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The map label for this gene is pncB [H]

Identifier: 120609670

GI number: 120609670

Start: 1072054

End: 1073250

Strand: Reverse

Name: pncB [H]

Synonym: Aave_0976

Alternate gene names: 120609670

Gene position: 1073250-1072054 (Counterclockwise)

Preceding gene: 120609671

Following gene: 120609669

Centisome position: 20.05

GC content: 67.34

Gene sequence:

>1197_bases
ATGGCACCGATCATCCAGAGCCTGCTGGACACCGACCTCTACAAGTTCACGATGTGGCAGGCGTTGCTGCACCGCCACCC
GCAGACGCAGGCGGAGTACCGCTTCGTCTGCCGCAATGCGCCGGCTTTTCCGCTCGCGGAACTGCTGCCGCAGGTCAACG
CGGAACTGGACGCACTGTGCGCCTTGCGCTTCTCCCCGGACGAGCTGGATTACCTCGGCGGGCTGCGCTACATCAAGAGC
GATTTCGTGGATTTCCTGCGCATCTTCCAGTTCCAGCGCGCCTTCATCGAGGCGCGCGCGGAAGGGGAGCAGCTGTCGAT
CGTGGCACGCGGGCCGCAGGTGCATGTGATGGGCTTCGAGATCTTCGTGCTGGCCATCGTGAACGAGCTGTATTTCCGCC
GGCTCGGCGGTGGCGCGGACGTGCTGCGGGAAGGCCGCCGCCGGCTGACCGCGAAGATCGCGCGGGTGCGGGCGCTGGCA
GCGGAGGCGCCGCGTACCCATCCGTTCGAAATGTTCGACTTCGGCCTGCGCCGGCGCTACGGCGCCGCCTGGCAGCGCGA
GGTGGTGCAGACCTTCGCCGCGCAGGCTCCGCAATGGTTCAAGGGCACGTCGAACGTGCTGCTGGCCCGCGATCTGCAAC
TGGTGCCCATCGGCACCATGGCCCACGAGTACCTGCAGAGCTACCAGGCGCTGGGCGTGCGGCTGCGCGATTTCCAGAAG
GCGGCACTGGAGGACTGGGTGCAGGAATACCGCGGCGACCTCGGCATCGCGCTCACCGACACGGTCGGCATGGACGCCTT
CCTCGCGGATTTCGACCTGTACTTCGCCAAGCTCTTCGACGGCCTGCGGCACGACTCGGGCGACCCGGTCGCCTGGGGCG
AAAAGGCCCTGGCGCACTATGCGCGGCTGCGCATCGACGCACACGGCAAGCGCCTGGTGTTCTCCGACGGGCTCGACGTG
GAGCGCGCGCTGGCGCTCCACCGCCACTTCGGCGACCGTGTGCAGCTGGGCTTCGGCATCGGCACGCAGCTCAGCAACGA
CCTGGGGCCGCGCCCGCTCAACATCGTCATGAAAATCGTGCGTGCCAATGGCCAGCCGGTTGCGAAACTGTCCGACAGCC
CGGGCAAGACGCTGTGCGACGATGAAACCTACCTCGCCTACCTGCGGCAGGTATTCGGCCTGCCGCCCGAGGCCTGA

Upstream 100 bases:

>100_bases
TGCGCGCGCAGGGCGTGCGGCTCGCGGCCGCGGACGATTGGGCTGCCTAGCGCGGGCTGCCCGGCCTTTCCTTCTTCCAG
CCTTCCAGGAGCACGCACGC

Downstream 100 bases:

>100_bases
GCCTTTTCGCCTTGCCCCCAACAACCTCCAAGGAAACGACATGCTCCGGATCACCCTTGCCCAGCTCAACCTCACCGTGG
GCGACATCGAAGGCAACGTG

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase [H]

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MAPIIQSLLDTDLYKFTMWQALLHRHPQTQAEYRFVCRNAPAFPLAELLPQVNAELDALCALRFSPDELDYLGGLRYIKS
DFVDFLRIFQFQRAFIEARAEGEQLSIVARGPQVHVMGFEIFVLAIVNELYFRRLGGGADVLREGRRRLTAKIARVRALA
AEAPRTHPFEMFDFGLRRRYGAAWQREVVQTFAAQAPQWFKGTSNVLLARDLQLVPIGTMAHEYLQSYQALGVRLRDFQK
AALEDWVQEYRGDLGIALTDTVGMDAFLADFDLYFAKLFDGLRHDSGDPVAWGEKALAHYARLRIDAHGKRLVFSDGLDV
ERALALHRHFGDRVQLGFGIGTQLSNDLGPRPLNIVMKIVRANGQPVAKLSDSPGKTLCDDETYLAYLRQVFGLPPEA

Sequences:

>Translated_398_residues
MAPIIQSLLDTDLYKFTMWQALLHRHPQTQAEYRFVCRNAPAFPLAELLPQVNAELDALCALRFSPDELDYLGGLRYIKS
DFVDFLRIFQFQRAFIEARAEGEQLSIVARGPQVHVMGFEIFVLAIVNELYFRRLGGGADVLREGRRRLTAKIARVRALA
AEAPRTHPFEMFDFGLRRRYGAAWQREVVQTFAAQAPQWFKGTSNVLLARDLQLVPIGTMAHEYLQSYQALGVRLRDFQK
AALEDWVQEYRGDLGIALTDTVGMDAFLADFDLYFAKLFDGLRHDSGDPVAWGEKALAHYARLRIDAHGKRLVFSDGLDV
ERALALHRHFGDRVQLGFGIGTQLSNDLGPRPLNIVMKIVRANGQPVAKLSDSPGKTLCDDETYLAYLRQVFGLPPEA
>Mature_397_residues
APIIQSLLDTDLYKFTMWQALLHRHPQTQAEYRFVCRNAPAFPLAELLPQVNAELDALCALRFSPDELDYLGGLRYIKSD
FVDFLRIFQFQRAFIEARAEGEQLSIVARGPQVHVMGFEIFVLAIVNELYFRRLGGGADVLREGRRRLTAKIARVRALAA
EAPRTHPFEMFDFGLRRRYGAAWQREVVQTFAAQAPQWFKGTSNVLLARDLQLVPIGTMAHEYLQSYQALGVRLRDFQKA
ALEDWVQEYRGDLGIALTDTVGMDAFLADFDLYFAKLFDGLRHDSGDPVAWGEKALAHYARLRIDAHGKRLVFSDGLDVE
RALALHRHFGDRVQLGFGIGTQLSNDLGPRPLNIVMKIVRANGQPVAKLSDSPGKTLCDDETYLAYLRQVFGLPPEA

Specific function: NAD biosynthesis; nicotinamide to NaMN; second step. [C]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family [H]

Homologues:

Organism=Escherichia coli, GI1787162, Length=395, Percent_Identity=44.0506329113924, Blast_Score=320, Evalue=7e-89,
Organism=Saccharomyces cerevisiae, GI6324783, Length=410, Percent_Identity=29.5121951219512, Blast_Score=174, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006406
- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR002638 [H]

Pfam domain/function: PF04095 NAPRTase [H]

EC number: =2.4.2.11 [H]

Molecular weight: Translated: 45013; Mature: 44882

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPIIQSLLDTDLYKFTMWQALLHRHPQTQAEYRFVCRNAPAFPLAELLPQVNAELDALC
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHH
ALRFSPDELDYLGGLRYIKSDFVDFLRIFQFQRAFIEARAEGEQLSIVARGPQVHVMGFE
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCEEEEEHHH
IFVLAIVNELYFRRLGGGADVLREGRRRLTAKIARVRALAAEAPRTHPFEMFDFGLRRRY
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
GAAWQREVVQTFAAQAPQWFKGTSNVLLARDLQLVPIGTMAHEYLQSYQALGVRLRDFQK
CHHHHHHHHHHHHHCCCHHHCCCCCEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
AALEDWVQEYRGDLGIALTDTVGMDAFLADFDLYFAKLFDGLRHDSGDPVAWGEKALAHY
HHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
ARLRIDAHGKRLVFSDGLDVERALALHRHFGDRVQLGFGIGTQLSNDLGPRPLNIVMKIV
HHHEEECCCCEEEEECCCCHHHHHHHHHHCCCCEEEEECCCCHHCCCCCCCHHHHHHHHH
RANGQPVAKLSDSPGKTLCDDETYLAYLRQVFGLPPEA
HCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
APIIQSLLDTDLYKFTMWQALLHRHPQTQAEYRFVCRNAPAFPLAELLPQVNAELDALC
CHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHH
ALRFSPDELDYLGGLRYIKSDFVDFLRIFQFQRAFIEARAEGEQLSIVARGPQVHVMGFE
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCEEEEEHHH
IFVLAIVNELYFRRLGGGADVLREGRRRLTAKIARVRALAAEAPRTHPFEMFDFGLRRRY
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
GAAWQREVVQTFAAQAPQWFKGTSNVLLARDLQLVPIGTMAHEYLQSYQALGVRLRDFQK
CHHHHHHHHHHHHHCCCHHHCCCCCEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
AALEDWVQEYRGDLGIALTDTVGMDAFLADFDLYFAKLFDGLRHDSGDPVAWGEKALAHY
HHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
ARLRIDAHGKRLVFSDGLDVERALALHRHFGDRVQLGFGIGTQLSNDLGPRPLNIVMKIV
HHHEEECCCCEEEEECCCCHHHHHHHHHHCCCCEEEEECCCCHHCCCCCCCHHHHHHHHH
RANGQPVAKLSDSPGKTLCDDETYLAYLRQVFGLPPEA
HCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA