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The map label for this gene is pimA [H]

Identifier: 120609658

GI number: 120609658

Start: 1054142

End: 1055983

Strand: Reverse

Name: pimA [H]

Synonym: Aave_0964

Alternate gene names: 120609658

Gene position: 1055983-1054142 (Counterclockwise)

Preceding gene: 120609659

Following gene: 120609640

Centisome position: 19.73

GC content: 64.88

Gene sequence:

>1842_bases
ATGGCGCTGCGCGTACTGCACATCGGCAAGTTCTTTCCGCCACACCTCGGTGGCATGGAGATCTTTCTCGCCGAGCTGAT
CGAGGCCCAGCGGGCCCAGGGTATCGATGCATGCGCGCTGGTGCATGGCACGCCCCTGCCCGGCGATCCGCCATGGCTCG
TGCGGGTGCCCGTGCAGTTCAACCTCGTCTATGCTCCGATTGCCATTGGATTCCGCAAGGCCCTGGCACGAGCCATACGC
CAGTTCCGCCCGGACATCCTGCATCTGCACCTGCCGAACAACTCGGCGCTCTGGGCGCTCACTCTGCCCGCCGCACGCAA
GGTGCCATATGTGGTGCATTGGCATTCCGACGTGGTGGTGTCGGACATCAAGCTTTCGGTGGCACTGGCCTACATGCTCT
ACAAGCCTTTCGAGCATGCTGTCCTCGACCGCGCCCACCTCATCTTCGCCACCTCGCCGCCGTATCTCGACGCATCGCCT
GCCCTGCAGCCCTGGCGCGGCAAATGCTCCGTCATACCGCTGGGCACCAAGCTCCAGCACGCACAGCCGCCGGAAGCCCT
GGCTCCGGCCATGCGCTGGAAGGCCGGGACGGCACTGCGCCTGCTCTCCATCGGAAGGCTGACCTATTACAAGGGCTTCG
AGACGCTGATTCAGGCCGTCCAGGCCTTACCGGAGGTGGAATTGCTGATCGCGGGCGAAGGGGAATTGCGCCCGCACCTG
GAAGCGCTGATACGTGACACGAGGCCGCCGGGACAAGAGTCCAGGGTGCGGTTGCTGGGGGCCGTCCAGGAATCTGAAAA
ACACGGGCTACTGCGCGATTGCGATGTCTTCTGCCTCGCCTCCAGGGAACGGACCGAAGCGTTCGGCATCGTTCTGCTGG
AGGCGATGATGCATCGCAAGCCCTGTATCGTGACCGACCTCCCCGGCTCGGGCATGCCTTGGGTGGTGTCTTACGCGCAT
GCGGGCCTGCACGTGCCCATCGAGGATGTTGACAGTTGGCGCAGCACCATCGCACGGCTGCAGCACGACGCCCGCCTGAG
GCGCCAGTTGGGCGAGGCCGGCCATCAGGCGCTGCTCCAATCGTTCGATATACGCCGGTGCGAGCGCGCACTGGCCGTGC
AGTACCGGCACGTTGCCCCCGGCGAAGTCCTTAAGGCGGTCCAGGGCCAACCGCTGGTGGTGATTTCCACCCGCAACCAT
GCGGCCACCATCGGCGCGCTCATTGCGCGGATCCGTTCCCTGGTGCAGGCCGACGTGCTCGTGGTGGACGACCGCAGCAC
CGACGGCACGTGCCACCTGGCCGAGAATGCGGGTGCCCAGGTTTTGCGGCCCCTGCTCGCCATGACCACCTGGGGAAGCT
TGCAGACTGGCCTGCGCTTCGGCCTGGCACGCGGATACGAGACAGTGGTCACCATCGACGCAGACGGCCGCTACGAAGCG
GAGGAAATTCCTGCACTGCTGGCGCACCGCGCTGCCGCTGACGTGATCGTCAGCTACTTTCCCGCCCGCAACAGCTGGGT
GCGCGATCTGGCCTGGCAATGGTTCCGACGGCTTACCGGCTTCGGTCTGCGGGATTTCGTATCCGGTTTCCGGCTCTACA
ACCGTGCGGCACTGCAGGTCGCGACCTCCACGGAAGCCACGCTGCTGGACTATCAGGACATCGGCACCCTGCTGCTGCTC
AGACGCCGCGGCATGCGAGTGGCCGAGCTGGCGTTGTCATTGCGCACCGCCCAGACGGACCGCTCGAAAATCTTCCAGTC
CTGGCGCCATGCACTGCGGTACATGGCAGTGTCTTCCCTGTTGTGCATTGCCCATGCACGGTCGGACAAAGTGGCGGATT
GA

Upstream 100 bases:

>100_bases
GGACCCGCGCAATCCGCAGTACCCGCAAGTGCGCGCGCAGATCGCCGCCGCCAGGAAGTAGGCGGCCTCGGCCTGCCCTT
CGCACGAAGGCCCCGGACAT

Downstream 100 bases:

>100_bases
CCCGGAACTACCGTGGATCCTTCTATCTCAATATATCGCGCATACGTTCGATGAACCGGGCCTCGGAGAAGTGCTCCGCG
CGTGACACGCAGGCAGCCTG

Product: group 1 glycosyl transferase

Products: NA

Alternate protein names: Alpha-mannosyltransferase; Guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase; Phosphatidylinositol alpha-mannosyltransferase; PI alpha-mannosyltransferase [H]

Number of amino acids: Translated: 613; Mature: 612

Protein sequence:

>613_residues
MALRVLHIGKFFPPHLGGMEIFLAELIEAQRAQGIDACALVHGTPLPGDPPWLVRVPVQFNLVYAPIAIGFRKALARAIR
QFRPDILHLHLPNNSALWALTLPAARKVPYVVHWHSDVVVSDIKLSVALAYMLYKPFEHAVLDRAHLIFATSPPYLDASP
ALQPWRGKCSVIPLGTKLQHAQPPEALAPAMRWKAGTALRLLSIGRLTYYKGFETLIQAVQALPEVELLIAGEGELRPHL
EALIRDTRPPGQESRVRLLGAVQESEKHGLLRDCDVFCLASRERTEAFGIVLLEAMMHRKPCIVTDLPGSGMPWVVSYAH
AGLHVPIEDVDSWRSTIARLQHDARLRRQLGEAGHQALLQSFDIRRCERALAVQYRHVAPGEVLKAVQGQPLVVISTRNH
AATIGALIARIRSLVQADVLVVDDRSTDGTCHLAENAGAQVLRPLLAMTTWGSLQTGLRFGLARGYETVVTIDADGRYEA
EEIPALLAHRAAADVIVSYFPARNSWVRDLAWQWFRRLTGFGLRDFVSGFRLYNRAALQVATSTEATLLDYQDIGTLLLL
RRRGMRVAELALSLRTAQTDRSKIFQSWRHALRYMAVSSLLCIAHARSDKVAD

Sequences:

>Translated_613_residues
MALRVLHIGKFFPPHLGGMEIFLAELIEAQRAQGIDACALVHGTPLPGDPPWLVRVPVQFNLVYAPIAIGFRKALARAIR
QFRPDILHLHLPNNSALWALTLPAARKVPYVVHWHSDVVVSDIKLSVALAYMLYKPFEHAVLDRAHLIFATSPPYLDASP
ALQPWRGKCSVIPLGTKLQHAQPPEALAPAMRWKAGTALRLLSIGRLTYYKGFETLIQAVQALPEVELLIAGEGELRPHL
EALIRDTRPPGQESRVRLLGAVQESEKHGLLRDCDVFCLASRERTEAFGIVLLEAMMHRKPCIVTDLPGSGMPWVVSYAH
AGLHVPIEDVDSWRSTIARLQHDARLRRQLGEAGHQALLQSFDIRRCERALAVQYRHVAPGEVLKAVQGQPLVVISTRNH
AATIGALIARIRSLVQADVLVVDDRSTDGTCHLAENAGAQVLRPLLAMTTWGSLQTGLRFGLARGYETVVTIDADGRYEA
EEIPALLAHRAAADVIVSYFPARNSWVRDLAWQWFRRLTGFGLRDFVSGFRLYNRAALQVATSTEATLLDYQDIGTLLLL
RRRGMRVAELALSLRTAQTDRSKIFQSWRHALRYMAVSSLLCIAHARSDKVAD
>Mature_612_residues
ALRVLHIGKFFPPHLGGMEIFLAELIEAQRAQGIDACALVHGTPLPGDPPWLVRVPVQFNLVYAPIAIGFRKALARAIRQ
FRPDILHLHLPNNSALWALTLPAARKVPYVVHWHSDVVVSDIKLSVALAYMLYKPFEHAVLDRAHLIFATSPPYLDASPA
LQPWRGKCSVIPLGTKLQHAQPPEALAPAMRWKAGTALRLLSIGRLTYYKGFETLIQAVQALPEVELLIAGEGELRPHLE
ALIRDTRPPGQESRVRLLGAVQESEKHGLLRDCDVFCLASRERTEAFGIVLLEAMMHRKPCIVTDLPGSGMPWVVSYAHA
GLHVPIEDVDSWRSTIARLQHDARLRRQLGEAGHQALLQSFDIRRCERALAVQYRHVAPGEVLKAVQGQPLVVISTRNHA
ATIGALIARIRSLVQADVLVVDDRSTDGTCHLAENAGAQVLRPLLAMTTWGSLQTGLRFGLARGYETVVTIDADGRYEAE
EIPALLAHRAAADVIVSYFPARNSWVRDLAWQWFRRLTGFGLRDFVSGFRLYNRAALQVATSTEATLLDYQDIGTLLLLR
RRGMRVAELALSLRTAQTDRSKIFQSWRHALRYMAVSSLLCIAHARSDKVAD

Specific function: Catalyzes the addition of a mannose residue from GDP-D- mannose to the position 2 of a phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Contrary to pimB, the mannosyltransferase pim

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.57 [H]

Molecular weight: Translated: 68144; Mature: 68013

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALRVLHIGKFFPPHLGGMEIFLAELIEAQRAQGIDACALVHGTPLPGDPPWLVRVPVQF
CEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEECEEE
NLVYAPIAIGFRKALARAIRQFRPDILHLHLPNNSALWALTLPAARKVPYVVHWHSDVVV
EEEEHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEECCCCCCCCEEEEECCCEEE
SDIKLSVALAYMLYKPFEHAVLDRAHLIFATSPPYLDASPALQPWRGKCSVIPLGTKLQH
HHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCC
AQPPEALAPAMRWKAGTALRLLSIGRLTYYKGFETLIQAVQALPEVELLIAGEGELRPHL
CCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHH
EALIRDTRPPGQESRVRLLGAVQESEKHGLLRDCDVFCLASRERTEAFGIVLLEAMMHRK
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCC
PCIVTDLPGSGMPWVVSYAHAGLHVPIEDVDSWRSTIARLQHDARLRRQLGEAGHQALLQ
CEEEEECCCCCCCHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFDIRRCERALAVQYRHVAPGEVLKAVQGQPLVVISTRNHAATIGALIARIRSLVQADVL
HHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCEE
VVDDRSTDGTCHLAENAGAQVLRPLLAMTTWGSLQTGLRFGLARGYETVVTIDADGRYEA
EEECCCCCCEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEEECCCCCCH
EEIPALLAHRAAADVIVSYFPARNSWVRDLAWQWFRRLTGFGLRDFVSGFRLYNRAALQV
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEE
ATSTEATLLDYQDIGTLLLLRRRGMRVAELALSLRTAQTDRSKIFQSWRHALRYMAVSSL
ECCCCCEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LCIAHARSDKVAD
HHHHHCCCCCCCC
>Mature Secondary Structure 
ALRVLHIGKFFPPHLGGMEIFLAELIEAQRAQGIDACALVHGTPLPGDPPWLVRVPVQF
EEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEECEEE
NLVYAPIAIGFRKALARAIRQFRPDILHLHLPNNSALWALTLPAARKVPYVVHWHSDVVV
EEEEHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEECCCCCCCCEEEEECCCEEE
SDIKLSVALAYMLYKPFEHAVLDRAHLIFATSPPYLDASPALQPWRGKCSVIPLGTKLQH
HHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCC
AQPPEALAPAMRWKAGTALRLLSIGRLTYYKGFETLIQAVQALPEVELLIAGEGELRPHL
CCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHH
EALIRDTRPPGQESRVRLLGAVQESEKHGLLRDCDVFCLASRERTEAFGIVLLEAMMHRK
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCC
PCIVTDLPGSGMPWVVSYAHAGLHVPIEDVDSWRSTIARLQHDARLRRQLGEAGHQALLQ
CEEEEECCCCCCCHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFDIRRCERALAVQYRHVAPGEVLKAVQGQPLVVISTRNHAATIGALIARIRSLVQADVL
HHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCEE
VVDDRSTDGTCHLAENAGAQVLRPLLAMTTWGSLQTGLRFGLARGYETVVTIDADGRYEA
EEECCCCCCEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEEECCCCCCH
EEIPALLAHRAAADVIVSYFPARNSWVRDLAWQWFRRLTGFGLRDFVSGFRLYNRAALQV
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEE
ATSTEATLLDYQDIGTLLLLRRRGMRVAELALSLRTAQTDRSKIFQSWRHALRYMAVSSL
ECCCCCEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LCIAHARSDKVAD
HHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12068013 [H]