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The map label for this gene is hipO [H]

Identifier: 120609629

GI number: 120609629

Start: 1016686

End: 1017933

Strand: Direct

Name: hipO [H]

Synonym: Aave_0935

Alternate gene names: 120609629

Gene position: 1016686-1017933 (Clockwise)

Preceding gene: 120609628

Following gene: 120609630

Centisome position: 18.99

GC content: 69.87

Gene sequence:

>1248_bases
ATGGCGGTCGCAGCAGCCAAGCCGGCACTGTCCGCGCCGCCCCGCCTGCGGGCCGGCGGCCGCGCCTTCGCCCACATCGC
CCAGTTCCACCCCGAGCTGACCGCGTTCCGCCGCGACCTGCATGCCCATCCCGAACTGGGTTTCGAAGAGGTCTATACGG
GCTCCCGCGTGAAGGAGGCGCTCAAGGTCTGCGGGGTGGACGAGATCCACGACGGCATCGGCCGTACCGGCATCGTGGCG
GTGATCCACGGGCGCAGCCGTTCCAGCGGCAGCATGATCGGCCTGCGCGCCGACATGGACGCCCTGCCCATGTCGGAGCA
GAACGAGTTCACCTGGAAGTCCTGCAAACCCGGACTCATGCACGGCTGCGGTCACGACGGCCACACGGCCATGCTGGTGG
GGGCCGCGCGCTACCTCGCCGCCACGCGCCATTTCGACGGCACGGCCGTGCTCATCTTCCAGCCCGGCGAGGAGGGCTTC
GGCGGTGCGCGCGTGATGATCGAGGACGGCCTGTTCGAGCGCTTTCCCGTGCAGTCGGTCTATGCCATGCACAACTGGCC
GGCCATGCAGCCGGGCACCATCGGACTCAATTCCGGGGCGATGATGGCATCGGCCGACCGCATCACCATCGAGATCACCG
GCCGCGGCGGACATGGTGCGCACCCGTACCAGACGGTGGACGTGGTGCTCGTGGCCGCGCACATCATCACCGCGGTGCAG
GGCATCGTCTCGCGCAACGTGCGCCCGCTCGACAGCGCGGTGATCAGCCTCTGCGCCATGCAGGCGGGCGACCTCGGGGC
CTTCAGCGTGCTGCCCGGCACGGCCACGCTGGTGGGCACGGTGCGCACGTTCTCGCCCGCGGTGCAGGAGATGATCGAGC
AGCGCCTCAAGGACCTGTGCAGCGCGGTGGCGCTGGGCTTCGGCGCCACGGCCTCCGTGCGCTACGAACGCATCTACCCC
GCGACCATCAACACCGAAAGCGACGCGCAGTTCGCGGGCGACGTGGCAGTGTCGATCGTCGGGGCCGAGAACGTGGTGCG
CGACCTGGAGCCCAGCATGGGCGCGGAAGACTTCTCCTTCATGCTGCAGAGCAAGCCGGGCGCCTACCTGCGCATCGGGC
AGGGCACCGGGCCCGGCCACAGCGCGCTGCACAACAGCCGGTACGACTTCAACGACGAGATCCTGCCCCTGGGCGCCGCG
CTGCACGCGGGCCTGGTCGAGCAGGCCATGCCGCTGGCAGCGGTCTGA

Upstream 100 bases:

>100_bases
CTGATCGCACTGATCTTCGTGGTGATCAACCTGGTCGTGGACCTGCTGTATTTCGCGGTCGATCCCCGCCTGCGGGTGGG
CAAGGCGGGAGGGCACTGAC

Downstream 100 bases:

>100_bases
GGTATGACGATGAATTTCCCACGCACGGCATTGCGCGCCGCCTTCGGCGCCTCCCTGATCGCGGCGGCCTGCATGGCGGG
CGCGCAGACCATCCGGGTCG

Product: amidohydrolase

Products: NA

Alternate protein names: Benzoylglycine amidohydrolase; Hippuricase [H]

Number of amino acids: Translated: 415; Mature: 414

Protein sequence:

>415_residues
MAVAAAKPALSAPPRLRAGGRAFAHIAQFHPELTAFRRDLHAHPELGFEEVYTGSRVKEALKVCGVDEIHDGIGRTGIVA
VIHGRSRSSGSMIGLRADMDALPMSEQNEFTWKSCKPGLMHGCGHDGHTAMLVGAARYLAATRHFDGTAVLIFQPGEEGF
GGARVMIEDGLFERFPVQSVYAMHNWPAMQPGTIGLNSGAMMASADRITIEITGRGGHGAHPYQTVDVVLVAAHIITAVQ
GIVSRNVRPLDSAVISLCAMQAGDLGAFSVLPGTATLVGTVRTFSPAVQEMIEQRLKDLCSAVALGFGATASVRYERIYP
ATINTESDAQFAGDVAVSIVGAENVVRDLEPSMGAEDFSFMLQSKPGAYLRIGQGTGPGHSALHNSRYDFNDEILPLGAA
LHAGLVEQAMPLAAV

Sequences:

>Translated_415_residues
MAVAAAKPALSAPPRLRAGGRAFAHIAQFHPELTAFRRDLHAHPELGFEEVYTGSRVKEALKVCGVDEIHDGIGRTGIVA
VIHGRSRSSGSMIGLRADMDALPMSEQNEFTWKSCKPGLMHGCGHDGHTAMLVGAARYLAATRHFDGTAVLIFQPGEEGF
GGARVMIEDGLFERFPVQSVYAMHNWPAMQPGTIGLNSGAMMASADRITIEITGRGGHGAHPYQTVDVVLVAAHIITAVQ
GIVSRNVRPLDSAVISLCAMQAGDLGAFSVLPGTATLVGTVRTFSPAVQEMIEQRLKDLCSAVALGFGATASVRYERIYP
ATINTESDAQFAGDVAVSIVGAENVVRDLEPSMGAEDFSFMLQSKPGAYLRIGQGTGPGHSALHNSRYDFNDEILPLGAA
LHAGLVEQAMPLAAV
>Mature_414_residues
AVAAAKPALSAPPRLRAGGRAFAHIAQFHPELTAFRRDLHAHPELGFEEVYTGSRVKEALKVCGVDEIHDGIGRTGIVAV
IHGRSRSSGSMIGLRADMDALPMSEQNEFTWKSCKPGLMHGCGHDGHTAMLVGAARYLAATRHFDGTAVLIFQPGEEGFG
GARVMIEDGLFERFPVQSVYAMHNWPAMQPGTIGLNSGAMMASADRITIEITGRGGHGAHPYQTVDVVLVAAHIITAVQG
IVSRNVRPLDSAVISLCAMQAGDLGAFSVLPGTATLVGTVRTFSPAVQEMIEQRLKDLCSAVALGFGATASVRYERIYPA
TINTESDAQFAGDVAVSIVGAENVVRDLEPSMGAEDFSFMLQSKPGAYLRIGQGTGPGHSALHNSRYDFNDEILPLGAAL
HAGLVEQAMPLAAV

Specific function: Required But Not Essential For Aminobenzoyl-Glutamate Utilization. May Participate In Hydrolysis Of Aminobenzoyl- Glutamate To Aminobenzoate, Either Alone Or In Combination With Abgb. [C]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=423, Percent_Identity=27.6595744680851, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.32 [H]

Molecular weight: Translated: 43906; Mature: 43774

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVAAAKPALSAPPRLRAGGRAFAHIAQFHPELTAFRRDLHAHPELGFEEVYTGSRVKEA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHCCCCCCCHHHHHCCHHHHHH
LKVCGVDEIHDGIGRTGIVAVIHGRSRSSGSMIGLRADMDALPMSEQNEFTWKSCKPGLM
HHHCCHHHHHHCCCCCEEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCHHCCCCCHH
HGCGHDGHTAMLVGAARYLAATRHFDGTAVLIFQPGEEGFGGARVMIEDGLFERFPVQSV
HCCCCCCCEEHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEEECCCHHHCCHHHH
YAMHNWPAMQPGTIGLNSGAMMASADRITIEITGRGGHGAHPYQTVDVVLVAAHIITAVQ
HHHCCCCCCCCCCEECCCCCEEEECCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
GIVSRNVRPLDSAVISLCAMQAGDLGAFSVLPGTATLVGTVRTFSPAVQEMIEQRLKDLC
HHHHCCCCHHHHHHHHHHHHCCCCCCCEEECCCCHHEEEHHHHHCHHHHHHHHHHHHHHH
SAVALGFGATASVRYERIYPATINTESDAQFAGDVAVSIVGAENVVRDLEPSMGAEDFSF
HHHHHCCCCCCEEEEEEEECEEECCCCCCHHCCCEEEEEECHHHHHHHCCCCCCCHHHHH
MLQSKPGAYLRIGQGTGPGHSALHNSRYDFNDEILPLGAALHAGLVEQAMPLAAV
HHHCCCCCEEEEECCCCCCHHHHCCCCCCCCCCEEEHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AVAAAKPALSAPPRLRAGGRAFAHIAQFHPELTAFRRDLHAHPELGFEEVYTGSRVKEA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHCCCCCCCHHHHHCCHHHHHH
LKVCGVDEIHDGIGRTGIVAVIHGRSRSSGSMIGLRADMDALPMSEQNEFTWKSCKPGLM
HHHCCHHHHHHCCCCCEEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCHHCCCCCHH
HGCGHDGHTAMLVGAARYLAATRHFDGTAVLIFQPGEEGFGGARVMIEDGLFERFPVQSV
HCCCCCCCEEHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEEECCCHHHCCHHHH
YAMHNWPAMQPGTIGLNSGAMMASADRITIEITGRGGHGAHPYQTVDVVLVAAHIITAVQ
HHHCCCCCCCCCCEECCCCCEEEECCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
GIVSRNVRPLDSAVISLCAMQAGDLGAFSVLPGTATLVGTVRTFSPAVQEMIEQRLKDLC
HHHHCCCCHHHHHHHHHHHHCCCCCCCEEECCCCHHEEEHHHHHCHHHHHHHHHHHHHHH
SAVALGFGATASVRYERIYPATINTESDAQFAGDVAVSIVGAENVVRDLEPSMGAEDFSF
HHHHHCCCCCCEEEEEEEECEEECCCCCCHHCCCEEEEEECHHHHHHHCCCCCCCHHHHH
MLQSKPGAYLRIGQGTGPGHSALHNSRYDFNDEILPLGAALHAGLVEQAMPLAAV
HHHCCCCCEEEEECCCCCCHHHHCCCCCCCCCCEEEHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7730270; 10688204 [H]