Click here to switch to the map view.

The map label for this gene is arsC [H]

Identifier: 120609609

GI number: 120609609

Start: 997511

End: 997888

Strand: Direct

Name: arsC [H]

Synonym: Aave_0915

Alternate gene names: 120609609

Gene position: 997511-997888 (Clockwise)

Preceding gene: 120609608

Following gene: 120609620

Centisome position: 18.64

GC content: 72.49

Gene sequence:

>378_bases
ATGACCGACGCTACACCCGATCCCGACGTCACCATCTACCACAACGCCCGCTGCAGCAATTCGCGCGGTGCGCTCGCCCT
GCTGCGCGAGCACGGCATCGAGCCGCGCATCGTGGACTACCTCGCCGAGCCGCTGGACGAGGCCGCGCTGCGCACGCTGT
TTTCGCAAGTGGGCGGCCCCGTGCGCGCGCTGCTGCGCCCGAAGGAGCCCGCCTGGCAGGCGCTGGGCCTGGACGACGAG
GCCATCGGCGACGAAGCGCTGATCGCGCACGTGGCGCGCCATCCGGAACTGATGAACCGGCCCATCGTGGTCACCCCGCG
CGGCGCGCGCCTGTGCCGGCCGCCGGAGACGGTGCTGGAACTGCTGCCGGCCGGCTGA

Upstream 100 bases:

>100_bases
GTGGGGCTGGTGCCCGTCATTTTGCTGAGCCGCACGCTGCGGGCGTCCGGTTCGCGCTGACCTCCCGCCGGCCTGCGGCG
GCCCGGTCTAGACTCGCCGC

Downstream 100 bases:

>100_bases
GCGGCGGGCGCGCCGGAAGCCGCGCTATTCGCGCGTGACGCGCAGCACTTCCTCGGGGCTCGTGATGCCGGCACGCACCA
GCCGCTCACCGTCCTCGCGC

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenical pump modifier [H]

Number of amino acids: Translated: 125; Mature: 124

Protein sequence:

>125_residues
MTDATPDPDVTIYHNARCSNSRGALALLREHGIEPRIVDYLAEPLDEAALRTLFSQVGGPVRALLRPKEPAWQALGLDDE
AIGDEALIAHVARHPELMNRPIVVTPRGARLCRPPETVLELLPAG

Sequences:

>Translated_125_residues
MTDATPDPDVTIYHNARCSNSRGALALLREHGIEPRIVDYLAEPLDEAALRTLFSQVGGPVRALLRPKEPAWQALGLDDE
AIGDEALIAHVARHPELMNRPIVVTPRGARLCRPPETVLELLPAG
>Mature_124_residues
TDATPDPDVTIYHNARCSNSRGALALLREHGIEPRIVDYLAEPLDEAALRTLFSQVGGPVRALLRPKEPAWQALGLDDEA
IGDEALIAHVARHPELMNRPIVVTPRGARLCRPPETVLELLPAG

Specific function: Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance [H]

COG id: COG1393

COG function: function code P; Arsenate reductase and related proteins, glutaredoxin family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsC family [H]

Homologues:

Organism=Escherichia coli, GI1789918, Length=115, Percent_Identity=47.8260869565217, Blast_Score=110, Evalue=4e-26,
Organism=Escherichia coli, GI1788841, Length=114, Percent_Identity=49.1228070175439, Blast_Score=107, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006659
- InterPro:   IPR006660
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF03960 ArsC [H]

EC number: =1.20.4.1 [H]

Molecular weight: Translated: 13628; Mature: 13497

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDATPDPDVTIYHNARCSNSRGALALLREHGIEPRIVDYLAEPLDEAALRTLFSQVGGP
CCCCCCCCCEEEEECCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCH
VRALLRPKEPAWQALGLDDEAIGDEALIAHVARHPELMNRPIVVTPRGARLCRPPETVLE
HHHHCCCCCCCHHHCCCCCHHCCHHHHHHHHHHCHHHHCCCEEECCCCCCCCCCHHHHHH
LLPAG
HHCCC
>Mature Secondary Structure 
TDATPDPDVTIYHNARCSNSRGALALLREHGIEPRIVDYLAEPLDEAALRTLFSQVGGP
CCCCCCCCEEEEECCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCH
VRALLRPKEPAWQALGLDDEAIGDEALIAHVARHPELMNRPIVVTPRGARLCRPPETVLE
HHHHCCCCCCCHHHCCCCCHHCCHHHHHHHHHHCHHHHCCCEEECCCCCCCCCCHHHHHH
LLPAG
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9006011 [H]