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The map label for this gene is aquIMA [H]

Identifier: 120610363

GI number: 120610363

Start: 1836299

End: 1838431

Strand: Reverse

Name: aquIMA [H]

Synonym: Aave_1680

Alternate gene names: 120610363

Gene position: 1838431-1836299 (Counterclockwise)

Preceding gene: 120610364

Following gene: 120610362

Centisome position: 34.35

GC content: 71.82

Gene sequence:

>2133_bases
ATGAAGCGTGACGCCTTCACCCTCCCGCTCGCATTCCCCGGCGAGCTGATCATCGACAACTTCGCCGGCGGCGGCGGCAC
GTCAACCGGGCTGGAGGCCGCATTCGGCAGGCCCGTGGACATCGCCATCAACCACGACCCCGAGGCGCTGGCCATGCACG
CCATCAACCACCCGCACACCCAGCACCTGTGCGAGAGCGTGTGGGAGGTGGATCCCATCGCCGTGACGGGGAACCAGCCG
GTGGGCCTCGTGTGGCTGTCGCCGGACTGCAAGCACTTCAGCAAGGCCAAGGGCGGCACGCCCGTGGCGAAGCACATCCG
CGGCCTGGCCTGGGTGGGCATGCGCTGGGTGGCGCTCTGCAAGCCCCGCGTGCTGATGTTGGAGAACGTCGAGGAATTCC
AGACCTGGGGCCCGCTGCTGGTGGGAGCCGACGGCACCGCCCGCCCGGACCCCGCGCGGAAGGGGAAGACGTTCCAGAGC
TTCGTGCGGCAGCTGCGCGCGCACGGGTATGCCGTGGACTGGCGCGAGCTGCGCGCGTGCGACAACGGCGCGCCGACGAT
TCGCAAGCGCCTGTTCTTGATCGCGCGCCGCGACGGCCTGCCAATCCAGTGGCCCGAGCAGACGCACGCCGCGCCCACCG
ATCGCCGCGTGCTCGCCGGCAAGCTGGCGCCCTATCGCACGGCGGCCGACTGCATCGACTTCAGCCTGGAGGCGGCCAGC
ATCTTCGACCGCCAGCGGCCGCTGGCCACCAACACCCAGCGCCGCGTCGCGAAGGGCCTGTTCCGGCACGTCCTGACCAG
CGCGTCGCCCTTCATCGTGGGCGTGGGCGGCCGCATGGGCCAGAGCCCCGCGCGCAGCGTGCACGCTCCCGCGCAGACCA
TCACGGCCAAGGCGGACAGCTGCATCGCGCAACCGGTGCTGACCCCCTACATGGTCAACACCCGCAACGGTGAGCGCGCG
GGCCAGCAGCCGCGCGTGCGCGGCGCCGAGGAGCCGTATTGGACGGTGACGGGCCTGGGATCGCAGGGCGCGCTCGCGGC
GCCGGTCATGACGCCATTCCTCACCGAGCACGCCAACAGCAGCAACCAACGGACCATGGCGGCCGACGAGCCCCTGCGCA
CGATCTGCGCCCAGGTGAAGGGCGGCCACTTCTCGGCCGTGGCACCGGTGATCGCCCCGCTCCGCGGCACGAGCGAGCAG
CACCTGCAGGGTGACGACACCCGGGAGCCGCTGTCCACCGTATCAGCCGGCGGCACGCACCACGCCCTGGCCGGCGCCGT
GCTGGCGGCCGCGATCGTCACCAACACGACCGGGCACCCGGGCGCGACGGCGGACACGCCGCTGGCCACCATCACCACGG
GCGGCCACCACGCCATGGCGGCGATGCACATCACGAAGTTCAACACCGGGTCCGTGGGCTCGGGCATGGACGAGCCCCTG
CGTACCGTGACAGCCGGCGGGACACCCAGCCGCCCCAGCACCGGCATTCAGATGGGCATGGTCGCCGCGATGCTGGAGCA
GGCCAACGGCGGTTTCTACGACGGCGACGGCCGGCCCGTCGGAGCCCCGGCCAGCACCATCACCAGCAGCGGAGCGCAGC
AGCGCCTGGTGACGGCCTACCTGGTGAAGTACTACAGCGAGGGCGGCCAGGACAGCGCCTGCGGCGCGCCGATGCACACC
GTGCCGACGAAGGCGCGCATGGGCCTCGTGCAGACCGTGCAGGTGCCAGCCGACTGCCTGGCGCCGGAACACCGGGCCCG
CGCGCGGCAGTGCGCCGAGCTGCTGCACACGCACCTGCCCGAGCAGTTTCCCGACCCGGCCGCCCTGGTGCTGATGCACC
ACGCGGGCCAGTGGTGGGTGCTGGTGGACATCACGCTGCGCATGCTGAAGCCGGTGGAGCTGTTCCGCGCCCAGGGCTTC
CCCGAGGACTACGTGATCCACGAGATCCCGGACCCTGCCCTGCTCTTCGCGGGCGGAAAGCAGGCAGCCCACCCGCTGGA
GGTGCAGCGCATCCCGCTCACCGCCACGGCGCAGGTCCGCATGTGCGGGAACAGCGTCAGCCCGCCGCAGGCCGAGGCGC
TGGTCCGCGCGAACTTCGGCCACGAGACGGCCTGGATGGCCGTCGCCGCATAA

Upstream 100 bases:

>100_bases
GGCATTCATTTTTACCCTCTCTGTTGTAGAGCGCCATATTACTTCGCAACCCAGGCCCGTCGCCTCGCAACCGCGGGCCT
TTTTCGTTTCTGGAGCCCGC

Downstream 100 bases:

>100_bases
CCCCGCCCGCACCAGCGGGCATTTTTTTGGAAGCCCCATGTCCCAAGCCACCACCGATCAGCCCTATACGCCGCCGGACG
GCCGCGTGGAGCCCTTCCCG

Product: C-5 cytosine-specific DNA methylase

Products: NA

Alternate protein names: M.AquI subunit alpha; M.AquiA; Cytosine-specific methyltransferase AquI subunit alpha [H]

Number of amino acids: Translated: 710; Mature: 710

Protein sequence:

>710_residues
MKRDAFTLPLAFPGELIIDNFAGGGGTSTGLEAAFGRPVDIAINHDPEALAMHAINHPHTQHLCESVWEVDPIAVTGNQP
VGLVWLSPDCKHFSKAKGGTPVAKHIRGLAWVGMRWVALCKPRVLMLENVEEFQTWGPLLVGADGTARPDPARKGKTFQS
FVRQLRAHGYAVDWRELRACDNGAPTIRKRLFLIARRDGLPIQWPEQTHAAPTDRRVLAGKLAPYRTAADCIDFSLEAAS
IFDRQRPLATNTQRRVAKGLFRHVLTSASPFIVGVGGRMGQSPARSVHAPAQTITAKADSCIAQPVLTPYMVNTRNGERA
GQQPRVRGAEEPYWTVTGLGSQGALAAPVMTPFLTEHANSSNQRTMAADEPLRTICAQVKGGHFSAVAPVIAPLRGTSEQ
HLQGDDTREPLSTVSAGGTHHALAGAVLAAAIVTNTTGHPGATADTPLATITTGGHHAMAAMHITKFNTGSVGSGMDEPL
RTVTAGGTPSRPSTGIQMGMVAAMLEQANGGFYDGDGRPVGAPASTITSSGAQQRLVTAYLVKYYSEGGQDSACGAPMHT
VPTKARMGLVQTVQVPADCLAPEHRARARQCAELLHTHLPEQFPDPAALVLMHHAGQWWVLVDITLRMLKPVELFRAQGF
PEDYVIHEIPDPALLFAGGKQAAHPLEVQRIPLTATAQVRMCGNSVSPPQAEALVRANFGHETAWMAVAA

Sequences:

