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The map label for this gene is tam

Identifier: 120610881

GI number: 120610881

Start: 2426737

End: 2427519

Strand: Direct

Name: tam

Synonym: Aave_2207

Alternate gene names: 120610881

Gene position: 2426737-2427519 (Clockwise)

Preceding gene: 120610880

Following gene: 120610882

Centisome position: 45.34

GC content: 72.8

Gene sequence:

>783_bases
ATGCACGACTGGAACCCCGCGCTCTACCGACGCTTCGAGGACGAGCGCACGCGTCCGGCCCATGAACTGCTCGCGCGGGT
GCCGCTGTCCGCTGCTTCCCATGTGGTGGACCTGGGCTGCGGCCCGGGCAATTCCACCGAACTGCTGGCCGTGCGCTTCC
CCGGGGCGCGCGTGACCGGCATCGATACCTCCGCCGCCATGCTGCAGAGCGCCCGCGAGCGCCTGCCGGCGGCGGAATTC
GTCCAGGCCGACATCGCCGCCTGGGCGCCGCAGCCGGGCGAAGCGCCCGACCTGCTCTATGCCAATGCCTCCCTGCAGTG
GGTGGGCGGGCATGAATCCCTCATTCCCCGGCTGTTCGCCGCGCTCGCGCCGGGCGGCGTGCTGGCCATCCAGATGCCGG
ACAACCGTCAGGAGCCCTCGCACCGCACCATGCGCGAGGTGGCCGCCCAGGCGCCCTGGCGCGACGCCATCGGCGACGCG
GCCGCGGTGCGCACGCGCATCCTGGGCATCGCCGACTACTACGACCTGCTGGCGCCCATCGCCCGGAGCGTGGACGTGTG
GCACACCGTGTACCAGCATCCCATGGCCTCGGCCGCCGCCATCGTCGAGTGGGTGAGCGGTACCGGCCTCAAGCCCTTCG
TCGATCCGCTGCCCGAGGCGCAGCGGGCCGGCTTCCTGGCCGCGTACGAGCGCGGCATCGACGCCGCCTATCCCGTGCGG
GCCGACGGGCAGCGCCTGCTCGCCTTCCCGCGCATGTTCATCGTGGCGCGGCGCTCCGCATGA

Upstream 100 bases:

>100_bases
CATCAACAAGACGCTGGCCGAGCTGCAAGGCGAACAGGACGGCGTGAAGCACCTGCTGTAAGGCGGGCCTGCCCGACGGC
TGCACCTGTACCGCGACGCC

Downstream 100 bases:

>100_bases
ACTCCGCCGTGGCTGCTCCTTCCAGGCTCCATCCCGCCGAGGTGCTGCTCGGCGCCCAGGCCGCGGCCGCGCGGCTGCCG
GTGTGCGACCACTACAGCGG

Product: trans-aconitate 2-methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MHDWNPALYRRFEDERTRPAHELLARVPLSAASHVVDLGCGPGNSTELLAVRFPGARVTGIDTSAAMLQSARERLPAAEF
VQADIAAWAPQPGEAPDLLYANASLQWVGGHESLIPRLFAALAPGGVLAIQMPDNRQEPSHRTMREVAAQAPWRDAIGDA
AAVRTRILGIADYYDLLAPIARSVDVWHTVYQHPMASAAAIVEWVSGTGLKPFVDPLPEAQRAGFLAAYERGIDAAYPVR
ADGQRLLAFPRMFIVARRSA

Sequences:

>Translated_260_residues
MHDWNPALYRRFEDERTRPAHELLARVPLSAASHVVDLGCGPGNSTELLAVRFPGARVTGIDTSAAMLQSARERLPAAEF
VQADIAAWAPQPGEAPDLLYANASLQWVGGHESLIPRLFAALAPGGVLAIQMPDNRQEPSHRTMREVAAQAPWRDAIGDA
AAVRTRILGIADYYDLLAPIARSVDVWHTVYQHPMASAAAIVEWVSGTGLKPFVDPLPEAQRAGFLAAYERGIDAAYPVR
ADGQRLLAFPRMFIVARRSA
>Mature_260_residues
MHDWNPALYRRFEDERTRPAHELLARVPLSAASHVVDLGCGPGNSTELLAVRFPGARVTGIDTSAAMLQSARERLPAAEF
VQADIAAWAPQPGEAPDLLYANASLQWVGGHESLIPRLFAALAPGGVLAIQMPDNRQEPSHRTMREVAAQAPWRDAIGDA
AAVRTRILGIADYYDLLAPIARSVDVWHTVYQHPMASAAAIVEWVSGTGLKPFVDPLPEAQRAGFLAAYERGIDAAYPVR
ADGQRLLAFPRMFIVARRSA

Specific function: Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate

COG id: COG4106

COG function: function code R; Trans-aconitate methyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. Tam family

Homologues:

Organism=Escherichia coli, GI1787798, Length=258, Percent_Identity=52.3255813953488, Blast_Score=265, Evalue=2e-72,
Organism=Escherichia coli, GI1786994, Length=122, Percent_Identity=32.7868852459016, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TAM_ACIAC (A1TP97)

Other databases:

- EMBL:   CP000512
- RefSeq:   YP_970559.1
- ProteinModelPortal:   A1TP97
- SMR:   A1TP97
- STRING:   A1TP97
- GeneID:   4667548
- GenomeReviews:   CP000512_GR
- KEGG:   aav:Aave_2207
- NMPDR:   fig|397945.5.peg.1905
- eggNOG:   COG4106
- HOGENOM:   HBG328684
- OMA:   WETTYVH
- PhylomeDB:   A1TP97
- ProtClustDB:   PRK01683
- BioCyc:   AAVE397945:AAVE_2207-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00560
- InterPro:   IPR013216
- InterPro:   IPR023149

Pfam domain/function: PF08241 Methyltransf_11

EC number: =2.1.1.144

Molecular weight: Translated: 28273; Mature: 28273

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHDWNPALYRRFEDERTRPAHELLARVPLSAASHVVDLGCGPGNSTELLAVRFPGARVTG
CCCCCHHHHHHHHHHCCCHHHHHHHHCCHHHHHHEEECCCCCCCCCCEEEEECCCCEEEC
IDTSAAMLQSARERLPAAEFVQADIAAWAPQPGEAPDLLYANASLQWVGGHESLIPRLFA
CCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCEEEECCEEEEECCHHHHHHHHHH
ALAPGGVLAIQMPDNRQEPSHRTMREVAAQAPWRDAIGDAAAVRTRILGIADYYDLLAPI
HHCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARSVDVWHTVYQHPMASAAAIVEWVSGTGLKPFVDPLPEAQRAGFLAAYERGIDAAYPVR
HHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCHHHCCCCHHHHCCHHHHHHHCCCCCCCCC
ADGQRLLAFPRMFIVARRSA
CCCHHHHHHHHHHHHEECCC
>Mature Secondary Structure
MHDWNPALYRRFEDERTRPAHELLARVPLSAASHVVDLGCGPGNSTELLAVRFPGARVTG
CCCCCHHHHHHHHHHCCCHHHHHHHHCCHHHHHHEEECCCCCCCCCCEEEEECCCCEEEC
IDTSAAMLQSARERLPAAEFVQADIAAWAPQPGEAPDLLYANASLQWVGGHESLIPRLFA
CCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCEEEECCEEEEECCHHHHHHHHHH
ALAPGGVLAIQMPDNRQEPSHRTMREVAAQAPWRDAIGDAAAVRTRILGIADYYDLLAPI
HHCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARSVDVWHTVYQHPMASAAAIVEWVSGTGLKPFVDPLPEAQRAGFLAAYERGIDAAYPVR
HHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCHHHCCCCHHHHCCHHHHHHHCCCCCCCCC
ADGQRLLAFPRMFIVARRSA
CCCHHHHHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA