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The map label for this gene is efp

Identifier: 120610331

GI number: 120610331

Start: 1807265

End: 1807819

Strand: Reverse

Name: efp

Synonym: Aave_1648

Alternate gene names: 120610331

Gene position: 1807819-1807265 (Counterclockwise)

Preceding gene: 120610332

Following gene: 120610330

Centisome position: 33.77

GC content: 61.26

Gene sequence:

>555_bases
ATGAAAATCGCTCAAGAAATCCGCGCCGGCAACGTGATCATGCACGGCAAGGACCCGATGATCGTCCTCAAGACCGAATA
CGCACGCGGCGGCCGCGGCGCCGCCACCGTGCGCATGAAGCTCAAGGCCCTGCTGAACAACATGGGCACCGAAGTGGTGT
TCAAGGCCGACGACAAGATCGACAACGTGATCCTGGACAAGAAGGAGTGCACCTACTCCTACTTCGCCGATCCGATGTAC
GTCTGCATGGACGCCGAGTACAACCAGTACGAAGTCGAAGCCGAGAACATGGGCGACGCGCTGAACTACCTGGAAGACGG
CATGGCCGTCGAAGTGGTGTTCTACGACGGCAAGGCCATCTCGGTCGAACTGCCCACCAGCGTCGAGCGCGAAATCACCT
GGACCGAGCCCGCCGTCAAGGGCGACACGTCCGGCAAGGTGCTCAAGCCCGCCAAGATCGCCACCGGCTTCGAAGTGGCC
GTGCCCCTGTTCGTGAACCAGGGCGACAGGATCGAAATCGACACCCGCACGGGCGAATACCGCAAGCGCGTCTGA

Upstream 100 bases:

>100_bases
GCGGAACCTGCCCGGCGCCCTTGCCGCACCGCCGCGCTCGCAGCCGGCCTTCGGCGGGCGCTCCGGTGCGTTGAGCGGCC
CCAACCCAGGCAGACCTGCT

Downstream 100 bases:

>100_bases
GCGCCGCTCCGCCTCCCGGCGGAGAGCGAACCGTCACGCGACGACAAGGGCACGGGCCGTCAGGCCGGTGCCCTTTTTGC
TTGGGTGCCGGCCCGGCCCT

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MKIAQEIRAGNVIMHGKDPMIVLKTEYARGGRGAATVRMKLKALLNNMGTEVVFKADDKIDNVILDKKECTYSYFADPMY
VCMDAEYNQYEVEAENMGDALNYLEDGMAVEVVFYDGKAISVELPTSVEREITWTEPAVKGDTSGKVLKPAKIATGFEVA
VPLFVNQGDRIEIDTRTGEYRKRV

Sequences:

>Translated_184_residues
MKIAQEIRAGNVIMHGKDPMIVLKTEYARGGRGAATVRMKLKALLNNMGTEVVFKADDKIDNVILDKKECTYSYFADPMY
VCMDAEYNQYEVEAENMGDALNYLEDGMAVEVVFYDGKAISVELPTSVEREITWTEPAVKGDTSGKVLKPAKIATGFEVA
VPLFVNQGDRIEIDTRTGEYRKRV
>Mature_184_residues
MKIAQEIRAGNVIMHGKDPMIVLKTEYARGGRGAATVRMKLKALLNNMGTEVVFKADDKIDNVILDKKECTYSYFADPMY
VCMDAEYNQYEVEAENMGDALNYLEDGMAVEVVFYDGKAISVELPTSVEREITWTEPAVKGDTSGKVLKPAKIATGFEVA
VPLFVNQGDRIEIDTRTGEYRKRV

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=182, Percent_Identity=37.9120879120879, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI87082061, Length=188, Percent_Identity=31.3829787234043, Blast_Score=89, Evalue=1e-19,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_ACIAC (A1TMP7)

Other databases:

- EMBL:   CP000512
- RefSeq:   YP_970009.1
- ProteinModelPortal:   A1TMP7
- SMR:   A1TMP7
- STRING:   A1TMP7
- GeneID:   4668844
- GenomeReviews:   CP000512_GR
- KEGG:   aav:Aave_1648
- eggNOG:   COG0231
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- PhylomeDB:   A1TMP7
- ProtClustDB:   PRK00529
- BioCyc:   AAVE397945:AAVE_1648-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20560; Mature: 20560

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAQEIRAGNVIMHGKDPMIVLKTEYARGGRGAATVRMKLKALLNNMGTEVVFKADDKI
CCCHHHHCCCCEEEECCCCEEEEEECCCCCCCCEEEHHHHHHHHHHCCCCEEEEECCCCC
DNVILDKKECTYSYFADPMYVCMDAEYNQYEVEAENMGDALNYLEDGMAVEVVFYDGKAI
CCEEECCCCCCEEECCCEEEEEEECCCCEEEEEHHHCCHHHHHHCCCCEEEEEEECCEEE
SVELPTSVEREITWTEPAVKGDTSGKVLKPAKIATGFEVAVPLFVNQGDRIEIDTRTGEY
EEECCCCCCCEEEECCCCCCCCCCCCEECCCCCCCCEEEEEEEEECCCCEEEEECCCCCH
RKRV
HCCC
>Mature Secondary Structure
MKIAQEIRAGNVIMHGKDPMIVLKTEYARGGRGAATVRMKLKALLNNMGTEVVFKADDKI
CCCHHHHCCCCEEEECCCCEEEEEECCCCCCCCEEEHHHHHHHHHHCCCCEEEEECCCCC
DNVILDKKECTYSYFADPMYVCMDAEYNQYEVEAENMGDALNYLEDGMAVEVVFYDGKAI
CCEEECCCCCCEEECCCEEEEEEECCCCEEEEEHHHCCHHHHHHCCCCEEEEEEECCEEE
SVELPTSVEREITWTEPAVKGDTSGKVLKPAKIATGFEVAVPLFVNQGDRIEIDTRTGEY
EEECCCCCCCEEEECCCCCCCCCCCCEECCCCCCCCEEEEEEEEECCCCEEEEECCCCCH
RKRV
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA