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The map label for this gene is ribB [H]

Identifier: 120610906

GI number: 120610906

Start: 2451815

End: 2452936

Strand: Reverse

Name: ribB [H]

Synonym: Aave_2232

Alternate gene names: 120610906

Gene position: 2452936-2451815 (Counterclockwise)

Preceding gene: 120610907

Following gene: 120610905

Centisome position: 45.83

GC content: 70.94

Gene sequence:

>1122_bases
ATGAACACCCCCCTTCCCCCCGCGTCCATCTCGCCCGTCGAAGACATCGTGGCGGAGATGCGCGCCGGGCGCATCGTCAT
CCTCGTGGACGAGGAAGACCGCGAGAACGAAGGCGACCTGGTCCTGGCCGCCGACCACGTCACCCCCGAAGCGATCAACT
TCATGGCGCGTTTCGGCCGCGGCCTCATCTGCCTCACGCTCACCCGCGAGCGCTGCGAACTGCTGCGGCTGCCGCCCATG
GTGGCGCGCAACGGCACCAAGATGGGCACGGCCTTCACCGCCTCCATCGAGGCCGCCGAGGGCGTGACCACCGGCATCTC
CGCCGCCGACCGCGCCCGCACCGTGCAGGCCGCCGTGGCACCGGACGCCAAGGCCTCCGACCTGGTGCAGCCCGGCCACA
TCTTCCCGCTGCAGGCGGTCGATGGCGGCGTGCTCATGCGCGCCGGCCATACCGAAGCCGGCTGCGACCTGGCCGCCATG
GCAGGCTGCAGCCCGTCCGCCGTGATCTGCGAGGTCATGAAGGACGACGGCACCATGGCCCGCCTGCCCGACCTGCAGCA
GTTCGCCGCCGAGCACGGCCTGAAGATCGGCACCATCGCCGACCTCATCGAATACCGCAGCCGCAACGAAACGCTGGTGC
AGAAGGTAGGCACCCGCCCGCTGCAGACGGCCGCCGGCGAATTCATCGCGCATGCCTTCCGCGACGGCCCCAGCCAGTCG
GTCCACATCGCCCTGGTGCGCGGCACCTGGGGCGAGCACGACAGCGTCCCGGTGCGCGTGCACGAGCCGCTGTCCGTGCT
CGACGCGCTGGAAGTGGGCCGCGACATGCACTCCTGGGACCTGGACGCCAGCCTGCGCCACATCGCCCGGCACGGCTGCG
GCGTGGCGGTGCTGCTGAACTGCGGCGAGAGCGCCGAGCAATTGCTGGCCCAGTTCGACGGCACCGCGCGCGCGTCGCAC
GCGCCGGAGCGCGGCCGCATGGACCTGCGCACCTACGGCGTCGGCGCGCAGATCCTGCGCGAATGCGGCGTCACGCGCAT
GCAGCTCATGGGCCAGCAGCGGCGCCTGCCCAGCATGACCGGCTACGGCCTCGAGATCACCGGATACATCCCCAAGGAAT
AA

Upstream 100 bases:

>100_bases
CACGCCGGGACTCCTCCGCGGGGGGCGGCCGCCTGCACTAAAATCCCCCTTTTCCCGGCGGCGCGGTCCGGCCGCCGCGG
ACCACCGAAAGCCCGCCCCC

Downstream 100 bases:

>100_bases
GCAACACATGTTTGGCGCAGACAAAGGAACCGCGGACAGGCTCGACGGCAGGAAGCTGCACATCGGCATCGTGCAGGCCC
GCTTCAACGAAGGCATCACC

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MNTPLPPASISPVEDIVAEMRAGRIVILVDEEDRENEGDLVLAADHVTPEAINFMARFGRGLICLTLTRERCELLRLPPM
VARNGTKMGTAFTASIEAAEGVTTGISAADRARTVQAAVAPDAKASDLVQPGHIFPLQAVDGGVLMRAGHTEAGCDLAAM
AGCSPSAVICEVMKDDGTMARLPDLQQFAAEHGLKIGTIADLIEYRSRNETLVQKVGTRPLQTAAGEFIAHAFRDGPSQS
VHIALVRGTWGEHDSVPVRVHEPLSVLDALEVGRDMHSWDLDASLRHIARHGCGVAVLLNCGESAEQLLAQFDGTARASH
APERGRMDLRTYGVGAQILRECGVTRMQLMGQQRRLPSMTGYGLEITGYIPKE

Sequences:

>Translated_373_residues
MNTPLPPASISPVEDIVAEMRAGRIVILVDEEDRENEGDLVLAADHVTPEAINFMARFGRGLICLTLTRERCELLRLPPM
VARNGTKMGTAFTASIEAAEGVTTGISAADRARTVQAAVAPDAKASDLVQPGHIFPLQAVDGGVLMRAGHTEAGCDLAAM
AGCSPSAVICEVMKDDGTMARLPDLQQFAAEHGLKIGTIADLIEYRSRNETLVQKVGTRPLQTAAGEFIAHAFRDGPSQS
VHIALVRGTWGEHDSVPVRVHEPLSVLDALEVGRDMHSWDLDASLRHIARHGCGVAVLLNCGESAEQLLAQFDGTARASH
APERGRMDLRTYGVGAQILRECGVTRMQLMGQQRRLPSMTGYGLEITGYIPKE
>Mature_373_residues
MNTPLPPASISPVEDIVAEMRAGRIVILVDEEDRENEGDLVLAADHVTPEAINFMARFGRGLICLTLTRERCELLRLPPM
VARNGTKMGTAFTASIEAAEGVTTGISAADRARTVQAAVAPDAKASDLVQPGHIFPLQAVDGGVLMRAGHTEAGCDLAAM
AGCSPSAVICEVMKDDGTMARLPDLQQFAAEHGLKIGTIADLIEYRSRNETLVQKVGTRPLQTAAGEFIAHAFRDGPSQS
VHIALVRGTWGEHDSVPVRVHEPLSVLDALEVGRDMHSWDLDASLRHIARHGCGVAVLLNCGESAEQLLAQFDGTARASH
APERGRMDLRTYGVGAQILRECGVTRMQLMGQQRRLPSMTGYGLEITGYIPKE

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the GTP cyclohydrolase II family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=213, Percent_Identity=50.7042253521127, Blast_Score=210, Evalue=1e-55,
Organism=Saccharomyces cerevisiae, GI6320695, Length=209, Percent_Identity=40.6698564593301, Blast_Score=162, Evalue=8e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422
- InterPro:   IPR000926
- InterPro:   IPR016299 [H]

Pfam domain/function: PF00926 DHBP_synthase; PF00925 GTP_cyclohydro2 [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 40053; Mature: 40053

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTPLPPASISPVEDIVAEMRAGRIVILVDEEDRENEGDLVLAADHVTPEAINFMARFGR
CCCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHCC
GLICLTLTRERCELLRLPPMVARNGTKMGTAFTASIEAAEGVTTGISAADRARTVQAAVA
CEEEEEECHHHHHHHCCCCHHHCCCCCCCEEEEEECHHHCCCHHCCCHHHHHHHHHHHCC
PDAKASDLVQPGHIFPLQAVDGGVLMRAGHTEAGCDLAAMAGCSPSAVICEVMKDDGTMA
CCCCHHHCCCCCCEEEEEECCCCEEEECCCCCCCCCHHHHCCCCCHHHHHHHHHCCCCEE
RLPDLQQFAAEHGLKIGTIADLIEYRSRNETLVQKVGTRPLQTAAGEFIAHAFRDGPSQS
CCCCHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCC
VHIALVRGTWGEHDSVPVRVHEPLSVLDALEVGRDMHSWDLDASLRHIARHGCGVAVLLN
EEEEEEECCCCCCCCCCEEECCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEE
CGESAEQLLAQFDGTARASHAPERGRMDLRTYGVGAQILRECGVTRMQLMGQQRRLPSMT
CCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCHHHHHHHCCHHHHHHHHHHHCCCCCC
GYGLEITGYIPKE
CCCEEEEECCCCC
>Mature Secondary Structure
MNTPLPPASISPVEDIVAEMRAGRIVILVDEEDRENEGDLVLAADHVTPEAINFMARFGR
CCCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHCC
GLICLTLTRERCELLRLPPMVARNGTKMGTAFTASIEAAEGVTTGISAADRARTVQAAVA
CEEEEEECHHHHHHHCCCCHHHCCCCCCCEEEEEECHHHCCCHHCCCHHHHHHHHHHHCC
PDAKASDLVQPGHIFPLQAVDGGVLMRAGHTEAGCDLAAMAGCSPSAVICEVMKDDGTMA
CCCCHHHCCCCCCEEEEEECCCCEEEECCCCCCCCCHHHHCCCCCHHHHHHHHHCCCCEE
RLPDLQQFAAEHGLKIGTIADLIEYRSRNETLVQKVGTRPLQTAAGEFIAHAFRDGPSQS
CCCCHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCC
VHIALVRGTWGEHDSVPVRVHEPLSVLDALEVGRDMHSWDLDASLRHIARHGCGVAVLLN
EEEEEEECCCCCCCCCCEEECCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEE
CGESAEQLLAQFDGTARASHAPERGRMDLRTYGVGAQILRECGVTRMQLMGQQRRLPSMT
CCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCHHHHHHHCCHHHHHHHHHHHCCCCCC
GYGLEITGYIPKE
CCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]