>Translated_710_residues
MKRDAFTLPLAFPGELIIDNFAGGGGTSTGLEAAFGRPVDIAINHDPEALAMHAINHPHTQHLCESVWEVDPIAVTGNQP
VGLVWLSPDCKHFSKAKGGTPVAKHIRGLAWVGMRWVALCKPRVLMLENVEEFQTWGPLLVGADGTARPDPARKGKTFQS
FVRQLRAHGYAVDWRELRACDNGAPTIRKRLFLIARRDGLPIQWPEQTHAAPTDRRVLAGKLAPYRTAADCIDFSLEAAS
IFDRQRPLATNTQRRVAKGLFRHVLTSASPFIVGVGGRMGQSPARSVHAPAQTITAKADSCIAQPVLTPYMVNTRNGERA
GQQPRVRGAEEPYWTVTGLGSQGALAAPVMTPFLTEHANSSNQRTMAADEPLRTICAQVKGGHFSAVAPVIAPLRGTSEQ
HLQGDDTREPLSTVSAGGTHHALAGAVLAAAIVTNTTGHPGATADTPLATITTGGHHAMAAMHITKFNTGSVGSGMDEPL
RTVTAGGTPSRPSTGIQMGMVAAMLEQANGGFYDGDGRPVGAPASTITSSGAQQRLVTAYLVKYYSEGGQDSACGAPMHT
VPTKARMGLVQTVQVPADCLAPEHRARARQCAELLHTHLPEQFPDPAALVLMHHAGQWWVLVDITLRMLKPVELFRAQGF
PEDYVIHEIPDPALLFAGGKQAAHPLEVQRIPLTATAQVRMCGNSVSPPQAEALVRANFGHETAWMAVAA
>Mature_710_residues
MKRDAFTLPLAFPGELIIDNFAGGGGTSTGLEAAFGRPVDIAINHDPEALAMHAINHPHTQHLCESVWEVDPIAVTGNQP
VGLVWLSPDCKHFSKAKGGTPVAKHIRGLAWVGMRWVALCKPRVLMLENVEEFQTWGPLLVGADGTARPDPARKGKTFQS
FVRQLRAHGYAVDWRELRACDNGAPTIRKRLFLIARRDGLPIQWPEQTHAAPTDRRVLAGKLAPYRTAADCIDFSLEAAS
IFDRQRPLATNTQRRVAKGLFRHVLTSASPFIVGVGGRMGQSPARSVHAPAQTITAKADSCIAQPVLTPYMVNTRNGERA
GQQPRVRGAEEPYWTVTGLGSQGALAAPVMTPFLTEHANSSNQRTMAADEPLRTICAQVKGGHFSAVAPVIAPLRGTSEQ
HLQGDDTREPLSTVSAGGTHHALAGAVLAAAIVTNTTGHPGATADTPLATITTGGHHAMAAMHITKFNTGSVGSGMDEPL
RTVTAGGTPSRPSTGIQMGMVAAMLEQANGGFYDGDGRPVGAPASTITSSGAQQRLVTAYLVKYYSEGGQDSACGAPMHT
VPTKARMGLVQTVQVPADCLAPEHRARARQCAELLHTHLPEQFPDPAALVLMHHAGQWWVLVDITLRMLKPVELFRAQGF
PEDYVIHEIPDPALLFAGGKQAAHPLEVQRIPLTATAQVRMCGNSVSPPQAEALVRANFGHETAWMAVAA

Specific function: This methylase recognizes the double-stranded sequence CYCGRG, causes specific methylation on C-1 on both strands, and protects the DNA from cleavage by the AquI endonuclease [H]

COG id: COG0270

COG function: function code L; Site-specific DNA methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the C5-methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018117
- InterPro:   IPR001525 [H]

Pfam domain/function: PF00145 DNA_methylase [H]

EC number: =2.1.1.37 [H]

Molecular weight: Translated: 75806; Mature: 75806

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRDAFTLPLAFPGELIIDNFAGGGGTSTGLEAAFGRPVDIAINHDPEALAMHAINHPHT
CCCCCEEEEECCCCCEEEECCCCCCCCCCCCHHHCCCCEEEEECCCCHHHHHHHCCCCHH
QHLCESVWEVDPIAVTGNQPVGLVWLSPDCKHFSKAKGGTPVAKHIRGLAWVGMRWVALC
HHHHHHHHCCCCEEEECCCCEEEEEECCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHC
KPRVLMLENVEEFQTWGPLLVGADGTARPDPARKGKTFQSFVRQLRAHGYAVDWRELRAC
CCCEEECCCHHHHHHCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCEECHHHHHHC
DNGAPTIRKRLFLIARRDGLPIQWPEQTHAAPTDRRVLAGKLAPYRTAADCIDFSLEAAS
CCCCHHHHHHEEEEECCCCCCCCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHCCHHHH
IFDRQRPLATNTQRRVAKGLFRHVLTSASPFIVGVGGRMGQSPARSVHAPAQTITAKADS
HHHCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHCCCHHHHHHHHHH
CIAQPVLTPYMVNTRNGERAGQQPRVRGAEEPYWTVTGLGSQGALAAPVMTPFLTEHANS
HHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEECHHHHHHHHHHCCC
SNQRTMAADEPLRTICAQVKGGHFSAVAPVIAPLRGTSEQHLQGDDTREPLSTVSAGGTH
CCCCEECCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHCCCCCCCCHHHHHHCCCCH
HALAGAVLAAAIVTNTTGHPGATADTPLATITTGGHHAMAAMHITKFNTGSVGSGMDEPL
HHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCEEEEEEEEECCCCCCCCCCCHHH
RTVTAGGTPSRPSTGIQMGMVAAMLEQANGGFYDGDGRPVGAPASTITSSGAQQRLVTAY
HHEECCCCCCCCCCCHHHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHCCCHHHHHHHHH
LVKYYSEGGQDSACGAPMHTVPTKARMGLVQTVQVPADCLAPEHRARARQCAELLHTHLP
HHHHHHCCCCCCCCCCCCCCCCCHHHHCHHHEEECCHHHCCCHHHHHHHHHHHHHHHHCC
EQFPDPAALVLMHHAGQWWVLVDITLRMLKPVELFRAQGFPEDYVIHEIPDPALLFAGGK
HHCCCHHHEEEEECCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEEECCC
QAAHPLEVQRIPLTATAQVRMCGNSVSPPQAEALVRANFGHETAWMAVAA
CCCCCCEEEECCCCCEEEEEECCCCCCCCHHHHHEEECCCCCEEEEEEEC
>Mature Secondary Structure
MKRDAFTLPLAFPGELIIDNFAGGGGTSTGLEAAFGRPVDIAINHDPEALAMHAINHPHT
CCCCCEEEEECCCCCEEEECCCCCCCCCCCCHHHCCCCEEEEECCCCHHHHHHHCCCCHH
QHLCESVWEVDPIAVTGNQPVGLVWLSPDCKHFSKAKGGTPVAKHIRGLAWVGMRWVALC
HHHHHHHHCCCCEEEECCCCEEEEEECCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHC
KPRVLMLENVEEFQTWGPLLVGADGTARPDPARKGKTFQSFVRQLRAHGYAVDWRELRAC
CCCEEECCCHHHHHHCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCEECHHHHHHC
DNGAPTIRKRLFLIARRDGLPIQWPEQTHAAPTDRRVLAGKLAPYRTAADCIDFSLEAAS
CCCCHHHHHHEEEEECCCCCCCCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHCCHHHH
IFDRQRPLATNTQRRVAKGLFRHVLTSASPFIVGVGGRMGQSPARSVHAPAQTITAKADS
HHHCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHCCCHHHHHHHHHH
CIAQPVLTPYMVNTRNGERAGQQPRVRGAEEPYWTVTGLGSQGALAAPVMTPFLTEHANS
HHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEECHHHHHHHHHHCCC
SNQRTMAADEPLRTICAQVKGGHFSAVAPVIAPLRGTSEQHLQGDDTREPLSTVSAGGTH
CCCCEECCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHCCCCCCCCHHHHHHCCCCH
HALAGAVLAAAIVTNTTGHPGATADTPLATITTGGHHAMAAMHITKFNTGSVGSGMDEPL
HHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCEEEEEEEEECCCCCCCCCCCHHH
RTVTAGGTPSRPSTGIQMGMVAAMLEQANGGFYDGDGRPVGAPASTITSSGAQQRLVTAY
HHEECCCCCCCCCCCHHHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHCCCHHHHHHHHH
LVKYYSEGGQDSACGAPMHTVPTKARMGLVQTVQVPADCLAPEHRARARQCAELLHTHLP
HHHHHHCCCCCCCCCCCCCCCCCHHHHCHHHEEECCHHHCCCHHHHHHHHHHHHHHHHCC
EQFPDPAALVLMHHAGQWWVLVDITLRMLKPVELFRAQGFPEDYVIHEIPDPALLFAGGK
HHCCCHHHEEEEECCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEEECCC
QAAHPLEVQRIPLTATAQVRMCGNSVSPPQAEALVRANFGHETAWMAVAA
CCCCCCEEEECCCCCEEEEEECCCCCCCCHHHHHEEECCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2104605 [H]