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The map label for this gene is speE [H]

Identifier: 120609760

GI number: 120609760

Start: 1170133

End: 1170897

Strand: Direct

Name: speE [H]

Synonym: Aave_1067

Alternate gene names: 120609760

Gene position: 1170133-1170897 (Clockwise)

Preceding gene: 120609759

Following gene: 120609761

Centisome position: 21.86

GC content: 70.46

Gene sequence:

>765_bases
ATGACCACCCGCAAGAAAGCCGCAGCCGCCGAGCTGCCCGAAGTCAGTGTTTCCGATGACGGCGACGTGCGCCACCTGCA
CCTGGGCACGCCCTGGATCCAGGGCTCCATGCGCATCGACGATCCCTTCGACATCGAACTGGAGTACGTGCAGCGCATGA
TGGCCTGGCTGCTGTTCGTCGAGCCCGCCAGCGTGGGCAAGCGGCATGCGATGCAGCTGGGCCTGGGCGCGGGTGCGATC
ACCAAGTTCTGCCACAAGAAGCTGCGCATGTGCTGCACGGCGATCGAGCTGAACCCACAGGTGCTGGCCGTGTGCCGCGC
GTGGTTCAAGCTGCCGCCCGACGGGCCGAAGCTGCGCGTGGTGCTGGCCGATGCCGCGCAGGAGATCCGCAAGCCCGAGT
GGCACGGCACGGTCGATGCGCTGGCGGTGGACCTGTACGACCACGAGGCCGCGGCGCCGGTGCTCGACAGCGCGGAGTTC
TACGCCGACTGCCGGGCGCTGCTCACCGAAGACGGCGCGATGACCGTGAACCTCTTCGGCCGCTCCTCCAGCTACGAGCG
CAGCCTCGCGCGCATGGCCGAGGCCTTCGGCGCCGACGCGCTCTGGGCCTTCAAGCCCACGCGCGAGGGCAACACGGTGG
TGCTGGCCCAGCGCACGCCCTTGCGGCCGCGCCGCGCGGACCTGCTGGCCCGCGCCGATGCGGTGCAGGCGCGGTGGGAC
CTGCCCGCGGCGAAGTGGCCGCGCGTGTTCAAGCCGGTGGAGTGA

Upstream 100 bases:

>100_bases
GCGCCTGCCCTCCACCAGCCCCGCGAACGCGTCGTGGAGCTTCGAGCGCAAGCGCGCCGCCTGGGCCGCGGCCTTCGCCC
CCTTTGGATTGATGGACTGA

Downstream 100 bases:

>100_bases
CGCGCGATGAGCCGCAGCCTGCCTCCTACCCTCCATGACGCCGCCGGGCCCGCGGCGCCGGCCGGCTTCGCGGGCCCCCT
CGAGTGGCGGCGCATCGTCG

Product: hypothetical protein

Products: NA

Alternate protein names: Putrescine aminopropyltransferase; PAPT; SPDSY [H]

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MTTRKKAAAAELPEVSVSDDGDVRHLHLGTPWIQGSMRIDDPFDIELEYVQRMMAWLLFVEPASVGKRHAMQLGLGAGAI
TKFCHKKLRMCCTAIELNPQVLAVCRAWFKLPPDGPKLRVVLADAAQEIRKPEWHGTVDALAVDLYDHEAAAPVLDSAEF
YADCRALLTEDGAMTVNLFGRSSSYERSLARMAEAFGADALWAFKPTREGNTVVLAQRTPLRPRRADLLARADAVQARWD
LPAAKWPRVFKPVE

Sequences:

>Translated_254_residues
MTTRKKAAAAELPEVSVSDDGDVRHLHLGTPWIQGSMRIDDPFDIELEYVQRMMAWLLFVEPASVGKRHAMQLGLGAGAI
TKFCHKKLRMCCTAIELNPQVLAVCRAWFKLPPDGPKLRVVLADAAQEIRKPEWHGTVDALAVDLYDHEAAAPVLDSAEF
YADCRALLTEDGAMTVNLFGRSSSYERSLARMAEAFGADALWAFKPTREGNTVVLAQRTPLRPRRADLLARADAVQARWD
LPAAKWPRVFKPVE
>Mature_253_residues
TTRKKAAAAELPEVSVSDDGDVRHLHLGTPWIQGSMRIDDPFDIELEYVQRMMAWLLFVEPASVGKRHAMQLGLGAGAIT
KFCHKKLRMCCTAIELNPQVLAVCRAWFKLPPDGPKLRVVLADAAQEIRKPEWHGTVDALAVDLYDHEAAAPVLDSAEFY
ADCRALLTEDGAMTVNLFGRSSSYERSLARMAEAFGADALWAFKPTREGNTVVLAQRTPLRPRRADLLARADAVQARWDL
PAAKWPRVFKPVE

Specific function: Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor [H]

COG id: COG0421

COG function: function code E; Spermidine synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the spermidine/spermine synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001045 [H]

Pfam domain/function: PF01564 Spermine_synth [H]

EC number: =2.5.1.16 [H]

Molecular weight: Translated: 28263; Mature: 28132

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTRKKAAAAELPEVSVSDDGDVRHLHLGTPWIQGSMRIDDPFDIELEYVQRMMAWLLFV
CCCCHHHHHHCCCCCCCCCCCCEEEEECCCCEECCCEECCCCCCCCHHHHHHHHHHHHHC
EPASVGKRHAMQLGLGAGAITKFCHKKLRMCCTAIELNPQVLAVCRAWFKLPPDGPKLRV
CCHHHCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEE
VLADAAQEIRKPEWHGTVDALAVDLYDHEAAAPVLDSAEFYADCRALLTEDGAMTVNLFG
EEHHHHHHHCCCCCCCCHHHEEEEHHCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEC
RSSSYERSLARMAEAFGADALWAFKPTREGNTVVLAQRTPLRPRRADLLARADAVQARWD
CCCHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCC
LPAAKWPRVFKPVE
CCCCCCCCCCCCCC
>Mature Secondary Structure 
TTRKKAAAAELPEVSVSDDGDVRHLHLGTPWIQGSMRIDDPFDIELEYVQRMMAWLLFV
CCCHHHHHHCCCCCCCCCCCCEEEEECCCCEECCCEECCCCCCCCHHHHHHHHHHHHHC
EPASVGKRHAMQLGLGAGAITKFCHKKLRMCCTAIELNPQVLAVCRAWFKLPPDGPKLRV
CCHHHCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEE
VLADAAQEIRKPEWHGTVDALAVDLYDHEAAAPVLDSAEFYADCRALLTEDGAMTVNLFG
EEHHHHHHHCCCCCCCCHHHEEEEHHCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEC
RSSSYERSLARMAEAFGADALWAFKPTREGNTVVLAQRTPLRPRRADLLARADAVQARWD
CCCHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCC
LPAAKWPRVFKPVE
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]