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The map label for this gene is xlnD [H]

Identifier: 120609842

GI number: 120609842

Start: 1274213

End: 1275451

Strand: Direct

Name: xlnD [H]

Synonym: Aave_1154

Alternate gene names: 120609842

Gene position: 1274213-1275451 (Clockwise)

Preceding gene: 120609841

Following gene: 120609846

Centisome position: 23.8

GC content: 74.25

Gene sequence:

>1239_bases
ATGCAACATACACGACAGACCGTGCTCCTGGTCGCGGGCGGCGGCATCGGAGGCCTGTCCGCGGCCCTCGCGGCTTCGCG
CGCGGGCTGGTCGGTGGACCTGTACGAGCGCGCCCCCGTTTTCAGCGAAGTGGGCGCGGGAGTGCAGCTCGGGCCGAATG
CGGTGAGGCTGCTGCATGCCTGGGGACTGGAGTCCGCGCTACAGGCCGTCGCCGCGTATCCCGAACGGCTGCAGGTGCGC
AGCGCGCTGGATGGCCGGGTGCTGGCGGCCATGCCGCTGGGCACGGCCATCGCGTCCCGCTACGGAGCCCCCTATGTGGC
AATCCACCGCGCGGACCTGCACGGCCTGCTGCTGGAGGCCGTGCGCGGACGTCCCGGCGTCGAGCTGCATCTCGGCGAGA
CCATCGCGGACCACTGGGAGCACGCAGCAGGCGTCACGGTGCGAACGGTGGCGGGGCACCCGGTGCAAGGGGCCGCCTTC
GTCGGGGCCGACGGACTGCGCAGCGCCACGCGCGCCCGGATGCTGGGGGCGGAGCCCGCGCGGATATCCGGCCACCTGGC
CTACCGGACGGTAGTGCCGCAGCAGGCACTGCCCGAGCGCCTGCGCACGACGCAGGTCACGGCCTGGCTGGGGCCGGGCC
TGCATGTGGTCCAGTATCCGGTGCGCAGGGGCGAACTCATGAACATCGTCGCCATCCGCCATGGACGGGCGCCGGAGGAC
CTCGACCACTGGGACCATGCCGGCAACGCGGGGGACCTGGAAGGGGCGCTGCGCCCCACCTGCACGGAGCTGCAAGACCT
GGTGCGCGCCGTGCCGCAAGCGGGCGGCGGCTGGCGCCTCTGGCCGCTGTCCGACCGGCCTCCGCTGTCCGGACCGCATG
AGATGGCGCGTGGCAGGGTGGCCTTGCTGGGCGATGCCGCCCATCCGATGCGGCCCTATCTGGCGCAGGGCGCCGGCATG
GCGATCGAGGATGCCGCCGCGCTCGGGCTGGCCCTGTCCGGTGGCGGCGGCGACGTGCCGGGCCGCCTGGCGCGCTACGC
GGCCGGACGGTGGCGGCGCAATGCGCGCGTGCAGGCCAGGGCCGAGCGCAACGGCAGGATCTTCCATGCCAGGGGCCCCG
TGCGCTGGGCCCGCGACGCCTCCCTGCGCCTGCTCGGAGCGCGTCTGCTCGACCAGCCCTGGCTTTACCGGGGCGAGGCC
GCGGAAGCGATGGCCGCAGGTCCCGGCAGCAGCCGGTAG

Upstream 100 bases:

>100_bases
GAGAGGGCGTTGCGCCCCGCGCTGTGATTCTCCGCCACGGCGGCGCCCGGGTTTGACCTGCCTCGCCTCCGGCGCCCGGG
CCAGCCCGCACAATCGGCCC

Downstream 100 bases:

>100_bases
GCGAGCGCGCCCGCGGCGAGCAGCCCGGCGATGGTGCACAGCACCGCCGTATAGGTGCCAGCGTACCCCGATTACCCGCC
CTGGCAATGCGCCGAACGCG

Product: FAD-binding monooxygenase

Products: NA

Alternate protein names: Constitutive 3-hydroxybenzoate 6-hydroxylase [H]

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MQHTRQTVLLVAGGGIGGLSAALAASRAGWSVDLYERAPVFSEVGAGVQLGPNAVRLLHAWGLESALQAVAAYPERLQVR
SALDGRVLAAMPLGTAIASRYGAPYVAIHRADLHGLLLEAVRGRPGVELHLGETIADHWEHAAGVTVRTVAGHPVQGAAF
VGADGLRSATRARMLGAEPARISGHLAYRTVVPQQALPERLRTTQVTAWLGPGLHVVQYPVRRGELMNIVAIRHGRAPED
LDHWDHAGNAGDLEGALRPTCTELQDLVRAVPQAGGGWRLWPLSDRPPLSGPHEMARGRVALLGDAAHPMRPYLAQGAGM
AIEDAAALGLALSGGGGDVPGRLARYAAGRWRRNARVQARAERNGRIFHARGPVRWARDASLRLLGARLLDQPWLYRGEA
AEAMAAGPGSSR

Sequences:

>Translated_412_residues
MQHTRQTVLLVAGGGIGGLSAALAASRAGWSVDLYERAPVFSEVGAGVQLGPNAVRLLHAWGLESALQAVAAYPERLQVR
SALDGRVLAAMPLGTAIASRYGAPYVAIHRADLHGLLLEAVRGRPGVELHLGETIADHWEHAAGVTVRTVAGHPVQGAAF
VGADGLRSATRARMLGAEPARISGHLAYRTVVPQQALPERLRTTQVTAWLGPGLHVVQYPVRRGELMNIVAIRHGRAPED
LDHWDHAGNAGDLEGALRPTCTELQDLVRAVPQAGGGWRLWPLSDRPPLSGPHEMARGRVALLGDAAHPMRPYLAQGAGM
AIEDAAALGLALSGGGGDVPGRLARYAAGRWRRNARVQARAERNGRIFHARGPVRWARDASLRLLGARLLDQPWLYRGEA
AEAMAAGPGSSR
>Mature_412_residues
MQHTRQTVLLVAGGGIGGLSAALAASRAGWSVDLYERAPVFSEVGAGVQLGPNAVRLLHAWGLESALQAVAAYPERLQVR
SALDGRVLAAMPLGTAIASRYGAPYVAIHRADLHGLLLEAVRGRPGVELHLGETIADHWEHAAGVTVRTVAGHPVQGAAF
VGADGLRSATRARMLGAEPARISGHLAYRTVVPQQALPERLRTTQVTAWLGPGLHVVQYPVRRGELMNIVAIRHGRAPED
LDHWDHAGNAGDLEGALRPTCTELQDLVRAVPQAGGGWRLWPLSDRPPLSGPHEMARGRVALLGDAAHPMRPYLAQGAGM
AIEDAAALGLALSGGGGDVPGRLARYAAGRWRRNARVQARAERNGRIFHARGPVRWARDASLRLLGARLLDQPWLYRGEA
AEAMAAGPGSSR

Specific function: Catalyzes the NAD- or NADP-dependent conversion of 3- hydroxybenzoate to gentisate. The affinity of the enzyme toward NAD is twice as high as for NADP. The enzyme shows higher specific activities against the intermediates in the degradation of 2,5- xyleno

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-hydroxybenzoate 6-hydroxylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: =1.14.13.24 [H]

Molecular weight: Translated: 43737; Mature: 43737

Theoretical pI: Translated: 10.92; Mature: 10.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHTRQTVLLVAGGGIGGLSAALAASRAGWSVDLYERAPVFSEVGAGVQLGPNAVRLLHA
CCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEHHHCCCCHHHHCCCCEECCHHHHHHHH
WGLESALQAVAAYPERLQVRSALDGRVLAAMPLGTAIASRYGAPYVAIHRADLHGLLLEA
HCHHHHHHHHHHCHHHHHHHHHCCCCEEEECCHHHHHHHHCCCCEEEEEECHHHHHHHHH
VRGRPGVELHLGETIADHWEHAAGVTVRTVAGHPVQGAAFVGADGLRSATRARMLGAEPA
HCCCCCEEEEECCHHHHHHHHHCCCEEEEECCCCCCCEEEECCCHHHHHHHHHHHCCCCC
RISGHLAYRTVVPQQALPERLRTTQVTAWLGPGLHVVQYPVRRGELMNIVAIRHGRAPED
HHCCEEEEEEECCHHHHHHHHHHHEEEEEECCCCEEEECCHHCCCEEEEEEEECCCCCCH
LDHWDHAGNAGDLEGALRPTCTELQDLVRAVPQAGGGWRLWPLSDRPPLSGPHEMARGRV
HHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHCCCE
ALLGDAAHPMRPYLAQGAGMAIEDAAALGLALSGGGGDVPGRLARYAAGRWRRNARVQAR
EEEECCCCCCCHHHHCCCCCEEHHHHHEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEE
AERNGRIFHARGPVRWARDASLRLLGARLLDQPWLYRGEAAEAMAAGPGSSR
ECCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCC
>Mature Secondary Structure
MQHTRQTVLLVAGGGIGGLSAALAASRAGWSVDLYERAPVFSEVGAGVQLGPNAVRLLHA
CCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEHHHCCCCHHHHCCCCEECCHHHHHHHH
WGLESALQAVAAYPERLQVRSALDGRVLAAMPLGTAIASRYGAPYVAIHRADLHGLLLEA
HCHHHHHHHHHHCHHHHHHHHHCCCCEEEECCHHHHHHHHCCCCEEEEEECHHHHHHHHH
VRGRPGVELHLGETIADHWEHAAGVTVRTVAGHPVQGAAFVGADGLRSATRARMLGAEPA
HCCCCCEEEEECCHHHHHHHHHCCCEEEEECCCCCCCEEEECCCHHHHHHHHHHHCCCCC
RISGHLAYRTVVPQQALPERLRTTQVTAWLGPGLHVVQYPVRRGELMNIVAIRHGRAPED
HHCCEEEEEEECCHHHHHHHHHHHEEEEEECCCCEEEECCHHCCCEEEEEEEECCCCCCH
LDHWDHAGNAGDLEGALRPTCTELQDLVRAVPQAGGGWRLWPLSDRPPLSGPHEMARGRV
HHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHCCCE
ALLGDAAHPMRPYLAQGAGMAIEDAAALGLALSGGGGDVPGRLARYAAGRWRRNARVQAR
EEEECCCCCCCHHHHCCCCCEEHHHHHEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEE
AERNGRIFHARGPVRWARDASLRLLGARLLDQPWLYRGEAAEAMAAGPGSSR
ECCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12909360 [H]