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The map label for this gene is aidB [C]

Identifier: 120610844

GI number: 120610844

Start: 2385296

End: 2387089

Strand: Direct

Name: aidB [C]

Synonym: Aave_2170

Alternate gene names: 120610844

Gene position: 2385296-2387089 (Clockwise)

Preceding gene: 120610843

Following gene: 120610845

Centisome position: 44.56

GC content: 70.62

Gene sequence:

>1794_bases
ATGAGCTACACCGCCCCCGTCAAGGACATGCTGTTCGCCATCGAGCACCTCGCGGGCATCGCGCAGGTCGCCGCGCTGCC
GGGCTTCGAGGAGGCCGGCCTGGACACGGCGCAGGCGGTGCTGGAGGAATGCGCGCGCTTCAACGAGGGCGTGGTGGCGC
CGCTCAACGTGGCGGGCGACCGCAACCCGTCGTCCTGGAAGGACGGCCAGGTGACGACCACGCCGGGCTTCAAGGACGCG
TTCCGGCAGTTCGCGGAGGGCGGCTGGCAGGGCCTGCAGCACCCGGTGGACTTCGGCGGCCAGGGCCTGCCCAAGACCAT
CGGCGCGGCCTGCGCGGAGATGCTCAACAGCGCCAACATGAGCTTCGCGCTGTGCCCGCTGCTGACCGACGGCGCCATCG
AGGCGCTGATCACCGCCGGCAGCGACGCACTCAAGACCACCTACCTGGAAAAGCTGGTGACGGGCGAGTGGACCGGCACC
ATGAACCTGACCGAGCCGCAGGCCGGCTCGGACCTGGCCCTGGTGCGCACGCGCGCCGAGCCGCAGGGCGATGGCACCTA
CAAGGTCTTCGGCACGAAGATCTTCATCACCTACGGCGAGCACGACATGGCGGAGAACATCGTGCACCTGGTGCTGGCCC
GCGTGGCCGGCGCGCCGGAGGGCGTGAAGGGCATCAGCCTGTTCGTGGTGCCGAAGTTCCTGGTGAACGCCGACGGATCC
CTGGGCGCGCGCAACGATGTGCAGTGCGTCTCCATCGAGCACAAGCTCGGCATCAAGGCCTCTCCGACGGCGGTGCTGCA
GTTCGGCGACGCGGGCGGGGCGGTGGGCTACCTCGTCGGCGAGGAGAACCGCGGGCTGGAATACATGTTCATCATGATGA
ACGCGGCACGCTACGCCGTGGGCCTGCAGGGCATCGCGGTGGCCGAGCGCGCCTACCAGCAGGCCGTGCAGTACGCGCGC
GACCGCGTGCAGAGCCGCCCCGTGGACGGCAGCCTGCCGGGCAGCGCGCCCATCATCCACCACCCCGACGTGCGCCGCAT
GCTCATGACCATGCGCGCGCTCACCGAAGGCTGCCGCGCCATGGCCAGCGTGGCCGCCGCGGCCTACGACGCCGCGCACC
ACCATCCCGATGCGGGAGTGCGCAAACAGAACCAGGCGTTCTACGAATTCATGGTGCCGCTCGTGAAGGGCTACAGCACC
GAGATGAGCCTGGAAGTGACCAGCCTGGGCGTGCAGGTGCACGGCGGCATGGGCTTCATCGAGGAGACGGGCGCGGCGCA
GCACTACCGCGACGCGCGCATCCTGCCGATCTACGAAGGCACCACGGCCATCCAGGCCAACGACCTCGTGGGCCGCAAGA
CGGCGCGCGACGGTGCGGCCACGGCGCTCGGCGTCGCCGCGCAGGCCCGCGCAACGGCCGACGAACTGCGCGCGGCCGGT
ACGCCCGAAGCCGGGGCCGTGGCGAAGCGACTGGCCGAGGCCTGCGGTGCCTTCGAGGAAGTGGCGCGCTTCATCGCGTC
GAACACCAAGTCCGACCCCAACGCCGCCTTCGCGGGCAGCGTGCCCTACCTGATGCTGGCCGGCAACCTGGTCGCGGGCT
GGCAGATGGGCCGCGCGCTGCTCAAGGCCCGGGCGCTGCTCGCGGAGGGGCAGGGCGATGCGGCCTTCCTGCAGGCCAAG
GTGGCCACGGCGCGCTTCTATGCCGAACACATCCTGGTGCGCACGAAGGCGCAGCGGGACGCCATCGTCGAAGGCGCGGC
CAGCGTGACGGCGCTCGCGCTGGACGCTTTCTGA

Upstream 100 bases:

>100_bases
CTGCAGGCAGGGCCTCCACGAGGGCATCGCATGCGGTGCCCTTTTTTTTGCCCGGCCCGTCCGGTCCGCGGCCGTTTTCA
TCGATTCCGGAGACATTCCC

Downstream 100 bases:

>100_bases
GCGAACCGCTTCCGCACCCGCTGCCATCGACAGACACCCCAGAACGACAAACCGGAGACTTTCCCATGCGCACCCTGCCG
CCCGTTTTCCAGAAACTTTC

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; BCAD; SCAD [H]

Number of amino acids: Translated: 597; Mature: 596

Protein sequence:

>597_residues
MSYTAPVKDMLFAIEHLAGIAQVAALPGFEEAGLDTAQAVLEECARFNEGVVAPLNVAGDRNPSSWKDGQVTTTPGFKDA
FRQFAEGGWQGLQHPVDFGGQGLPKTIGAACAEMLNSANMSFALCPLLTDGAIEALITAGSDALKTTYLEKLVTGEWTGT
MNLTEPQAGSDLALVRTRAEPQGDGTYKVFGTKIFITYGEHDMAENIVHLVLARVAGAPEGVKGISLFVVPKFLVNADGS
LGARNDVQCVSIEHKLGIKASPTAVLQFGDAGGAVGYLVGEENRGLEYMFIMMNAARYAVGLQGIAVAERAYQQAVQYAR
DRVQSRPVDGSLPGSAPIIHHPDVRRMLMTMRALTEGCRAMASVAAAAYDAAHHHPDAGVRKQNQAFYEFMVPLVKGYST
EMSLEVTSLGVQVHGGMGFIEETGAAQHYRDARILPIYEGTTAIQANDLVGRKTARDGAATALGVAAQARATADELRAAG
TPEAGAVAKRLAEACGAFEEVARFIASNTKSDPNAAFAGSVPYLMLAGNLVAGWQMGRALLKARALLAEGQGDAAFLQAK
VATARFYAEHILVRTKAQRDAIVEGAASVTALALDAF

Sequences:

>Translated_597_residues
MSYTAPVKDMLFAIEHLAGIAQVAALPGFEEAGLDTAQAVLEECARFNEGVVAPLNVAGDRNPSSWKDGQVTTTPGFKDA
FRQFAEGGWQGLQHPVDFGGQGLPKTIGAACAEMLNSANMSFALCPLLTDGAIEALITAGSDALKTTYLEKLVTGEWTGT
MNLTEPQAGSDLALVRTRAEPQGDGTYKVFGTKIFITYGEHDMAENIVHLVLARVAGAPEGVKGISLFVVPKFLVNADGS
LGARNDVQCVSIEHKLGIKASPTAVLQFGDAGGAVGYLVGEENRGLEYMFIMMNAARYAVGLQGIAVAERAYQQAVQYAR
DRVQSRPVDGSLPGSAPIIHHPDVRRMLMTMRALTEGCRAMASVAAAAYDAAHHHPDAGVRKQNQAFYEFMVPLVKGYST
EMSLEVTSLGVQVHGGMGFIEETGAAQHYRDARILPIYEGTTAIQANDLVGRKTARDGAATALGVAAQARATADELRAAG
TPEAGAVAKRLAEACGAFEEVARFIASNTKSDPNAAFAGSVPYLMLAGNLVAGWQMGRALLKARALLAEGQGDAAFLQAK
VATARFYAEHILVRTKAQRDAIVEGAASVTALALDAF
>Mature_596_residues
SYTAPVKDMLFAIEHLAGIAQVAALPGFEEAGLDTAQAVLEECARFNEGVVAPLNVAGDRNPSSWKDGQVTTTPGFKDAF
RQFAEGGWQGLQHPVDFGGQGLPKTIGAACAEMLNSANMSFALCPLLTDGAIEALITAGSDALKTTYLEKLVTGEWTGTM
NLTEPQAGSDLALVRTRAEPQGDGTYKVFGTKIFITYGEHDMAENIVHLVLARVAGAPEGVKGISLFVVPKFLVNADGSL
GARNDVQCVSIEHKLGIKASPTAVLQFGDAGGAVGYLVGEENRGLEYMFIMMNAARYAVGLQGIAVAERAYQQAVQYARD
RVQSRPVDGSLPGSAPIIHHPDVRRMLMTMRALTEGCRAMASVAAAAYDAAHHHPDAGVRKQNQAFYEFMVPLVKGYSTE
MSLEVTSLGVQVHGGMGFIEETGAAQHYRDARILPIYEGTTAIQANDLVGRKTARDGAATALGVAAQARATADELRAAGT
PEAGAVAKRLAEACGAFEEVARFIASNTKSDPNAAFAGSVPYLMLAGNLVAGWQMGRALLKARALLAEGQGDAAFLQAKV
ATARFYAEHILVRTKAQRDAIVEGAASVTALALDAF

Specific function: Has an optimum specificity for 4-carbon length fatty acyl-CoAs [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=443, Percent_Identity=27.313769751693, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI4501857, Length=333, Percent_Identity=27.027027027027, Blast_Score=104, Evalue=3e-22,
Organism=Homo sapiens, GI4501859, Length=447, Percent_Identity=25.9507829977629, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI4557235, Length=386, Percent_Identity=27.720207253886, Blast_Score=100, Evalue=6e-21,
Organism=Homo sapiens, GI76496475, Length=386, Percent_Identity=27.720207253886, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI21361497, Length=359, Percent_Identity=27.0194986072423, Blast_Score=97, Evalue=6e-20,
Organism=Homo sapiens, GI226958412, Length=372, Percent_Identity=25, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI226958414, Length=371, Percent_Identity=25.0673854447439, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI7656849, Length=367, Percent_Identity=25.8855585831063, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI187960098, Length=310, Percent_Identity=26.7741935483871, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI4557231, Length=310, Percent_Identity=27.0967741935484, Blast_Score=85, Evalue=2e-16,
Organism=Escherichia coli, GI87082384, Length=340, Percent_Identity=28.8235294117647, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI87081958, Length=388, Percent_Identity=25.5154639175258, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508101, Length=366, Percent_Identity=28.1420765027322, Blast_Score=113, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI86563383, Length=359, Percent_Identity=28.6908077994429, Blast_Score=108, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI86563381, Length=359, Percent_Identity=28.6908077994429, Blast_Score=108, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71985184, Length=403, Percent_Identity=26.5508684863524, Blast_Score=105, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI17506239, Length=411, Percent_Identity=26.5206812652068, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17505929, Length=367, Percent_Identity=27.5204359673025, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17551932, Length=367, Percent_Identity=25.0681198910082, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17570075, Length=353, Percent_Identity=25.7790368271955, Blast_Score=93, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17533517, Length=366, Percent_Identity=25.1366120218579, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17569725, Length=364, Percent_Identity=25.8241758241758, Blast_Score=87, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17534899, Length=419, Percent_Identity=24.582338902148, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71990804, Length=241, Percent_Identity=28.6307053941909, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17538396, Length=417, Percent_Identity=24.4604316546763, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71985192, Length=249, Percent_Identity=29.718875502008, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI32563615, Length=242, Percent_Identity=28.5123966942149, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI71982178, Length=299, Percent_Identity=25.4180602006689, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI21356377, Length=375, Percent_Identity=30.1333333333333, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI281363737, Length=364, Percent_Identity=27.1978021978022, Blast_Score=103, Evalue=4e-22,
Organism=Drosophila melanogaster, GI21355753, Length=428, Percent_Identity=26.1682242990654, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24666513, Length=380, Percent_Identity=27.3684210526316, Blast_Score=95, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24660351, Length=360, Percent_Identity=25.8333333333333, Blast_Score=90, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24646207, Length=430, Percent_Identity=25.1162790697674, Blast_Score=82, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 62978; Mature: 62847

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYTAPVKDMLFAIEHLAGIAQVAALPGFEEAGLDTAQAVLEECARFNEGVVAPLNVAGD
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHCCCCCEEEEECCCC
RNPSSWKDGQVTTTPGFKDAFRQFAEGGWQGLQHPVDFGGQGLPKTIGAACAEMLNSANM
CCCCCCCCCEEEECCCHHHHHHHHHHCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
SFALCPLLTDGAIEALITAGSDALKTTYLEKLVTGEWTGTMNLTEPQAGSDLALVRTRAE
CEEECCHHCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEECCCCCCCCCEEEEEECCC
PQGDGTYKVFGTKIFITYGEHDMAENIVHLVLARVAGAPEGVKGISLFVVPKFLVNADGS
CCCCCEEEEEEEEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHCCCCC
LGARNDVQCVSIEHKLGIKASPTAVLQFGDAGGAVGYLVGEENRGLEYMFIMMNAARYAV
CCCCCCCEEEEEHHHCCCCCCCCEEEEECCCCCEEEEEECCCCCCCEEEEEEEHHHHHHH
GLQGIAVAERAYQQAVQYARDRVQSRPVDGSLPGSAPIIHHPDVRRMLMTMRALTEGCRA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHH
MASVAAAAYDAAHHHPDAGVRKQNQAFYEFMVPLVKGYSTEMSLEVTSLGVQVHGGMGFI
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEEECCCCCH
EETGAAQHYRDARILPIYEGTTAIQANDLVGRKTARDGAATALGVAAQARATADELRAAG
HHCCCHHHHCCCEEEEEECCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHCHHHHHCCC
TPEAGAVAKRLAEACGAFEEVARFIASNTKSDPNAAFAGSVPYLMLAGNLVAGWQMGRAL
CCCHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCEECCCCCEEEECCCHHHHHHHHHHH
LKARALLAEGQGDAAFLQAKVATARFYAEHILVRTKAQRDAIVEGAASVTALALDAF
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHEEEECC
>Mature Secondary Structure 
SYTAPVKDMLFAIEHLAGIAQVAALPGFEEAGLDTAQAVLEECARFNEGVVAPLNVAGD
CCCCCHHHHHHHHHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHCCCCCEEEEECCCC
RNPSSWKDGQVTTTPGFKDAFRQFAEGGWQGLQHPVDFGGQGLPKTIGAACAEMLNSANM
CCCCCCCCCEEEECCCHHHHHHHHHHCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
SFALCPLLTDGAIEALITAGSDALKTTYLEKLVTGEWTGTMNLTEPQAGSDLALVRTRAE
CEEECCHHCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEECCCCCCCCCEEEEEECCC
PQGDGTYKVFGTKIFITYGEHDMAENIVHLVLARVAGAPEGVKGISLFVVPKFLVNADGS
CCCCCEEEEEEEEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHCCCCC
LGARNDVQCVSIEHKLGIKASPTAVLQFGDAGGAVGYLVGEENRGLEYMFIMMNAARYAV
CCCCCCCEEEEEHHHCCCCCCCCEEEEECCCCCEEEEEECCCCCCCEEEEEEEHHHHHHH
GLQGIAVAERAYQQAVQYARDRVQSRPVDGSLPGSAPIIHHPDVRRMLMTMRALTEGCRA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHH
MASVAAAAYDAAHHHPDAGVRKQNQAFYEFMVPLVKGYSTEMSLEVTSLGVQVHGGMGFI
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEEECCCCCH
EETGAAQHYRDARILPIYEGTTAIQANDLVGRKTARDGAATALGVAAQARATADELRAAG
HHCCCHHHHCCCEEEEEECCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHCHHHHHCCC
TPEAGAVAKRLAEACGAFEEVARFIASNTKSDPNAAFAGSVPYLMLAGNLVAGWQMGRAL
CCCHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCEECCCCCEEEECCCHHHHHHHHHHH
LKARALLAEGQGDAAFLQAKVATARFYAEHILVRTKAQRDAIVEGAASVTALALDAF
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8399220; 7857927 [H]