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The map label for this gene is yhjE [H]

Identifier: 120610898

GI number: 120610898

Start: 2445306

End: 2446640

Strand: Direct

Name: yhjE [H]

Synonym: Aave_2224

Alternate gene names: 120610898

Gene position: 2445306-2446640 (Clockwise)

Preceding gene: 120610890

Following gene: 120610913

Centisome position: 45.68

GC content: 67.87

Gene sequence:

>1335_bases
ATGAGTGGGCTTGCTGCTTCCGCCTATCCCTCCGGGAGTTTCCATCACGAGGAATCCCTGTCCCATGCGGACACCCATGA
AGAAGCCACGCCCAGCGAGATCGCGGTCGGCGTGATCATCGGGCGTTCGTCCGAGTATTTCGACTTCTTCGTCTTCGGCA
TCGCCTGCGTGCTGGTGTTCCCGTCGTTCGTCTTTCCCTTCATGACGCGCCTGGACGGCACGCTGATGGCCTTCGCGATC
TTCGCGCTCGCCTTCGTCGCCCGTCCCGTGGGGACCGCCATCTCGATGGCGGTGCAGCGGCGCTGGGGGCGCGGCACCAA
GCTGACGCTCGCCCTGTTCCTGCTGGGCGCCTCCACGGCGGGCATGGCGTTCCTGCCGAGCTACAACAGCGTGGGCCACA
TCGCCATCATCGCCCTGGTCGTGCTGCGCCTGGGCCAGGGGGTGGCGCTGGGCGGTACCTGGGACGGCCTTCCCTCGCTG
CTGGCCATGTCCGCCCCGCCGGAGCGGCGTGGCTGGTACGCCATGATCGGGCAACTGGGCGCGCCGGTCGGCTTCGCGCT
CGCGGCCAGCCTGTTCGCCTATCTCTACTCCAACCTGTCGGTGCAGGAGTTCCTCGACTGGGGCTGGCGCTTTCCGTTCT
TCGTCGCCTTCGCGATCAACGTGGTGGCGCTTTTCGCCCGCCTGCGCCTGATCGTCGGCCAGTCCTATACCGAGATGATG
CAGCAGCGCGAGCTGGAGCCCGTGGGTGCGCTGGAACTCATGCGCAGCGAAGGCCGCAACGTGGTGCTGGGCGCCTTCGC
CGCGCTGGCGAGCTTCGCGCTCTTCCACGTGGTCACGGTGTTCCCGCTGTCGTGGATCTCGATGTATTCCGAGCAGTCGA
TCACCCACGTGCTGGGCGTGCAGATCGCCGGTGCCTTCTGCGCGGCCGTCGCCATCGCCATCTCCGGCCGCCTGGCCGAC
CGGGTGGGCCGCCGCAACACGCTGGGCGCCATGGCCTGCCTGATCGGGGTGTTCAGCCTGGTCACGCCGTGGCTGCTCAG
CAGCGGCACGGTAGGCAACAACATCTTCATCCTGGTGGGCTTCGTGCTGCTGGGCCTGTCGTACGGTCAGGCTTCCGGCA
CGGTGACGGCCAATTTCTCGCCGCGCTTCCGCTACACGGGGGCCGCGCTGTCGGCCGATCTCGCCTGGCTGGTCGGCGCC
GCGTTCGCGCCGCTGGTCGCCCTGGGCCTTTCGGCCAAGTTCGGGCTGATCGCTGTGAGCGTGTACCTGCTGTCCGGCGT
GGTCTGCACGCTGCTGGCGCTGCGGATCAACCGCCTGATCGAGCGCCGCGAATGA

Upstream 100 bases:

>100_bases
GGGTTTGTCCGACCCCTCCTAGGGGAAAAGGCGCCTTGTGGGGGCCACGGACGGGGTGTAGAACGGAAGCCGTGTTCAGC
ATGAATCGAGGAGCGTTCAT

Downstream 100 bases:

>100_bases
CCGGGGAATGACGAGGACGGCGCGCCGCAGGGCGCGCCGGCAGCGCGAGGAGAAGCGCGAAAGAACAAAGCCCGCGTCCT
GCGGGCTTTGTTCTTTGGGT

Product: major facilitator superfamily transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MSGLAASAYPSGSFHHEESLSHADTHEEATPSEIAVGVIIGRSSEYFDFFVFGIACVLVFPSFVFPFMTRLDGTLMAFAI
FALAFVARPVGTAISMAVQRRWGRGTKLTLALFLLGASTAGMAFLPSYNSVGHIAIIALVVLRLGQGVALGGTWDGLPSL
LAMSAPPERRGWYAMIGQLGAPVGFALAASLFAYLYSNLSVQEFLDWGWRFPFFVAFAINVVALFARLRLIVGQSYTEMM
QQRELEPVGALELMRSEGRNVVLGAFAALASFALFHVVTVFPLSWISMYSEQSITHVLGVQIAGAFCAAVAIAISGRLAD
RVGRRNTLGAMACLIGVFSLVTPWLLSSGTVGNNIFILVGFVLLGLSYGQASGTVTANFSPRFRYTGAALSADLAWLVGA
AFAPLVALGLSAKFGLIAVSVYLLSGVVCTLLALRINRLIERRE

Sequences:

>Translated_444_residues
MSGLAASAYPSGSFHHEESLSHADTHEEATPSEIAVGVIIGRSSEYFDFFVFGIACVLVFPSFVFPFMTRLDGTLMAFAI
FALAFVARPVGTAISMAVQRRWGRGTKLTLALFLLGASTAGMAFLPSYNSVGHIAIIALVVLRLGQGVALGGTWDGLPSL
LAMSAPPERRGWYAMIGQLGAPVGFALAASLFAYLYSNLSVQEFLDWGWRFPFFVAFAINVVALFARLRLIVGQSYTEMM
QQRELEPVGALELMRSEGRNVVLGAFAALASFALFHVVTVFPLSWISMYSEQSITHVLGVQIAGAFCAAVAIAISGRLAD
RVGRRNTLGAMACLIGVFSLVTPWLLSSGTVGNNIFILVGFVLLGLSYGQASGTVTANFSPRFRYTGAALSADLAWLVGA
AFAPLVALGLSAKFGLIAVSVYLLSGVVCTLLALRINRLIERRE
>Mature_443_residues
SGLAASAYPSGSFHHEESLSHADTHEEATPSEIAVGVIIGRSSEYFDFFVFGIACVLVFPSFVFPFMTRLDGTLMAFAIF
ALAFVARPVGTAISMAVQRRWGRGTKLTLALFLLGASTAGMAFLPSYNSVGHIAIIALVVLRLGQGVALGGTWDGLPSLL
AMSAPPERRGWYAMIGQLGAPVGFALAASLFAYLYSNLSVQEFLDWGWRFPFFVAFAINVVALFARLRLIVGQSYTEMMQ
QRELEPVGALELMRSEGRNVVLGAFAALASFALFHVVTVFPLSWISMYSEQSITHVLGVQIAGAFCAAVAIAISGRLADR
VGRRNTLGAMACLIGVFSLVTPWLLSSGTVGNNIFILVGFVLLGLSYGQASGTVTANFSPRFRYTGAALSADLAWLVGAA
FAPLVALGLSAKFGLIAVSVYLLSGVVCTLLALRINRLIERRE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789941, Length=438, Percent_Identity=32.648401826484, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI1788292, Length=423, Percent_Identity=29.0780141843972, Blast_Score=145, Evalue=7e-36,
Organism=Escherichia coli, GI1790550, Length=407, Percent_Identity=26.044226044226, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1788942, Length=429, Percent_Identity=26.8065268065268, Blast_Score=99, Evalue=8e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004736
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005828
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1; PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 47424; Mature: 47293

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGLAASAYPSGSFHHEESLSHADTHEEATPSEIAVGVIIGRSSEYFDFFVFGIACVLVF
CCCCCCCCCCCCCCCCHHHCCCCCCCCCCCHHHEEEEEEEECCCHHHHHHHHHHHHHHHH
PSFVFPFMTRLDGTLMAFAIFALAFVARPVGTAISMAVQRRWGRGTKLTLALFLLGASTA
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
GMAFLPSYNSVGHIAIIALVVLRLGQGVALGGTWDGLPSLLAMSAPPERRGWYAMIGQLG
CEEECCCCCCCHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHCCCCCCCCCHHHHHHHHC
APVGFALAASLFAYLYSNLSVQEFLDWGWRFPFFVAFAINVVALFARLRLIVGQSYTEMM
CCHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
QQRELEPVGALELMRSEGRNVVLGAFAALASFALFHVVTVFPLSWISMYSEQSITHVLGV
HHHCCCCHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QIAGAFCAAVAIAISGRLADRVGRRNTLGAMACLIGVFSLVTPWLLSSGTVGNNIFILVG
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
FVLLGLSYGQASGTVTANFSPRFRYTGAALSADLAWLVGAAFAPLVALGLSAKFGLIAVS
HHHHHCCCCCCCCEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VYLLSGVVCTLLALRINRLIERRE
HHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SGLAASAYPSGSFHHEESLSHADTHEEATPSEIAVGVIIGRSSEYFDFFVFGIACVLVF
CCCCCCCCCCCCCCCHHHCCCCCCCCCCCHHHEEEEEEEECCCHHHHHHHHHHHHHHHH
PSFVFPFMTRLDGTLMAFAIFALAFVARPVGTAISMAVQRRWGRGTKLTLALFLLGASTA
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
GMAFLPSYNSVGHIAIIALVVLRLGQGVALGGTWDGLPSLLAMSAPPERRGWYAMIGQLG
CEEECCCCCCCHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHCCCCCCCCCHHHHHHHHC
APVGFALAASLFAYLYSNLSVQEFLDWGWRFPFFVAFAINVVALFARLRLIVGQSYTEMM
CCHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
QQRELEPVGALELMRSEGRNVVLGAFAALASFALFHVVTVFPLSWISMYSEQSITHVLGV
HHHCCCCHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QIAGAFCAAVAIAISGRLADRVGRRNTLGAMACLIGVFSLVTPWLLSSGTVGNNIFILVG
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
FVLLGLSYGQASGTVTANFSPRFRYTGAALSADLAWLVGAAFAPLVALGLSAKFGLIAVS
HHHHHCCCCCCCCEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VYLLSGVVCTLLALRINRLIERRE
HHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503 [H]