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The map label for this gene is uppP

Identifier: 120610721

GI number: 120610721

Start: 2228683

End: 2229507

Strand: Direct

Name: uppP

Synonym: Aave_2042

Alternate gene names: 120610721

Gene position: 2228683-2229507 (Clockwise)

Preceding gene: 120610720

Following gene: 120610722

Centisome position: 41.64

GC content: 67.27

Gene sequence:

>825_bases
GTGGATTTCATCTTGCTGGCCAAGGCCGCCGTCATGGGCGTGGTCGAGGGCCTGACCGAGTTCCTCCCCGTCTCCTCCAC
CGGCCACCTGATCCTCGCGGGCGCGCTGCTCGGCTTCGACGACGACAAGGCCAAGGTATTCGACATCGCCATCCAGACCG
GCGCGATCTTCGCGGTCGTTCTGGTGTATTGGCAGAAGATCCGCGAGACCCTGGTGGCGTTGCCCACCCAGCCCCGGGCC
CGGCGCTTCGCGCTGAACGTGCTCATCGGCTTCCTGCCGGCCGTGGTGCTGGCGCTGATCTTCGGCAAGGCGATCAAGGC
GCACCTCTTCACGCCGGTGGTCGTGGCATCCACCTTCATCCTGGGCGGCTTCGTCATCCTCTGGGCCGAACGGCGGGCGC
CCGGCGCCGTGCGCGTGGACTCCGTGGACGACATGACGCCCCTGGACGCGCTGAAGGTCGGGCTCGTGCAGTGCCTGGCC
ATGGTGCCGGGCACGAGCCGCAGCGGCGCCACCATCATCGGCGGGATGCTGCTGGGCCTCTCGCGCAAGGCCGCCACCGA
TTTCTCGTTCTTCCTGGCGATCCCCACGCTGATCGGCGCGGGCGTGTACAGCCTCTACAAGGAGCGGCACCTGCTGTCGA
TGGCCGACCTGCCGCTGTTCGCGGTGGGCCTGCTGTTCTCGTTCGTGAGCGCCTGGCTGTGCGTGCGCTGGCTGCTGCGC
TACATCAGTACCCACAGTTTCGTGCCGTTCGCCTATTACCGCATCGCTTTCGGTATCGTGGTGCTCGCCACGGCCTGGAC
CGGCTGGGTGCACTGGGGAGAATGA

Upstream 100 bases:

>100_bases
CCCCTGGATGGACGGCGCCGCCGCGGCCACGGCCGGGCAGGGTGCTGCCGAGCCCCGATAATCCGCGGCTGCTTTCCCCT
CCCAACGAAAAAGGATTTCC

Downstream 100 bases:

>100_bases
CCCCGTGCGCCAGCGTGGCTGGCGATCCCAGATGGTGGGATGGTTCATATCACTGCATAGCAAATGATGCTATGAAAAAA
AGAAAGTGATAAGCTGCCGC

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MDFILLAKAAVMGVVEGLTEFLPVSSTGHLILAGALLGFDDDKAKVFDIAIQTGAIFAVVLVYWQKIRETLVALPTQPRA
RRFALNVLIGFLPAVVLALIFGKAIKAHLFTPVVVASTFILGGFVILWAERRAPGAVRVDSVDDMTPLDALKVGLVQCLA
MVPGTSRSGATIIGGMLLGLSRKAATDFSFFLAIPTLIGAGVYSLYKERHLLSMADLPLFAVGLLFSFVSAWLCVRWLLR
YISTHSFVPFAYYRIAFGIVVLATAWTGWVHWGE

Sequences:

>Translated_274_residues
MDFILLAKAAVMGVVEGLTEFLPVSSTGHLILAGALLGFDDDKAKVFDIAIQTGAIFAVVLVYWQKIRETLVALPTQPRA
RRFALNVLIGFLPAVVLALIFGKAIKAHLFTPVVVASTFILGGFVILWAERRAPGAVRVDSVDDMTPLDALKVGLVQCLA
MVPGTSRSGATIIGGMLLGLSRKAATDFSFFLAIPTLIGAGVYSLYKERHLLSMADLPLFAVGLLFSFVSAWLCVRWLLR
YISTHSFVPFAYYRIAFGIVVLATAWTGWVHWGE
>Mature_274_residues
MDFILLAKAAVMGVVEGLTEFLPVSSTGHLILAGALLGFDDDKAKVFDIAIQTGAIFAVVLVYWQKIRETLVALPTQPRA
RRFALNVLIGFLPAVVLALIFGKAIKAHLFTPVVVASTFILGGFVILWAERRAPGAVRVDSVDDMTPLDALKVGLVQCLA
MVPGTSRSGATIIGGMLLGLSRKAATDFSFFLAIPTLIGAGVYSLYKERHLLSMADLPLFAVGLLFSFVSAWLCVRWLLR
YISTHSFVPFAYYRIAFGIVVLATAWTGWVHWGE

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=253, Percent_Identity=47.0355731225296, Blast_Score=222, Evalue=2e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_ACIAC (A1TNT7)

Other databases:

- EMBL:   CP000512
- RefSeq:   YP_970399.1
- STRING:   A1TNT7
- GeneID:   4669115
- GenomeReviews:   CP000512_GR
- KEGG:   aav:Aave_2042
- NMPDR:   fig|397945.5.peg.1765
- eggNOG:   COG1968
- HOGENOM:   HBG391969
- OMA:   LVQCLAM
- PhylomeDB:   A1TNT7
- ProtClustDB:   PRK00281
- BioCyc:   AAVE397945:AAVE_2042-MONOMER
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 29732; Mature: 29732

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x12fecc6c)-; HASH(0x13dee720)-; HASH(0x142bf518)-; HASH(0x136317b4)-; HASH(0x143200f4)-; HASH(0x14270754)-; HASH(0x1426c174)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFILLAKAAVMGVVEGLTEFLPVSSTGHLILAGALLGFDDDKAKVFDIAIQTGAIFAVV
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHCCCCCCCCEEEEHHHHHHHHHHH
LVYWQKIRETLVALPTQPRARRFALNVLIGFLPAVVLALIFGKAIKAHLFTPVVVASTFI
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGGFVILWAERRAPGAVRVDSVDDMTPLDALKVGLVQCLAMVPGTSRSGATIIGGMLLGL
HHHHHHEEECCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHC
SRKAATDFSFFLAIPTLIGAGVYSLYKERHLLSMADLPLFAVGLLFSFVSAWLCVRWLLR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YISTHSFVPFAYYRIAFGIVVLATAWTGWVHWGE
HHHHCCCHHHHHHHHHHHHHHHHHHHHCCEECCH
>Mature Secondary Structure
MDFILLAKAAVMGVVEGLTEFLPVSSTGHLILAGALLGFDDDKAKVFDIAIQTGAIFAVV
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHCCCCCCCCEEEEHHHHHHHHHHH
LVYWQKIRETLVALPTQPRARRFALNVLIGFLPAVVLALIFGKAIKAHLFTPVVVASTFI
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGGFVILWAERRAPGAVRVDSVDDMTPLDALKVGLVQCLAMVPGTSRSGATIIGGMLLGL
HHHHHHEEECCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHC
SRKAATDFSFFLAIPTLIGAGVYSLYKERHLLSMADLPLFAVGLLFSFVSAWLCVRWLLR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YISTHSFVPFAYYRIAFGIVVLATAWTGWVHWGE
HHHHCCCHHHHHHHHHHHHHHHHHHHHCCEECCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA