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The map label for this gene is ompR [H]

Identifier: 120610269

GI number: 120610269

Start: 1750185

End: 1750916

Strand: Reverse

Name: ompR [H]

Synonym: Aave_1584

Alternate gene names: 120610269

Gene position: 1750916-1750185 (Counterclockwise)

Preceding gene: 120610271

Following gene: 120610268

Centisome position: 32.71

GC content: 68.72

Gene sequence:

>732_bases
ATGGCCTCTACAACCAACCGTACCGACAAGATCCTCGTGGTGGACGACGACGCGCGCATCCGTGATTTGCTGCGCCGCTA
TCTGACCCAGGAAGGCTTCGAAGTCATGGTGGCGGAAGACGGCAAGGCGCTCAACCGCATCCTGCTGCGCGAGACGGTCG
AACTGATCGTTCTGGATCTCATGATGCCCGGCGAGGACGGGCTCTCCATCTGCCGCCGCCTGCGCGCGGCCAACGACCGC
ACCCCGATCATCATGCTCACCGCCAAGGGCGAGGACGTGGACCGCATCGTCGGCCTGGAGGTGGGTGCGGACGACTACCT
GGGCAAGCCCTTCAATCCCCGCGAACTGCTGGCGCGCATCCATGCCGTGCTGCGCCGCCGCCCGCCGCAGGAGGCCCCCG
GCGCCCCGTCGGGCGACAACGAGGTCGTGACCTTCGGCCCCTTCACCTTCGACCTGGGCACCCGCGCCCTGCAGAAGAAC
GGCGAGGAGCTGCCCCTCACCACCGGCGAATTCGCCATGCTCAAGGCCCTGGTGCGCCACCCGCGCCAGCCGCTGTCGCG
CGAAAAACTGGCCCTGCTGGCCCGCGGCCGCGAGTTCGAGCCCTTCGACCGCAGCCTGGACGTGCAGGTCTCGCGCCTGC
GCAAGCTGGTCGAGGTGGACGCCGCCGCCCCCCGCTACATCCAGACCGTCTGGGGCGTGGGCTACGTGTTCGTGCCGGAT
GGAGCGAGCTGA

Upstream 100 bases:

>100_bases
CAAAATTTGTAACACTTGGTCAGACCCGCCGGAAAAACGCGAACTTCGGGCGGCAAGGTGGTCAGAATCGGCTCTGTTAC
AAATAGGACCCAGGAAACTC

Downstream 100 bases:

>100_bases
TCCACGGCCGACAACCCCGCGCGCGGGCACCGGGGCGGCACCCTGTGCAGCCCCGGTGCCCGCAGCCCTTCCACGGCCTG
CAGCGGCCCGGCTCTTCTCC

Product: osmolarity response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MASTTNRTDKILVVDDDARIRDLLRRYLTQEGFEVMVAEDGKALNRILLRETVELIVLDLMMPGEDGLSICRRLRAANDR
TPIIMLTAKGEDVDRIVGLEVGADDYLGKPFNPRELLARIHAVLRRRPPQEAPGAPSGDNEVVTFGPFTFDLGTRALQKN
GEELPLTTGEFAMLKALVRHPRQPLSREKLALLARGREFEPFDRSLDVQVSRLRKLVEVDAAAPRYIQTVWGVGYVFVPD
GAS

Sequences:

>Translated_243_residues
MASTTNRTDKILVVDDDARIRDLLRRYLTQEGFEVMVAEDGKALNRILLRETVELIVLDLMMPGEDGLSICRRLRAANDR
TPIIMLTAKGEDVDRIVGLEVGADDYLGKPFNPRELLARIHAVLRRRPPQEAPGAPSGDNEVVTFGPFTFDLGTRALQKN
GEELPLTTGEFAMLKALVRHPRQPLSREKLALLARGREFEPFDRSLDVQVSRLRKLVEVDAAAPRYIQTVWGVGYVFVPD
GAS
>Mature_242_residues
ASTTNRTDKILVVDDDARIRDLLRRYLTQEGFEVMVAEDGKALNRILLRETVELIVLDLMMPGEDGLSICRRLRAANDRT
PIIMLTAKGEDVDRIVGLEVGADDYLGKPFNPRELLARIHAVLRRRPPQEAPGAPSGDNEVVTFGPFTFDLGTRALQKNG
EELPLTTGEFAMLKALVRHPRQPLSREKLALLARGREFEPFDRSLDVQVSRLRKLVEVDAAAPRYIQTVWGVGYVFVPDG
AS

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=234, Percent_Identity=65.3846153846154, Blast_Score=316, Evalue=9e-88,
Organism=Escherichia coli, GI2367329, Length=235, Percent_Identity=39.1489361702128, Blast_Score=151, Evalue=3e-38,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=34.8936170212766, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1788394, Length=235, Percent_Identity=36.1702127659575, Blast_Score=144, Evalue=4e-36,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=38.2608695652174, Blast_Score=143, Evalue=9e-36,
Organism=Escherichia coli, GI1786784, Length=233, Percent_Identity=38.1974248927039, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=35.3448275862069, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI145693140, Length=238, Percent_Identity=36.9747899159664, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1787375, Length=233, Percent_Identity=35.6223175965665, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1790552, Length=231, Percent_Identity=36.3636363636364, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1790860, Length=227, Percent_Identity=33.0396475770925, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1786911, Length=232, Percent_Identity=35.7758620689655, Blast_Score=121, Evalue=3e-29,
Organism=Escherichia coli, GI87082012, Length=229, Percent_Identity=33.1877729257642, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1789402, Length=228, Percent_Identity=33.7719298245614, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1790299, Length=123, Percent_Identity=30.8943089430894, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=32.4074074074074, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788905, Length=125, Percent_Identity=32.8, Blast_Score=64, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6322000, Length=155, Percent_Identity=27.0967741935484, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27175; Mature: 27044

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASTTNRTDKILVVDDDARIRDLLRRYLTQEGFEVMVAEDGKALNRILLRETVELIVLDL
CCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHH
MMPGEDGLSICRRLRAANDRTPIIMLTAKGEDVDRIVGLEVGADDYLGKPFNPRELLARI
HCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCHHEEEEEECCHHHCCCCCCHHHHHHHH
HAVLRRRPPQEAPGAPSGDNEVVTFGPFTFDLGTRALQKNGEELPLTTGEFAMLKALVRH
HHHHHCCCCCCCCCCCCCCCCEEEECCEEHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHC
PRQPLSREKLALLARGREFEPFDRSLDVQVSRLRKLVEVDAAAPRYIQTVWGVGYVFVPD
CCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEECC
GAS
CCC
>Mature Secondary Structure 
ASTTNRTDKILVVDDDARIRDLLRRYLTQEGFEVMVAEDGKALNRILLRETVELIVLDL
CCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHH
MMPGEDGLSICRRLRAANDRTPIIMLTAKGEDVDRIVGLEVGADDYLGKPFNPRELLARI
HCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCHHEEEEEECCHHHCCCCCCHHHHHHHH
HAVLRRRPPQEAPGAPSGDNEVVTFGPFTFDLGTRALQKNGEELPLTTGEFAMLKALVRH
HHHHHCCCCCCCCCCCCCCCCEEEECCEEHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHC
PRQPLSREKLALLARGREFEPFDRSLDVQVSRLRKLVEVDAAAPRYIQTVWGVGYVFVPD
CCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEECC
GAS
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]