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The map label for this gene is gsiC [H]

Identifier: 120609628

GI number: 120609628

Start: 1015704

End: 1016684

Strand: Direct

Name: gsiC [H]

Synonym: Aave_0934

Alternate gene names: 120609628

Gene position: 1015704-1016684 (Clockwise)

Preceding gene: 120609627

Following gene: 120609629

Centisome position: 18.98

GC content: 65.44

Gene sequence:

>981_bases
ATGCTTGCCTTCATTCTGAGACGCCTCATCCAGGCCGTGATCGTCATGGTCGCGGTGGCTTTCATCTCCTTCATGCTGTT
CCAGTATGTGGGCGATCCCGTCACCTTCCTGCTCGGGCAGGACGCCACGCCGGACCAGATACGGGACATGCGTGCGGCAC
TCGGGCTGGACCAGCCTTTCATCGTGCAGTTCTGGCATTTCCTCGTGAATGCCGCTCAGGGGGAGTTCGGACTCAGCCTC
CGGCAGGGGGCCAAGGTGTCCAGCCTCATTGCCGAGCGTTTCCCGGCCACGCTGGAGCTGGCGCTGGTCGCCGCTGTCCT
GGCCCTGGTGGTCGGCGTGCCCATGGGGGTCTATGCGGCGCTGCGTCGCGGCACCTTCACGAGCCAGCTCTTCATGACGC
TGTCCCTGCTGGGGGTGTCGCTGCCCACGTTCCTCATCGGCATCCTGCTGATCCTCGTGTTCGCCGTCCACCTGGGCTGG
TTCCCGAGCTTCGGGCGCGGTCCGGTCACGCAGGTCGGCTGGTGGAGCACGGGCCTGCTCAGTGCCAAGGGCTGGCACCA
CATCACGCTGCCGGCGGTGACGCTGGCCATCTTTCAGCTCACGCTCATCATGCGCCTCGTGCGCGCCGAGATGCTGGAGG
TGCTGCGCACCGACTACATCAAGTTCGCCCGCGCCCGCGGCCTGTCCGACCGGGCCATCCATTTCGGGCATGCCCTGAAG
AACACGCTGGTGCCGGTGATGACGATCACCGGCCTGCAACTGGGCGGCCTCATCGCCTTCGCCATCATCACCGAGACGGT
GTTCCAGTGGCCCGGCATGGGCCTGCTCTTCATCCAGGCGGTGACGTTCGCGGACATTCCCGTGATGGCGGCCTACCTCT
GCCTGATCGCACTGATCTTCGTGGTGATCAACCTGGTCGTGGACCTGCTGTATTTCGCGGTCGATCCCCGCCTGCGGGTG
GGCAAGGCGGGAGGGCACTGA

Upstream 100 bases:

>100_bases
CGGGGCCGGGCTTGGGCCGACAACCATCCGCGATGGCCCGGGTATTGCATGCGGTGGCCATATGCCCTGCTAGCATGCCC
GCTTCTCTGCCGTTCCTACG

Downstream 100 bases:

>100_bases
CATGGCGGTCGCAGCAGCCAAGCCGGCACTGTCCGCGCCGCCCCGCCTGCGGGCCGGCGGCCGCGCCTTCGCCCACATCG
CCCAGTTCCACCCCGAGCTG

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MLAFILRRLIQAVIVMVAVAFISFMLFQYVGDPVTFLLGQDATPDQIRDMRAALGLDQPFIVQFWHFLVNAAQGEFGLSL
RQGAKVSSLIAERFPATLELALVAAVLALVVGVPMGVYAALRRGTFTSQLFMTLSLLGVSLPTFLIGILLILVFAVHLGW
FPSFGRGPVTQVGWWSTGLLSAKGWHHITLPAVTLAIFQLTLIMRLVRAEMLEVLRTDYIKFARARGLSDRAIHFGHALK
NTLVPVMTITGLQLGGLIAFAIITETVFQWPGMGLLFIQAVTFADIPVMAAYLCLIALIFVVINLVVDLLYFAVDPRLRV
GKAGGH

Sequences:

>Translated_326_residues
MLAFILRRLIQAVIVMVAVAFISFMLFQYVGDPVTFLLGQDATPDQIRDMRAALGLDQPFIVQFWHFLVNAAQGEFGLSL
RQGAKVSSLIAERFPATLELALVAAVLALVVGVPMGVYAALRRGTFTSQLFMTLSLLGVSLPTFLIGILLILVFAVHLGW
FPSFGRGPVTQVGWWSTGLLSAKGWHHITLPAVTLAIFQLTLIMRLVRAEMLEVLRTDYIKFARARGLSDRAIHFGHALK
NTLVPVMTITGLQLGGLIAFAIITETVFQWPGMGLLFIQAVTFADIPVMAAYLCLIALIFVVINLVVDLLYFAVDPRLRV
GKAGGH
>Mature_326_residues
MLAFILRRLIQAVIVMVAVAFISFMLFQYVGDPVTFLLGQDATPDQIRDMRAALGLDQPFIVQFWHFLVNAAQGEFGLSL
RQGAKVSSLIAERFPATLELALVAAVLALVVGVPMGVYAALRRGTFTSQLFMTLSLLGVSLPTFLIGILLILVFAVHLGW
FPSFGRGPVTQVGWWSTGLLSAKGWHHITLPAVTLAIFQLTLIMRLVRAEMLEVLRTDYIKFARARGLSDRAIHFGHALK
NTLVPVMTITGLQLGGLIAFAIITETVFQWPGMGLLFIQAVTFADIPVMAAYLCLIALIFVVINLVVDLLYFAVDPRLRV
GKAGGH

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=320, Percent_Identity=38.4375, Blast_Score=233, Evalue=1e-62,
Organism=Escherichia coli, GI1789965, Length=339, Percent_Identity=37.4631268436578, Blast_Score=218, Evalue=4e-58,
Organism=Escherichia coli, GI1789888, Length=330, Percent_Identity=36.3636363636364, Blast_Score=203, Evalue=1e-53,
Organism=Escherichia coli, GI1787497, Length=322, Percent_Identity=32.9192546583851, Blast_Score=175, Evalue=3e-45,
Organism=Escherichia coli, GI1787761, Length=338, Percent_Identity=37.8698224852071, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1787550, Length=270, Percent_Identity=33.3333333333333, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1788504, Length=287, Percent_Identity=28.2229965156794, Blast_Score=114, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35706; Mature: 35706

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAFILRRLIQAVIVMVAVAFISFMLFQYVGDPVTFLLGQDATPDQIRDMRAALGLDQPF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHCCCCHH
IVQFWHFLVNAAQGEFGLSLRQGAKVSSLIAERFPATLELALVAAVLALVVGVPMGVYAA
HHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHH
LRRGTFTSQLFMTLSLLGVSLPTFLIGILLILVFAVHLGWFPSFGRGPVTQVGWWSTGLL
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
SAKGWHHITLPAVTLAIFQLTLIMRLVRAEMLEVLRTDYIKFARARGLSDRAIHFGHALK
CCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
NTLVPVMTITGLQLGGLIAFAIITETVFQWPGMGLLFIQAVTFADIPVMAAYLCLIALIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVINLVVDLLYFAVDPRLRVGKAGGH
HHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MLAFILRRLIQAVIVMVAVAFISFMLFQYVGDPVTFLLGQDATPDQIRDMRAALGLDQPF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHCCCCHH
IVQFWHFLVNAAQGEFGLSLRQGAKVSSLIAERFPATLELALVAAVLALVVGVPMGVYAA
HHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHH
LRRGTFTSQLFMTLSLLGVSLPTFLIGILLILVFAVHLGWFPSFGRGPVTQVGWWSTGLL
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
SAKGWHHITLPAVTLAIFQLTLIMRLVRAEMLEVLRTDYIKFARARGLSDRAIHFGHALK
CCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
NTLVPVMTITGLQLGGLIAFAIITETVFQWPGMGLLFIQAVTFADIPVMAAYLCLIALIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVINLVVDLLYFAVDPRLRVGKAGGH
HHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]