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The map label for this gene is ywbI [H]

Identifier: 120609911

GI number: 120609911

Start: 1349182

End: 1350117

Strand: Reverse

Name: ywbI [H]

Synonym: Aave_1224

Alternate gene names: 120609911

Gene position: 1350117-1349182 (Counterclockwise)

Preceding gene: 120609912

Following gene: 120609910

Centisome position: 25.22

GC content: 71.69

Gene sequence:

>936_bases
ATGAAAAATCCCGACCGCCATTTCGCGCGCCGCATCGACCTGACCTCGCTGCAGCTGTTCGTGGCCGTCTGCGAGCTGGG
CAGCATCGGTCGCGCCGCGGAGCGCGAATTCATCGCGGCCTCCGCGGTCAGCAAGCGCCTGTCGGACCTGGAGACGGCCG
TGGGCTCCGCGCTGCTGTACCGCCACAGCCGGGGCGTGACGCTGACGCCGGCGGGCGAGAGCCTGCTGCACCATGCGCGC
ACCGTGCTCTTCGGGCTGGAGCGCATGCAGGGCGAACTGAGCGAATACGCCGACGGCGTGCGCGGCCATGTGCGGGTGCA
CGCGAACATTTCCGCCATCGTGCAGTTCCTGCCCGAGGATCTCGGGGCCTTCGCCAGGGAACACGCCCAGGTCAAGATCG
ACCTGCAGGAGCACCTGAGCCCCGACGTCCTGCATGCCGTGCGCGAAGGCGCCGCCGACCTGGGCCTGTGCCATACCGGC
GACGGCGCCGAACCCCAGGAACTGCAGAGCCGCCCCTACCGCAGCGACCGGCTGGTGCTCGTGGTGCCCGAGGGGCATCC
GCTGGCGGGACGGCCCGCGGTCCGGTTCGAGGACGTGCTCGACTGGGACATCGTCGGGCTGCAGGCCAACAGCAGCATCA
GCCTCGCCATGCGGCGCGGCGCGGCGCGTGCCGGGCGGCCCCTGCGCCAGCGCATCCAGGTCACGGGCCTGGACGCCATG
TGCCGCATGATCGACAACGGCCTCGGCATCGGGCTGCTCCCCGACCGGGCCTTCGCGCTGATGCGCGGCGTGGGGCGGCT
GCAGCCGGTCGCCCTGGACGAACCCTGGGCGGAACGCTCGCTGCGGCTCGTCGCGCGTGACTTCGGCAGCCTGCCCGTGA
CGGCGCGGCTGCTGGCCGACCATCTGGCACCGCCGGAACGCAAGACCTCTTCCTAG

Upstream 100 bases:

>100_bases
TCGCGATGTGCGACGTCGTGTTTCGCGACGGCCCGCCCCATCCATACAGGAGAAAATACCACCCAGACTTCTCTTTCGAA
GAAGCCCGACGCCCCGCCCC

Downstream 100 bases:

>100_bases
AATCCACCCACCCATCCCCACCCTGAACCAGCCCAAGAGAGAACACACCATGGGACGCACCCTCTACGACAAGATCTGGG
ACGAGCATGTCGTCCATACC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MKNPDRHFARRIDLTSLQLFVAVCELGSIGRAAEREFIAASAVSKRLSDLETAVGSALLYRHSRGVTLTPAGESLLHHAR
TVLFGLERMQGELSEYADGVRGHVRVHANISAIVQFLPEDLGAFAREHAQVKIDLQEHLSPDVLHAVREGAADLGLCHTG
DGAEPQELQSRPYRSDRLVLVVPEGHPLAGRPAVRFEDVLDWDIVGLQANSSISLAMRRGAARAGRPLRQRIQVTGLDAM
CRMIDNGLGIGLLPDRAFALMRGVGRLQPVALDEPWAERSLRLVARDFGSLPVTARLLADHLAPPERKTSS

Sequences:

>Translated_311_residues
MKNPDRHFARRIDLTSLQLFVAVCELGSIGRAAEREFIAASAVSKRLSDLETAVGSALLYRHSRGVTLTPAGESLLHHAR
TVLFGLERMQGELSEYADGVRGHVRVHANISAIVQFLPEDLGAFAREHAQVKIDLQEHLSPDVLHAVREGAADLGLCHTG
DGAEPQELQSRPYRSDRLVLVVPEGHPLAGRPAVRFEDVLDWDIVGLQANSSISLAMRRGAARAGRPLRQRIQVTGLDAM
CRMIDNGLGIGLLPDRAFALMRGVGRLQPVALDEPWAERSLRLVARDFGSLPVTARLLADHLAPPERKTSS
>Mature_311_residues
MKNPDRHFARRIDLTSLQLFVAVCELGSIGRAAEREFIAASAVSKRLSDLETAVGSALLYRHSRGVTLTPAGESLLHHAR
TVLFGLERMQGELSEYADGVRGHVRVHANISAIVQFLPEDLGAFAREHAQVKIDLQEHLSPDVLHAVREGAADLGLCHTG
DGAEPQELQSRPYRSDRLVLVVPEGHPLAGRPAVRFEDVLDWDIVGLQANSSISLAMRRGAARAGRPLRQRIQVTGLDAM
CRMIDNGLGIGLLPDRAFALMRGVGRLQPVALDEPWAERSLRLVARDFGSLPVTARLLADHLAPPERKTSS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693105, Length=263, Percent_Identity=24.3346007604563, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI87081904, Length=201, Percent_Identity=31.8407960199005, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1786713, Length=256, Percent_Identity=29.6875, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1787601, Length=195, Percent_Identity=25.6410256410256, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1787879, Length=286, Percent_Identity=25.8741258741259, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787806, Length=276, Percent_Identity=25.3623188405797, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1788748, Length=303, Percent_Identity=28.3828382838284, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790208, Length=250, Percent_Identity=27.6, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788887, Length=287, Percent_Identity=27.8745644599303, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI157672245, Length=270, Percent_Identity=25.5555555555556, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI145693193, Length=142, Percent_Identity=31.6901408450704, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI2367136, Length=256, Percent_Identity=25, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786401, Length=177, Percent_Identity=28.8135593220339, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787530, Length=252, Percent_Identity=23.015873015873, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1789506, Length=240, Percent_Identity=23.3333333333333, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1790262, Length=188, Percent_Identity=28.1914893617021, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33971; Mature: 33971

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNPDRHFARRIDLTSLQLFVAVCELGSIGRAAEREFIAASAVSKRLSDLETAVGSALLY
CCCCHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RHSRGVTLTPAGESLLHHARTVLFGLERMQGELSEYADGVRGHVRVHANISAIVQFLPED
HCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHH
LGAFAREHAQVKIDLQEHLSPDVLHAVREGAADLGLCHTGDGAEPQELQSRPYRSDRLVL
HHHHHHHCCEEEEEHHHCCCHHHHHHHHHCHHHCCEEECCCCCCHHHHHCCCCCCCCEEE
VVPEGHPLAGRPAVRFEDVLDWDIVGLQANSSISLAMRRGAARAGRPLRQRIQVTGLDAM
EECCCCCCCCCCCCHHHHHCCEEEEEEECCCCHHHHHHHCHHHCCCHHHHHHHHCCHHHH
CRMIDNGLGIGLLPDRAFALMRGVGRLQPVALDEPWAERSLRLVARDFGSLPVTARLLAD
HHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
HLAPPERKTSS
HCCCCCCCCCC
>Mature Secondary Structure
MKNPDRHFARRIDLTSLQLFVAVCELGSIGRAAEREFIAASAVSKRLSDLETAVGSALLY
CCCCHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RHSRGVTLTPAGESLLHHARTVLFGLERMQGELSEYADGVRGHVRVHANISAIVQFLPED
HCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHH
LGAFAREHAQVKIDLQEHLSPDVLHAVREGAADLGLCHTGDGAEPQELQSRPYRSDRLVL
HHHHHHHCCEEEEEHHHCCCHHHHHHHHHCHHHCCEEECCCCCCHHHHHCCCCCCCCEEE
VVPEGHPLAGRPAVRFEDVLDWDIVGLQANSSISLAMRRGAARAGRPLRQRIQVTGLDAM
EECCCCCCCCCCCCHHHHHCCEEEEEEECCCCHHHHHHHCHHHCCCHHHHHHHHCCHHHH
CRMIDNGLGIGLLPDRAFALMRGVGRLQPVALDEPWAERSLRLVARDFGSLPVTARLLAD
HHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
HLAPPERKTSS
HCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]