPPDDGWVKKVRNWVMGKVMARAGSGNPSANRITLLRDADGDGVA
ETRSAFLQGLHSPFGMALVGSEFYVANTDAVVRFPYAPGQTAIAAAPAKVVDLPSRPLNHHWTKNLIASPDGAKLYVTVG
SNSNVAENGMEAEAGRAAIWEVDRATGAHRVFASGLRNPNGMGWEPGSGRLWTVVNERDEIGSDLVPDYLTSVKEGGFYG
WPYSYWGGNVDVRVQPPRPDLVEKAIVPDYALGNHVAPLGMAFAGGGSPAAQPVAPQLAQGVFVGLHGSWNRKPRSGYKV
VFVPFRNGKPDGMPLDVLTGFVSGDGDAWGRPVGVALDGRGGLLVADDVGNTLWRVAAARP

Sequences:

>Translated_461_residues
MRPSFHRLALRITGHGRVAASLLVVAALAGCGDTARLPAEAGIGPRPALPEPHRSLIPTVHIAPAKGWPDGGAPQPMAGL
SVTPFARGLEHPRWVVVLPNGDVLVAESDKPAPEGPPPDDGWVKKVRNWVMGKVMARAGSGNPSANRITLLRDADGDGVA
ETRSAFLQGLHSPFGMALVGSEFYVANTDAVVRFPYAPGQTAIAAAPAKVVDLPSRPLNHHWTKNLIASPDGAKLYVTVG
SNSNVAENGMEAEAGRAAIWEVDRATGAHRVFASGLRNPNGMGWEPGSGRLWTVVNERDEIGSDLVPDYLTSVKEGGFYG
WPYSYWGGNVDVRVQPPRPDLVEKAIVPDYALGNHVAPLGMAFAGGGSPAAQPVAPQLAQGVFVGLHGSWNRKPRSGYKV
VFVPFRNGKPDGMPLDVLTGFVSGDGDAWGRPVGVALDGRGGLLVADDVGNTLWRVAAARP
>Mature_461_residues
MRPSFHRLALRITGHGRVAASLLVVAALAGCGDTARLPAEAGIGPRPALPEPHRSLIPTVHIAPAKGWPDGGAPQPMAGL
SVTPFARGLEHPRWVVVLPNGDVLVAESDKPAPEGPPPDDGWVKKVRNWVMGKVMARAGSGNPSANRITLLRDADGDGVA
ETRSAFLQGLHSPFGMALVGSEFYVANTDAVVRFPYAPGQTAIAAAPAKVVDLPSRPLNHHWTKNLIASPDGAKLYVTVG
SNSNVAENGMEAEAGRAAIWEVDRATGAHRVFASGLRNPNGMGWEPGSGRLWTVVNERDEIGSDLVPDYLTSVKEGGFYG
WPYSYWGGNVDVRVQPPRPDLVEKAIVPDYALGNHVAPLGMAFAGGGSPAAQPVAPQLAQGVFVGLHGSWNRKPRSGYKV
VFVPFRNGKPDGMPLDVLTGFVSGDGDAWGRPVGVALDGRGGLLVADDVGNTLWRVAAARP

Specific function: Converts L-sorbosone into 2-keto-L-gulonic acid (2KGA) [H]

COG id: COG2133

COG function: function code G; Glucose/sorbosone dehydrogenases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.burgdorferi BB024 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR012938
- InterPro:   IPR011041 [H]

Pfam domain/function: PF07995 GSDH [H]

EC number: NA

Molecular weight: Translated: 48501; Mature: 48501

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPSFHRLALRITGHGRVAASLLVVAALAGCGDTARLPAEAGIGPRPALPEPHRSLIPTV
CCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCCCHHHCCEE
HIAPAKGWPDGGAPQPMAGLSVTPFARGLEHPRWVVVLPNGDVLVAESDKPAPEGPPPDD
EEECCCCCCCCCCCCCCCCCEECHHHHCCCCCEEEEEECCCCEEEECCCCCCCCCCCCCH
GWVKKVRNWVMGKVMARAGSGNPSANRITLLRDADGDGVAETRSAFLQGLHSPFGMALVG
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEC
SEFYVANTDAVVRFPYAPGQTAIAAAPAKVVDLPSRPLNHHWTKNLIASPDGAKLYVTVG
CEEEEECCCEEEEECCCCCCCEEEECCCCEEECCCCCCCCCHHHHHCCCCCCCEEEEEEC
SNSNVAENGMEAEAGRAAIWEVDRATGAHRVFASGLRNPNGMGWEPGSGRLWTVVNERDE
CCCCHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEECCHHH
IGSDLVPDYLTSVKEGGFYGWPYSYWGGNVDVRVQPPRPDLVEKAIVPDYALGNHVAPLG
CCCCHHHHHHHHHHCCCEECCCHHHCCCCEEEEEECCCCHHHHHHCCCCCCCCCCCCCCC
MAFAGGGSPAAQPVAPQLAQGVFVGLHGSWNRKPRSGYKVVFVPFRNGKPDGMPLDVLTG
EEEECCCCCCCCCCCHHHHCCEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHEE
FVSGDGDAWGRPVGVALDGRGGLLVADDVGNTLWRVAAARP
EECCCCCCCCCEEEEEECCCCCEEEECCCCCCHHHHCCCCC
>Mature Secondary Structure
MRPSFHRLALRITGHGRVAASLLVVAALAGCGDTARLPAEAGIGPRPALPEPHRSLIPTV
CCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCCCHHHCCEE
HIAPAKGWPDGGAPQPMAGLSVTPFARGLEHPRWVVVLPNGDVLVAESDKPAPEGPPPDD
EEECCCCCCCCCCCCCCCCCEECHHHHCCCCCEEEEEECCCCEEEECCCCCCCCCCCCCH
GWVKKVRNWVMGKVMARAGSGNPSANRITLLRDADGDGVAETRSAFLQGLHSPFGMALVG
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEC
SEFYVANTDAVVRFPYAPGQTAIAAAPAKVVDLPSRPLNHHWTKNLIASPDGAKLYVTVG
CEEEEECCCEEEEECCCCCCCEEEECCCCEEECCCCCCCCCHHHHHCCCCCCCEEEEEEC
SNSNVAENGMEAEAGRAAIWEVDRATGAHRVFASGLRNPNGMGWEPGSGRLWTVVNERDE
CCCCHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEECCHHH
IGSDLVPDYLTSVKEGGFYGWPYSYWGGNVDVRVQPPRPDLVEKAIVPDYALGNHVAPLG
CCCCHHHHHHHHHHCCCEECCCHHHCCCCEEEEEECCCCHHHHHHCCCCCCCCCCCCCCC
MAFAGGGSPAAQPVAPQLAQGVFVGLHGSWNRKPRSGYKVVFVPFRNGKPDGMPLDVLTG
EEEECCCCCCCCCCCHHHHCCEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHEE
FVSGDGDAWGRPVGVALDGRGGLLVADDVGNTLWRVAAARP
EECCCCCCCCCEEEEEECCCCCEEEECCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7574579 [H]