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The map label for this gene is yycG [H]

Identifier: 120610941

GI number: 120610941

Start: 2498007

End: 2499218

Strand: Reverse

Name: yycG [H]

Synonym: Aave_2267

Alternate gene names: 120610941

Gene position: 2499218-2498007 (Counterclockwise)

Preceding gene: 120610942

Following gene: 120610937

Centisome position: 46.69

GC content: 72.61

Gene sequence:

>1212_bases
ATGCATTCCACCGCCCGTGCCCTGGCGGCCCGCCACGCGCCGCAGCGCCTGGAAGCCGTGGAGGCCACGGGCCTGCTCGA
CTCCCCCGCGGAGCCGGGCTTCGACAGCCTGACGGCGACCGCGGCCCGCCTGCTGGGCGCCGCGGCATGCTTCATTTCCG
TCGTCGATGCGCGGCGCGACTTCTACAAGAGCCAGTCCGGCTTTCCCGAGGCGCTGGCCCGCGCCCGCGAAATGGAGGGC
CTGACGTTCTGCCACTTCACGCTGGACCGGGACGATGCGCTGGTCATCCGCGACACGCACACCGAGCCGCAATGGCGCGC
CGTGCCCACCGTGCAGAGCCTGGGCGTGCGCGCCTACGTGGGCGTGCCCCTGAAGGCGCACGGGCAGAACATCGGCAGTT
TCTGCGTGATCGACACGCGTCCGCGCGCCTGGACGGACGACGAGCTGGAGACCATCCGCCAGCTGGCCGTCTCCGCGGCG
CGCGAACTGGACCTGCGCACCGCCCTGGCCGCCGCGCAGGAGGCCGCAGCCACGGCCCGCGCCCAGGCCCTGGCGCGCGA
GCGGGTGCTGGCGGCGGTCGCGCACGACCTGCGCACGCCGCTGCAGGTGCTGCAGCTCAGTGCCACGCACATCCAGCGCA
GCGCGGAGGCGCCGCCGGACGCGGTGGTGCAGCGCATGCTGTCGGCCGTGGGCATGATGGCCTCGCTGGTGGAAGGCCTG
CTGCGGCCGTCCGATTCGGCATCGACCGTGCAGGCCCTGCCGCTGGCGACGCTGGCCACCGACGCGGTCGAGATGATGGC
GCCCATCGCCGAGAAATGCGGCATCGCGCTCGTGCTGGGGCCGGTGCCCGACACGCTGGTGCGGGTGGACTACGGCCAGA
TGGTGCGGGTGCTGGGCAACCTGATCTGCAATTCGCTCAAGTATTCGCCCGAGGGCAGCACCGTGCGCATGGCCGGCACC
TGCAGTTCGCCGCACGCCGCGCGATCGGTCGAACTCACGGTGGCGGACAACGGCATGGGCATGGGCCCGGAAGAAGTCGC
CCGCGCGTTCGAGCCGGGCTGGCAGGGCGAGACGGCCCGTGCCCGCAAGGATGGCGTCGGCCTGGGCCTGGGCATCGTCA
AATCCCTGGTGGAAGCCAACCGCGGCCAGGTGCGCATGGAAAGCCGCCCCGGCCAGGGCACCTCCGTCACCATCACGCTG
CCGCGCGCCTGA

Upstream 100 bases:

>100_bases
TGGCCCCGGGCACTCTACGGTATTGCTGTCGCGTTATTCTCTGCCCATGCATGCCACTGCGCCCCCTCCCCCCGAGCCGG
CCGACGCCTCCCTGGAGGGT

Downstream 100 bases:

>100_bases
GCGGGGCGCCCGCGTTCAGCGCGCCGCCACCATGCGCAGGCCCAGCGCGATGAACACCGTGCCCGCGATGCGGTCCAGCC
ACAGGCCGGCGCGCGGCCGC

Product: GAF sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MHSTARALAARHAPQRLEAVEATGLLDSPAEPGFDSLTATAARLLGAAACFISVVDARRDFYKSQSGFPEALARAREMEG
LTFCHFTLDRDDALVIRDTHTEPQWRAVPTVQSLGVRAYVGVPLKAHGQNIGSFCVIDTRPRAWTDDELETIRQLAVSAA
RELDLRTALAAAQEAAATARAQALARERVLAAVAHDLRTPLQVLQLSATHIQRSAEAPPDAVVQRMLSAVGMMASLVEGL
LRPSDSASTVQALPLATLATDAVEMMAPIAEKCGIALVLGPVPDTLVRVDYGQMVRVLGNLICNSLKYSPEGSTVRMAGT
CSSPHAARSVELTVADNGMGMGPEEVARAFEPGWQGETARARKDGVGLGLGIVKSLVEANRGQVRMESRPGQGTSVTITL
PRA

Sequences:

>Translated_403_residues
MHSTARALAARHAPQRLEAVEATGLLDSPAEPGFDSLTATAARLLGAAACFISVVDARRDFYKSQSGFPEALARAREMEG
LTFCHFTLDRDDALVIRDTHTEPQWRAVPTVQSLGVRAYVGVPLKAHGQNIGSFCVIDTRPRAWTDDELETIRQLAVSAA
RELDLRTALAAAQEAAATARAQALARERVLAAVAHDLRTPLQVLQLSATHIQRSAEAPPDAVVQRMLSAVGMMASLVEGL
LRPSDSASTVQALPLATLATDAVEMMAPIAEKCGIALVLGPVPDTLVRVDYGQMVRVLGNLICNSLKYSPEGSTVRMAGT
CSSPHAARSVELTVADNGMGMGPEEVARAFEPGWQGETARARKDGVGLGLGIVKSLVEANRGQVRMESRPGQGTSVTITL
PRA
>Mature_403_residues
MHSTARALAARHAPQRLEAVEATGLLDSPAEPGFDSLTATAARLLGAAACFISVVDARRDFYKSQSGFPEALARAREMEG
LTFCHFTLDRDDALVIRDTHTEPQWRAVPTVQSLGVRAYVGVPLKAHGQNIGSFCVIDTRPRAWTDDELETIRQLAVSAA
RELDLRTALAAAQEAAATARAQALARERVLAAVAHDLRTPLQVLQLSATHIQRSAEAPPDAVVQRMLSAVGMMASLVEGL
LRPSDSASTVQALPLATLATDAVEMMAPIAEKCGIALVLGPVPDTLVRVDYGQMVRVLGNLICNSLKYSPEGSTVRMAGT
CSSPHAARSVELTVADNGMGMGPEEVARAFEPGWQGETARARKDGVGLGLGIVKSLVEANRGQVRMESRPGQGTSVTITL
PRA

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG5002

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=267, Percent_Identity=29.9625468164794, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788713, Length=252, Percent_Identity=29.7619047619048, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788393, Length=240, Percent_Identity=29.5833333333333, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1786912, Length=302, Percent_Identity=28.476821192053, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1790346, Length=229, Percent_Identity=27.9475982532751, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI145693157, Length=244, Percent_Identity=26.2295081967213, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786783, Length=221, Percent_Identity=30.7692307692308, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789149, Length=265, Percent_Identity=25.6603773584906, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790436, Length=218, Percent_Identity=27.0642201834862, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1789808, Length=346, Percent_Identity=23.6994219653179, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 42796; Mature: 42796

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSTARALAARHAPQRLEAVEATGLLDSPAEPGFDSLTATAARLLGAAACFISVVDARRD
CCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FYKSQSGFPEALARAREMEGLTFCHFTLDRDDALVIRDTHTEPQWRAVPTVQSLGVRAYV
HHHCCCCCHHHHHHHHHCCCCEEEEEEECCCCEEEEEECCCCCCCEECCCHHHCCCEEEE
GVPLKAHGQNIGSFCVIDTRPRAWTDDELETIRQLAVSAARELDLRTALAAAQEAAATAR
CCCHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQALARERVLAAVAHDLRTPLQVLQLSATHIQRSAEAPPDAVVQRMLSAVGMMASLVEGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
LRPSDSASTVQALPLATLATDAVEMMAPIAEKCGIALVLGPVPDTLVRVDYGQMVRVLGN
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCEEECCHHHHHHHHHH
LICNSLKYSPEGSTVRMAGTCSSPHAARSVELTVADNGMGMGPEEVARAFEPGWQGETAR
HHHHHCCCCCCCCEEEEEECCCCCCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCCCCH
ARKDGVGLGLGIVKSLVEANRGQVRMESRPGQGTSVTITLPRA
HHHCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCEEEEEECCC
>Mature Secondary Structure
MHSTARALAARHAPQRLEAVEATGLLDSPAEPGFDSLTATAARLLGAAACFISVVDARRD
CCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FYKSQSGFPEALARAREMEGLTFCHFTLDRDDALVIRDTHTEPQWRAVPTVQSLGVRAYV
HHHCCCCCHHHHHHHHHCCCCEEEEEEECCCCEEEEEECCCCCCCEECCCHHHCCCEEEE
GVPLKAHGQNIGSFCVIDTRPRAWTDDELETIRQLAVSAARELDLRTALAAAQEAAATAR
CCCHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQALARERVLAAVAHDLRTPLQVLQLSATHIQRSAEAPPDAVVQRMLSAVGMMASLVEGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
LRPSDSASTVQALPLATLATDAVEMMAPIAEKCGIALVLGPVPDTLVRVDYGQMVRVLGN
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCEEECCHHHHHHHHHH
LICNSLKYSPEGSTVRMAGTCSSPHAARSVELTVADNGMGMGPEEVARAFEPGWQGETAR
HHHHHCCCCCCCCEEEEEECCCCCCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCCCCH
ARKDGVGLGLGIVKSLVEANRGQVRMESRPGQGTSVTITLPRA
HHHCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]