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The map label for this gene is yegE [C]

Identifier: 120610722

GI number: 120610722

Start: 2229741

End: 2231069

Strand: Direct

Name: yegE [C]

Synonym: Aave_2043

Alternate gene names: 120610722

Gene position: 2229741-2231069 (Clockwise)

Preceding gene: 120610721

Following gene: 120610726

Centisome position: 41.66

GC content: 68.02

Gene sequence:

>1329_bases
ATGACGCCGAACGAATTGCCGTTGGATGGCACGCTGTCCGCCGTCGGGACGCCCCCCGGGCTGCCGGATTCCGACATGTT
GCAGATACTCACGCGCAACGTGGGCGCCACGGTGGCCGTGGTCAGCCGCGCGCTGCGCGTCGTTTACGTGAACGACGAAT
ACGCGCGCTGGTTCCGGGCCGCGCCCGAGGCCATCGTCGGCAAGAGCCTGATCGAGCTCTATGGCGAATACAACTATTCG
CGCTTCATGCCTTACGTGCAGCGTGTGCTGGCCGGAGAGCGGGTGAGCTACCAGCGGCTGGTACTCGATCCGGAGGGGCG
CGAATCCTGGCGCACCATCTGCGTATCGCCCTGGCGGGACGCGGGCGGCGGCATCGCCGGCTTCGTCACGGCCGCACTGG
ACGTGGACGAACTCCAGGTGGCCATGAACGCGCTGCGCGCCGCCAACCAGCGCCTGTCCTCGCACATGGACAACAGTCCG
CTCGCCGTGCTGGAAATGGACGACCAATTGCGCGTGCTGCGTTGCTCGCGCCGCGCCATCGAACTCATGGGCTGGCAGGA
TCTCGTCCAGGTCGAATGCCGCCGCCTGCACGAGCTGCCCGGCACCTCGGCCATGGAGCAGCACCTGTCGCAGGCCTTCT
CGGACCTGCGTTCGGGCCGCACCACGCGCAACCGGGTGGAGTCCTGCCTGCGCCGGGCCGATGGATCGGAAGTGCATTGC
GAGTGGTTCAGCTCCGCGCTGACCGACGAAGGCGGCCGCGTCACGTCGATCATGTCGCTCGTGCAGGACATTTCCGCGAA
GATCGAGATCGCGCGCCAGCAGCATTACCTCGCCAACCACGACTCGCTCACCGGCCTGCAGAACCGATCGGCCTTCCAGA
GCCGCTTCGAGCATTCCCTCGCCCGGGTGCGCTCGCGAGGAGGCGCGGTGGCGCTGCTGTTCATCGACCTGGACGGCTTC
AAGAAAATCAACGATGGGCACGGCCACAAGGTGGGCGACGAGGTGCTGCGCTGCGTGGCGCGCCGGCTGGCGCATGCCGT
GCGCGGCAGCGACACCGTGGCGCGTCTGGGCGGCGACGAGTTCCTCGTGATGCTCGACACCGGGGTGGAGGCGGATCTGG
TCGGCCACATCGGGGCGCGCATCATCTCCGCGCTGGCCGAACCCATGGAAGTGGACGGTCATGCCGTGCGCGTGGGCGCG
AGCATCGGTGTGGCCATGCACCCCCCGCTGGAGGGCGACATCGAATTGCTCATGACCCAGGCCGACCAGGCCATGTACGC
CGCCAAGCGTACCGGCCGCGGCTGCATGCGCTACGCGGGCCAGGGCTGA

Upstream 100 bases:

>100_bases
CATCGCCGCAAGGGGATGAAGCAGGCTGTTGCCGGGCCTGCCGGCCGCGCCGCGCCAGCGGGCAGCCGGCGCCCCCCGGG
GTACGAGGGACGAGTTGGCT

Downstream 100 bases:

>100_bases
AGGGCGGGGGGACGCCCGCCCCGCGTCCGCGCCTACGGCTTCACGCTCTGCGCGAAGTGGAAGAAGTTGTCCGGATCGTA
GGCCCGCTTGACGCCCTGGA

Product: PAS/PAC sensor-containing diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MTPNELPLDGTLSAVGTPPGLPDSDMLQILTRNVGATVAVVSRALRVVYVNDEYARWFRAAPEAIVGKSLIELYGEYNYS
RFMPYVQRVLAGERVSYQRLVLDPEGRESWRTICVSPWRDAGGGIAGFVTAALDVDELQVAMNALRAANQRLSSHMDNSP
LAVLEMDDQLRVLRCSRRAIELMGWQDLVQVECRRLHELPGTSAMEQHLSQAFSDLRSGRTTRNRVESCLRRADGSEVHC
EWFSSALTDEGGRVTSIMSLVQDISAKIEIARQQHYLANHDSLTGLQNRSAFQSRFEHSLARVRSRGGAVALLFIDLDGF
KKINDGHGHKVGDEVLRCVARRLAHAVRGSDTVARLGGDEFLVMLDTGVEADLVGHIGARIISALAEPMEVDGHAVRVGA
SIGVAMHPPLEGDIELLMTQADQAMYAAKRTGRGCMRYAGQG

Sequences:

>Translated_442_residues
MTPNELPLDGTLSAVGTPPGLPDSDMLQILTRNVGATVAVVSRALRVVYVNDEYARWFRAAPEAIVGKSLIELYGEYNYS
RFMPYVQRVLAGERVSYQRLVLDPEGRESWRTICVSPWRDAGGGIAGFVTAALDVDELQVAMNALRAANQRLSSHMDNSP
LAVLEMDDQLRVLRCSRRAIELMGWQDLVQVECRRLHELPGTSAMEQHLSQAFSDLRSGRTTRNRVESCLRRADGSEVHC
EWFSSALTDEGGRVTSIMSLVQDISAKIEIARQQHYLANHDSLTGLQNRSAFQSRFEHSLARVRSRGGAVALLFIDLDGF
KKINDGHGHKVGDEVLRCVARRLAHAVRGSDTVARLGGDEFLVMLDTGVEADLVGHIGARIISALAEPMEVDGHAVRVGA
SIGVAMHPPLEGDIELLMTQADQAMYAAKRTGRGCMRYAGQG
>Mature_441_residues
TPNELPLDGTLSAVGTPPGLPDSDMLQILTRNVGATVAVVSRALRVVYVNDEYARWFRAAPEAIVGKSLIELYGEYNYSR
FMPYVQRVLAGERVSYQRLVLDPEGRESWRTICVSPWRDAGGGIAGFVTAALDVDELQVAMNALRAANQRLSSHMDNSPL
AVLEMDDQLRVLRCSRRAIELMGWQDLVQVECRRLHELPGTSAMEQHLSQAFSDLRSGRTTRNRVESCLRRADGSEVHCE
WFSSALTDEGGRVTSIMSLVQDISAKIEIARQQHYLANHDSLTGLQNRSAFQSRFEHSLARVRSRGGAVALLFIDLDGFK
KINDGHGHKVGDEVLRCVARRLAHAVRGSDTVARLGGDEFLVMLDTGVEADLVGHIGARIISALAEPMEVDGHAVRVGAS
IGVAMHPPLEGDIELLMTQADQAMYAAKRTGRGCMRYAGQG

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=310, Percent_Identity=33.5483870967742, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1787541, Length=172, Percent_Identity=35.4651162790698, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI145693134, Length=186, Percent_Identity=36.0215053763441, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87081881, Length=230, Percent_Identity=34.3478260869565, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1786584, Length=177, Percent_Identity=32.2033898305085, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787816, Length=167, Percent_Identity=34.1317365269461, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1788956, Length=152, Percent_Identity=40.1315789473684, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1787262, Length=197, Percent_Identity=27.9187817258883, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87082007, Length=165, Percent_Identity=34.5454545454545, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87081977, Length=151, Percent_Identity=35.7615894039735, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787802, Length=186, Percent_Identity=31.1827956989247, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788085, Length=205, Percent_Identity=28.780487804878, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87081974, Length=124, Percent_Identity=31.4516129032258, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787056, Length=157, Percent_Identity=33.7579617834395, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT; PF00989 PAS [H]

EC number: NA

Molecular weight: Translated: 48549; Mature: 48418

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPNELPLDGTLSAVGTPPGLPDSDMLQILTRNVGATVAVVSRALRVVYVNDEYARWFRA
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHEEEEECCHHHHHHHH
APEAIVGKSLIELYGEYNYSRFMPYVQRVLAGERVSYQRLVLDPEGRESWRTICVSPWRD
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHEEECCCCCC
AGGGIAGFVTAALDVDELQVAMNALRAANQRLSSHMDNSPLAVLEMDDQLRVLRCSRRAI
CCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHH
ELMGWQDLVQVECRRLHELPGTSAMEQHLSQAFSDLRSGRTTRNRVESCLRRADGSEVHC
HHHCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEHH
EWFSSALTDEGGRVTSIMSLVQDISAKIEIARQQHYLANHDSLTGLQNRSAFQSRFEHSL
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
ARVRSRGGAVALLFIDLDGFKKINDGHGHKVGDEVLRCVARRLAHAVRGSDTVARLGGDE
HHHHHCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCE
FLVMLDTGVEADLVGHIGARIISALAEPMEVDGHAVRVGASIGVAMHPPLEGDIELLMTQ
EEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCCCCCCHHHHHHH
ADQAMYAAKRTGRGCMRYAGQG
HHHHHHHHHHCCCHHHHHCCCC
>Mature Secondary Structure 
TPNELPLDGTLSAVGTPPGLPDSDMLQILTRNVGATVAVVSRALRVVYVNDEYARWFRA
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHEEEEECCHHHHHHHH
APEAIVGKSLIELYGEYNYSRFMPYVQRVLAGERVSYQRLVLDPEGRESWRTICVSPWRD
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHEEECCCCCC
AGGGIAGFVTAALDVDELQVAMNALRAANQRLSSHMDNSPLAVLEMDDQLRVLRCSRRAI
CCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHH
ELMGWQDLVQVECRRLHELPGTSAMEQHLSQAFSDLRSGRTTRNRVESCLRRADGSEVHC
HHHCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEHH
EWFSSALTDEGGRVTSIMSLVQDISAKIEIARQQHYLANHDSLTGLQNRSAFQSRFEHSL
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
ARVRSRGGAVALLFIDLDGFKKINDGHGHKVGDEVLRCVARRLAHAVRGSDTVARLGGDE
HHHHHCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCE
FLVMLDTGVEADLVGHIGARIISALAEPMEVDGHAVRVGASIGVAMHPPLEGDIELLMTQ
EEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCCCCCCHHHHHHH
ADQAMYAAKRTGRGCMRYAGQG
HHHHHHHHHHCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]