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The map label for this gene is tal

Identifier: 120609637

GI number: 120609637

Start: 1027687

End: 1028634

Strand: Direct

Name: tal

Synonym: Aave_0943

Alternate gene names: 120609637

Gene position: 1027687-1028634 (Clockwise)

Preceding gene: 120609633

Following gene: 120609638

Centisome position: 19.2

GC content: 68.88

Gene sequence:

>948_bases
ATGAACCAACTCGACGCCCTCAAGCAGGTCACCACCGTGGTGGCCGACACGGGCGACTTCCGCCAGCTCGGCGCGTACCG
CCCCCAGGACGCGACCACCAATCCGTCCCTGATCCTCAAGGCCGTCCAGAAGGCCGACTACGCCCCCCTGCTGCAGGAAT
CAGTGGAGCGCTGGCGCGGCCGCGCGCTCGACGAGATCATGGACCGGCTCATCGTGCGCTTCGGCTGCGAGATCCTCTCG
CTGATCCCCGGGCGCGTGTCGACCGAAGTGGACGCGCGCCTGTCCTTCGACACCATGGCCACCGTGACGCGCGGCGAGCG
CATCATTGACCTCTACCGCGCCGAAGGCGTGGACACTGCCCGCGTGCTCATCAAGATCGCCGCCACCTGGGAAGGCATCG
AAGCCGCGCGCATCCTGGAAGAGCGCGGCATCCACACCAACCTCACGCTGCTGTTCTCGCCCGTGCAGGCCGTGGCCTGC
GGCGCCGCCCGGGTGCAGCTGATCTCGCCCTTCGTGGGCCGCATCTACGACTGGTACAAGAAGCAGGCTGGCGCCCAGTG
GGACGAGGCCGCGATGGCCGGCGCCAACGACCCGGGCGTGCAGTCGGTGCGCCAGATCTACCAGTACTACAAGCACTTCG
GCATCCGCACCGAGGTCATGGGCGCGAGCTTCCGCAACATCGGCCAGATCACGGCGCTCGCCGGCTGCGACCTGCTCACC
ATCGCGCCGGAACTGCTCGCCCAGCTGGCGGCGTCCGAAGCACCCCTGGAGCGCGCGCTCGACCCGGCATCCGCCAAGGA
CCTCGAACTGCAGCCCGTGCAGTACGACGAACCGGGCTTCCGCTACGCGCTCAACGCCGACGCCATGGCCACCGAGAAGC
TGGCCGAGGGCATCCGCGCCTTCGCGGCCGACGCGGCCAAGCTGGAACAGATGGTGCTGGCGGCATGA

Upstream 100 bases:

>100_bases
CCCCCCTACACTCGCCGGTGGCGCAGCGCGCGGTTCCGGGCCCTTTCTTACCAGGGCACGGCAGTCCACCGCGACCGCCC
CCAACCACCCGGAGGATTGC

Downstream 100 bases:

>100_bases
CGGGGATGACCGCCATGACGATGCCCGTTCCCGCCCGCGTGCGCTGCGACCGCACCGCCGCCTGGGCCGCACTGCAGGCG
CACTACGAGGCCGCCGGCCG

Product: transaldolase B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MNQLDALKQVTTVVADTGDFRQLGAYRPQDATTNPSLILKAVQKADYAPLLQESVERWRGRALDEIMDRLIVRFGCEILS
LIPGRVSTEVDARLSFDTMATVTRGERIIDLYRAEGVDTARVLIKIAATWEGIEAARILEERGIHTNLTLLFSPVQAVAC
GAARVQLISPFVGRIYDWYKKQAGAQWDEAAMAGANDPGVQSVRQIYQYYKHFGIRTEVMGASFRNIGQITALAGCDLLT
IAPELLAQLAASEAPLERALDPASAKDLELQPVQYDEPGFRYALNADAMATEKLAEGIRAFAADAAKLEQMVLAA

Sequences:

>Translated_315_residues
MNQLDALKQVTTVVADTGDFRQLGAYRPQDATTNPSLILKAVQKADYAPLLQESVERWRGRALDEIMDRLIVRFGCEILS
LIPGRVSTEVDARLSFDTMATVTRGERIIDLYRAEGVDTARVLIKIAATWEGIEAARILEERGIHTNLTLLFSPVQAVAC
GAARVQLISPFVGRIYDWYKKQAGAQWDEAAMAGANDPGVQSVRQIYQYYKHFGIRTEVMGASFRNIGQITALAGCDLLT
IAPELLAQLAASEAPLERALDPASAKDLELQPVQYDEPGFRYALNADAMATEKLAEGIRAFAADAAKLEQMVLAA
>Mature_315_residues
MNQLDALKQVTTVVADTGDFRQLGAYRPQDATTNPSLILKAVQKADYAPLLQESVERWRGRALDEIMDRLIVRFGCEILS
LIPGRVSTEVDARLSFDTMATVTRGERIIDLYRAEGVDTARVLIKIAATWEGIEAARILEERGIHTNLTLLFSPVQAVAC
GAARVQLISPFVGRIYDWYKKQAGAQWDEAAMAGANDPGVQSVRQIYQYYKHFGIRTEVMGASFRNIGQITALAGCDLLT
IAPELLAQLAASEAPLERALDPASAKDLELQPVQYDEPGFRYALNADAMATEKLAEGIRAFAADAAKLEQMVLAA

Specific function: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway

COG id: COG0176

COG function: function code G; Transaldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transaldolase family. Type 1 subfamily

Homologues:

Organism=Homo sapiens, GI5803187, Length=316, Percent_Identity=55.379746835443, Blast_Score=333, Evalue=1e-91,
Organism=Escherichia coli, GI1786189, Length=318, Percent_Identity=53.4591194968553, Blast_Score=317, Evalue=7e-88,
Organism=Escherichia coli, GI1788807, Length=320, Percent_Identity=52.1875, Blast_Score=308, Evalue=4e-85,
Organism=Caenorhabditis elegans, GI25153750, Length=321, Percent_Identity=53.8940809968847, Blast_Score=322, Evalue=2e-88,
Organism=Caenorhabditis elegans, GI25153752, Length=167, Percent_Identity=54.4910179640719, Blast_Score=174, Evalue=5e-44,
Organism=Caenorhabditis elegans, GI17570473, Length=93, Percent_Identity=58.0645161290323, Blast_Score=101, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6321480, Length=321, Percent_Identity=52.6479750778816, Blast_Score=317, Evalue=1e-87,
Organism=Saccharomyces cerevisiae, GI6323386, Length=321, Percent_Identity=55.7632398753894, Blast_Score=313, Evalue=2e-86,
Organism=Drosophila melanogaster, GI45549185, Length=319, Percent_Identity=54.858934169279, Blast_Score=345, Evalue=2e-95,

Paralogues:

None

Copy number: 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 900 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase,

Swissprot (AC and ID): TAL_ACIAC (A1TKQ3)

Other databases:

- EMBL:   CP000512
- RefSeq:   YP_969315.1
- ProteinModelPortal:   A1TKQ3
- SMR:   A1TKQ3
- STRING:   A1TKQ3
- GeneID:   4665952
- GenomeReviews:   CP000512_GR
- KEGG:   aav:Aave_0943
- NMPDR:   fig|397945.5.peg.821
- eggNOG:   COG0176
- HOGENOM:   HBG286747
- OMA:   GCEILAI
- PhylomeDB:   A1TKQ3
- ProtClustDB:   PRK05269
- BioCyc:   AAVE397945:AAVE_0943-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00492
- InterPro:   IPR013785
- InterPro:   IPR001585
- InterPro:   IPR004730
- InterPro:   IPR018225
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10683
- PANTHER:   PTHR10683:SF3
- TIGRFAMs:   TIGR00874

Pfam domain/function: PF00923 Transaldolase

EC number: =2.2.1.2

Molecular weight: Translated: 34546; Mature: 34546

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS01054 TRANSALDOLASE_1; PS00958 TRANSALDOLASE_2

Important sites: ACT_SITE 125-125

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQLDALKQVTTVVADTGDFRQLGAYRPQDATTNPSLILKAVQKADYAPLLQESVERWRG
CCHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHC
RALDEIMDRLIVRFGCEILSLIPGRVSTEVDARLSFDTMATVTRGERIIDLYRAEGVDTA
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHHCCHHHHHHHHHCCCHHH
RVLIKIAATWEGIEAARILEERGIHTNLTLLFSPVQAVACGAARVQLISPFVGRIYDWYK
HHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQAGAQWDEAAMAGANDPGVQSVRQIYQYYKHFGIRTEVMGASFRNIGQITALAGCDLLT
HHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHCCHHHH
IAPELLAQLAASEAPLERALDPASAKDLELQPVQYDEPGFRYALNADAMATEKLAEGIRA
HHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHH
FAADAAKLEQMVLAA
HHHHHHHHHHHHHCC
>Mature Secondary Structure
MNQLDALKQVTTVVADTGDFRQLGAYRPQDATTNPSLILKAVQKADYAPLLQESVERWRG
CCHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHC
RALDEIMDRLIVRFGCEILSLIPGRVSTEVDARLSFDTMATVTRGERIIDLYRAEGVDTA
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHHCCHHHHHHHHHCCCHHH
RVLIKIAATWEGIEAARILEERGIHTNLTLLFSPVQAVACGAARVQLISPFVGRIYDWYK
HHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQAGAQWDEAAMAGANDPGVQSVRQIYQYYKHFGIRTEVMGASFRNIGQITALAGCDLLT
HHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHCCHHHH
IAPELLAQLAASEAPLERALDPASAKDLELQPVQYDEPGFRYALNADAMATEKLAEGIRA
HHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHH
FAADAAKLEQMVLAA
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA