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The map label for this gene is cmpR [H]

Identifier: 120609996

GI number: 120609996

Start: 1436145

End: 1437056

Strand: Reverse

Name: cmpR [H]

Synonym: Aave_1309

Alternate gene names: 120609996

Gene position: 1437056-1436145 (Counterclockwise)

Preceding gene: 120610002

Following gene: 120609995

Centisome position: 26.85

GC content: 69.96

Gene sequence:

>912_bases
TTGGAAACAACCATTGATCTAGAGCAGCTCCGCACCTTCGCCCTGGTGCTCGAGCTGGGGAGTTTTTCGGCGGCGGCGGA
ACGACTGGGGCTCACCCAGCCCGCCGTCAGTGTCCAAGTCAAGAAGCTGGAGCGCGCGCTGTCCGTGCGGCTGGTGGAAC
GCGTGGGAAGGCGCGTGAGCGCCACGCCCGCCGGCACCGACCTGCTCGCCCAGGTGCCCCACGTGGCGACCGCGGTGGCC
AACGCGGTGAGCGCGGCGACATTCCATGCCGCCGGGGTGTCCGGCACCGTGCGCCTGGGCACGGGCCTCACGCCCTGCCT
CTACTTCCTGCCGGGGGTGCTGCGCGACCTGCGCAAGCGCTATCCGTCGCTGCAGATCGTCGTGAGCACGGGCAACACGG
AGGACTACGTACGCCAGGTCGAGGGCAACATCGTCGATGTCGCCCTCGTCACGCTGCCCGTCAACTCCCGCGCGATCGCC
GCGACGCCGGTGCTGGAGGACGATTTCGTGGCCATCTGCCGGCGCGGAACCTGCCAGTGGCCCGACGCCGTGACCGCCGA
GCTGCTCAGCGAGCAGCCGATGGTGAAGCTCGGCAACGGGACCACCACCCGCACCCTGGTGGACGAATGGCTGCGCCAGG
GCACGGGGCCGCTGCGGCCGCCGGCGATGGAGTTCGACAGCGTGGAAGCCATCAAGGCCATGGTCGCGGCGGGCCTGGGC
TGCGCGGTGCTGCCCCGCATGGCCGTGACCGGGCCGGGCAAGCACAAGGACCTGGAGATGCGTCCGCTCGAACCGAAGCT
GCGGCGCACCCTGGCCTTCATCCTGCGGCAGGACAAGCCGGTGAACCGGGGCCTGAAGAAGGTGCTGGAAGCCATCGCGG
ACGGCGCCCGCGCCTTCAAGTCCAAGGACTGA

Upstream 100 bases:

>100_bases
CAATCTTGTTGTGCGGATGGACTGACTTTCTGCTTCAATCTTCTTTCCGAGGCTTCCATAAGAGAAGTTTTTCTTTCTTA
TACGAAACATAAAAATCATT

Downstream 100 bases:

>100_bases
CGCGCCTGCGCGCCGCCGGGGCTTTCCCGGAGACGGGGCGTTCCATGCCACGGCACCCGCCGGCGCGGGCGCCGGGTATC
CTGCGGGCGGTGAACTACGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
METTIDLEQLRTFALVLELGSFSAAAERLGLTQPAVSVQVKKLERALSVRLVERVGRRVSATPAGTDLLAQVPHVATAVA
NAVSAATFHAAGVSGTVRLGTGLTPCLYFLPGVLRDLRKRYPSLQIVVSTGNTEDYVRQVEGNIVDVALVTLPVNSRAIA
ATPVLEDDFVAICRRGTCQWPDAVTAELLSEQPMVKLGNGTTTRTLVDEWLRQGTGPLRPPAMEFDSVEAIKAMVAAGLG
CAVLPRMAVTGPGKHKDLEMRPLEPKLRRTLAFILRQDKPVNRGLKKVLEAIADGARAFKSKD

Sequences:

>Translated_303_residues
METTIDLEQLRTFALVLELGSFSAAAERLGLTQPAVSVQVKKLERALSVRLVERVGRRVSATPAGTDLLAQVPHVATAVA
NAVSAATFHAAGVSGTVRLGTGLTPCLYFLPGVLRDLRKRYPSLQIVVSTGNTEDYVRQVEGNIVDVALVTLPVNSRAIA
ATPVLEDDFVAICRRGTCQWPDAVTAELLSEQPMVKLGNGTTTRTLVDEWLRQGTGPLRPPAMEFDSVEAIKAMVAAGLG
CAVLPRMAVTGPGKHKDLEMRPLEPKLRRTLAFILRQDKPVNRGLKKVLEAIADGARAFKSKD
>Mature_303_residues
METTIDLEQLRTFALVLELGSFSAAAERLGLTQPAVSVQVKKLERALSVRLVERVGRRVSATPAGTDLLAQVPHVATAVA
NAVSAATFHAAGVSGTVRLGTGLTPCLYFLPGVLRDLRKRYPSLQIVVSTGNTEDYVRQVEGNIVDVALVTLPVNSRAIA
ATPVLEDDFVAICRRGTCQWPDAVTAELLSEQPMVKLGNGTTTRTLVDEWLRQGTGPLRPPAMEFDSVEAIKAMVAAGLG
CAVLPRMAVTGPGKHKDLEMRPLEPKLRRTLAFILRQDKPVNRGLKKVLEAIADGARAFKSKD

Specific function: Activates transcription of the cmpABCD operon under carbon dioxide-limited conditions. Specifically binds to the cmpR- cmpA intergenic region [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788481, Length=287, Percent_Identity=32.7526132404181, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI145693105, Length=280, Percent_Identity=27.1428571428571, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1788748, Length=292, Percent_Identity=28.0821917808219, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790399, Length=289, Percent_Identity=27.3356401384083, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI87082132, Length=260, Percent_Identity=28.4615384615385, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787806, Length=297, Percent_Identity=24.9158249158249, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI157672245, Length=289, Percent_Identity=25.6055363321799, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1787530, Length=260, Percent_Identity=28.8461538461538, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1787879, Length=249, Percent_Identity=26.9076305220884, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786401, Length=158, Percent_Identity=32.9113924050633, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789506, Length=174, Percent_Identity=26.4367816091954, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790208, Length=253, Percent_Identity=25.6916996047431, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1788297, Length=256, Percent_Identity=25, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32595; Mature: 32595

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: PS50931 HTH_LYSR ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METTIDLEQLRTFALVLELGSFSAAAERLGLTQPAVSVQVKKLERALSVRLVERVGRRVS
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
ATPAGTDLLAQVPHVATAVANAVSAATFHAAGVSGTVRLGTGLTPCLYFLPGVLRDLRKR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHH
YPSLQIVVSTGNTEDYVRQVEGNIVDVALVTLPVNSRAIAATPVLEDDFVAICRRGTCQW
CCCEEEEEECCCHHHHHHHHCCCEEEEEEEEEECCCCCEEECCCCCHHHHHHHCCCCCCC
PDAVTAELLSEQPMVKLGNGTTTRTLVDEWLRQGTGPLRPPAMEFDSVEAIKAMVAAGLG
CHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCC
CAVLPRMAVTGPGKHKDLEMRPLEPKLRRTLAFILRQDKPVNRGLKKVLEAIADGARAFK
HHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHC
SKD
CCC
>Mature Secondary Structure
METTIDLEQLRTFALVLELGSFSAAAERLGLTQPAVSVQVKKLERALSVRLVERVGRRVS
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
ATPAGTDLLAQVPHVATAVANAVSAATFHAAGVSGTVRLGTGLTPCLYFLPGVLRDLRKR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHH
YPSLQIVVSTGNTEDYVRQVEGNIVDVALVTLPVNSRAIAATPVLEDDFVAICRRGTCQW
CCCEEEEEECCCHHHHHHHHCCCEEEEEEEEEECCCCCEEECCCCCHHHHHHHCCCCCCC
PDAVTAELLSEQPMVKLGNGTTTRTLVDEWLRQGTGPLRPPAMEFDSVEAIKAMVAAGLG
CHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCC
CAVLPRMAVTGPGKHKDLEMRPLEPKLRRTLAFILRQDKPVNRGLKKVLEAIADGARAFK
HHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHC
SKD
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]