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The map label for this gene is groS

Identifier: 120609640

GI number: 120609640

Start: 1032076

End: 1032366

Strand: Reverse

Name: groS

Synonym: Aave_0946

Alternate gene names: 120609640

Gene position: 1032366-1032076 (Counterclockwise)

Preceding gene: 120609658

Following gene: 120609639

Centisome position: 19.29

GC content: 61.17

Gene sequence:

>291_bases
ATGAGCCTTCGCCCCCTGCACGATCGCGTGATCGTCAAGCGCATTGAAAGCGAAACCACGACCGCCTCCGGCATCGTGAT
CCCCGACAACGCTGCCGAGAAGCCCGATCAAGGCGTAGTCCTGGCCGTGGGCCCTGGCAAGAAGAACGACAAGGGTGAAC
TGAGCGTGCTGAGCGTCAAGGTCGGCGACCGCGTGCTGTTCGGCAAGTACTCGGGCCAGACCGTCAAGGTCAACGGCGAC
GAACTGCTGGTGATGAAGGAAGACGACCTGTTCGCAGTCGTCGAGAAGTGA

Upstream 100 bases:

>100_bases
CTAACAACCGTGTGGGACACGGCCGCTGAAGATCCCGACGCCCGCTTTCCGCGGGCGTCCTGTCGATGTCGCAATCCTTA
TTGAACCAGGAGAGATGCAA

Downstream 100 bases:

>100_bases
CCGCTTCGCGGATCACATCCTCTTCCAACTTCCTGTTGACTGAATCCGGAGAAACAAAATGGCAGCAAAAGACGTAGTTT
TCGGCGGCGAAGCCCGCGCT

Product: chaperonin Cpn10

Products: NA

Alternate protein names: GroES protein; Protein Cpn10

Number of amino acids: Translated: 96; Mature: 95

Protein sequence:

>96_residues
MSLRPLHDRVIVKRIESETTTASGIVIPDNAAEKPDQGVVLAVGPGKKNDKGELSVLSVKVGDRVLFGKYSGQTVKVNGD
ELLVMKEDDLFAVVEK

Sequences:

>Translated_96_residues
MSLRPLHDRVIVKRIESETTTASGIVIPDNAAEKPDQGVVLAVGPGKKNDKGELSVLSVKVGDRVLFGKYSGQTVKVNGD
ELLVMKEDDLFAVVEK
>Mature_95_residues
SLRPLHDRVIVKRIESETTTASGIVIPDNAAEKPDQGVVLAVGPGKKNDKGELSVLSVKVGDRVLFGKYSGQTVKVNGDE
LLVMKEDDLFAVVEK

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family

Homologues:

Organism=Escherichia coli, GI1790585, Length=96, Percent_Identity=51.0416666666667, Blast_Score=91, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17555568, Length=92, Percent_Identity=42.3913043478261, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324594, Length=96, Percent_Identity=41.6666666666667, Blast_Score=77, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21358317, Length=94, Percent_Identity=45.7446808510638, Blast_Score=75, Evalue=8e-15,
Organism=Drosophila melanogaster, GI21356029, Length=94, Percent_Identity=42.5531914893617, Blast_Score=72, Evalue=6e-14,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): CH10_ACIAC (A1TKQ6)

Other databases:

- EMBL:   CP000512
- RefSeq:   YP_969318.1
- ProteinModelPortal:   A1TKQ6
- SMR:   A1TKQ6
- STRING:   A1TKQ6
- GeneID:   4665301
- GenomeReviews:   CP000512_GR
- KEGG:   aav:Aave_0946
- NMPDR:   fig|397945.5.peg.824
- eggNOG:   COG0234
- HOGENOM:   HBG703377
- OMA:   QDRIIVK
- PhylomeDB:   A1TKQ6
- BioCyc:   AAVE397945:AAVE_0946-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00580
- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032
- Gene3D:   G3DSA:2.30.33.40
- PANTHER:   PTHR10772
- PRINTS:   PR00297
- SMART:   SM00883

Pfam domain/function: PF00166 Cpn10; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 10347; Mature: 10216

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRPLHDRVIVKRIESETTTASGIVIPDNAAEKPDQGVVLAVGPGKKNDKGELSVLSVK
CCCCCCCHHHEEEECCCCCCCCCCEEECCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEE
VGDRVLFGKYSGQTVKVNGDELLVMKEDDLFAVVEK
CCCEEEEEECCCCEEEECCCEEEEEECCCEEEEEEC
>Mature Secondary Structure 
SLRPLHDRVIVKRIESETTTASGIVIPDNAAEKPDQGVVLAVGPGKKNDKGELSVLSVK
CCCCCCHHHEEEECCCCCCCCCCEEECCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEE
VGDRVLFGKYSGQTVKVNGDELLVMKEDDLFAVVEK
CCCEEEEEECCCCEEEECCCEEEEEECCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA