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The map label for this gene is baeS [H]

Identifier: 120610180

GI number: 120610180

Start: 1657097

End: 1658680

Strand: Reverse

Name: baeS [H]

Synonym: Aave_1494

Alternate gene names: 120610180

Gene position: 1658680-1657097 (Counterclockwise)

Preceding gene: 120610181

Following gene: 120610179

Centisome position: 30.99

GC content: 73.42

Gene sequence:

>1584_bases
ATGCCACGACTGACCCTGCAGAGCAAAGCCTTCCTCGCGCTCAGCGTCCTGCTGGCCGTGTTGCTGGCACTGTTCGTGGG
GTTCTCCCGCCTGGGACTGCAGCGGGGGCTGGGCCCCTACATCGCAGAGATCGAACTCGGCCGGCTGGACTGGCTCGCAG
GGCGGCTGGAACGCGTCTATGTGCTGCACGGCGGCTGGCAGACCCTGCGCACGCAGCCCGAGCTGTGGCGCCAGATGCAC
AAGCCCGGCGTTGCCCTGCCCCGGGCGACCTTCGGGCCCACCCGACCCGCCCTGCCACCCGGCGGCGCGGCGCCACAGGG
CGCACGGAACGCACCCGCGACGTGCGACGTGGATGCCTATGCGTTCGGCGATGGCACCCCCCCGGCCTCCGCCGGGACGC
CGTCCGGTAAAGCCCCCTCCTCTCCCGATCCCAACCAGCACGCGCTGTCGGTCCGCCTGGGGCTGATCGACGGCGACCGC
CAGCTGGTCGCCGGCGTCCAGCCGGTGCAGGGCACGGCCCGGCGCGTGCTGCGCGGCCCCCGCGGCGAAGCCATCGGCCA
GCTCGTGCTGCTGCCGCCACTGAACGTGGAAACCGAGGCGGACCAGGCCTTCCTGCGCCAGCAACTGGTGTTCGTCGCCT
GGACGGGCGCCGCGGGCCTGATCCTCGCGCTCTGGCTGTCCTGGTGGCTGGCCCGGCGCTGGCTGGCCCCCATCGGCGCG
CTGGTCCACGCCGCGCGCCGGGTGGCCGGCGGACGGCTGGACACGCGCGTGCCGGTGCAGGGCGACGACGAACTGGCCCG
GCTCGCCTCCACGTTCAACGACATGGCGGAGCAGCTCGCGAACATGGAAGCCTCGCGCCGCCAGTGGATCGGCGACGTGG
CGCACGAACTCCGCACGCCCCTGGCGGCCATGCGCGCGGAAATCGAGGCCGTGCAGGATGGCGTGCGCACCTTCGACGAC
AGGACGGCGCTGCGCCTGCACCGGCAGGTGATGCGGCTGATCCAGCTGGTGGGAGACCTGCGCGCGAGCCTCGACGCCGC
GGGCGACGCCACGCCCTCGGCGCCGGAGCCCGTGCAGCCGCTGCCCCTGCTGTCGGAGGCCGTCGCCTCGATGCAGGCGC
GCTTCGACAACGCCGGCATCGCCCTGGACATGTCCGCCGTGGACGCCTGCGCGGGCAGCCACCCGCCCCCGGTGGTGCGG
GGCGACCCGGCGCAACTGCACCGCGTGTACCTCAACCTGCTGGAAAACAGCCTGCGCTACACCGAAACGGGCGGCAGGCT
CTGCATCGCCGCGCACACCGAACGCAAGGCGGGCGATGGTGCCTGGCTCGTGCTGCAATGGGACGATACGGCCCCCGGCG
TCCCCGCACCGGAGCTGCCGCGTGTGTTCGACCGGCTCTACCGTGCCGAAGCCTCCCGCACCCGCGCCGCGGGCGACACC
GGCGGCTCCGGCCTGGGGCTGGCCATCTGCCGGGCCATCGTGCAGGCGCACGGCGGACGGATCACGGCCGAGGCCTCGCC
GCTGGGCGGCCTGCGCATTCTTCTCACCCTGCCCTTGCTGGAGACCCCCATCCATGACCGATGA

Upstream 100 bases:

>100_bases
TGATTCGGTGGGCACAGTCGAACCCATCCATACTCGAGGAACACGGACGCCCGGCCGGCCCCGCGCCCGCCGGCACCCCT
GGACCACGCAGCCCGAACAG

Downstream 100 bases:

>100_bases
CCCCCAACGCATTCTGGTGGTGGAGGACGAGCCCGACATCGCGGACGTCGTTCTGGACTACCTGCGGCATTCCGGCTTCG
AGGCCGAACACCTGGCCGAG

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 527; Mature: 526

Protein sequence:

>527_residues
MPRLTLQSKAFLALSVLLAVLLALFVGFSRLGLQRGLGPYIAEIELGRLDWLAGRLERVYVLHGGWQTLRTQPELWRQMH
KPGVALPRATFGPTRPALPPGGAAPQGARNAPATCDVDAYAFGDGTPPASAGTPSGKAPSSPDPNQHALSVRLGLIDGDR
QLVAGVQPVQGTARRVLRGPRGEAIGQLVLLPPLNVETEADQAFLRQQLVFVAWTGAAGLILALWLSWWLARRWLAPIGA
LVHAARRVAGGRLDTRVPVQGDDELARLASTFNDMAEQLANMEASRRQWIGDVAHELRTPLAAMRAEIEAVQDGVRTFDD
RTALRLHRQVMRLIQLVGDLRASLDAAGDATPSAPEPVQPLPLLSEAVASMQARFDNAGIALDMSAVDACAGSHPPPVVR
GDPAQLHRVYLNLLENSLRYTETGGRLCIAAHTERKAGDGAWLVLQWDDTAPGVPAPELPRVFDRLYRAEASRTRAAGDT
GGSGLGLAICRAIVQAHGGRITAEASPLGGLRILLTLPLLETPIHDR

Sequences:

>Translated_527_residues
MPRLTLQSKAFLALSVLLAVLLALFVGFSRLGLQRGLGPYIAEIELGRLDWLAGRLERVYVLHGGWQTLRTQPELWRQMH
KPGVALPRATFGPTRPALPPGGAAPQGARNAPATCDVDAYAFGDGTPPASAGTPSGKAPSSPDPNQHALSVRLGLIDGDR
QLVAGVQPVQGTARRVLRGPRGEAIGQLVLLPPLNVETEADQAFLRQQLVFVAWTGAAGLILALWLSWWLARRWLAPIGA
LVHAARRVAGGRLDTRVPVQGDDELARLASTFNDMAEQLANMEASRRQWIGDVAHELRTPLAAMRAEIEAVQDGVRTFDD
RTALRLHRQVMRLIQLVGDLRASLDAAGDATPSAPEPVQPLPLLSEAVASMQARFDNAGIALDMSAVDACAGSHPPPVVR
GDPAQLHRVYLNLLENSLRYTETGGRLCIAAHTERKAGDGAWLVLQWDDTAPGVPAPELPRVFDRLYRAEASRTRAAGDT
GGSGLGLAICRAIVQAHGGRITAEASPLGGLRILLTLPLLETPIHDR
>Mature_526_residues
PRLTLQSKAFLALSVLLAVLLALFVGFSRLGLQRGLGPYIAEIELGRLDWLAGRLERVYVLHGGWQTLRTQPELWRQMHK
PGVALPRATFGPTRPALPPGGAAPQGARNAPATCDVDAYAFGDGTPPASAGTPSGKAPSSPDPNQHALSVRLGLIDGDRQ
LVAGVQPVQGTARRVLRGPRGEAIGQLVLLPPLNVETEADQAFLRQQLVFVAWTGAAGLILALWLSWWLARRWLAPIGAL
VHAARRVAGGRLDTRVPVQGDDELARLASTFNDMAEQLANMEASRRQWIGDVAHELRTPLAAMRAEIEAVQDGVRTFDDR
TALRLHRQVMRLIQLVGDLRASLDAAGDATPSAPEPVQPLPLLSEAVASMQARFDNAGIALDMSAVDACAGSHPPPVVRG
DPAQLHRVYLNLLENSLRYTETGGRLCIAAHTERKAGDGAWLVLQWDDTAPGVPAPELPRVFDRLYRAEASRTRAAGDTG
GSGLGLAICRAIVQAHGGRITAEASPLGGLRILLTLPLLETPIHDR

Specific function: Member of the two-component regulatory system BaeS/BaeR. May activate BaeR by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=517, Percent_Identity=33.4622823984526, Blast_Score=221, Evalue=6e-59,
Organism=Escherichia coli, GI1786783, Length=315, Percent_Identity=30.4761904761905, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI1790346, Length=288, Percent_Identity=29.8611111111111, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1787894, Length=319, Percent_Identity=29.7805642633229, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI145693157, Length=260, Percent_Identity=25.7692307692308, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1789149, Length=387, Percent_Identity=25.3229974160207, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI87081816, Length=350, Percent_Identity=25.7142857142857, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1786912, Length=271, Percent_Identity=28.4132841328413, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI87082128, Length=302, Percent_Identity=25.4966887417219, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1787374, Length=304, Percent_Identity=25.9868421052632, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1790861, Length=300, Percent_Identity=26.3333333333333, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790551, Length=293, Percent_Identity=26.2798634812287, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788713, Length=243, Percent_Identity=26.3374485596708, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 56489; Mature: 56357

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRLTLQSKAFLALSVLLAVLLALFVGFSRLGLQRGLGPYIAEIELGRLDWLAGRLERVY
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEECCHHHHHHHHHCEEE
VLHGGWQTLRTQPELWRQMHKPGVALPRATFGPTRPALPPGGAAPQGARNAPATCDVDAY
EEECCHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCE
AFGDGTPPASAGTPSGKAPSSPDPNQHALSVRLGLIDGDRQLVAGVQPVQGTARRVLRGP
ECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCHHHHHCCCCCHHHHHHHHCCC
RGEAIGQLVLLPPLNVETEADQAFLRQQLVFVAWTGAAGLILALWLSWWLARRWLAPIGA
CCHHHCCEEEECCCCCCCCHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
LVHAARRVAGGRLDTRVPVQGDDELARLASTFNDMAEQLANMEASRRQWIGDVAHELRTP
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LAAMRAEIEAVQDGVRTFDDRTALRLHRQVMRLIQLVGDLRASLDAAGDATPSAPEPVQP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
LPLLSEAVASMQARFDNAGIALDMSAVDACAGSHPPPVVRGDPAQLHRVYLNLLENSLRY
CHHHHHHHHHHHHHHCCCCEEEEHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHE
TETGGRLCIAAHTERKAGDGAWLVLQWDDTAPGVPAPELPRVFDRLYRAEASRTRAAGDT
ECCCCEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
GGSGLGLAICRAIVQAHGGRITAEASPLGGLRILLTLPLLETPIHDR
CCCHHHHHHHHHHHHHCCCEEEECCCCCCCEEHEEEHHHHCCCCCCC
>Mature Secondary Structure 
PRLTLQSKAFLALSVLLAVLLALFVGFSRLGLQRGLGPYIAEIELGRLDWLAGRLERVY
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEECCHHHHHHHHHCEEE
VLHGGWQTLRTQPELWRQMHKPGVALPRATFGPTRPALPPGGAAPQGARNAPATCDVDAY
EEECCHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCE
AFGDGTPPASAGTPSGKAPSSPDPNQHALSVRLGLIDGDRQLVAGVQPVQGTARRVLRGP
ECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCHHHHHCCCCCHHHHHHHHCCC
RGEAIGQLVLLPPLNVETEADQAFLRQQLVFVAWTGAAGLILALWLSWWLARRWLAPIGA
CCHHHCCEEEECCCCCCCCHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
LVHAARRVAGGRLDTRVPVQGDDELARLASTFNDMAEQLANMEASRRQWIGDVAHELRTP
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LAAMRAEIEAVQDGVRTFDDRTALRLHRQVMRLIQLVGDLRASLDAAGDATPSAPEPVQP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
LPLLSEAVASMQARFDNAGIALDMSAVDACAGSHPPPVVRGDPAQLHRVYLNLLENSLRY
CHHHHHHHHHHHHHHCCCCEEEEHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHE
TETGGRLCIAAHTERKAGDGAWLVLQWDDTAPGVPAPELPRVFDRLYRAEASRTRAAGDT
ECCCCEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
GGSGLGLAICRAIVQAHGGRITAEASPLGGLRILLTLPLLETPIHDR
CCCHHHHHHHHHHHHHCCCEEEECCCCCCCEEHEEEHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 9097040; 9278503 [H]