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The map label for this gene is gbpR [H]

Identifier: 120610762

GI number: 120610762

Start: 2287172

End: 2288098

Strand: Direct

Name: gbpR [H]

Synonym: Aave_2084

Alternate gene names: 120610762

Gene position: 2287172-2288098 (Clockwise)

Preceding gene: 120610757

Following gene: 120610766

Centisome position: 42.73

GC content: 72.6

Gene sequence:

>927_bases
ATGCCCAGGATCGATCGCGTGCTGCGTTCCAACCTCAAGCTGAGGCACCTGCAGATGCTGGTCGCGCTCGACCAGTTCCG
CCACGTCGGCCGCGCGGCGGAGTTCCTCTCCGTCACGCAGCCTGCCGTCTCCAAGACGCTGGCCGAGATCGAGCGCATGT
TCGGCCTGCCCCTGTTCGAGCGCTCCACCCGCGGCACCGAGCCCACCGCCGCGGGCGCGAGCGTGGTGCGCTTCGCGCGT
TCCGTGCTCGCCGGCTACGAGCGCACGCGCGACGAGATCGCCGCCGAGGCCAGCGGCGCCCGCGGCCGCACCAGCGTGGG
CGCCATGGTGGCCGCCACCCCGGTGCTGCTCGCGCAGGCCGTGGAGCGGCTCAAGGCGCGCTCGCCCCACGTGACCGTCC
TCATCGAGGAGGGCGACCTCACCCGCCTGCTGCCCAGGCTGCGGCTGGGCGAGCTCGACCTGTTCGTCGGCCGCCTGGAG
CCCGGATATGCCTCGCCCGACCTGGAAACCGAGGCACTCTACGACGACCCCATGGTCGCCGTCGTGCGCCCCGGCCATCC
CCTGGCCCGCAGGCGCCAGCCCCGCTGGTCCGACATCGCCGCACAGCCCTGCGTGCTGCCCCCGCCCTGGGCCTCGCTGC
GCGTGAAGCTGGAGCAGCAGTTCTTTGCCCACGGCCTGCACCCGCCCGCCGACATCGTCGAATCGGCCTCGTTCCTGTCG
CAGATCACCTTCGTCCACCAGCGCGGCGCCGTCGCCTTCATGGCGGGCACCGTGGCAAGGCATTTCGCGCAGCAGGGCCT
GCTGGCGGTGCTCAGGCTGCCCGTGCCGGTGGAGCTGCCGCCGGTGGGGATCATCCGGATGCGGGGGCAGGAGGGCACGG
CGGTGACGGAGGCGCTGGTGGAATGCCTGAGGGAGACGGGCAAGTGA

Upstream 100 bases:

>100_bases
TTTATCGTGGGTGAGGGCTGCCTCCATTGTTCAGAAGCGGGACATGCCAATCCAATGAAAATACGGACTGCCTTCATAAC
CTCCAAGGAATGTCCGGAAA

Downstream 100 bases:

>100_bases
CTGCAGGGCAGGGCGGCCGGGGCGCGGAGACGGGAGTGCGCCGGCAACGACGCATCAACGGCGATTCAACGAATCACCGT
TGCCGTCGCTTCCCAGCGGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Galactose-binding protein regulator; GBP regulator [H]

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MPRIDRVLRSNLKLRHLQMLVALDQFRHVGRAAEFLSVTQPAVSKTLAEIERMFGLPLFERSTRGTEPTAAGASVVRFAR
SVLAGYERTRDEIAAEASGARGRTSVGAMVAATPVLLAQAVERLKARSPHVTVLIEEGDLTRLLPRLRLGELDLFVGRLE
PGYASPDLETEALYDDPMVAVVRPGHPLARRRQPRWSDIAAQPCVLPPPWASLRVKLEQQFFAHGLHPPADIVESASFLS
QITFVHQRGAVAFMAGTVARHFAQQGLLAVLRLPVPVELPPVGIIRMRGQEGTAVTEALVECLRETGK

Sequences:

>Translated_308_residues
MPRIDRVLRSNLKLRHLQMLVALDQFRHVGRAAEFLSVTQPAVSKTLAEIERMFGLPLFERSTRGTEPTAAGASVVRFAR
SVLAGYERTRDEIAAEASGARGRTSVGAMVAATPVLLAQAVERLKARSPHVTVLIEEGDLTRLLPRLRLGELDLFVGRLE
PGYASPDLETEALYDDPMVAVVRPGHPLARRRQPRWSDIAAQPCVLPPPWASLRVKLEQQFFAHGLHPPADIVESASFLS
QITFVHQRGAVAFMAGTVARHFAQQGLLAVLRLPVPVELPPVGIIRMRGQEGTAVTEALVECLRETGK
>Mature_307_residues
PRIDRVLRSNLKLRHLQMLVALDQFRHVGRAAEFLSVTQPAVSKTLAEIERMFGLPLFERSTRGTEPTAAGASVVRFARS
VLAGYERTRDEIAAEASGARGRTSVGAMVAATPVLLAQAVERLKARSPHVTVLIEEGDLTRLLPRLRLGELDLFVGRLEP
GYASPDLETEALYDDPMVAVVRPGHPLARRRQPRWSDIAAQPCVLPPPWASLRVKLEQQFFAHGLHPPADIVESASFLSQ
ITFVHQRGAVAFMAGTVARHFAQQGLLAVLRLPVPVELPPVGIIRMRGQEGTAVTEALVECLRETGK

Specific function: Does not seem to be required for sbpA expression [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081904, Length=304, Percent_Identity=25.6578947368421, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1790399, Length=208, Percent_Identity=28.3653846153846, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787601, Length=299, Percent_Identity=24.4147157190635, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788887, Length=182, Percent_Identity=30.2197802197802, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI157672245, Length=287, Percent_Identity=25.4355400696864, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI145693105, Length=209, Percent_Identity=23.9234449760766, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789506, Length=171, Percent_Identity=29.8245614035088, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787879, Length=205, Percent_Identity=27.3170731707317, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787530, Length=219, Percent_Identity=25.1141552511416, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1788748, Length=311, Percent_Identity=23.7942122186495, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790208, Length=194, Percent_Identity=26.8041237113402, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1789204, Length=288, Percent_Identity=26.0416666666667, Blast_Score=62, Evalue=7e-11,
Organism=Escherichia coli, GI87081684, Length=195, Percent_Identity=23.5897435897436, Blast_Score=61, Evalue=1e-10,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33784; Mature: 33653

Theoretical pI: Translated: 10.26; Mature: 10.26

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRIDRVLRSNLKLRHLQMLVALDQFRHVGRAAEFLSVTQPAVSKTLAEIERMFGLPLFE
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
RSTRGTEPTAAGASVVRFARSVLAGYERTRDEIAAEASGARGRTSVGAMVAATPVLLAQA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
VERLKARSPHVTVLIEEGDLTRLLPRLRLGELDLFVGRLEPGYASPDLETEALYDDPMVA
HHHHHCCCCCEEEEEECCCHHHHHHHHCCCCHHHEEECCCCCCCCCCCCCHHHCCCCEEE
VVRPGHPLARRRQPRWSDIAAQPCVLPPPWASLRVKLEQQFFAHGLHPPADIVESASFLS
EECCCCCHHHCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
QITFVHQRGAVAFMAGTVARHFAQQGLLAVLRLPVPVELPPVGIIRMRGQEGTAVTEALV
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHH
ECLRETGK
HHHHHHCC
>Mature Secondary Structure 
PRIDRVLRSNLKLRHLQMLVALDQFRHVGRAAEFLSVTQPAVSKTLAEIERMFGLPLFE
CHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
RSTRGTEPTAAGASVVRFARSVLAGYERTRDEIAAEASGARGRTSVGAMVAATPVLLAQA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
VERLKARSPHVTVLIEEGDLTRLLPRLRLGELDLFVGRLEPGYASPDLETEALYDDPMVA
HHHHHCCCCCEEEEEECCCHHHHHHHHCCCCHHHEEECCCCCCCCCCCCCHHHCCCCEEE
VVRPGHPLARRRQPRWSDIAAQPCVLPPPWASLRVKLEQQFFAHGLHPPADIVESASFLS
EECCCCCHHHCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
QITFVHQRGAVAFMAGTVARHFAQQGLLAVLRLPVPVELPPVGIIRMRGQEGTAVTEALV
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHH
ECLRETGK
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10361275 [H]