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The map label for this gene is aes [C]

Identifier: 120610966

GI number: 120610966

Start: 2522197

End: 2523165

Strand: Reverse

Name: aes [C]

Synonym: Aave_2292

Alternate gene names: 120610966

Gene position: 2523165-2522197 (Counterclockwise)

Preceding gene: 120610969

Following gene: 120610965

Centisome position: 47.14

GC content: 73.07

Gene sequence:

>969_bases
GTGCCTCCTATATTTCCGCCCCCTACGTCCTTCTGGAAACGCGCCGCCCGCCTTGCCGGCCTCCTGGCCCTGGCCGCCGG
GCTGAGCGCCTGCTCCGGTGTCGGTACCCTGAATGCACTCGCGCAGCGCAGCGCCGCCGCGGTGGACACCGGCGTGGCCT
ACGGCACCCTGCCCCGCCAGCGGCTGGATGTGTACCGTCCCTCGGTGGCCGCCCCGGCCGGCGGCTGGCCGGTGGTGGTG
TTCTTCTATGGCGGCACCTGGAACAGCGGGGAACGGGGCGATTACCTGTTCCTGGGCCAGGCGCTGGCGTCGCGCGGGGT
GCTGGCGCTGGTGGCGGACTACCGGCTGTATCCGGAGGTGCGGTATCCGGATTTCGTCGCCGACAGCGCGCTGGCGGTGG
CCTATGGGCTCGAGCATGCGGCGCGGCTCGGCGGCAATCCGCGCCGGGTGTTCGCGATGGGGCACAGCGCAGGCGCATAC
AACGCGGCGATGGTGGCGCTGGATCCGCGCTGGCTGGCGGCCACGGGGCATGCGCCGCGCGAGCTGGCGGGCTGGATCGG
GCTGGCGGGGCCGTACGACTTCTTTCCCACGGACAACCCGGAGGCGCAGCCGGTGTTCTTCCACCCGAACTACCCCGCAC
GCTCCCAACCCATCGAGTTCGCGCACCCGGCCGTGCCCGCGCAGGTGCCCCGGGCCTTCCTGGGCGCGCCGGAGAAGGAC
CGGCTGGTGAGCCCGCAGCGCAGCACGCTGCAGCTGGCGCAGGCACTGCAGGCGGCCGGCGTGCCCGTGGTGCTGCAGCT
CTATCCGCGCGCCAGCCATACGACGCTGGTGGGCGCGTTCGCATGGCCGCTGCGCTGGGTGGCGCCGGTACTGGACGACG
TGGCCGGGTTCATCGCCTCGGCCCCGCCCGCGGCGCCGGCACCGAATATGCGGGAAGCCCCGCTTGAAGGCGCTTCGGCG
GGCAGCTAA

Upstream 100 bases:

>100_bases
TAATATTTTATCAAGGGAATGAAACAAAATTTTTCACTCAAAAATCCAAAATTCGGCAGAAAACGTACAAAACTATAAAC
CCCTTGCATGGGAAACTCAC

Downstream 100 bases:

>100_bases
GTTGGCGGCTTTCCCCGTTCCGCGCACCCTGCGCAAGGAGAGACGCATGCCTGCTTCCACCCCCGCCGGTACCGGCACCG
TGACCCTGCACCGCGTGCTG

Product: esterase/lipase/thioesterase family protein

Products: alcohol; a carboxylate [C]

Alternate protein names: Lipase; Alpha/Beta Hydrolase Fold-3 Domain Protein; Alpha/Beta Hydrolase Domain-Containing Protein; Carboxylesterase Family Protein; Esterase; Carboxylesterase; Hydrolase; Esterase/Lipase; Para-Nitrobenzyl Esterase; Esterase/Lipase/Thioesterase; Lipase/Esterase; Alpha/Beta Hydrolase; Alpha/Beta Hydrolase Family Protein; Conserved Domain Protein; Esterase/Lipase/Thiestherase Protein; Esterase/Lipase-Like Protein; Alpha/Beta Hydrolase Fold; Alpha/Beta Hydrolase Protein

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MPPIFPPPTSFWKRAARLAGLLALAAGLSACSGVGTLNALAQRSAAAVDTGVAYGTLPRQRLDVYRPSVAAPAGGWPVVV
FFYGGTWNSGERGDYLFLGQALASRGVLALVADYRLYPEVRYPDFVADSALAVAYGLEHAARLGGNPRRVFAMGHSAGAY
NAAMVALDPRWLAATGHAPRELAGWIGLAGPYDFFPTDNPEAQPVFFHPNYPARSQPIEFAHPAVPAQVPRAFLGAPEKD
RLVSPQRSTLQLAQALQAAGVPVVLQLYPRASHTTLVGAFAWPLRWVAPVLDDVAGFIASAPPAAPAPNMREAPLEGASA
GS

Sequences:

>Translated_322_residues
MPPIFPPPTSFWKRAARLAGLLALAAGLSACSGVGTLNALAQRSAAAVDTGVAYGTLPRQRLDVYRPSVAAPAGGWPVVV
FFYGGTWNSGERGDYLFLGQALASRGVLALVADYRLYPEVRYPDFVADSALAVAYGLEHAARLGGNPRRVFAMGHSAGAY
NAAMVALDPRWLAATGHAPRELAGWIGLAGPYDFFPTDNPEAQPVFFHPNYPARSQPIEFAHPAVPAQVPRAFLGAPEKD
RLVSPQRSTLQLAQALQAAGVPVVLQLYPRASHTTLVGAFAWPLRWVAPVLDDVAGFIASAPPAAPAPNMREAPLEGASA
GS
>Mature_321_residues
PPIFPPPTSFWKRAARLAGLLALAAGLSACSGVGTLNALAQRSAAAVDTGVAYGTLPRQRLDVYRPSVAAPAGGWPVVVF
FYGGTWNSGERGDYLFLGQALASRGVLALVADYRLYPEVRYPDFVADSALAVAYGLEHAARLGGNPRRVFAMGHSAGAYN
AAMVALDPRWLAATGHAPRELAGWIGLAGPYDFFPTDNPEAQPVFFHPNYPARSQPIEFAHPAVPAQVPRAFLGAPEKDR
LVSPQRSTLQLAQALQAAGVPVVLQLYPRASHTTLVGAFAWPLRWVAPVLDDVAGFIASAPPAAPAPNMREAPLEGASAG
S

Specific function: Has An Esterase Activity. Triacetyl Glycerol (Triacetin) Is A Substrate Of The Enzyme. [C]

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.1.1.- [C]

Molecular weight: Translated: 33940; Mature: 33809

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPIFPPPTSFWKRAARLAGLLALAAGLSACSGVGTLNALAQRSAAAVDTGVAYGTLPRQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHCCCCHH
RLDVYRPSVAAPAGGWPVVVFFYGGTWNSGERGDYLFLGQALASRGVLALVADYRLYPEV
HHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEEEEHHHHHCCEEEEEECHHHCCCC
RYPDFVADSALAVAYGLEHAARLGGNPRRVFAMGHSAGAYNAAMVALDPRWLAATGHAPR
CCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEECCCEEEECCCCHH
ELAGWIGLAGPYDFFPTDNPEAQPVFFHPNYPARSQPIEFAHPAVPAQVPRAFLGAPEKD
HHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHH
RLVSPQRSTLQLAQALQAAGVPVVLQLYPRASHTTLVGAFAWPLRWVAPVLDDVAGFIAS
CCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHC
APPAAPAPNMREAPLEGASAGS
CCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PPIFPPPTSFWKRAARLAGLLALAAGLSACSGVGTLNALAQRSAAAVDTGVAYGTLPRQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHCCCCHH
RLDVYRPSVAAPAGGWPVVVFFYGGTWNSGERGDYLFLGQALASRGVLALVADYRLYPEV
HHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEEEEHHHHHCCEEEEEECHHHCCCC
RYPDFVADSALAVAYGLEHAARLGGNPRRVFAMGHSAGAYNAAMVALDPRWLAATGHAPR
CCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEECCCEEEECCCCHH
ELAGWIGLAGPYDFFPTDNPEAQPVFFHPNYPARSQPIEFAHPAVPAQVPRAFLGAPEKD
HHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHH
RLVSPQRSTLQLAQALQAAGVPVVLQLYPRASHTTLVGAFAWPLRWVAPVLDDVAGFIAS
CCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHC
APPAAPAPNMREAPLEGASAGS
CCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Carboxylic ester; H2O [C]

Specific reaction: Carboxylic ester + H2O = an alcohol + carboxylate [C]

General reaction: Hydrolase; Acting on ester bonds; Carboxylic ester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA