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The map label for this gene is mdtA [H]

Identifier: 120610149

GI number: 120610149

Start: 1614190

End: 1615446

Strand: Reverse

Name: mdtA [H]

Synonym: Aave_1462

Alternate gene names: 120610149

Gene position: 1615446-1614190 (Counterclockwise)

Preceding gene: 120610151

Following gene: 120610148

Centisome position: 30.18

GC content: 74.14

Gene sequence:

>1257_bases
ATGCCGCTTTCCGCGCAGCCCCGGACTTCCAGGCGCACCCGCCCCCTCCAGCCCCTCCGTGGGGCTTTTTCGTGGCAGCC
CGTGCTCAGCCGGCAGTGGGCCATGATCGCCTCCGTCGCGGCGGTCCTGGCACTCGGGGCCTGTTCCCGAAAGGAGCCGC
CGCCGGAGCCCGTGCGCTCGGTCAAGCTGCTCACCGTCGGCACGTCGTCGCTCCACACGCATGCGGAATATGCCGGCGAA
GTGCGCGCCCGCATCGAATCGCGCCTGGGCTTCCGCGTGGCGGGCAAGATCGTCCAGCGGCAGGCGGAACTCGGACAGCG
CGTGCAGGCCGGCCAGGTGCTGGCGCAGATCGATCCGCGCGACTACCAGCTGTCCGCGGACGCGGCGCGTGCCCAGGTGG
CATCGGCGCAGACCCAGCGGGATCTGGCGGCGGCGGATTACCAGCGCTTTTCCGCGCTCAAGGCGCAGAACTTCATCAGC
GGCGCCGAGCTCGACCGGCGCTCGGCCACGCTGAAGGCCGCCGAAGCCTCGCTCGAACAGGCCCGGGCCCAGGCGGCCTC
GCAGAGCAACCAGACGCAGTACACGCGGCTCGTGGCCGATGCCGCCGGCGTGGTCACCGGCATCGACGCCGAGCCCGGCC
AGGTGGTCGCGGCCGGCACGCCGGTCGTGCGGATCGCCCAGGACGGGCCGCGCGACGTGGTGTTCTCGGTGCCCGAAGAC
CGGCTCGCCCGCGTGCGCCCTGGGCAGGCCGTGACCGTCCGCACTTGGTCGGGAGGCGGCGCGCTGCCGGGCCGGGTGCG
CGAAGTGGCCGCGAGTGCCGATCCGGTCACGCGCACCTTCCTGGCCAAGGTCGCCATCGAATCCGACACGCCCCCGCCCC
TGGGCGCCACCGCCTACGTGACGCCCGACGGGGCCGCGCAGCAAGGGCCGCAGGCCATCAAGCTGCCGACGAGCGCGCTG
CGCCAGGAAGGCGCGCAGACCGCCGTCTGGGTCTACGAGCCAGCCAGCGGCACGGTGCGCTCGCAGGCCGTGCAGATCGC
GAGCGCCGACGGCAACGAGGTGGTGGTGGGCAGCGGCCTTGCGCCGGGCATGCAGGTGGTGGCTGCCGGCGTGCACGTGC
TCTCTCCGGGGCAGAAGGTGCTGGTCTACCAGCCGCGCGCGTCCCGTGGCGGCGAGGCTCCGGCCACCACGCCCGTTTCC
GCACCGGTTCCGGCCGCATCCGGCGCCGCGCCCGCGGCCTCCGCCACCGCACGCTGA

Upstream 100 bases:

>100_bases
AATGTGGCGTGGTCACCCGGCGATTGTCGCTTGACGCTGCCGAGGCTTTCACCTAGATTACTAACCAGTCAGTCATTAAC
CGCCCTCCTCGGGAACCACC

Downstream 100 bases:

>100_bases
GGCCCCCATGGAAAACGCGACGCAGCAGCCGCCCACCGGCGGATTCAACCTGTCCAAATGGGCGCTGGACCACCCCGCCC
TCACGCGCTACCTCATGGTG

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 418; Mature: 417

Protein sequence:

>418_residues
MPLSAQPRTSRRTRPLQPLRGAFSWQPVLSRQWAMIASVAAVLALGACSRKEPPPEPVRSVKLLTVGTSSLHTHAEYAGE
VRARIESRLGFRVAGKIVQRQAELGQRVQAGQVLAQIDPRDYQLSADAARAQVASAQTQRDLAAADYQRFSALKAQNFIS
GAELDRRSATLKAAEASLEQARAQAASQSNQTQYTRLVADAAGVVTGIDAEPGQVVAAGTPVVRIAQDGPRDVVFSVPED
RLARVRPGQAVTVRTWSGGGALPGRVREVAASADPVTRTFLAKVAIESDTPPPLGATAYVTPDGAAQQGPQAIKLPTSAL
RQEGAQTAVWVYEPASGTVRSQAVQIASADGNEVVVGSGLAPGMQVVAAGVHVLSPGQKVLVYQPRASRGGEAPATTPVS
APVPAASGAAPAASATAR

Sequences:

>Translated_418_residues
MPLSAQPRTSRRTRPLQPLRGAFSWQPVLSRQWAMIASVAAVLALGACSRKEPPPEPVRSVKLLTVGTSSLHTHAEYAGE
VRARIESRLGFRVAGKIVQRQAELGQRVQAGQVLAQIDPRDYQLSADAARAQVASAQTQRDLAAADYQRFSALKAQNFIS
GAELDRRSATLKAAEASLEQARAQAASQSNQTQYTRLVADAAGVVTGIDAEPGQVVAAGTPVVRIAQDGPRDVVFSVPED
RLARVRPGQAVTVRTWSGGGALPGRVREVAASADPVTRTFLAKVAIESDTPPPLGATAYVTPDGAAQQGPQAIKLPTSAL
RQEGAQTAVWVYEPASGTVRSQAVQIASADGNEVVVGSGLAPGMQVVAAGVHVLSPGQKVLVYQPRASRGGEAPATTPVS
APVPAASGAAPAASATAR
>Mature_417_residues
PLSAQPRTSRRTRPLQPLRGAFSWQPVLSRQWAMIASVAAVLALGACSRKEPPPEPVRSVKLLTVGTSSLHTHAEYAGEV
RARIESRLGFRVAGKIVQRQAELGQRVQAGQVLAQIDPRDYQLSADAARAQVASAQTQRDLAAADYQRFSALKAQNFISG
AELDRRSATLKAAEASLEQARAQAASQSNQTQYTRLVADAAGVVTGIDAEPGQVVAAGTPVVRIAQDGPRDVVFSVPEDR
LARVRPGQAVTVRTWSGGGALPGRVREVAASADPVTRTFLAKVAIESDTPPPLGATAYVTPDGAAQQGPQAIKLPTSALR
QEGAQTAVWVYEPASGTVRSQAVQIASADGNEVVVGSGLAPGMQVVAAGVHVLSPGQKVLVYQPRASRGGEAPATTPVSA
PVPAASGAAPAASATAR

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=315, Percent_Identity=26.984126984127, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI87081951, Length=193, Percent_Identity=30.5699481865285, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 43402; Mature: 43271

Theoretical pI: Translated: 10.74; Mature: 10.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLSAQPRTSRRTRPLQPLRGAFSWQPVLSRQWAMIASVAAVLALGACSRKEPPPEPVRS
CCCCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHC
VKLLTVGTSSLHTHAEYAGEVRARIESRLGFRVAGKIVQRQAELGQRVQAGQVLAQIDPR
EEEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHEEECCC
DYQLSADAARAQVASAQTQRDLAAADYQRFSALKAQNFISGAELDRRSATLKAAEASLEQ
CEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
ARAQAASQSNQTQYTRLVADAAGVVTGIDAEPGQVVAAGTPVVRIAQDGPRDVVFSVPED
HHHHHHHCCCCHHHHHHHHHHHHHEECCCCCCCEEEECCCCEEEEECCCCCCEEEECCHH
RLARVRPGQAVTVRTWSGGGALPGRVREVAASADPVTRTFLAKVAIESDTPPPLGATAYV
HHHHCCCCCEEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCEEEEE
TPDGAAQQGPQAIKLPTSALRQEGAQTAVWVYEPASGTVRSQAVQIASADGNEVVVGSGL
CCCCCHHCCCCEEECCHHHHHHCCCCEEEEEEECCCCCHHHHEEEEECCCCCEEEEECCC
APGMQVVAAGVHVLSPGQKVLVYQPRASRGGEAPATTPVSAPVPAASGAAPAASATAR
CCHHHHHHHCHHEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PLSAQPRTSRRTRPLQPLRGAFSWQPVLSRQWAMIASVAAVLALGACSRKEPPPEPVRS
CCCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHC
VKLLTVGTSSLHTHAEYAGEVRARIESRLGFRVAGKIVQRQAELGQRVQAGQVLAQIDPR
EEEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHEEECCC
DYQLSADAARAQVASAQTQRDLAAADYQRFSALKAQNFISGAELDRRSATLKAAEASLEQ
CEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
ARAQAASQSNQTQYTRLVADAAGVVTGIDAEPGQVVAAGTPVVRIAQDGPRDVVFSVPED
HHHHHHHCCCCHHHHHHHHHHHHHEECCCCCCCEEEECCCCEEEEECCCCCCEEEECCHH
RLARVRPGQAVTVRTWSGGGALPGRVREVAASADPVTRTFLAKVAIESDTPPPLGATAYV
HHHHCCCCCEEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCEEEEE
TPDGAAQQGPQAIKLPTSALRQEGAQTAVWVYEPASGTVRSQAVQIASADGNEVVVGSGL
CCCCCHHCCCCEEECCHHHHHHCCCCEEEEEEECCCCCHHHHEEEEECCCCCEEEEECCC
APGMQVVAAGVHVLSPGQKVLVYQPRASRGGEAPATTPVSAPVPAASGAAPAASATAR
CCHHHHHHHCHHEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]